Published in Virology on August 01, 1983
The alphaviruses: gene expression, replication, and evolution. Microbiol Rev (1994) 16.68
N-terminal domains of putative helicases of flavi- and pestiviruses may be serine proteases. Nucleic Acids Res (1989) 4.27
Nucleocapsid and glycoprotein organization in an enveloped virus. Cell (1995) 3.66
Western equine encephalitis virus is a recombinant virus. Proc Natl Acad Sci U S A (1988) 3.19
pH-induced alterations in the fusogenic spike protein of Semliki Forest virus. J Cell Biol (1985) 2.98
Complete nucleotide sequence of the nonstructural protein genes of Semliki Forest virus. Nucleic Acids Res (1986) 2.56
Membrane fusion process of Semliki Forest virus. I: Low pH-induced rearrangement in spike protein quaternary structure precedes virus penetration into cells. J Cell Biol (1992) 2.51
Mutagenesis of the 3' nontranslated region of Sindbis virus RNA. J Virol (1990) 2.42
Oligomers of the cytoplasmic domain of the p62/E2 membrane protein of Semliki Forest virus bind to the nucleocapsid in vitro. J Virol (1990) 2.33
Mutagenesis of the putative fusion domain of the Semliki Forest virus spike protein. J Virol (1991) 2.30
Sequence analysis of three Sindbis virus mutants temperature-sensitive in the capsid protein autoprotease. Proc Natl Acad Sci U S A (1985) 2.18
Internally located cleavable signal sequences direct the formation of Semliki Forest virus membrane proteins from a polyprotein precursor. J Virol (1991) 2.17
A tyrosine-based motif in the cytoplasmic domain of the alphavirus envelope protein is essential for budding. EMBO J (1994) 2.09
Fusion function of the Semliki Forest virus spike is activated by proteolytic cleavage of the envelope glycoprotein precursor p62. J Virol (1990) 2.00
The transmembrane domain in viral fusion: essential role for a conserved glycine residue in vesicular stomatitis virus G protein. Proc Natl Acad Sci U S A (1998) 1.99
Processing of the Semliki Forest virus structural polyprotein: role of the capsid protease. J Virol (1987) 1.96
Identification of a region in the Sindbis virus nucleocapsid protein that is involved in specificity of RNA encapsidation. J Virol (1996) 1.96
Site-directed mutations in the Sindbis virus E2 glycoprotein identify palmitoylation sites and affect virus budding. J Virol (1993) 1.82
A single nucleotide change in the E2 glycoprotein gene of Sindbis virus affects penetration rate in cell culture and virulence in neonatal mice. Proc Natl Acad Sci U S A (1986) 1.82
Characterization of Ross River virus tropism and virus-induced inflammation in a mouse model of viral arthritis and myositis. J Virol (2006) 1.73
Function of Semliki Forest virus E3 peptide in virus assembly: replacement of E3 with an artificial signal peptide abolishes spike heterodimerization and surface expression of E1. J Virol (1990) 1.57
In vitro assembly of alphavirus cores by using nucleocapsid protein expressed in Escherichia coli. J Virol (1999) 1.54
The signal sequence of the p62 protein of Semliki Forest virus is involved in initiation but not in completing chain translocation. J Cell Biol (1990) 1.38
Antibody-selected variation and reversion in Sindbis virus neutralization epitopes. J Virol (1986) 1.35
Spike protein oligomerization control of Semliki Forest virus fusion. J Virol (1990) 1.34
A mutant CHO-K1 strain with resistance to Pseudomonas exotoxin A and alphaviruses fails to cleave Sindbis virus glycoprotein PE2. J Virol (1991) 1.33
Structural localization of the E3 glycoprotein in attenuated Sindbis virus mutants. J Virol (1998) 1.30
The cytoplasmic domain of alphavirus E2 glycoprotein contains a short linear recognition signal required for viral budding. EMBO J (1991) 1.27
Preformed cytoplasmic nucleocapsids are not necessary for alphavirus budding. EMBO J (1996) 1.19
Complement contributes to inflammatory tissue destruction in a mouse model of Ross River virus-induced disease. J Virol (2007) 1.17
Lethality of PE2 incorporation into Sindbis virus can be suppressed by second-site mutations in E3 and E2. J Virol (1994) 1.14
