Published in J Infect Dis on June 01, 1981
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25 years of interferon-based treatment of chronic hepatitis C: an epoch coming to an end. Nat Rev Immunol (2013) 1.35
Antiviral treatment of chronic hepatitis B virus infection: pharmacokinetics and side effects of interferon and adenine arabinoside alone and in combination. Antimicrob Agents Chemother (1982) 1.00
Selecting binding and complement-mediated lysis of human hepatoma cells (PLC/PRF/5) in culture by monoclonal antibodies to hepatitis B surface antigen. Proc Natl Acad Sci U S A (1982) 0.99
Randomised controlled trial of adenine arabinoside 5'-monophosphate (ARA-AMP) in chronic hepatitis B virus infection. Gut (1985) 0.98
Activities of arabinosyladenine monophosphate and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against ground squirrel hepatitis virus in vivo as determined by reduction in serum virion-associated DNA polymerase. Antimicrob Agents Chemother (1985) 0.89
Randomised placebo controlled trials in HIV infection: to be or not to be? Genitourin Med (1989) 0.80
Psychosocial impact of chronic infection with hepatitis B virus on British patients. Genitourin Med (1985) 0.80
Inactivation of S-adenosylhomocysteine hydrolase during adenine arabinoside therapy. J Clin Invest (1982) 0.77
Randomised controlled trial of lymphoblastoid interferon for chronic active hepatitis B. Gut (1987) 0.76
Effect of adenine arabinoside and alpha-interferon in patients with HBeAg-positive chronic active hepatitis. Korean J Intern Med (1990) 0.75
Preliminary trial of recombinant fibroblast interferon in chronic hepatitis B virus infection. Antimicrob Agents Chemother (1986) 0.75
Advances in interferon research - Medical Staff Conference. West J Med (1982) 0.75
Antiviral treatment in chronic infection with hepatitis B virus. Br Med J (Clin Res Ed) (1986) 0.75
The effect of recombinant interferon-alpha on lymphocyte subpopulations and HLA-DR expression on liver tissue of HBV-positive individuals. Clin Exp Immunol (1990) 0.75
Antiviral treatment of chronic hepatitis B virus infection. J R Soc Med (1984) 0.75
DNA polymerase associated with human hepatitis B antigen. J Virol (1973) 10.71
The mass and oxygen capacity of the blood in man. J Physiol (1900) 10.55
A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 cell counts from 200 to 500 per cubic millimeter. AIDS Clinical Trials Group Study 175 Study Team. N Engl J Med (1996) 7.60
DNA of a human hepatitis B virus candidate. J Virol (1974) 5.90
Distinct dendritic cell subsets differentially regulate the class of immune response in vivo. Proc Natl Acad Sci U S A (1999) 5.66
A virus in Beechey ground squirrels that is related to hepatitis B virus of humans. Proc Natl Acad Sci U S A (1980) 5.63
Crystal structure of core streptavidin determined from multiwavelength anomalous diffraction of synchrotron radiation. Proc Natl Acad Sci U S A (1989) 5.57
Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays. Nat Med (1996) 5.35
Hepatitis B virus contains protein attached to the 5' terminus of its complete DNA strand. Cell (1980) 5.21
The nucleic acid of the Bryan strain of Rous sarcoma virus: purification of the virus and isolation of the nucleic acid. Proc Natl Acad Sci U S A (1965) 4.95
Isolation of the nucleic acid of Newcastle disease virus (NDV). Proc Natl Acad Sci U S A (1965) 4.83
The Absorption of Oxygen by the Lungs. J Physiol (1897) 4.50
Treatment of human immunodeficiency virus infection with saquinavir, zidovudine, and zalcitabine. AIDS Clinical Trials Group. N Engl J Med (1996) 4.43
Recombinant interferon-gamma increases HLA-DR synthesis and expression. J Immunol (1983) 4.09
The relation of virologic and immunologic markers to clinical outcomes after nucleoside therapy in HIV-infected adults with 200 to 500 CD4 cells per cubic millimeter. AIDS Clinical Trials Group Study 175 Virology Study Team. N Engl J Med (1996) 4.03
Structure of hepatitis B Dane particle DNA and nature of the endogenous DNA polymerase reaction. J Virol (1977) 4.02
Proteins of Rous sarcoma virus. Virology (1968) 3.84
