PubRank

M D Faiman

Author PubWeight™ 30.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Elimination kinetics of disulfiram in alcoholics after single and repeated doses. Clin Pharmacol Ther 1984 1.11
2 Identification of the human and rat P450 enzymes responsible for the sulfoxidation of S-methyl N,N-diethylthiolcarbamate (DETC-ME). The terminal step in the bioactivation of disulfiram. Drug Metab Dispos 1995 1.03
3 Carbamoylation of brain glutamate receptors by a disulfiram metabolite. J Biol Chem 1997 0.99
4 In vitro and in vivo inhibition of rat liver aldehyde dehydrogenase by S-methyl N,N-diethylthiolcarbamate sulfoxide, a new metabolite of disulfiram. Biochem Pharmacol 1992 0.98
5 Role of taurine in regulation of intracellular calcium level and neuroprotective function in cultured neurons. J Neurosci Res 2001 0.97
6 Comparative aspects of disulfiram and its metabolites in the disulfiram-ethanol reaction in the rat. Biochem Pharmacol 1989 0.90
7 Distribution of S35 disulfiram and metabolites in mice, and metabolism of S35 disulfiram in the dog. Res Commun Chem Pathol Pharmacol 1978 0.89
8 Disulfiram metabolism as a requirement for the inhibition of rat liver mitochondrial low Km aldehyde dehydrogenase. Biochem Pharmacol 1991 0.87
9 Role of flavin-dependent monooxygenases and cytochrome P450 enzymes in the sulfoxidation of S-methyl N,N-diethylthiolcarbamate. Biochem Pharmacol 1993 0.87
10 In vivo pharmacodynamic studies of the disulfiram metabolite S-methyl N,N-diethylthiolcarbamate sulfoxide: inhibition of liver aldehyde dehydrogenase. Alcohol Clin Exp Res 1994 0.85
11 Disulfiram distribution and elimination in the rat after oral and intraperitoneal administration. Alcohol Clin Exp Res 1980 0.84
12 S-methyl-N,N-diethylthiolcarbamate: a disulfiram metabolite and potent rat liver mitochondrial low Km aldehyde dehydrogenase inhibitor. Alcohol 1990 0.83
13 Bioactivation of S-methyl N,N-diethylthiolcarbamate to S-methyl N,N-diethylthiolcarbamate sulfoxide. Implications for the role of cytochrome P450. Biochem Pharmacol 1993 0.83
14 A rapid and simple radioactive method for the determination of disulfiram and its metabolites from a single sample of biological fluid or tissue. Res Commun Chem Pathol Pharmacol 1977 0.82
15 Characterization of diethyldithiocarbamate methyl ester sulfine as an intermediate in the bioactivation of disulfiram. J Pharmacol Exp Ther 1995 0.81
16 Protein phosphorylation and taurine biosynthesis in vivo and in vitro. J Neurosci 1997 0.81
17 S-methyl N,N-diethylthiolcarbamate sulfone, an in vitro and in vivo inhibitor of rat liver mitochondrial low Km aldehyde dehydrogenase. Biochem Pharmacol 1994 0.81
18 Diethyldithiocarbamic acid-methyl ester: a metabolite of disulfiram and its alcohol sensitizing properties in the disulfiram-ethanol reaction. Alcohol 1988 0.81
19 Radioactive and nonradioactive methods for the in vivo determination of disulfiram, diethyldithiocarbamate, and diethyldithiocarbamate-methyl ester. Alcohol Clin Exp Res 1978 0.81
20 Identification of the human P-450 enzymes responsible for the sulfoxidation and thiono-oxidation of diethyldithiocarbamate methyl ester: role of P-450 enzymes in disulfiram bioactivation. Alcohol Clin Exp Res 1998 0.80
21 S-methyl-N,N-diethylthiocarbamate sulfoxide elicits neuroprotective effect against N-methyl-D-aspartate receptor-mediated neurotoxicity. J Biomed Sci 2001 0.80
22 Inhibition of rat liver low Km aldehyde dehydrogenase by thiocarbamate herbicides. Occupational implications. Biochem Pharmacol 1995 0.80
23 Protection with disulfiram from central and pulmonary oxygen toxicity. Biochem Pharmacol 1971 0.80
24 Determination of disulfiram and metabolites from biological fluids by high-performance liquid chromatography. J Chromatogr 1980 0.79
25 Isolated perfused lung histamine release, lipid peroxidation, and tissue superoxide dismutase from rats exposed to normobaric hyperoxia. Toxicology 1986 0.79
