Published in Annu Rev Neurosci on January 01, 1983
Genetic triple dissociation reveals multiple roles for dopamine in reinforcement learning. Proc Natl Acad Sci U S A (2007) 3.33
Opponency revisited: competition and cooperation between dopamine and serotonin. Neuropsychopharmacology (2010) 2.34
From reinforcement learning models to psychiatric and neurological disorders. Nat Neurosci (2011) 2.20
Retinal dopamine and form-deprivation myopia. Proc Natl Acad Sci U S A (1989) 1.75
Phenotypical characterization of the rat striatal neurons expressing the D1 dopamine receptor gene. Proc Natl Acad Sci U S A (1991) 1.41
Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes. Proc Natl Acad Sci U S A (1991) 1.39
Understanding decision-making deficits in neurological conditions: insights from models of natural action selection. Philos Trans R Soc Lond B Biol Sci (2007) 1.35
Expression of striatal D1 dopamine receptors coupled to inositol phosphate production and Ca2+ mobilization in Xenopus oocytes. Proc Natl Acad Sci U S A (1990) 1.27
Dopaminergic modulation of endocannabinoid-mediated plasticity at GABAergic synapses in the prefrontal cortex. J Neurosci (2010) 1.24
Dopamine receptor gene expression by enkephalin neurons in rat forebrain. Proc Natl Acad Sci U S A (1990) 1.20
Psychotomimetic opiate receptors labeled and visualized with (+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)piperidine. Proc Natl Acad Sci U S A (1984) 1.17
Single K+ channels activated by D2 dopamine receptors in acutely dissociated neurons from rat corpus striatum. Proc Natl Acad Sci U S A (1988) 1.06
D1-type dopamine receptors inhibit growth cone motility in cultured retina neurons: evidence that neurotransmitters act as morphogenic growth regulators in the developing central nervous system. Proc Natl Acad Sci U S A (1988) 0.99
Direct visualization and cellular localization of D1 and D2 dopamine receptors in rat forebrain by use of fluorescent ligands. Proc Natl Acad Sci U S A (1989) 0.88
Signaling from the cytoplasm to the nucleus in striatal medium-sized spiny neurons. Front Neuroanat (2011) 0.88
A review of the discovery, pharmacological characterization, and behavioral effects of the dopamine D2-like receptor antagonist eticlopride. CNS Neurosci Ther (2008) 0.87
D1-type dopamine receptors inhibit growth cone motility in cultured retina neurons: evidence that neurotransmitters act as morphogenic growth regulators in the developing central nervous system. Proc Natl Acad Sci U S A (1988) 0.85
Striatal D1- and D2-type dopamine receptors are linked to motor response inhibition in human subjects. J Neurosci (2015) 0.84
Effects of prenatal exposure to methylmercury on dopamine-mediated locomotor activity and dopamine D2 receptor binding. Naunyn Schmiedebergs Arch Pharmacol (2003) 0.81
Identification of a D1 dopamine receptor, not linked to adenylate cyclase, on lactotroph cells. Br J Pharmacol (1991) 0.81
D1 and D2 receptor-mediated dopaminergic modulation of visual responses in cat dorsal lateral geniculate nucleus. J Physiol (2002) 0.79
Dopamine receptor turnover rates in rat striatum are age-dependent. Proc Natl Acad Sci U S A (1984) 0.79
Selective D-1 dopamine receptor agonist effects in hyperkinetic extrapyramidal disorders. J Neurol Neurosurg Psychiatry (1989) 0.77
Dopamine modulates the functional organization of the orbitofrontal cortex. J Neurosci (2017) 0.75
Pharmacological modulation of lateral habenular dopamine D2 receptors alters the anxiogenic response to cocaine in a runway model of drug self-administration. Behav Brain Res (2016) 0.75
D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons. Science (1990) 8.07
Complex transcriptional units: diversity in gene expression by alternative RNA processing. Annu Rev Biochem (1986) 4.73
Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science (1976) 4.07
Regulation of transmembrane signaling by receptor phosphorylation. Cell (1987) 3.74
Molecular mechanisms of receptor desensitization using the beta-adrenergic receptor-coupled adenylate cyclase system as a model. Nature (1985) 3.74
Characterization of alpha 1-adrenergic receptor subtypes in rat brain: a reevaluation of [3H]WB4104 and [3H]prazosin binding. Mol Pharmacol (1986) 2.84
Splice commitment dictates neuron-specific alternative RNA processing in calcitonin/CGRP gene expression. Cell (1987) 2.58
The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther (1994) 2.27
Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation. Nature (1987) 2.16
Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes. Mol Pharmacol (1976) 2.09
Molecular cloning and expression of a D1 dopamine receptor linked to adenylyl cyclase activation. Proc Natl Acad Sci U S A (1990) 1.87
Multiple D2 dopamine receptors produced by alternative RNA splicing. Nature (1990) 1.84
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. J Biol Chem (1993) 1.84
Restricted eating with weight loss selectively decreases extracellular dopamine in the nucleus accumbens and alters dopamine response to amphetamine, morphine, and food intake. J Neurosci (1995) 1.77
A candidate mouse model for Prader-Willi syndrome which shows an absence of Snrpn expression. Nat Genet (1992) 1.76
Stereospecificity of interaction of neuroleptic drugs with neurotransmitters and correlation with clinical potency. Nature (1976) 1.71
Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes. Neuropsychopharmacology (1999) 1.60
Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin gene-related peptide. Science (1985) 1.60
Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease. J Neurosci (1998) 1.59
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Mol Pharmacol (1993) 1.59
The pharmacological and anatomical substrates of the amphetamine response in the rat. Brain Res (1975) 1.55
Cloning and expression of an A1 adenosine receptor from rat brain. Mol Pharmacol (1991) 1.51
Receptor binding and pharmacological activity of opiates in the guinea-pig intestine. J Pharmacol Exp Ther (1975) 1.50
A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice. Proc Natl Acad Sci U S A (1996) 1.48
Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution. Proc Natl Acad Sci U S A (1986) 1.46
Maternal imprinting of human SNRPN, a gene deleted in Prader-Willi syndrome. Nat Genet (1994) 1.45
Opiate receptor binding affected differentially by opiates and opioid peptides. Eur J Pharmacol (1979) 1.45
Homologous desensitization of adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor. J Biol Chem (1985) 1.41
Molecular cloning of a novel G protein-coupled receptor related to the opiate receptor family. J Neurochem (1995) 1.40
The D1 dopamine receptor antagonist SCH 23390 increases cocaine self-administration in the rat. Neurosci Lett (1987) 1.39
Desensitization of turkey erythrocyte adenylate cyclase. Beta-adrenergic receptor phosphorylation is correlated with attenuation of adenylate cyclase activity. J Biol Chem (1984) 1.38
Phorbol diesters promote beta-adrenergic receptor phosphorylation and adenylate cyclase desensitization in duck erythrocytes. Biochem Biophys Res Commun (1984) 1.37
Role of the D1A dopamine receptor in the pathogenesis of genetic hypertension. J Clin Invest (1996) 1.34
Dopamine receptor binding in the corpus striatum of mammalian brain. Proc Natl Acad Sci U S A (1975) 1.29
The dopamine receptor: differential binding of d-LSD and related agents to agonist and antagonist states. Life Sci (1975) 1.29
