Published in Int Rev Neurobiol on January 01, 1981
The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention. Neurochem Int (2007) 2.11
Tonic release of glutamate by a DIDS-sensitive mechanism in rat hippocampal slices. J Physiol (2005) 1.50
Modeling the effect of glutamate diffusion and uptake on NMDA and non-NMDA receptor saturation. Biophys J (1995) 1.31
Astrocytic regulation of glutamate homeostasis in epilepsy. Glia (2012) 1.26
Brain glutamine synthesis requires neuronal-born aspartate as amino donor for glial glutamate formation. J Cereb Blood Flow Metab (2010) 1.19
Co-compartmentalization of the astroglial glutamate transporter, GLT-1, with glycolytic enzymes and mitochondria. J Neurosci (2011) 1.18
Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA. Front Endocrinol (Lausanne) (2013) 1.07
GABA and Glutamate Transporters in Brain. Front Endocrinol (Lausanne) (2013) 1.06
Synaptic activity and bioenergy homeostasis: implications in brain trauma and neurodegenerative diseases. Front Neurol (2013) 1.02
Long-term regulation of neuronal high-affinity glutamate and glutamine uptake in Aplysia. Proc Natl Acad Sci U S A (2000) 0.99
Glutamate as a neurotransmitter in the healthy brain. J Neural Transm (Vienna) (2014) 0.97
Multiple gamma-Aminobutyric acid plasma membrane transporters (GAT-1, GAT-2, GAT-3) in the rat retina. J Comp Neurol (1996) 0.96
Ubiquitination-mediated internalization and degradation of the astroglial glutamate transporter, GLT-1. Neurochem Int (2008) 0.95
Primary cultures of astrocytes: their value in understanding astrocytes in health and disease. Neurochem Res (2012) 0.89
Expression of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter in the rat retina. J Comp Neurol (1994) 0.86
Metabolic pathways and activity-dependent modulation of glutamate concentration in the human brain. Neurochem Res (2012) 0.86
Astroglial glutamate transporters coordinate excitatory signaling and brain energetics. Neurochem Int (2016) 0.86
Effects of gamma-aminobutyric acid (GABA) agonists and GABA uptake inhibitors on pharmacosensitive and pharmacoresistant epileptiform activity in vitro. Br J Pharmacol (1996) 0.85
Brain to blood glutamate scavenging as a novel therapeutic modality: a review. J Neural Transm (Vienna) (2014) 0.84
Age-dependent glutamate induction of synaptic plasticity in cultured hippocampal neurons. Learn Mem (2006) 0.83
Physiological bases of the K+ and the glutamate/GABA hypotheses of epilepsy. Epilepsy Res (2014) 0.83
Expression of neurotransmitter transport from rat brain mRNA in Xenopus laevis oocytes. Proc Natl Acad Sci U S A (1988) 0.80
Overview of Glutamatergic Dysregulation in Central Pathologies. Biomolecules (2015) 0.79
Displacing hexokinase from mitochondrial voltage-dependent anion channel impairs GLT-1-mediated glutamate uptake but does not disrupt interactions between GLT-1 and mitochondrial proteins. J Neurosci Res (2014) 0.78
A subconvulsive dose of kainate selectively compromises astrocytic metabolism in the mouse brain in vivo. J Cereb Blood Flow Metab (2014) 0.78
Inhibition of high-affinity gamma-aminobutyric acid uptake in primary astrocyte cultures by phorbol esters and phospholipase C. Biochem J (1991) 0.77
Transcriptional Regulation of Glutamate Transporters: From Extracellular Signals to Transcription Factors. Adv Pharmacol (2016) 0.76
Quinazoline-based tricyclic compounds that regulate programmed cell death, induce neuronal differentiation, and are curative in animal models for excitotoxicity and hereditary brain disease. Cell Death Discov (2015) 0.76
Longitudinal imaging reveals subhippocampal dynamics in glutamate levels associated with histopathologic events in a mouse model of tauopathy and healthy mice. Hippocampus (2017) 0.75
Nitric Oxide and Lutein: Function, Performance, and Protection of Neural Tissue. Foods (2015) 0.75
Characteristics and regulation of proline transport in cultured glioblastoma cells. Biochem J (1994) 0.75
Delineation of the Role of Astroglial GABA Transporters in Seizure Control. Neurochem Res (2017) 0.75
Age-related changes of sodium-dependent D-[3H]aspartate and [3H]FK506 binding in rat brain. J Neural Transm (Vienna) (1997) 0.75
Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem (1984) 3.39