26 Regulation of taurine biosynthesis and its physiological significance in the brain. Adv Exp Med Biol 1998 0.79
27 Effect of disulfiram on oxygen toxicity in beagle dogs. Aerosp Med 1974 0.79
28 Free radical formation and lipid peroxidation in rat and mouse cerebral cortex slices exposed to high oxygen pressure. Brain Res 1982 0.79
29 Mode of action of taurine and regulation dynamics of its synthesis in the CNS. Adv Exp Med Biol 2000 0.78
30 Brain energetics in oxygen-induced convulsions. J Neurochem 1974 0.77
31 Diethyldithiocarbamate methyl ester sulfoxide, an inhibitor of rat liver mitochondrial low Km aldehyde dehydrogenase and putative metabolite of disulfiram. Alcohol Clin Exp Res 1994 0.77
32 Diethyldithiocarbamic acid-methyl ester distribution, elimination, and LD50 in the rat after intraperitoneal administration. Alcohol Clin Exp Res 1983 0.77
33 Glutathione- and glutathione-S-transferase-dependent oxidative desulfuration of the thione xenobiotic diethyldithiocarbamate methyl ester. Mol Pharmacol 1994 0.76
34 NADPH-dependent, regioselective S-oxidation of a thionosulfur- and thioether-containing xenobiotic, diethyldithiocarbamate methyl ester by rat liver microsomes. Drug Metab Dispos 1994 0.76
35 Brain gamma-aminobutyric acid, glutamic acid decarboxylase, glutamate, and ammonia in mice during hyperbaric oxygenation. J Neurochem 1977 0.76
36 Cerebral oxidized and reduced nicotinamide-adenine dinucleotide phosphate and glucose 6-phosphate dehydrogenase in mice during exposure to high oxygen pressure. Biochem J 1978 0.76
37 Neurotoxic effect of acamprosate, n-acetyl-homotaurine, in cultured neurons. J Biomed Sci 2001 0.75
38 NAD+ and NADH in brain cortex from mice exposed to high oxygen pressure. Toxicology 1982 0.75
39 Case report of acute disulfiram overdose. Am J Psychiatry 1983 0.75
40 Disulfiram and CS2 toxicity. Am J Psychiatry 1978 0.75
41 Disulfiram-ethanol reaction in the rat. 1. Blood alcohol, acetaldehyde, and liver aldehyde dehydrogenase relationships. Alcohol Clin Exp Res 1986 0.75
42 Glutathione carbamoylation with S-methyl N,N-diethylthiolcarbamate sulfoxide and sulfone. Mitochondrial low Km aldehyde dehydrogenase inhibition and implications for its alcohol-deterrent action. Biochem Pharmacol 1998 0.75
43 Brain norepinephrine and serotonin in central oxygen toxicity. Life Sci I 1971 0.75
44 Hyperbaric oxygenation and brain norepinephrine and 5-hydroxytryptamine: oxygen-pressure interactions. Life Sci 1969 0.75
45 Post-mortem degradation kinetics of brain norepinephrine. Biochem Pharmacol 1973 0.75
46 Glutathione and non-protein sulfhydryl in cerebral cortex and lung in mice exposed to high oxygen pressure. Toxicology 1982 0.75
47 Segregation kinetics of particulate solids systems. IV. Effect of particle shape on energy requirements. J Pharm Sci 1967 0.75
48 Effect of high oxygen pressure on brain norepinephrine and serotonin turnover. Eur J Pharmacol 1973 0.75
49 Elimination characteristics of disulfiram over time in five alcoholic volunteers: a preliminary study. Am J Psychiatry 1982 0.75
50 Hypothermia as an index of the disulfiram-ethanol reaction in the rat. Alcohol 1985 0.75
51 The role of lipid, free radical initiator, and oxygen on the kinetics of lipid peroxidation. Toxicol Appl Pharmacol 1982 0.75
52 Segregation kinetics of particulate solids systems. 3. Dependence on agitation intensity. J Pharm Sci 1965 0.75
53 The effect of in vivo hyperoxic exposure on the release of endogenous histamine from the rat isolated perfused lung. Toxicol Appl Pharmacol 1984 0.75
54 Cerebral and blood glucose in central oxygen poisoning. Undersea Biomed Res 1978 0.75
55 Plasma measurements of disulfiram and its metabolites in a case of severe disulfiram-ethanol reaction. Psychiatr J Univ Ott 1986 0.75
56 Pulmonary oxygen toxicity in the rat and the role of histamine. Biochem Pharmacol 1986 0.75