Published in Proc Natl Acad Sci U S A on October 01, 1980
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
Transcription of adenovirus type 2 genes in a cell-free system: apparent heterogeneity of initiation at some promoters. Mol Cell Biol (1981) 7.12
In vitro transcription of adenovirus. J Virol (1981) 7.06
Construction and analysis of simian virus 40 origins defective in tumor antigen binding and DNA replication. Proc Natl Acad Sci U S A (1980) 7.04
Transcription of the beta-like globin genes and pseudogenes of the goat in a cell-free system. Nucleic Acids Res (1981) 6.63
Human polyomavirus JC virus genome. J Virol (1984) 5.87
Topography of simian virus 40 A protein-DNA complexes: arrangement of pentanucleotide interaction sites at the origin of replication. J Virol (1983) 5.00
E1A control of gene expression is mediated by sequences 5' to the transcriptional starts of the early viral genes. Mol Cell Biol (1983) 4.84
Double-stranded RNA activates binding of NF-kappa B to an inducible element in the human beta-interferon promoter. EMBO J (1989) 4.10
Stimulation of simian virus 40 late gene expression by simian virus 40 tumor antigen. Proc Natl Acad Sci U S A (1984) 3.80
Mutational analysis of simian virus 40 T antigen: isolation and characterization of mutants with deletions in the T-antigen gene. Mol Cell Biol (1983) 3.67
Functional organization of the simian virus 40 origin of DNA replication. Mol Cell Biol (1986) 3.40
T-antigen-DNA polymerase alpha complex implicated in simian virus 40 DNA replication. Mol Cell Biol (1986) 3.22
Simian virus 40 large T antigen is phosphorylated at multiple sites clustered in two separate regions. J Virol (1982) 3.18
Biochemical activities of T-antigen proteins encoded by simian virus 40 A gene deletion mutants. Mol Cell Biol (1983) 3.06
Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeat. J Virol (1992) 2.93
The high affinity binding site on polyoma virus DNA for the viral large-T protein. Nucleic Acids Res (1981) 2.67
Sequences controlling in vitro transcription of SV40 promoters. EMBO J (1983) 2.65
Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo. Proc Natl Acad Sci U S A (1981) 2.63
Analysis of an activatable promoter: sequences in the simian virus 40 late promoter required for T-antigen-mediated trans activation. Mol Cell Biol (1985) 2.55
Cyclic AMP and phorbol ester-stimulated transcription mediated by similar DNA elements that bind distinct proteins. Proc Natl Acad Sci U S A (1988) 2.40
DNA binding properties of simian virus 40 temperature-sensitive A proteins. J Virol (1982) 2.31
A T to A base substitution and small deletions in the conalbumin TATA box drastically decrease specific in vitro transcription. Nucleic Acids Res (1981) 2.31
Regulation of human ribosomal RNA transcription. Proc Natl Acad Sci U S A (1983) 2.25
Regulation of SV40 DNA replication by phosphorylation of T antigen. EMBO J (1987) 2.17
An in vitro system for human cytomegalovirus immediate early 2 protein (IE2)-mediated site-dependent repression of transcription and direct binding of IE2 to the major immediate early promoter. Proc Natl Acad Sci U S A (1993) 2.13
In vitro activation of the HIV-1 enhancer in extracts from cells treated with a phorbol ester tumor promoter. EMBO J (1987) 2.09
Simian virus 40 major late promoter: a novel tripartite structure that includes intragenic sequences. Mol Cell Biol (1988) 2.09
Homologous upstream sequences near Epstein-Barr virus promoters. Proc Natl Acad Sci U S A (1983) 1.98
An enhancer sequence from bovine papilloma virus DNA consists of two essential regions. Nucleic Acids Res (1984) 1.98
Detailed characterization of an apparently unspliced beta herpes simplex virus type 1 gene mapping in the interior of another. J Virol (1982) 1.84
Cell-type-specific transcription of an immunoglobulin kappa light chain gene in vitro. Proc Natl Acad Sci U S A (1986) 1.82
Isolation and characterization of human DNA fragments with nucleotide sequence homologies with the simian virus 40 regulatory region. Mol Cell Biol (1982) 1.82
Simian virus 40 origin DNA-binding domain on large T antigen. J Virol (1986) 1.80
Expression of simian virus 40 T antigen in Escherichia coli: localization of T-antigen origin DNA-binding domain to within 129 amino acids. J Virol (1988) 1.77