Control of GluR1 AMPA receptor function by cAMP-dependent protein kinase. J Neurosci (2000) 3.10
The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48
High affinity glutamate transporters: regulation of expression and activity. Mol Pharmacol (1997) 1.73
Astrocytes: glutamate producers for neurons. J Neurosci Res (1999) 1.62
Pyruvate carboxylase activity in primary cultures of astrocytes and neurons. J Neurochem (1983) 1.31
Direct demonstration by [13C]NMR spectroscopy that glutamine from astrocytes is a precursor for GABA synthesis in neurons. Neurochem Int (1993) 1.28
Dantrolene prevents glutamate cytotoxicity and Ca2+ release from intracellular stores in cultured cerebral cortical neurons. J Neurochem (1991) 1.27
The first immunoglobulin-like neural cell adhesion molecule (NCAM) domain is involved in double-reciprocal interaction with the second immunoglobulin-like NCAM domain and in heparin binding. J Biol Chem (1997) 1.22
Neuronal soluble factors differentially regulate the expression of the GLT1 and GLAST glutamate transporters in cultured astroglia. J Neurochem (1997) 1.19
Experimental studies of the influence of vigabatrin on the GABA system. Br J Clin Pharmacol (1989) 1.15
The high-affinity glutamate transporters GLT1, GLAST, and EAAT4 are regulated via different signalling mechanisms. Neurochem Int (2000) 1.13
Regional cerebral glucose phosphorylation and blood flow after insertion of a microdialysis fiber through the dorsal hippocampus in the rat. J Neurochem (1987) 1.13
Glutamate transport and metabolism in astrocytes. Glia (1997) 1.11
Metabolic fate of 14C-labeled glutamate in astrocytes in primary cultures. J Neurochem (1982) 1.11
The GABA paradox: multiple roles as metabolite, neurotransmitter, and neurodifferentiative agent. J Neurochem (1999) 1.11
Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro. J Neurochem (1985) 1.07
Characterization of uptake and release processes for D- and L-aspartate in primary cultures of astrocytes and cerebellar granule cells. Neurochem Res (1983) 1.05
Effects of GABA analogues of restricted conformation on GABA transport in astrocytes and brain cortex slices and on GABA receptor binding. J Neurochem (1979) 1.05
A possible role of alanine for ammonia transfer between astrocytes and glutamatergic neurons. J Neurochem (2000) 1.04
Robust glycogen shunt activity in astrocytes: Effects of glutamatergic and adrenergic agents. Neuroscience (2008) 1.03
Energy metabolism in glutamatergic neurons, GABAergic neurons and astrocytes in primary cultures. Neurochem Res (1988) 1.03
Metabolic trafficking between neurons and astrocytes: the glutamate/glutamine cycle revisited. Dev Neurosci (1995) 1.02
Cellular distribution and kinetic properties of high-affinity glutamate transporters. Brain Res Bull (1998) 1.01
Acetoacetate and glucose as lipid precursors and energy substrates in primary cultures of astrocytes and neurons from mouse cerebral cortex. J Neurochem (1986) 1.00
Mitochondrial heterogeneity in the brain at the cellular level. J Cereb Blood Flow Metab (1998) 1.00
Purification and characterization of the 4-aminobutyrate--2,ketoglutarate transaminase from mouse brain. Biochemistry (1973) 0.99
Characterization of L-glutamate uptake into and release from astrocytes and neurons cultured from different brain regions. Exp Brain Res (1982) 0.98
Development of excitatory amino acid induced cytotoxicity in cultured neurons. Int J Dev Neurosci (1990) 0.97
Direct evidence that excitotoxicity in cultured neurons is mediated via N-methyl-D-aspartate (NMDA) as well as non-NMDA receptors. J Neurochem (1989) 0.96
Determination of the phospholipid precursor of anandamide and other N-acylethanolamine phospholipids before and after sodium azide-induced toxicity in cultured neocortical neurons. J Neurochem (2000) 0.96
Metabolism of [U-13C5] glutamine in cultured astrocytes studied by NMR spectroscopy: first evidence of astrocytic pyruvate recycling. J Neurochem (1996) 0.96
Transport and metabolism of gamma-aminobutyric acid in neurons and glia: implications for epilepsy. Epilepsia (1983) 0.96
Phosphate activated glutaminase activity and glutamine uptake in primary cultures of astrocytes. J Neurochem (1979) 0.95
Utilization of glutamine and of TCA cycle constituents as precursors for transmitter glutamate and GABA. Dev Neurosci (1993) 0.95
