Published in J Invest Dermatol on July 01, 1983
The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies. J Cell Biol (2001) 1.94
Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis. Nat Protoc (2010) 1.72
Production of human papillomavirus type 16 virions in a keratinocyte cell line. J Virol (1990) 1.66
Effect of growth environment on spatial expression of involucrin by human epidermal keratinocytes. Arch Dermatol Res (1987) 1.36
c-myc and c-fos expression in differentiating mouse primary keratinocytes. EMBO J (1986) 1.33
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Participation of adult mouse bone marrow cells in reconstitution of skin. Am J Pathol (2003) 1.05
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Organotypic collagen I assay: a malleable platform to assess cell behaviour in a 3-dimensional context. J Vis Exp (2011) 0.99
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Matriderm® 1 mm versus Integra® Single Layer 1.3 mm for one-step closure of full thickness skin defects: a comparative experimental study in rats. Pediatr Surg Int (2012) 0.93
Integrating macrophages into organotypic co-cultures: a 3D in vitro model to study tumor-associated macrophages. PLoS One (2012) 0.91
Restoration of growth potential in paraclones of human keratinocytes by a viral oncogene. Proc Natl Acad Sci U S A (1989) 0.90
Species-specific fibroblasts required for triggering invasiveness of partially transformed oral keratinocytes. Am J Pathol (2006) 0.88
Immortalized bovine pancreatic duct cells become tumorigenic after transfection with mutant k-ras. Virchows Arch (2001) 0.84
Development of tissue-engineered models of oral dysplasia and early invasive oral squamous cell carcinoma. Br J Cancer (2011) 0.82
"Trans-differentiation" from epidermal to mesenchymal/myogenic phenotype is associated with a drastic change in cell-cell and cell-matrix adhesion molecules. J Cell Biol (1993) 0.80
Human amniotic fluid derived cells can competently substitute dermal fibroblasts in a tissue-engineered dermo-epidermal skin analog. Pediatr Surg Int (2013) 0.80
A novel human leiomyoma tissue derived matrix for cell culture studies. BMC Cancer (2015) 0.79
The myofibroblast markers α-SM actin and β-actin are differentially expressed in 2 and 3-D culture models of fibrotic and normal skin. Cytotechnology (1998) 0.76
Vimentin expression in normal human keratinocytes grown in serum-free defined MCDB 153 medium. Arch Dermatol Res (1990) 0.75
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol (1988) 16.82
Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma. J Clin Oncol (2000) 9.70
Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA. Oncogene (1987) 4.02
Termination of stem cell maintenance in Arabidopsis floral meristems by interactions between WUSCHEL and AGAMOUS. Cell (2001) 3.17
p53 mutations in human immortalized epithelial cell lines. Carcinogenesis (1993) 2.82
Halting angiogenesis suppresses carcinoma cell invasion. Nat Med (1997) 2.61
Increased serum concentration of angiogenic factors in malignant melanoma patients correlates with tumor progression and survival. J Clin Oncol (2001) 2.58
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization. Nat Med (1998) 2.54
c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin. Cell (2000) 2.35
Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes. Proc Natl Acad Sci U S A (1996) 2.05
"False-positive" anti-neutrophil cytoplasmic antibodies in HIV infection. Lancet (1990) 1.94
The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies. J Cell Biol (2001) 1.94
Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer. Cell Death Differ (2006) 1.83
Tumorigenic conversion of immortal human keratinocytes through stromal cell activation. Proc Natl Acad Sci U S A (1998) 1.82
Simultaneous expression of two different types of intermediate sized filaments in mouse keratinocytes proliferating in vitro. Differentiation (1979) 1.68
Mutual induction of growth factor gene expression by epidermal-dermal cell interaction. J Cell Biol (1993) 1.60
c-Ha-ras oncogene expression in immortalized human keratinocytes (HaCaT) alters growth potential in vivo but lacks correlation with malignancy. Cancer Res (1990) 1.59
Increased soluble CD95 (sFas/CD95) serum level correlates with poor prognosis in melanoma patients. Clin Cancer Res (2001) 1.53
Keratinocyte growth regulation in fibroblast cocultures via a double paracrine mechanism. J Cell Sci (1999) 1.52
Epidermal organization and differentiation of HaCaT keratinocytes in organotypic coculture with human dermal fibroblasts. J Invest Dermatol (1999) 1.51
Expression of collagenase-3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase. J Cell Sci (2000) 1.50
Extracellular tyrosinase mRNA within apoptotic bodies is protected from degradation in human serum. Clin Chem (2001) 1.50
Phenotypic and genotypic characteristics of a cell line from a squamous cell carcinoma of human skin. J Natl Cancer Inst (1982) 1.49
Reformation of organized epidermal structure by transplantation of suspensions and cultures of epidermal and dermal cells. Cell Tissue Res (1982) 1.45
Keratinocyte growth regulation in defined organotypic cultures through IL-1-induced keratinocyte growth factor expression in resting fibroblasts. J Invest Dermatol (2000) 1.43
Preservation of morphological, functional, and karyotypic traits during long-term culture and in vivo passage of two human skin squamous cell carcinomas. Cancer Res (1983) 1.42
Multiple stages and genetic alterations in immortalization, malignant transformation, and tumor progression of human skin keratinocytes. Mol Carcinog (1998) 1.42
Environmental modulation of the expression of differentiation and malignancy in six human squamous cell carcinoma cell lines. Cancer Res (1985) 1.40
Epithelial-mesenchymal interactions control basement membrane production and differentiation in cultured and transplanted mouse keratinocytes. Cell Tissue Res (1986) 1.39