Initiation and regulation of simian virus 40 early transcription in vitro. J Virol (1982) 1.77
Uninfected cell polymerase efficiently transcribes early but not late herpes simplex virus type 1 mRNA. Proc Natl Acad Sci U S A (1981) 1.76
DNA-binding region of the simian virus 40 tumor antigen. J Virol (1986) 1.62
Sequences in the polyomavirus DNA regulatory region involved in viral DNA replication and early gene expression. J Virol (1985) 1.60
Studies on the origin-specific DNA-binding domain of simian virus 40 large T antigen. J Virol (1987) 1.56
Transcription factor Sp1 recognizes promoter sequences from the monkey genome that are simian virus 40 promoter. Proc Natl Acad Sci U S A (1985) 1.54
The minimum replication origin of merkel cell polyomavirus has a unique large T-antigen loading architecture and requires small T-antigen expression for optimal replication. J Virol (2009) 1.52
Transcription of adenovirus 2 major late and peptide IX genes under conditions of in vitro nucleosome assembly. Mol Cell Biol (1987) 1.52
Simian virus 40 large T-antigen point mutants that are defective in viral DNA replication but competent in oncogenic transformation. Mol Cell Biol (1984) 1.51
Phosphorylation downregulates the DNA-binding activity of simian virus 40 T antigen. J Virol (1986) 1.50
Effect of mutations and deletions in a bicistronic mRNA on the synthesis of influenza B virus NB and NA glycoproteins. J Virol (1989) 1.50
Location of sequences in polyomavirus DNA that are required for early gene expression in vivo and in vitro. Mol Cell Biol (1984) 1.49
Repression of human immunodeficiency virus type 1 through the novel cooperation of human factors YY1 and LSF. J Virol (1997) 1.48
Mapping the transcriptional transactivation function of simian virus 40 large T antigen. J Virol (1991) 1.47
Regulation of polyomavirus transcription by large tumor antigen. Proc Natl Acad Sci U S A (1984) 1.38
Essential nucleotides in the polyomavirus origin region. J Virol (1984) 1.36
Rapid induction of hemopoietic neoplasms in newborn mice by a raf(mil)/myc recombinant murine retrovirus. J Virol (1985) 1.35
Mutational analysis of simian virus 40 large T antigen DNA binding sites. EMBO J (1984) 1.31
Effects of in vitro dephosphorylation on DNA-binding and DNA helicase activities of simian virus 40 large tumor antigen. J Virol (1988) 1.31
Selective repression of transcriptional activators at a distance by the Drosophila Krüppel protein. Proc Natl Acad Sci U S A (1993) 1.30
Unrearranged immunoglobulin variable region genes have a functional promoter. Nucleic Acids Res (1982) 1.23
Ability of nonpermissive mouse cells to express a simian virus 40 late function(s). J Virol (1981) 1.21
A downstream-element-binding factor facilitates assembly of a functional preinitiation complex at the simian virus 40 major late promoter. Mol Cell Biol (1990) 1.21
Production of simian virus 40 large tumor antigen in bacteria: altered DNA-binding specificity and dna-replication activity of underphosphorylated large tumor antigen. Proc Natl Acad Sci U S A (1989) 1.20
Allosteric control of simian virus 40 T-antigen binding to viral origin DNA. J Virol (1986) 1.15
Both trans-acting factors and chromatin structure are involved in the regulation of transcription from the early and late promoters in simian virus 40 chromosomes. J Virol (1985) 1.15
Requirement for distal upstream sequences for maximal transcription in vitro of early region IV of adenovirus. Mol Cell Biol (1984) 1.12
Efficient transcriptional activation of many simple modular promoters by simian virus 40 large T antigen. J Virol (1993) 1.12
Nuclear subcompartmentalization of simian virus 40 large T antigen: evidence for in vivo regulation of biochemical activities. J Virol (1989) 1.12
Negative regulation of transcription in eukaryotes. Biochem J (1993) 1.10
Replication and transformation functions of in vitro-generated simian virus 40 large T antigen mutants. J Virol (1986) 1.08
Properties of the DNA-binding domain of the simian virus 40 large T antigen. Mol Cell Biol (1989) 1.08
Changes in the topography of early region transcription during polyoma virus lytic infection. Proc Natl Acad Sci U S A (1982) 1.07
