Published in Proc Natl Acad Sci U S A on June 01, 1981
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol Cell Biol (1985) 25.52
The Human Gene Mutation Database: 2008 update. Genome Med (2009) 11.72
Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli. Antimicrob Agents Chemother (1990) 11.71
The 65-kilodalton antigen of Mycobacterium tuberculosis. J Bacteriol (1987) 9.50
'DNA Strider': a 'C' program for the fast analysis of DNA and protein sequences on the Apple Macintosh family of computers. Nucleic Acids Res (1988) 9.48
Functional expression of a probable Arabidopsis thaliana potassium channel in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1992) 6.27
Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: prediction of antigenic epitopes in conserved and variable regions. J Virol (1987) 6.20
Quinolone resistance-determining region in the DNA gyrase gyrB gene of Escherichia coli. Antimicrob Agents Chemother (1991) 6.19
Diversity of Chlamydia trachomatis major outer membrane protein genes. J Bacteriol (1987) 6.16
Nucleotide and deduced amino acid sequences for the four variable domains of the major outer membrane proteins of the 15 Chlamydia trachomatis serovars. Infect Immun (1989) 5.75
Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide. J Virol (1985) 5.73
Shuttle cloning and nucleotide sequences of Helicobacter pylori genes responsible for urease activity. J Bacteriol (1991) 5.72
fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen. Mol Cell Biol (1988) 5.12
Ab initio modeling of small proteins by iterative TASSER simulations. BMC Biol (2007) 5.07
T-cell antigenic sites tend to be amphipathic structures. Proc Natl Acad Sci U S A (1985) 5.05
Cloning and structural analyses of hepatitis B virus DNAs, subtype adr. Nucleic Acids Res (1983) 4.94
Mapping of sequences required for mouse neurovirulence of poliovirus type 2 Lansing. J Virol (1986) 4.91
Transcription, organization, and sequence of an auxin-regulated gene cluster in soybean. Plant Cell (1989) 4.79
TOUCHSTONE II: a new approach to ab initio protein structure prediction. Biophys J (2003) 4.62
Improved method for predicting linear B-cell epitopes. Immunome Res (2006) 4.32
Induction of anti-HIV neutralizing antibodies by synthetic peptides. EMBO J (1986) 4.32
Dengue virus structural differences that correlate with pathogenesis. J Virol (1999) 4.26
Characterization of the virA locus of Agrobacterium tumefaciens: a transcriptional regulator and host range determinant. EMBO J (1987) 4.22
Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells. EMBO J (1989) 4.10
Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. Proc Natl Acad Sci U S A (1987) 3.99
Cloning and expression of the Mycobacterium bovis BCG gene for extracellular alpha antigen. J Bacteriol (1988) 3.97
Nucleotide sequence of the G protein gene of human respiratory syncytial virus reveals an unusual type of viral membrane protein. Proc Natl Acad Sci U S A (1985) 3.93
The complete nucleotide sequence of a common cold virus: human rhinovirus 14. Nucleic Acids Res (1984) 3.85
Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties. Proc Natl Acad Sci U S A (1988) 3.83
Sequence variability of three alleles of the self-incompatibility gene of Nicotiana alata. Plant Cell (1989) 3.81
Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product. Mol Cell Biol (1988) 3.74
Nucleotide sequence of the papA gene encoding the Pap pilus subunit of human uropathogenic Escherichia coli. J Bacteriol (1984) 3.73
Human rhinovirus 2: complete nucleotide sequence and proteolytic processing signals in the capsid protein region. Nucleic Acids Res (1985) 3.69
Characterization of invasion plasmid antigen genes (ipaBCD) from Shigella flexneri. Proc Natl Acad Sci U S A (1988) 3.65
High-resolution mapping of serovar-specific and common antigenic determinants of the major outer membrane protein of Chlamydia trachomatis. J Exp Med (1988) 3.55
Localization and synthesis of an antigenic determinant of herpes simplex virus glycoprotein D that stimulates the production of neutralizing antibody. J Virol (1984) 3.53
LcrD, a membrane-bound regulator of the Yersinia pestis low-calcium response. J Bacteriol (1991) 3.43
Structure and mapping of antigenic domains of protein antigen b, a 38,000-molecular-weight protein of Mycobacterium tuberculosis. Infect Immun (1989) 3.43