Spatial learning deficit in dopamine D(1) receptor knockout mice. Eur J Pharmacol (1999) 1.27
Expression of striatal D1 dopamine receptors coupled to inositol phosphate production and Ca2+ mobilization in Xenopus oocytes. Proc Natl Acad Sci U S A (1990) 1.27
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. J Neurochem (1996) 1.26
Blockage of amphetamine induced motor stimulation and stereotypy in the adult rat following neonatal treatment with 6-hydroxydopamine. Brain Res (1973) 1.26
Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats. Proc Natl Acad Sci U S A (1997) 1.26
The role of forebrain dopamine systems in amphetamine induced stereotyped behavior in the rat. Psychopharmacologia (1974) 1.25
Antischizophrenic drugs: chronic treatment elevates dopamine receptor binding in brain. Science (1977) 1.24
Anterior pituitary dopamine receptors. Demonstration of interconvertible high and low affinity states of the D-2 dopamine receptor. J Biol Chem (1982) 1.23
Behavioral characterization of dopamine D5 receptor null mutant mice. Behav Neurosci (2001) 1.22
A simple and sensitive radioreceptor assay for antischizophrenic drugs in blood. Nature (1977) 1.22
Receptor adaptations to centrally acting drugs. Annu Rev Pharmacol Toxicol (1981) 1.22
Four 5-hydroxytryptamine7 (5-HT7) receptor isoforms in human and rat produced by alternative splicing: species differences due to altered intron-exon organization. J Neurochem (1997) 1.20
Viral gene delivery selectively restores feeding and prevents lethality of dopamine-deficient mice. Neuron (1999) 1.19
Modulatory actions of dopamine on NMDA receptor-mediated responses are reduced in D1A-deficient mutant mice. J Neurosci (1996) 1.17
The role of phosphorylation/dephosphorylation in agonist-induced desensitization of D1 dopamine receptor function: evidence for a novel pathway for receptor dephosphorylation. Mol Pharmacol (2001) 1.17
Dopamine receptor binding enhancement accompanies lesion-induced behavioral supersensitivity. Science (1977) 1.16
Disruption of dopamine D1 receptor gene expression attenuates alcohol-seeking behavior. Eur J Pharmacol (1998) 1.14
Guanine nucleotides distinguish between two dopamine receptors. Nature (1979) 1.10
Regulation of gene expression in vivo following transduction by two separate rAAV vectors. Nat Biotechnol (1998) 1.09
Identification of subtypes of [3H]prazosin-labelled alpha 1 receptor binding sites in rat brain. Eur J Pharmacol (1985) 1.06
The opiate receptor: a model explaining structure-activity relationships of opiate agonists and antagonists. Proc Natl Acad Sci U S A (1976) 1.05
Localization of serotonin subtype 6 receptor messenger RNA in the rat brain by in situ hybridization histochemistry. Neuroscience (1995) 1.04
Dopamine receptors localised on cerebral cortical afferents to rat corpus striatum. Nature (1978) 1.03
Desensitization of the turkey erythrocyte beta-adrenergic receptor in a cell-free system. Evidence that multiple protein kinases can phosphorylate and desensitize the receptor. J Biol Chem (1985) 1.03
Regulation of tissue-specific splicing of the calcitonin/calcitonin gene-related peptide gene by RNA-binding proteins. J Biol Chem (1993) 1.03
Molecular characteristics of mammalian dopamine receptors. Pharmacol Toxicol (1997) 1.02
D1-like dopaminergic activation of phosphoinositide hydrolysis is independent of D1A dopamine receptors: evidence from D1A knockout mice. Mol Pharmacol (1997) 1.02
Developmental regulation of 5-HT2 and 5-HT1c mRNA and receptor levels. Brain Res Dev Brain Res (1991) 0.99
The binding-site crevice of the D4 dopamine receptor is coupled to three distinct sites of allosteric modulation. J Pharmacol Exp Ther (2001) 0.99