Cessation of reentry of simian virus 40 DNA into replication and its simultaneous appearance in nucleoprotein complexes of the maturation pathway. J Virol (1981) 1.06
Regulation of transcription in vitro from herpes simplex virus genes. J Virol (1986) 1.06
Application of an immunoprecipitation procedure to the study of SV40 tumor antigen interaction with mouse genomic DNA sequences. Nucleic Acids Res (1987) 1.05
Regulatory and structural genes for lysozymes of mice. Genetics (1987) 1.05
Activities of polyomavirus large-T-antigen proteins expressed by mutant genes. J Virol (1984) 1.04
Antigenic structure of simian virus 40 large tumor antigen and association with cellular protein p53 on the surfaces of simian virus 40-infected and -transformed cells. J Virol (1984) 1.04
Expression of viral early functions in rat 3Y1 cells infected with human papovavirus BK. J Virol (1984) 1.04
Phosphorylation and dephosphorylation alter the structure of D2 hybrid T antigen. J Virol (1982) 1.02
Simian virus 40 (SV40) T antigen binds specifically to double-stranded DNA but not to single-stranded DNA or DNA/RNA hybrids containing the SV40 regulatory sequences. J Virol (1988) 1.02
The human DNA-activated protein kinase phosphorylates simian virus 40 T antigen at amino- and carboxy-terminal sites. J Virol (1991) 1.02
Simian virus 40 mutant with transposed T-antigen and VP1 genes. J Virol (1982) 1.02
Transactivation of both early and late simian virus 40 promoters by large tumor antigen does not require nuclear localization of the protein. Proc Natl Acad Sci U S A (1989) 1.02
The SV40 enhancer influences viral late transcription in vitro and in vivo but not on replicating templates. EMBO J (1985) 1.00
Repression of enhancer II activity by a negative regulatory element in the hepatitis B virus genome. J Virol (1994) 0.99
Circular and linear simian virus 40 DNAs differ in recombination. Mol Cell Biol (1985) 0.99
Potential mechanisms of the human polyomavirus JC in neural oncogenesis. J Neuropathol Exp Neurol (2008) 0.98
Functional comparison of PML-type and archetype strains of JC virus. J Virol (1996) 0.98
Oligomerization and origin DNA-binding activity of simian virus 40 large T antigen. J Virol (1987) 0.93
DNA sequence of the leftward junction in the adenovirus-simian virus 40 hybrid Ad2+D2 and determination of the structure of the D2-T antigen. J Virol (1985) 0.92
Mapping the in vivo arrangement of nucleosomes on simian virus 40 chromatin by the photoaddition of radioactive hydroxymethyltrimethylpsoralen. J Virol (1982) 0.90
In vitro transcription of herpes simplex virus genes: identification of a new initiation site and second intervening sequence in the immediate-early RNA-5 gene. J Virol (1985) 0.90
Tissue site-specific enhancer function of the upstream regulatory region of human papillomavirus type 11 in cultured keratinocytes. J Virol (1989) 0.90
Activation of simian virus 40 transcription in vitro by T antigen. J Virol (1992) 0.90
Comeasurement of simian virus 40 early and late promoter activity in HeLa and 293 cells in the presence of T antigen. J Virol (1989) 0.89
Accurate transcription of simian virus 40 chromatin in a HeLa cell extract. J Virol (1982) 0.86
Characterization of a new simian virus 40 mutant, tsA3900, isolated from deletion mutant tsA1499. J Virol (1985) 0.86
Conversion of simian virus 40 DNA to ordered nucleoprotein structures by extracts that direct accurate initiation by eukaryotic RNA polymerase II. Nucleic Acids Res (1982) 0.85
Loss of DNA-binding and new transcriptional trans-activation function in polyomavirus large T-antigen with mutation of zinc finger motif. Nucleic Acids Res (1990) 0.85
Thermally inactivated simian virus 40 tsA58 mutant T antigen cannot initiate viral DNA replication in vitro. J Virol (1990) 0.85
Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08
Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol (1967) 106.91
Complete nucleotide sequence of the Escherichia coli plasmid pBR322. Cold Spring Harb Symp Quant Biol (1979) 43.48
Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange. Proc Natl Acad Sci U S A (1977) 41.76
DNAse footprinting: a simple method for the detection of protein-DNA binding specificity. Nucleic Acids Res (1978) 30.43
Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event. Biochemistry (1970) 26.22