Polymorphism and divergence in the Mst26A male accessory gland gene region in Drosophila. Genetics (1992) 3.43
Nucleotide sequence analysis of the proviral genome of avian myelocytomatosis virus (MC29). Proc Natl Acad Sci U S A (1983) 3.43
Structural similarity among Escherichia coli FtsW and RodA proteins and Bacillus subtilis SpoVE protein, which function in cell division, cell elongation, and spore formation, respectively. J Bacteriol (1989) 3.41
Nucleotide sequence of the envelope gene of Friend murine leukemia virus. J Virol (1983) 3.41
MUSTER: Improving protein sequence profile-profile alignments by using multiple sources of structure information. Proteins (2008) 3.38
DNA sequence of the viral and cellular src gene of chickens. 1. Complete nucleotide sequence of an EcoRI fragment of recovered avian sarcoma virus which codes for gp37 and pp60src. J Virol (1982) 3.35
Gonococcal pili. Primary structure and receptor binding domain. J Exp Med (1984) 3.32
Antibodies against a preselected peptide recognize and neutralize foot and mouth disease virus. EMBO J (1982) 3.32
Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay. J Clin Invest (1994) 3.30
DNA sequence of mip, a Legionella pneumophila gene associated with macrophage infectivity. Infect Immun (1989) 3.29
Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV. J Virol (1991) 3.28
Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis. EMBO J (1990) 3.27
Evolution of the primate lentiviruses: evidence from vpx and vpr. EMBO J (1992) 3.25
Dualistic nature of adhesive protein function: fibronectin and its biologically active peptide fragments can autoinhibit fibronectin function. J Cell Biol (1984) 3.18
Molecular cloning and the nucleotide sequence of the Mr 28 000 crystal protein gene of Bacillus thuringiensis subsp. israelensis. Nucleic Acids Res (1985) 3.16
Primary structure of the 175K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion. J Cell Biol (1990) 3.11
Human epidermal growth factor precursor: cDNA sequence, expression in vitro and gene organization. Nucleic Acids Res (1986) 3.11
Two related Epstein-Barr virus membrane proteins are encoded by separate genes. J Virol (1989) 3.09
Prediction of residues in discontinuous B-cell epitopes using protein 3D structures. Protein Sci (2006) 3.06
Envelope and long terminal repeat sequences of a cloned infectious NZB xenotropic murine leukemia virus. J Virol (1985) 3.06
Cloning and sequence analysis of cytadhesin P1 gene from Mycoplasma pneumoniae. Infect Immun (1987) 3.05
Nucleotide and deduced amino acid sequences of Torpedo californica acetylcholine receptor gamma subunit. Proc Natl Acad Sci U S A (1983) 3.01
Fine mapping of an immunodominant domain in the transmembrane glycoprotein of human immunodeficiency virus. J Virol (1987) 2.97
Molecular characterization and nucleic acid sequence of an avirulence gene from race 6 of Pseudomonas syringae pv. glycinea. J Bacteriol (1987) 2.95
Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growth. J Virol (1993) 2.92
Hypothesis about the function of membrane-buried proline residues in transport proteins. Proc Natl Acad Sci U S A (1986) 2.90
Nucleotide sequence of avian sarcoma virus UR2 and comparison of its transforming gene with other members of the tyrosine protein kinase oncogene family. J Virol (1985) 2.88
Evolution of influenza A and B viruses: conservation of structural features in the hemagglutinin genes. Proc Natl Acad Sci U S A (1982) 2.86
Structure of genes narL and narX of the nar (nitrate reductase) locus in Escherichia coli K-12. J Bacteriol (1989) 2.83
Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins. J Exp Med (1988) 2.75
TRK1 and TRK2 encode structurally related K+ transporters in Saccharomyces cerevisiae. Mol Cell Biol (1991) 2.74
Molecular basis for surface antigen size polymorphisms and conservation of a neutralization-sensitive epitope in Anaplasma marginale. Proc Natl Acad Sci U S A (1990) 2.74
Strain-specific and common epitopes of gonococcal pili. J Exp Med (1984) 2.72
Location of the major antigenic sites involved in rotavirus serotype-specific neutralization. Proc Natl Acad Sci U S A (1986) 2.71
Localization of epitopes of herpes simplex virus type 1 glycoprotein D. J Virol (1985) 2.71