Function and distribution of three rat 5-hydroxytryptamine7 (5-HT7) receptor isoforms produced by alternative splicing. Neuropharmacology (1998) 0.97
Functional roles of dopamine D2 and D3 autoreceptors on nigrostriatal neurons analyzed by antisense knockdown in vivo. J Neurosci (1997) 0.96
Characterization of anti-peptide antibodies for the localization of D2 dopamine receptors in rat striatum. Proc Natl Acad Sci U S A (1991) 0.96
Serum levels of neuroleptics measured by dopamine radioreceptor assay and some clinical observations. Psychiatry Res (1979) 0.96
Increased brain dopamine and dopamine receptors in schizophrenia. Arch Gen Psychiatry (1982) 0.96
Transfected D2 dopamine receptors mediate the potentiation of arachidonic acid release in Chinese hamster ovary cells. Mol Pharmacol (1991) 0.96
3H-Spiroperidol labels serotonin receptors in rat cerebral cortex and hippocampus. Eur J Pharmacol (1978) 0.95
Agonist-induced morphologic decrease in cellular D1A dopamine receptor staining. Synapse (1997) 0.95
Amphetamine response in rat after dopamine neurone destruction. Nat New Biol (1972) 0.94
Dopamine receptor binding: differentiation of agonist and antagonist states with 3H-dopamine and 3H-haloperidol. Life Sci (1975) 0.94
Regulation of D(1) dopamine receptors with mutations of protein kinase phosphorylation sites: attenuation of the rate of agonist-induced desensitization. Mol Pharmacol (1999) 0.94
Forskolin potentiates the stimulation of rat striatal adenylate cyclase mediated by D-1 dopamine receptors, guanine nucleotides, and sodium fluoride. J Neurochem (1986) 0.93
Dopamine receptor distribution in the rat CNS: elucidation using anti-peptide antisera directed against D1A and D3 subtypes. Brain Res (1994) 0.93
Conservation of behavioural topography to dopamine D1-like receptor agonists in mutant mice lacking the D1A receptor implicates a D1-like receptor not coupled to adenylyl cyclase. Neuroscience (1999) 0.92
Dopamine receptor binding regulated by guanine nucleotides. Mol Pharmacol (1979) 0.92
Reconstitution of a hormone-sensitive adenylate cyclase system. The pure beta-adrenergic receptor and guanine nucleotide regulatory protein confer hormone responsiveness on the resolved catalytic unit. J Biol Chem (1984) 0.92
Cellular distribution of the rat D4 dopamine receptor protein in the CNS using anti-receptor antisera. Brain Res (1997) 0.92
Stimulation of type 1 and type 8 Ca2+/calmodulin-sensitive adenylyl cyclases by the Gs-coupled 5-hydroxytryptamine subtype 5-HT7A receptor. J Biol Chem (1998) 0.92
Cell-free desensitization of catecholamine-sensitive adenylate cyclase. Agonist- and cAMP-promoted alterations in turkey erythrocyte beta-adrenergic receptors. J Biol Chem (1984) 0.92
Chronic fluoxetine reduces serotonin transporter mRNA and 5-HT1B mRNA in a sequential manner in the rat dorsal raphe nucleus. Neuropsychopharmacology (1996) 0.92
Characterization of novel fluorescent ligands with high affinity for D1 and D2 dopaminergic receptors. J Neurochem (1989) 0.91
Cloning of the mouse 5-HT6 serotonin receptor and mutagenesis studies of the third cytoplasmic loop. Brain Res Mol Brain Res (2001) 0.91
Progress in direct striatal delivery of L-dopa via gene therapy for treatment of Parkinson's disease using recombinant adeno-associated viral vectors. Exp Neurol (1999) 0.91
Synthesis and processing of D2 dopamine receptors. Biochemistry (1993) 0.91
3H-Spiroperidol labels dopamine receptors in pituitary and brain. Eur J Pharmacol (1977) 0.91
Expression of dopamine D1A receptor gene in proximal tubule of rat kidneys. Am J Physiol (1993) 0.91
Organ specificity of the dopamine1 receptor/adenylyl cyclase coupling defect in spontaneously hypertensive rats. Am J Physiol (1993) 0.91