Ionic mechanisms in glutamate-induced astrocyte swelling: role of K+ influx. J Neurosci Res (1998) 0.95
GABA uptake inhibitors: relevance to antiepileptic drug research. Epilepsy Res (1987) 0.95
Uptake and metabolism of glutamate in astrocytes cultured from dissociated mouse brain hemispheres. J Neurochem (1977) 0.95
Comparison of lactate and glucose metabolism in cultured neocortical neurons and astrocytes using 13C-NMR spectroscopy. Dev Neurosci (1998) 0.95
Excitatory amino acid-induced release of 3H-GABA from cultured mouse cerebral cortex interneurons. J Neurosci (1987) 0.95
Volume regulation in astrocytes: a role for taurine as an osmoeffector. J Neurosci Res (1988) 0.94
Piperidine-4-sulphonic acid, a new specific GABA agonist. J Neurochem (1980) 0.94
Evaluation of the importance of transamination versus deamination in astrocytic metabolism of [U-13C]glutamate. Glia (1996) 0.93
Effects of valproate, vigabatrin and aminooxyacetic acid on release of endogenous and exogenous GABA from cultured neurons. Epilepsy Res (1989) 0.93
NMR spectroscopic studies of 13C acetate and 13C glucose metabolism in neocortical astrocytes: evidence for mitochondrial heterogeneity. Dev Neurosci (1993) 0.93
Evidence that aspartate aminotransferase activity and ketodicarboxylate carrier function are essential for biosynthesis of transmitter glutamate. J Neurochem (1988) 0.93
Metabolism of [U-13C]glutamate in astrocytes studied by 13C NMR spectroscopy: incorporation of more label into lactate than into glutamine demonstrates the importance of the tricarboxylic acid cycle. J Neurochem (1993) 0.93
Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice. Epilepsy Res (2011) 0.92
Characterization of glutamate-induced formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cultured neocortical neurons. J Neurochem (1997) 0.92
Glutamate receptor agonists up-regulate glutamate transporter GLAST in astrocytes. Neuroreport (1996) 0.92
Glutaminase in neurons and astrocytes cultured from mouse brain: kinetic properties and effects of phosphate, glutamate, and ammonia. Neurochem Res (1988) 0.92
Hippocampal stimulation produces neuronal death in the immature brain. Neuroscience (1998) 0.92
Metabolic differences between primary cultures of astrocytes and neurons from cerebellum and cerebral cortex. Effects of fluorocitrate. Neurochem Res (1995) 0.92
Characterization of a chemical anoxia model in cerebellar granule neurons using sodium azide: protection by nifedipine and MK-801. J Neurosci Res (1996) 0.91
Volume-sensitive release of taurine from cultured astrocytes: properties and mechanism. Glia (1990) 0.91
Metabolism of lactate in cultured GABAergic neurons studied by 13C nuclear magnetic resonance spectroscopy. J Cereb Blood Flow Metab (1998) 0.91
Kinetic characteristics of the glutamate uptake into normal astrocytes in cultures. Neurochem Res (1978) 0.91
A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type A receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics. Mol Pharmacol (2000) 0.91
Cultured neurons as model systems for biochemical and pharmacological studies on receptors for neurotransmitter amino acids. Dev Neurosci (1985) 0.90
Elucidation of the quantitative significance of pyruvate carboxylation in cultured cerebellar neurons and astrocytes. J Neurosci Res (2001) 0.90
Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neurons. Proc Natl Acad Sci U S A (1992) 0.90
Comparison of effects of DL-threo-beta-benzyloxyaspartate (DL-TBOA) and L-trans-pyrrolidine-2,4-dicarboxylate (t-2,4-PDC) on uptake and release of [3h]D-aspartate in astrocytes and glutamatergic neurons. Neurochem Res (2001) 0.89
Role of aspartate aminotransferase and mitochondrial dicarboxylate transport for release of endogenously and exogenously supplied neurotransmitter in glutamatergic neurons. Neurochem Res (1989) 0.89
Compartmentation of TCA cycle metabolism in cultured neocortical neurons revealed by 13C MR spectroscopy. Neurochem Int (2000) 0.89
Ion and energy metabolism of the brain at the cellular level. Int Rev Neurobiol (1975) 0.89
Differential effect of gamma-vinyl GABA and valproate on GABA-transaminase from cultured neurones and astrocytes. Neuropharmacology (1986) 0.88
Characterization of microwell cultures of dissociated brain tissue for studies of cell-cell interactions. J Neurosci Res (1997) 0.88