Poxvirus orthologous clusters: toward defining the minimum essential poxvirus genome. J Virol (2003) 2.70
Nucleotide and amino acid sequence coding for polypeptides of foot-and-mouth disease virus type A12. J Virol (1985) 2.65
Yeast Sec23p acts in the cytoplasm to promote protein transport from the endoplasmic reticulum to the Golgi complex in vivo and in vitro. EMBO J (1989) 2.64
Localization and fine structure of a vaccinia virus gene encoding an envelope antigen. J Virol (1986) 2.64
Complete nucleotide sequence of the infectious cloned DNA components of tomato golden mosaic virus: potential coding regions and regulatory sequences. EMBO J (1984) 2.63
Identification of an alternatively spliced site in human plasma fibronectin that mediates cell type-specific adhesion. J Cell Biol (1986) 2.63
Tetanus toxin: primary structure, expression in E. coli, and homology with botulinum toxins. EMBO J (1986) 2.62
Nucleotide sequence of a complete mouse intracisternal A-particle genome: relationship to known aspects of particle assembly and function. J Virol (1987) 2.57
Detection of antibodies to human T-lymphotropic virus type III by using a synthetic peptide of 21 amino acid residues corresponding to a highly antigenic segment of gp41 envelope protein. Proc Natl Acad Sci U S A (1986) 2.54
The plant ferredoxin precursor: nucleotide sequence of a full length cDNA clone. Nucleic Acids Res (1985) 2.54
Mechanism of postsegregational killing by the hok gene product of the parB system of plasmid R1 and its homology with the relF gene product of the E. coli relB operon. EMBO J (1986) 2.54
Comparative studies of the amino acid and nucleotide sequences of pilin derived from Pseudomonas aeruginosa PAK and PAO. J Bacteriol (1985) 2.53
Hepatitis B virus vaccine: identification of HBsAg/a and HBsAg/d but not HBsAg/y subtype antigenic determinants on a synthetic immunogenic peptide. Proc Natl Acad Sci U S A (1982) 2.52
Structure and expression of the herpes simplex virus type 2 glycoprotein gB gene. J Virol (1987) 2.52
Nucleotide sequence of the plasminogen activator gene of Yersinia pestis: relationship to ompT of Escherichia coli and gene E of Salmonella typhimurium. Infect Immun (1989) 2.45
Primary structure and gene organization of human hepatitis A virus. Proc Natl Acad Sci U S A (1985) 2.43
Mapping and sequence of the gene for the pseudorabies virus glycoprotein which accumulates in the medium of infected cells. J Virol (1985) 2.43
Molecular structure of ilvIH and its evolutionary relationship to ilvG in Escherichia coli K12. Nucleic Acids Res (1983) 2.39
The yopM gene of Yersinia pestis encodes a released protein having homology with the human platelet surface protein GPIb alpha. J Bacteriol (1989) 2.37
Localization of the adenovirus E1Aa protein, a positive-acting transcriptional factor, in infected cells infected cells. Mol Cell Biol (1983) 2.36
Nucleotide sequences of a feline leukemia virus subgroup A envelope gene and long terminal repeat and evidence for the recombinational origin of subgroup B viruses. J Virol (1986) 2.34
Vaccinia virus 19-kilodalton protein: relationship to several mammalian proteins, including two growth factors. Proc Natl Acad Sci U S A (1984) 2.34
Identification of the pcaRKF gene cluster from Pseudomonas putida: involvement in chemotaxis, biodegradation, and transport of 4-hydroxybenzoate. J Bacteriol (1994) 2.33
Using support vector machine combined with auto covariance to predict protein-protein interactions from protein sequences. Nucleic Acids Res (2008) 2.29
Immunoenzymatic detection of expressed gene fragments cloned in the lac Z gene of E. coli. EMBO J (1982) 2.29
Genomic cloning and complete sequence analysis of a highly divergent African human immunodeficiency virus isolate. J Virol (1994) 2.29
Transmembrane helix predictions revisited. Protein Sci (2002) 2.28
Complete structure of the hemagglutinin gene from the human influenza A/Victoria/3/75 (H3N2) strain as determined from cloned DNA. Cell (1980) 14.28
Conformational parameters for amino acids in helical, beta-sheet, and random coil regions calculated from proteins. Biochemistry (1974) 12.07
Nucleotide sequence of cdna coding for Semliki Forest virus membrane glycoproteins. Nature (1980) 8.07
The solubility of amino acids and two glycine peptides in aqueous ethanol and dioxane solutions. Establishment of a hydrophobicity scale. J Biol Chem (1971) 8.06