The genome of simian virus 40. Science (1978) 24.46
DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proc Natl Acad Sci U S A (1980) 24.21
Complete nucleotide sequence of SV40 DNA. Nature (1978) 24.07
Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA. Cell (1979) 19.98
Simian virus 40 deoxyribonucleic acid synthesis: the viral replicon. J Virol (1972) 16.59
Regulation of simian virus 40 transcription: sensitive analysis of the RNA species present early in infections by virus or viral DNA. J Virol (1979) 15.69
A control region in the center of the 5S RNA gene directs specific initiation of transcription: I. The 5' border of the region. Cell (1980) 13.19
Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes. Cell (1980) 10.87
The binding site on SV40 DNA for a T antigen-related protein. Cell (1978) 10.58
Regulation of tumor antigen synthesis by simain virus 40 gene A. J Virol (1975) 9.93
Mammalian deoxyribonucleic acid-dependent ribonucleic acid polymerases. I. Purification and properties of an -amanitin-sensitive ribonucleic acid polymerase and stimulatory factors from HeLa and KB cells. J Biol Chem (1973) 8.86
Transcription of Simian virus 40. I. Separation of the strands of SV40 DNA and hybridization of the separated strands to RNA extracted from lytically infected and transformed cells. J Mol Biol (1972) 7.49
Bidirectional replication of Simian Virus 40 DNA. Proc Natl Acad Sci U S A (1972) 6.79
Origin and direction of simian virus 40 deoxyribonucleic acid replication. J Virol (1972) 6.39
Autoregulation of simian virus 40 gene A by T antigen. Proc Natl Acad Sci U S A (1976) 6.38
Expression of early genes of origin-defective mutants of simian virus 40. Proc Natl Acad Sci U S A (1980) 5.33
A map of simian virus 40 transcription sites expressed in productively infected cells. J Mol Biol (1973) 5.02
Protein-DNA interactions at the origin of simian virus 40 DNA replication. Cold Spring Harb Symp Quant Biol (1979) 4.51
Relationship of replication and transcription of Simian Virus 40 DNA. Proc Natl Acad Sci U S A (1973) 4.35
Adenovirus DNA-directed transcription of 5.5S RNA in vitro. Proc Natl Acad Sci U S A (1978) 4.01
Regulation of early and late simian virus 40 transcription: overproduction of early viral RNA in the absence of a functional T-antigen. J Virol (1977) 3.96
Enzymatic activities associated with a purified simian virus 40 T antigen-related protein. Proc Natl Acad Sci U S A (1979) 3.82
Patterns of Simian Virus 40 DNA transcription after acute infection of permissive and nonpermissive cells. Proc Natl Acad Sci U S A (1972) 3.65
Characterization of the autoregulation of simian virus 40 gene A. J Virol (1977) 3.45
Transcription of simian virus 40. 3. Mapping of "early" and "late" species of RNA. Proc Natl Acad Sci U S A (1973) 3.04
The structure and expression of two defective adenovirus 2/simian virus 40 hybrids. J Mol Biol (1978) 2.79
End group labelling of RNA and double stranded DNA by phosphate exchange catalyzed by bacteriophage T4 induced polynucleotide kinase. Biochem Biophys Res Commun (1975) 1.80
Inhibition by -amanitin of simian virus 40-specific ribonucleic acid synthesis in nuclei of infected monkey cells. J Virol (1972) 1.56
Effect of a tsA mutation of simian virus 40 late gene expression: variations between host cell lines. J Virol (1980) 1.37
Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science (1989) 25.68
Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest (2001) 23.21
The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter. Cell (1983) 15.09
Affinity purification of sequence-specific DNA binding proteins. Proc Natl Acad Sci U S A (1986) 14.92
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell (1987) 14.62
Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins. Nature (1985) 14.41
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell (1988) 12.68
Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. Science (1986) 12.58
Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell (1987) 12.30
Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro. Cell (1985) 11.03
The binding site on SV40 DNA for a T antigen-related protein. Cell (1978) 10.58
Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science (1987) 10.25