Distribution of mitochondria within Müller cells--I. Correlation with retinal vascularization in different mammalian species. J Neurocytol (1998) 0.88
Effects of gamma-aminobutyric acid (GABA) on synaptogenesis and synaptic function. Perspect Dev Neurobiol (1998) 0.87
Glutamate receptor activation in cultured cerebellar granule cells increases cytosolic free Ca2+ by mobilization of cellular Ca2+ and activation of Ca2+ influx. Exp Brain Res (1989) 0.87
Synthesis of vesicular GABA from glutamine involves TCA cycle metabolism in neocortical neurons. J Neurosci Res (1999) 0.87
The effects of isofagomine, a potent glycogen phosphorylase inhibitor, on glycogen metabolism in cultured mouse cortical astrocytes. Neurochem Int (2000) 0.87
Properties of phosphate activated glutaminase in astrocytes cultured from mouse brain. Neurochem Res (1982) 0.87
Uptake, release, and metabolism of citrate in neurons and astrocytes in primary cultures. J Neurochem (1994) 0.87
Transport of L-[3H]arginine in cultured neurons: characteristics and inhibition by nitric oxide synthase inhibitors. J Neurochem (1993) 0.86
Pharmacologically distinct glutamate receptors on cerebellar granule cells. Life Sci (1986) 0.86
Metabolic fate of [14C]-glutamine in mouse cerebral neurons in primary cultures. J Neurosci Res (1984) 0.86
Identification and function of glycine receptors in cultured cerebellar granule cells. J Neurochem (1994) 0.86
Depolarization by K+ and glutamate activates different neurotransmitter release mechanisms in GABAergic neurons: vesicular versus non-vesicular release of GABA. Neuroscience (1993) 0.86
Identification of amino acid residues in GluR1 responsible for ligand binding and desensitization. J Neurosci (2001) 0.86
Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex. J Neurosci Res (2001) 0.86
Kainic acid-induced seizures and brain damage in the rat: role of calcium homeostasis. J Neurosci Res (1995) 0.86
Receptor expression in primary cultures of neurons or astrocytes. Prog Neuropsychopharmacol Biol Psychiatry (1984) 0.86
Excitatory amino acid-mediated cytotoxicity and calcium homeostasis in cultured neurons. J Neurochem (1993) 0.86
Immunochemical studies of brain glutamate decarboxylase and GABA-transaminase of six inbred strains of mice. Brain Res (1974) 0.85
Neuronal-astrocytic and cytosolic-mitochondrial metabolite trafficking during brain activation, hyperammonemia and energy deprivation. Neurochem Int (2000) 0.85
Some immunochemical properties and species specificity of GABA-alpha-ketoglutarate transaminase from mouse brain. Brain Res (1974) 0.85
Metabolic distinction between vesicular and cytosolic GABA in cultured GABAergic neurons using 13C magnetic resonance spectroscopy. J Neurosci Res (2001) 0.85
Action of bicyclic isoxazole GABA analogues on GABA transporters and its relation to anticonvulsant activity. Eur J Pharmacol (1999) 0.85
Hyposmolarity-activated fluxes of taurine in astrocytes are mediated by diffusion. Neurosci Lett (1991) 0.85
Differential effects of nipecotic acid and 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol on extracellular gamma-aminobutyrate levels in rat thalamus. Eur J Pharmacol (1997) 0.85
Pharmacological properties of homomeric and heteromeric GluR1o and GluR3o receptors. Eur J Pharmacol (1998) 0.84
Selection of a pure cerebellar granule cell culture by kainate treatment. Neurochem Res (1989) 0.84
Immunocytochemical investigation of L-glutamic acid decarboxylase in the rat hippocampal formation: the influence of transient cerebral ischemia. J Comp Neurol (1989) 0.84
Glutamate-induced increase in intracellular Ca2+ in cerebral cortex neurons is transient in immature cells but permanent in mature cells. J Neurochem (1989) 0.84
Kinetic characterization of inhibition of gamma-aminobutyric acid uptake into cultured neurons and astrocytes by 4,4-diphenyl-3-butenyl derivatives of nipecotic acid and guvacine. J Neurochem (1988) 0.84
Uptake of GABA and nipecotic acid in astrocytes and neurons in primary cultures: changes in the sodium coupling ratio during differentiation. J Neurosci Res (1986) 0.84
First direct demonstration of preferential release of citrate from astrocytes using [13C]NMR spectroscopy of cultured neurons and astrocytes. Neurosci Lett (1991) 0.84