Rapid detection and quantitation of human cytomegalovirus in urine through DNA hybridization. N Engl J Med (1983) 3.83
A prospective study of advance directives for life-sustaining care. N Engl J Med (1991) 3.72
Interferon: protection of cells infected with an intracellular protozoan (Toxoplasma gondii). Science (1968) 3.65
Cloning and endonuclease mapping of the hepatitis B viral genome. Nature (1979) 3.62
Structure of hepatitis B Dane particle DNA before and after the Dane particle DNA polymerase reaction. J Virol (1977) 3.57
Phenotypic and functional characterization of mice that lack the type I receptor for IL-1. J Immunol (1997) 3.56
Multiple concurrent reverse transcriptase and protease mutations and multidrug resistance of HIV-1 isolates from heavily treated patients. Ann Intern Med (1998) 3.55
DNA polymerase in the core of the human hepatitis B virus candidate. J Virol (1974) 3.44
The Oxygen Tension of Arterial Blood. J Physiol (1896) 3.40
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The effect of high-dose saquinavir on viral load and CD4+ T-cell counts in HIV-infected patients. Ann Intern Med (1996) 3.35
The course of patients after variceal hemorrhage. Gastroenterology (1981) 3.33
Inhibition of human immunodeficiency virus gene amplification by heparin. J Clin Microbiol (1991) 3.32
A protein catalytic framework with an N-terminal nucleophile is capable of self-activation. Nature (1995) 3.30
The pathological effects due to increase of oxygen tension in the air breathed. J Physiol (1899) 3.28
DNA in uninfected and virus-infected cells complementary to avian tumor virus RNA. Proc Natl Acad Sci U S A (1971) 3.25
Stages in the nuclear association of the herpes simplex virus transcriptional activator protein ICP4. J Virol (1987) 3.24
Hepatitis B infection in physicians. Results of a nationwide seroepidemiologic survey. JAMA (1978) 3.24
Nucleic acid and proteins isolated from the Rauscher mouse leukemia virus (MLV). Proc Natl Acad Sci U S A (1966) 3.23
Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy. J Virol (1996) 3.21
Concerning the mechanism of action of interferon. Proc Natl Acad Sci U S A (1966) 3.15
Replication of Sendai virus. I. Comparison of the viral RNA and virus-specific RNA synthesis with Newcastle disease virus. Virology (1968) 3.11
Inhibition of respiratory virus infection by locally applied interferon. Lancet (1973) 3.02
Frequency of class I HLA-restricted anti-HIV CD8+ T cells in individuals receiving highly active antiretroviral therapy (HAART). J Immunol (1999) 2.89
A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors. J Clin Invest (1998) 2.88
On-line computer quality control of antibiotic-sensitivity testing. N Engl J Med (1970) 2.88
Detection and quantification of human immunodeficiency virus RNA in patient serum by use of the polymerase chain reaction. J Infect Dis (1991) 2.86
On the structure and replication of influenza virus. J Mol Biol (1967) 2.84
Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis. N Engl J Med (1976) 2.80
Structure of myohemerythrin in the azidomet state at 1.7/1.3 A resolution. J Mol Biol (1987) 2.79
Inhibition of TRIC agents by virus-induced interferon. Proc Soc Exp Biol Med (1966) 2.78
Isolation and characterization of proteins from Rous sarcoma virus. Virology (1971) 2.66
Lymphocyte interferon production and transformation after Herpes simplex infections in humans. J Immunol (1974) 2.64
Physical properties of human interferon prepared in vitro and in vivo. Virology (1966) 2.62
Hepatitis B viral DNA molecules have cohesive ends. J Virol (1979) 2.61
Variceal hemorrhage: a critical evaluation of survival analysis. Gastroenterology (1982) 2.60
DNA polymerase in defective Rous sarcoma virus. Virology (1971) 2.56
The nucleic acid from avian myeloblastosis virus compared with the RNA from the Bryan strain of Rous sarcoma virus. Proc Natl Acad Sci U S A (1965) 2.52
Immunologic tolerance to renal allografts after bone marrow transplants from the same donors. Ann Intern Med (1991) 2.46
High degree of interlaboratory reproducibility of human immunodeficiency virus type 1 protease and reverse transcriptase sequencing of plasma samples from heavily treated patients. J Clin Microbiol (2001) 2.45
Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures. Blood (2000) 2.45
Recombinant soluble CD4 therapy in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. A phase I-II escalating dosage trial. Ann Intern Med (1990) 2.40
Paracentric inversions in humans: a review of 446 paracentric inversions with presentation of 120 new cases. Am J Med Genet (1995) 2.39
HIV-1 genotypic resistance patterns predict response to saquinavir-ritonavir therapy in patients in whom previous protease inhibitor therapy had failed. Ann Intern Med (1999) 2.36
Murine monoclonal antibody to a single protein neutralizes the infectivity of human cytomegalovirus. Proc Natl Acad Sci U S A (1984) 2.32
The genome of hepatitis B virus. Annu Rev Microbiol (1977) 2.31
Spirochetes in the aqueous humor in seronegative ocular syphilis. Persistence after penicillin therapy. Arch Ophthalmol (1967) 2.30
Virus-specific IgG and IgM antibodies in normal and immunocompromised subjects infected with cytomegalovirus. J Infect Dis (1982) 2.29
Evolution of recurrent herpes simplex lesions. An immunohistologic study. J Clin Invest (1985) 2.28
A mutation in human immunodeficiency virus reverse transcriptase and decline in CD4 lymphocyte numbers in long-term zidovudine recipients. J Infect Dis (1993) 2.28
DNA and DNA polymerase in the core of the Dane particle of hepatitis B. Am J Med Sci (1976) 2.24
Common evolutionary origin of hepatitis B virus and retroviruses. Proc Natl Acad Sci U S A (1986) 2.20
Structural relationships between the surface antigens of ground squirrel hepatitis virus and human hepatitis B virus. J Virol (1980) 2.20
Tumor virus RNA's. Proc Natl Acad Sci U S A (1967) 2.18
Motility in Pseudomonas fluorescens with special reference to survival advantage and negative chemotaxis. Life Sci (1968) 2.17
ON A CASE OF SEPTICAEMIA TREATED BY INTRAVENOUS INJECTION OF EUSOL. Br Med J (1915) 2.16
Interferon inducers in vitro: difference in sensitivity to inhbitiros of RNA and protein synthesis. Science (1968) 2.16
Self-annealing of subgroup 2 myxovirus RNAs. Nature (1970) 2.16
Restriction endonuclease cleavage map and location of unique features of the DNA of hepatitis B virus, subtype adw2. Proc Natl Acad Sci U S A (1979) 2.15
Spontaneous regression of primary malignant melanomas with regional metastases. Cancer (1965) 2.15
Structure of a dehydratase-isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site. Structure (1996) 2.14
Human cytomegalovirus strain Towne glycoprotein B is processed by proteolytic cleavage. Virology (1988) 2.14
Alteplase versus heparin in acute pulmonary embolism: randomised trial assessing right-ventricular function and pulmonary perfusion. Lancet (1993) 2.12
The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families. Nat Struct Biol (1996) 2.11
Cellular immunity and herpesvirus infections in cardiac-transplant patients. N Engl J Med (1977) 2.09
Characteristics of immune interferon produced by human lymphocyte cultures compared to other human interferons. J Immunol (1975) 2.09
A new modification of the Krajian silver stain for Treponema pallidum. Br J Vener Dis (1969) 2.09
Measles in adults. An unforeseen consequence of immunization? JAMA (1976) 2.08
Using the Internet for psychological research: personality testing on the World Wide Web. Br J Psychol (1999) 2.06
Patient compliance and drug failure in protease inhibitor monotherapy. JAMA (1996) 2.06
Gastroduodenal mucosa and dyspeptic symptoms in arthritic patients during chronic nonsteroidal anti-inflammatory drug use. Am J Gastroenterol (1987) 2.05
Sclerotherapy for actively bleeding esophageal varices in male alcoholics with cirrhosis. Veterans Affairs Cooperative Variceal Sclerotherapy Group. Gastrointest Endosc (1997) 2.05
Human leukocyte interferon for the treatment of herpes zoster in patients with cancer. N Engl J Med (1978) 2.04
Direct phase determination based on anomalous scattering. Methods Enzymol (1985) 2.02
State of hepatitis B viral DNA in a human hepatoma cell line. J Virol (1980) 2.02