Modification of the catalytic subunit of bovine heart cAMP-dependent protein kinase with affinity labels related to peptide substrates.

PubWeight™: 1.04‹?› | Rank: Top 15%

🔗 View Article (PMID 6286662)

Published in J Biol Chem on September 25, 1982


H N Bramson, N Thomas, R Matsueda, N C Nelson, S S Taylor, E T Kaiser

Articles by these authors

Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science (1991) 13.85

Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science (1991) 9.99

Identification of a signal for rapid export of proteins from the nucleus. Cell (1995) 9.92

Human gene mutation database-a biomedical information and research resource. Hum Mutat (2000) 6.87

Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomised trial. Lancet (2009) 6.83

Matching using estimated propensity scores: relating theory to practice. Biometrics (1996) 6.73

Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity. Science (2011) 4.72

Fluorescence ratio imaging of cyclic AMP in single cells. Nature (1991) 4.45

Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinases in vivo and in vitro. J Biol Chem (1984) 4.20

Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy. Nature (1986) 4.13

Direct evidence that oncogenic tyrosine kinases and cyclic AMP-dependent protein kinase have homologous ATP-binding sites. Nature (1984) 3.91

X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein. Nat Genet (1996) 3.90

Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor. Biochemistry (1993) 3.88

Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering. Proc Natl Acad Sci U S A (2001) 3.77

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. Mol Cell (1999) 3.46

Dynamics of cAMP-dependent protein kinase. Chem Rev (2001) 3.18

Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains. Science (1995) 3.18

Portal and peripheral vein immunoreactive insulin concentrations before and after glucose infusion. Diabetes (1970) 3.12

A protein that activates expression of a multidrug efflux transporter upon binding the transporter substrates. J Biol Chem (1994) 3.08

Platelet factor 4 is chemotactic for neutrophils and monocytes. Proc Natl Acad Sci U S A (1981) 3.03

Assay formats involving acridinium-ester-labeled DNA probes. Clin Chem (1989) 2.93

Amphiphilic secondary structure: design of peptide hormones. Science (1984) 2.71

A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein. J Cell Biol (1999) 2.69

2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor. Acta Crystallogr D Biol Crystallogr (1993) 2.66

cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransfer. Protein Sci (1994) 2.62

Protein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria. Proc Natl Acad Sci U S A (1990) 2.61

Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration. J Med Genet (2005) 2.56

Interpreting hospital mortality data. The role of clinical risk adjustment. JAMA (1989) 2.53

Limb-salvage treatment versus amputation for osteosarcoma of the distal end of the femur. J Bone Joint Surg Am (1986) 2.49

Affinity labeling of cAMP-dependent protein kinase with p-fluorosulfonylbenzoyl adenosine. Covalent modification of lysine 71. J Biol Chem (1981) 2.48

Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations. Protein Sci (1993) 2.44

A genetically encoded, fluorescent indicator for cyclic AMP in living cells. Nat Cell Biol (2000) 2.34

Treatment of acute myocardial infarction with anisoylated plasminogen streptokinase activator complex. Br Med J (Clin Res Ed) (1986) 2.33

Primary structure of Torpedo californica acetylcholinesterase deduced from its cDNA sequence. Nature (1986) 2.32

D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele. Pharmacogenetics (1997) 2.28

Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated. J Bacteriol (1995) 2.26

Secondary structures of proteins and peptides in amphiphilic environments. (A review). Proc Natl Acad Sci U S A (1983) 2.26

An absence of cutaneous neurofibromas associated with a 3-bp inframe deletion in exon 17 of the NF1 gene (c.2970-2972 delAAT): evidence of a clinically significant NF1 genotype-phenotype correlation. Am J Hum Genet (2006) 2.23

In vitro differentiation of Trypanosoma cruzi under chemically defined conditions. Mol Biochem Parasitol (1985) 2.20

Predicting hospital-associated mortality for Medicare patients. A method for patients with stroke, pneumonia, acute myocardial infarction, and congestive heart failure. JAMA (1989) 2.19

Aneuploid colon cancer cells have a robust spindle checkpoint. EMBO Rep (2001) 2.12

Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits. J Biol Chem (1997) 2.10

Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase. Proc Natl Acad Sci U S A (1998) 2.09

Kinetics and mechanism of hemolysis induced by melittin and by a synthetic melittin analogue. Biophys J (1982) 2.03

Structural adaptations of lactate dehydrogenase isozymes. Proc Natl Acad Sci U S A (1977) 1.88

Structure-function relationships in lactate dehydrogenase. Proc Natl Acad Sci U S A (1973) 1.87

The protein kinase resource. Trends Biochem Sci (1997) 1.85

Expression of the catalytic subunit of cAMP-dependent protein kinase in Escherichia coli. J Biol Chem (1989) 1.85

The interaction of hemoglobin with the cytoplasmic domain of band 3 of the human erythrocyte membrane. J Biol Chem (1984) 1.83

Advantages of 2'-O-methyl oligoribonucleotide probes for detecting RNA targets. Nucleic Acids Res (1998) 1.82

Climate change and the integrity of science. Science (2010) 1.80

D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain. Proc Natl Acad Sci U S A (1997) 1.79

Movement of the free catalytic subunit of cAMP-dependent protein kinase into and out of the nucleus can be explained by diffusion. Mol Biol Cell (1993) 1.71

A closer look at water-related geologic activity on Mars. Science (2007) 1.71

Mineralization of linear alkylbenzene sulfonate by a four-member aerobic bacterial consortium. Appl Environ Microbiol (1991) 1.68