A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication. Cell (1987) 10.22
Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II. Cell (1983) 8.85
The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain. Cell (1989) 8.60
Mechanism of transcriptional activation by Sp1: evidence for coactivators. Cell (1990) 8.18
Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1. Science (1986) 8.01
Structure and function of a human TAFII250 double bromodomain module. Science (2000) 8.00
Transcriptional selectivity of viral genes in mammalian cells. Cell (1986) 7.95
Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins. Nature (1990) 7.91
Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen. Cell (1987) 7.51
Construction and analysis of simian virus 40 origins defective in tumor antigen binding and DNA replication. Proc Natl Acad Sci U S A (1980) 7.04
Multiple specific contacts between a mammalian transcription factor and its cognate promoters. Nature (1985) 6.77
Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40. Nature (1987) 6.76
A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs. Nature (1988) 6.54
Trinucleotide repeat length instability and age of onset in Huntington's disease. Nat Genet (1993) 6.53
Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers. Science (1989) 6.51
Fos-associated protein p39 is the product of the jun proto-oncogene. Science (1988) 6.34
Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation. Cell (1991) 6.04
Yale studies in ambulatory medical care. V. Determinants of use of hospital emergency services. Am J Public Health Nations Health (1966) 5.98
Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators. Cell (1993) 5.91
Orchestrated response: a symphony of transcription factors for gene control. Genes Dev (2000) 5.86
O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation. Cell (1988) 5.82
Topography of simian virus 40 A protein-DNA complexes: arrangement of pentanucleotide interaction sites at the origin of replication. J Virol (1983) 5.00
Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions. Science (1985) 5.00
Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012. Euro Surveill (2012) 4.96
Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts. Cell (1988) 4.87
Area V5 of the human brain: evidence from a combined study using positron emission tomography and magnetic resonance imaging. Cereb Cortex (1993) 4.79
Functional domains and upstream activation properties of cloned human TATA binding protein. Science (1990) 4.67
SV40 gene expression is modulated by the cooperative binding of T antigen to DNA. Cell (1981) 4.64
Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB. Cell (1993) 4.57
Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism. Genes Dev (1991) 4.54
Protein-DNA interactions at the origin of simian virus 40 DNA replication. Cold Spring Harb Symp Quant Biol (1979) 4.51
Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell (1989) 4.49
Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation. Nature (1993) 4.38
The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell (1994) 4.30
A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation. Proc Natl Acad Sci U S A (1994) 4.27
Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85. Science (1994) 4.24
Transcription from a TATA-less promoter requires a multisubunit TFIID complex. Genes Dev (1991) 4.23
Functional cooperativity between transcription factors UBF1 and SL1 mediates human ribosomal RNA synthesis. Science (1988) 4.17
The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SL1. Cell (1992) 4.11
Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators. Cell (1994) 4.06
GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase. Cell (1990) 4.04
Sp1 binds to promoter sequences and activates herpes simplex virus 'immediate-early' gene transcription in vitro. Nature (1985) 3.99
Transcriptional coactivator complexes. Annu Rev Biochem (2001) 3.97
Enzymatic activities associated with a purified simian virus 40 T antigen-related protein. Proc Natl Acad Sci U S A (1979) 3.82
DNA template and activator-coactivator requirements for transcriptional synergism by Drosophila bicoid. Science (1995) 3.79
Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex. Genes Dev (1991) 3.77