Complete nucleotide sequence of an influenza virus haemagglutinin gene from cloned DNA. Nature (1979) 7.15
A simplified representation of protein conformations for rapid simulation of protein folding. J Mol Biol (1976) 7.06
Nucleotide sequence of the gene coding for the major protein of hepatitis B virus surface antigen. Nature (1979) 6.10
Amino acid sequence homology between cholera toxin and Escherichia coli heat-labile toxin. Nature (1980) 6.04
Human leukocyte interferon produced by E. coli is biologically active. Nature (1980) 5.86
Nucleotide sequence of the bacterial transposon Tn1681 encoding a heat-stable (ST) toxin and its identification in enterotoxigenic Escherichia coli strains. Proc Natl Acad Sci U S A (1980) 5.46
Antigenic drift between the haemagglutinin of the Hong Kong influenza strains A/Aichi/2/68 and A/Victoria/3/75. Nature (1980) 5.25
Antigenic structure of myoglobin: the complete immunochemical anatomy of a protein and conclusions relating to antigenic structures of proteins. Immunochemistry (1975) 4.90
Isolation and structure of a human fibroblast interferon gene. Nature (1980) 4.16
Human leukocyte and fibroblast interferons are structurally related. Nature (1980) 3.57
Primary structure of protective antigens of type 24 streptococcal M protein. J Biol Chem (1980) 3.39
Hydrophobic basis of packing in globular proteins. Proc Natl Acad Sci U S A (1980) 3.19
Complete amino acid sequence of a papain-solubilized human histocompatibility antigen, HLA-B7. 2. Sequence determination and search for homologies. Biochemistry (1979) 2.71
Primary structure of cholera toxin beta-chain: a glycoprotein hormone analog? Science (1977) 2.66
Amino acid substitution and the antigenicity of globular proteins. Adv Immunol (1975) 2.32
The precise and entire antigenic structure of native lysozyme. Biochem J (1978) 2.15
Status of empirical methods for the prediction of protein backbone topography. Biochemistry (1976) 2.12
The detection of five antigenically reactive regions in the soybean leghemoglobin a molecule. Immunochemistry (1978) 2.09
Antiviral response elicited by a completely synthetic antigen with built-in adjuvanticity. Proc Natl Acad Sci U S A (1980) 2.07
Prediction and conformation by synthesis of two antigenic sites in human haemoglobin by extrapolation from the known antigenic structure of sperm-whale myoglobin. Biochem J (1977) 1.99
The amino acid sequence of ragweed pollen allergen Ra5. Biochemistry (1975) 1.85
Topographic antigenic determinants on cytochrome c. Immunoadsorbent separation of the rabbit antibody populations directed against horse cytochrome. J Biol Chem (1979) 1.78
Immunochemical studies of tobacco mosaic virus--III. Demonstration of five antigenic regions in the protein sub-unit. Mol Immunol (1979) 1.78
[EXPERIMENTS ON THE DETERMINATION OF THE SEROLOGICALLY DETERMINANT GROUPS OF TOBACCO MOSAIC VIRUS]. Z Naturforsch B (1963) 1.75
Immunological studies on the major haptenic peptides from performic acid oxidized ferredoxin from Clostridium pasteurianum. Biochemistry (1971) 1.73
Amino acid sequence of ragweed allergen Ra3. Biochemistry (1980) 1.71
An encephalitogenic region for rabbits. Immunochemistry (1978) 1.63
Peptides and autoimmune disease. Adv Exp Med Biol (1978) 1.58
Separation of dansyl-amino acids by polyamide layer chromatography. Biochim Biophys Acta (1967) 12.65
Detection and characterization of high affinity plasma membrane receptors for human interleukin 1. J Exp Med (1985) 3.00
The cell surface receptors for interleukin-1 alpha and interleukin-1 beta are identical. Nature (1987) 2.68
Hepatitis B virus vaccine: identification of HBsAg/a and HBsAg/d but not HBsAg/y subtype antigenic determinants on a synthetic immunogenic peptide. Proc Natl Acad Sci U S A (1982) 2.52
Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor. J Biol Chem (1988) 2.46
A computer program for predicting protein antigenic determinants. Mol Immunol (1983) 2.09
A calcium-dependent antibody for identification and purification of recombinant proteins. Biotechniques (1989) 1.86
Protein surface analysis. Methods for identifying antigenic determinants and other interaction sites. J Immunol Methods (1986) 1.81
Human interleukin 1. Purification to homogeneity. J Exp Med (1985) 1.72