Retracted Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors. Science (2001) 1.67

Identification of a mutant human insulin predicted to contain a serine-for-phenylalanine substitution. Proc Natl Acad Sci U S A (1983) 1.67

Energetic limits of phosphotransfer in the catalytic subunit of cAMP-dependent protein kinase as measured by viscosity experiments. Biochemistry (1992) 1.64

Peptides with affinity for membranes. Annu Rev Biophys Biophys Chem (1987) 1.63

Long-read sequence analysis of the MECP2 gene in Rett syndrome patients: correlation of disease severity with mutation type and location. Hum Mol Genet (2000) 1.61

Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit. Structure (2001) 1.59

Optical observations of comet Hale-Bopp (C/1995 O1) at large heliocentric distances before perihelion. Science (1997) 1.58

Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates. J Biol Chem (1990) 1.57

Role of the glycine triad in the ATP-binding site of cAMP-dependent protein kinase. J Biol Chem (1997) 1.55

Phosphorylation modulates catalytic function and regulation in the cAMP-dependent protein kinase. Biochemistry (1995) 1.55

Phosphorylation of histones 1 and 3 and nonhistone high mobility group 14 by an endogenous kinase in HeLa metaphase chromosomes. J Biol Chem (1982) 1.54

Structural features that specify tyrosine kinase activity deduced from homology modeling of the epidermal growth factor receptor. Proc Natl Acad Sci U S A (1993) 1.53

Expression of the catalytic subunit of cAMP-dependent protein kinase in Escherichia coli: multiple isozymes reflect different phosphorylation states. Protein Eng (1993) 1.52

Design and characterization of peptides with amphiphilic beta-strand structures. J Cell Biochem (1985) 1.51

A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility. Structure (1997) 1.51

The mechanism of activation of lecithin:cholesterol acyltransferase by apolipoprotein A-I and an amphiphilic peptide. J Biol Chem (1980) 1.50

Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine. Biochemistry (1997) 1.50

Active site mutations define the pathway for the cooperative activation of cAMP-dependent protein kinase. Biochemistry (1996) 1.48

Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution. Brain (1999) 1.48

Domain movements in protein kinases. Curr Opin Struct Biol (1994) 1.47

NH2-Terminal targeting motifs direct dual specificity A-kinase-anchoring protein 1 (D-AKAP1) to either mitochondria or endoplasmic reticulum. J Cell Biol (1999) 1.46

Microbial DNA profiling by multiplex terminal restriction fragment length polymorphism for forensic comparison of soil and the influence of sample condition. J Appl Microbiol (2008) 1.45

The dental caries experience of 5-year-old children in Great Britain (2005/6). Surveys co-ordinated by the British Association for the study of community dentistry. Community Dent Health (2007) 1.43

Heat-stable inhibitors of cAMP-dependent protein kinase carry a nuclear export signal. J Biol Chem (1994) 1.43

N-myristylation of the catalytic subunit of cAMP-dependent protein kinase conveys structural stability. J Biol Chem (1993) 1.42

Profile of the disulfide bonds in acetylcholinesterase. J Biol Chem (1986) 1.42

Ribitol dehydrogenase from Klebsiella aerogenes. Purification and subunit structure. Biochem J (1974) 1.39

Measurement of quality of life for elderly people on dialysis. Br J Nurs (1992) 1.38

Serum protein electrophoresis in 147 dogs. Vet Rec (2011) 1.38

Systematic mutational analysis of cAMP-dependent protein kinase identifies unregulated catalytic subunits and defines regions important for the recognition of the regulatory subunit. J Biol Chem (1992) 1.37

The catalytic subunit of cAMP-dependent protein kinase: prototype for an extended network of communication. Prog Biophys Mol Biol (1999) 1.36

Structural comparisons of cAMP-dependent protein kinases I and II from porcine skeletal muscle. J Biol Chem (1979) 1.36

Associations of fat distribution and obesity with hypertension in a bi-ethnic population: the ARIC study. Atherosclerosis Risk in Communities Study. Obes Res (2000) 1.35

Dissecting cAMP binding domain A in the RIalpha subunit of cAMP-dependent protein kinase. Distinct subsites for recognition of cAMP and the catalytic subunit. J Biol Chem (1998) 1.34

Idealization of the hydrophobic segment of the alkaline phosphatase signal peptide. Nature (1986) 1.34

Rain, winds and haze during the Huygens probe's descent to Titan's surface. Nature (2005) 1.34

Physiological inhibitors of the catalytic subunit of cAMP-dependent protein kinase: effect of MgATP on protein-protein interactions. Biochemistry (1993) 1.33

SPRED1 mutations (Legius syndrome): another clinically useful genotype for dissecting the neurofibromatosis type 1 phenotype. J Med Genet (2009) 1.32

600 ps molecular dynamics reveals stable substructures and flexible hinge points in cAMP dependent protein kinase. Biopolymers (1999) 1.32

Safety and efficacy of oral entecavir given for 28 days in patients with chronic hepatitis B virus infection. Hepatology (2001) 1.32

Structural basis of the intrasteric regulation of myosin light chain kinases. Science (1992) 1.31

Accuracy of radiographer plain radiograph reporting in clinical practice: a meta-analysis. Clin Radiol (2005) 1.31

Dissection of the nucleotide and metal-phosphate binding sites in cAMP-dependent protein kinase. Biochemistry (1999) 1.29

Work site group meetings and the effectiveness of a televised smoking cessation intervention. Am J Community Psychol (1987) 1.29