p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60. Science (1995) 3.74
Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements. Genes Dev (1988) 3.72
Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II. Cell (1994) 3.61
TAFs mediate transcriptional activation and promoter selectivity. Trends Biochem Sci (1996) 3.59
In-vivo measurement of activated microglia in dementia. Lancet (2001) 3.51
Analysis of the DNA-binding and activation properties of the human transcription factor AP-2. Genes Dev (1991) 3.50
Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription. Cell (1991) 3.46
Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis. Genes Dev (1991) 3.46
Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity. Genes Dev (1990) 3.44
TAFII250-dependent transcription of cyclin A is directed by ATF activator proteins. Genes Dev (1997) 3.40
A novel strategy for constructing clustered point mutations. Nucleic Acids Res (1985) 3.39
Patient-related barriers to management of cancer pain. Pain (1993) 3.33
Composite co-activator ARC mediates chromatin-directed transcriptional activation. Nature (1999) 3.32
Hormonal impact of the 17alpha-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer. Br J Cancer (2004) 3.32
Distinct regions of Sp1 modulate DNA binding and transcriptional activation. Science (1988) 3.23
Recording, retrieval and review of medical data by physician-computer interaction. N Engl J Med (1970) 3.23
T-antigen-DNA polymerase alpha complex implicated in simian virus 40 DNA replication. Mol Cell Biol (1986) 3.22
Elevating clinical licensing examinations to professional testing standards. N Y State Dent J (1998) 3.20
Transcription factor Sp1 recognizes a DNA sequence in the mouse dihydrofolate reductase promoter. Nature (1986) 3.18
DNA looping between sites for transcriptional activation: self-association of DNA-bound Sp1. Genes Dev (1991) 3.10
Biochemical activities of T-antigen proteins encoded by simian virus 40 A gene deletion mutants. Mol Cell Biol (1983) 3.06
TAFs revisited: more data reveal new twists and confirm old ideas. Gene (2000) 3.02
Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II. Cell (1995) 3.01
Biochemical analysis of transcriptional activation by Jun: differential activity of c- and v-Jun. Cell (1989) 2.93
Transcription of herpes simplex virus tk sequences under the control of wild-type and mutant human RNA polymerase I promoters. Mol Cell Biol (1985) 2.92
Characterization of Drosophila transcription factors that activate the tandem promoters of the alcohol dehydrogenase gene. Cell (1985) 2.86
Control of c-Jun activity by interaction of a cell-specific inhibitor with regulatory domain delta: differences between v- and c-Jun. Cell (1990) 2.86
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity. Brain (2000) 2.84
The Huntington's disease candidate region exhibits many different haplotypes. Nat Genet (1992) 2.84
Use of monoclonal antibodies as probes of simian virus 40 T antigen ATPase activity. J Biol Chem (1981) 2.77
Antibody directed against Bacillus subtilis rho factor purified by sodium dodecyl sulfate slab gel electrophoresis. Effect on transcription by RNA polymerase in crude extracts of vegetative and sporulating cells. J Biol Chem (1975) 2.73
Selectivity of chromatin-remodelling cofactors for ligand-activated transcription. Nature (2002) 2.66
Purification and characterization of a transcription factor that confers promoter specificity to human RNA polymerase I. Mol Cell Biol (1985) 2.65
The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1. Nature (1999) 2.61
Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development. Science (2001) 2.59
Essential contact residues within SV40 large T antigen binding sites I and II identified by alkylation-interference. Cell (1984) 2.59
Transcription properties of a cell type-specific TATA-binding protein, TRF. Cell (1997) 2.57
Biological activity of purified simian virus 40 T antigen proteins. Proc Natl Acad Sci U S A (1978) 2.54
Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro. Nature (1988) 2.54
Drosophila TAFII150: similarity to yeast gene TSM-1 and specific binding to core promoter DNA. Science (1994) 2.48
TBP-TAF complexes: selectivity factors for eukaryotic transcription. Curr Opin Cell Biol (1994) 2.46