Cell-free synthesis and segregation of beta 2-microglobulin. Proc Natl Acad Sci U S A (1979) 1.39
Favin versus concanavalin A: Circularly permuted amino acid sequences. Proc Natl Acad Sci U S A (1979) 1.33
N-terminal disulphide knot of human fibrinogen. Nature (1968) 1.33
Localization of human mononuclear cell interleukin 1. J Immunol (1987) 1.33
Evidence for localization of polymerization sites in fibrinogen. J Biol Chem (1974) 1.27
A synthetic peptide with hepatitis B surface antigen reactivity. Mol Immunol (1981) 1.22
Structure of the heavy chain of the H-2Kk histocompatibility antigen. Proc Natl Acad Sci U S A (1980) 1.14
An aid to the treatment of supracondylar fracture of the humerus: brief report. J Bone Joint Surg Br (1989) 1.14
A pre-aspartate-specific protease from human leukocytes that cleaves pro-interleukin-1 beta. J Biol Chem (1989) 1.13
The chemical characterization of favin, a lectin isolated from Vicia faba. J Biol Chem (1979) 1.04
Immunogenicity of a synthetic HBsAg peptide: enhancement by conjugation to a fatty acid carrier. Mol Immunol (1984) 1.03
Amino acid sequence and variant forms of favin, a lectin from Vicia faba. J Biol Chem (1982) 0.98
Antibody against serum-hepatitis antigen. Prevalence and potential use as immune serum globulin in prevention of serum-hepatitis infections. N Engl J Med (1971) 0.95
Expression and purification of native human granulocyte-macrophage colony-stimulating factor from an Escherichia coli secretion vector. DNA (1987) 0.91
Generation of anti-peptide monoclonal antibodies which recognize mature CSF-2 alpha (IL 3) protein. J Immunol (1985) 0.89
Primary structure of rabbit alpha-lactalbumin. Biochemistry (1979) 0.88
C-terminal sequence of the F'c fragment of human gamma G globulin. Nature (1968) 0.88
Stabilization of red blood cells by the plasticizer, diethylhexylphthalate. Vox Sang (1985) 0.87
Femoral osteotomy in Perthes' disease. Results at maturity. J Bone Joint Surg Br (1990) 0.85
Does anterior cruciate ligament reconstruction restore normal knee kinematics?: A prospective MRI analysis over two years. J Bone Joint Surg Br (2006) 0.84
Development of hemagglutination assays I. Attachment of anti-HBs antibody to stabilized erythrocytes. Vox Sang (1977) 0.83
Development of hemagglutination assays II. Enhancement in the sensitivity of an RPHA test for HBsAg. Vox Sang (1977) 0.83
Purification of low molecular weight factor VIII by affinity chromatography using factor VIII - sepharose. Thromb Res (1979) 0.81
Human rhinovirus 3C protease: cloning and expression of an active form in Escherichia coli. Biochemistry (1988) 0.81
Use of hydrophilicity plotting procedures to identify protein antigenic segments and other interaction sites. Methods Enzymol (1989) 0.80
Relationship between naturally occurring human antibodies to casein and autologous antiidiotypic antibodies: implications for the network theory. J Clin Immunol (1991) 0.78
The molecular forms of interleukin-1. Immunol Res (1986) 0.78
Protein antigen conformation: folding patterns and predictive algorithms; selection of antigenic and immunogenic peptides. Ann Sclavo Collana Monogr (1984) 0.78
Engineering proteins to enable their isolation in a biologically active form. Bioprocess Technol (1991) 0.76
Preparation of antihemophilic factor and fibronectin from human plasma cryoprecipitate. Transfusion (1984) 0.75
Interleukin-1 research. Science (1996) 0.75
Immunochemical studies on alpha-lactalbumin. Mol Immunol (1982) 0.75
Mapping the detailed specificity of a calcium-dependent monoclonal antibody through the use of soluble positional scanning combinatorial libraries: identification of potent calcium-independent antigens. Mol Divers (1995) 0.75
In vitro evaluation of the Medtronic cardioplegia safety system. J Extra Corpor Technol (2000) 0.75
Biochemistry of whole blood in poly(ethylene-co-ethylacrylate) experimental blood containers. Vox Sang (1985) 0.75
A data acquisition and processing system for the ultraviolet optical ultracentrifuge. Comput Biol Med (1974) 0.75
Identification of aqueous phase amino acid phenylthiohydantoins on polyamide sheets. Anal Biochem (1976) 0.75
Separation of two hepatitis B human antibody fractions by cold-ethanol precipitation. Vox Sang (1976) 0.75
Lymphokines: from conjecture to the clinic. Semin Oncol (1986) 0.75