Mouse epidermal cell cultures. II. Isolation, characterization and cultivation of epidermal cells from perinatal mouse skin. Exp Cell Res (1975) 1.39
Differentiation specific functions in cultured and transplanted mouse keratinocytes: environmental influences on ultrastructure and keratin expression. Differentiation (1984) 1.39
Effect of growth environment on spatial expression of involucrin by human epidermal keratinocytes. Arch Dermatol Res (1987) 1.36
Dynamics of basement membrane formation by keratinocyte-fibroblast interactions in organotypic skin culture. Exp Cell Res (1998) 1.33
Sustained nontumorigenic phenotype correlates with a largely stable chromosome content during long-term culture of the human keratinocyte line HaCaT. Genes Chromosomes Cancer (1997) 1.32
Organotypic keratinocyte cocultures in defined medium with regular epidermal morphogenesis and differentiation. J Invest Dermatol (1999) 1.32
Allele-specific methylation of the human c-Ha-ras-1 gene. Cell (1987) 1.31
Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones. Differentiation (1989) 1.30
Reduced serum 25-hydroxyvitamin D levels in stage IV melanoma patients. Anticancer Res (2009) 1.29
Detection of a human melanoma-associated antigen, p97, in histological sections of primary human melanomas. Int J Cancer (1982) 1.29
Proteolytic modification of acidic and basic keratins during terminal differentiation of mouse and human epidermis. Eur J Biochem (1984) 1.28
A prospective randomized multicentre phase III trial of fotemustine plus whole brain irradiation versus fotemustine alone in cerebral metastases of malignant melanoma. Melanoma Res (2003) 1.24
Detection of circulating melanoma cells by specific amplification of tyrosinase complementary DNA is not a reliable tumor marker in melanoma patients: a clinical two-center study. J Clin Oncol (1997) 1.20
Epidermal differentiation and basement membrane formation by HaCaT cells in surface transplants. Eur J Cell Biol (1998) 1.20
Organotypic cocultures with genetically modified mouse fibroblasts as a tool to dissect molecular mechanisms regulating keratinocyte growth and differentiation. J Invest Dermatol (2001) 1.19
Phenotypic and cytogenetic characteristics of different stages during spontaneous transformation of mouse keratinocytes in vitro. Carcinog Compr Surv (1985) 1.17
Autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor in human gliomas with tumor progression. Am J Pathol (1999) 1.16
Differential modulation of epidermal keratinization in immortalized (HaCaT) and tumorigenic human skin keratinocytes (HaCaT-ras) by retinoic acid and extracellular Ca2+. Differentiation (1993) 1.14
Present concepts and future outlook: function of peroxisome proliferator-activated receptors (PPARs) for pathogenesis, progression, and therapy of cancer. J Cell Physiol (2007) 1.14
Environmental induction of differentiation-specific keratins in malignant mouse keratinocyte lines. Eur J Cell Biol (1986) 1.14
Keratins of the human hair follicle: "hyperproliferative" keratins consistently expressed in outer root sheath cells in vivo and in vitro. Differentiation (1987) 1.12
Formation of epidermis after reimplantation of pure primary epidermal cell cultures from perinatal mouse skin. J Natl Cancer Inst (1974) 1.11
Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization. Proc Natl Acad Sci U S A (1999) 1.11
Expression and functional significance of vascular endothelial growth factor receptors in human tumor cells. Lab Invest (1999) 1.11
Transcription of the human loricrin gene in vitro is induced by calcium and cell density and suppressed by retinoic acid. J Invest Dermatol (1991) 1.09
Novel p63 target genes involved in paracrine signaling and keratinocyte differentiation. Cell Death Dis (2010) 1.08
Spontaneous in vitro malignant transformation in a xeroderma pigmentosum fibroblast line. Int J Cancer (1983) 1.08
A novel polymorphism in the 5' promoter region of the human interleukin-4 receptor alpha-chain gene is associated with decreased soluble interleukin-4 receptor protein levels. Immunogenetics (2001) 1.07
Soluble human leukocyte antigen--G serum level is elevated in melanoma patients and is further increased by interferon-alpha immunotherapy. Cancer (2001) 1.06
Genetic characterization of a human skin carcinoma progression model: from primary tumor to metastasis. J Invest Dermatol (2000) 1.06
Normal keratinocytes suppress early stages of neoplastic progression in stratified epithelium. Cancer Res (1998) 1.06
Isolation and characterization of the cyanogen bromide peptides from the alpha2 chain of calf skin collagen. FEBS Lett (1970) 1.05
A promoter polymorphism in the CD14 gene is associated with elevated levels of soluble CD14 but not with IgE or atopic diseases. Allergy (2004) 1.04
Dacarbazine and interferon alpha with or without interleukin 2 in metastatic melanoma: a randomized phase III multicentre trial of the Dermatologic Cooperative Oncology Group (DeCOG). Br J Cancer (2001) 1.02
[The "Stade éphélide" of precancerous melanosis. A comparative clinical, histopathological, and electron microscopical study]. Arch Dermatol Forsch (1970) 1.01
Suppression in vivo of human papillomavirus type 18 E6-E7 gene expression in nontumorigenic HeLa X fibroblast hybrid cells. J Virol (1990) 1.01
Telomerase is not an epidermal stem cell marker and is downregulated by calcium. J Invest Dermatol (1998) 1.00
Histomorphological and biochemical differentiation capacity in organotypic co-cultures of primary gingival cells. J Periodontal Res (1997) 1.00
Clusterin and DNA repair: a new function in cancer for a key player in apoptosis and cell cycle control. J Mol Histol (2006) 1.00
Sperm morphology assessment using strict criteria and male fertility under in-vivo conditions of conception. Hum Reprod (1996) 0.99