Involvement of the molecular chaperone BiP in maturation of Sindbis virus envelope glycoproteins. J Virol (1995) 1.13
The amino-terminal residue of Sindbis virus glycoprotein E2 influences virus maturation, specific infectivity for BHK cells, and virulence in mice. J Virol (1994) 1.05
Semliki Forest virus E2 envelope epitopes induce a nonneutralizing humoral response which protects mice against lethal challenge. J Virol (1989) 1.04
Complement receptor 3 promotes severe ross river virus-induced disease. J Virol (2008) 1.04
An evolutionary tree relating eight alphaviruses, based on amino-terminal sequences of their glycoproteins. Proc Natl Acad Sci U S A (1984) 0.93
Entry kinetics and mouse virulence of Ross River virus mutants altered in neutralization epitopes. J Virol (1996) 0.83
Attenuating mutations in nsP1 reveal tissue-specific mechanisms for control of Ross River virus infection. J Virol (2014) 0.80
A tyrosine-to-histidine switch at position 18 of the Ross River virus E2 glycoprotein is a determinant of virus fitness in disparate hosts. J Virol (2013) 0.80
CD8+ T cells control Ross River virus infection in musculoskeletal tissues of infected mice. J Immunol (2014) 0.77
Myeloid Cell Arg1 Inhibits Control of Arthritogenic Alphavirus Infection by Suppressing Antiviral T Cells. PLoS Pathog (2015) 0.77
The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites. Proc Natl Acad Sci U S A (1974) 62.91
A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature (2001) 42.18
Determinant of cistron specificity in bacterial ribosomes. Nature (1975) 19.71
Efficient initiation of HCV RNA replication in cell culture. Science (2000) 15.12
Flavivirus genome organization, expression, and replication. Annu Rev Microbiol (1990) 14.20
Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution. Science (1985) 8.54
Expression and identification of hepatitis C virus polyprotein cleavage products. J Virol (1993) 8.47
Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA. Science (1997) 7.53
The DNA sequence and comparative analysis of human chromosome 20. Nature (2002) 7.40
Complete nucleotide sequence of the genomic RNA of Sindbis virus. Virology (1984) 6.60
Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. J Virol (1993) 6.36
Denaturation of RNA with dimethyl sulfoxide. Biopolymers (1968) 6.17
Nucleotide sequence of the 26S mRNA of Sindbis virus and deduced sequence of the encoded virus structural proteins. Proc Natl Acad Sci U S A (1981) 6.08
Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivo. J Virol (2000) 5.26
Overview of hepatitis C virus genome structure, polyprotein processing, and protein properties. Curr Top Microbiol Immunol (2000) 5.17
Sindbis virus: an efficient, broad host range vector for gene expression in animal cells. Science (1989) 4.84
Nucleotide sequence of dengue 2 RNA and comparison of the encoded proteins with those of other flaviviruses. Virology (1988) 4.78
The DNA sequence and analysis of human chromosome 6. Nature (2003) 4.75
Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA. J Virol (1996) 4.59
Identification of the membrane protein and "core" protein of Sindbis virus. Proc Natl Acad Sci U S A (1968) 4.52
Sindbis virus infection of chick and hamster cells: synthesis of virus-specific proteins. Virology (1969) 4.38
A second hepatitis C virus-encoded proteinase. Proc Natl Acad Sci U S A (1993) 4.30
Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis viruses. J Virol (1994) 4.21
Sindbis virus expression vectors: packaging of RNA replicons by using defective helper RNAs. J Virol (1993) 4.19
trans-Complementation of yellow fever virus NS1 reveals a role in early RNA replication. J Virol (1997) 4.17
Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein. Proc Natl Acad Sci U S A (1990) 4.12
Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide. Cell (1996) 4.12
Molecular basis of Sindbis virus neurovirulence in mice. J Virol (1988) 3.90
Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini. J Virol (1994) 3.61
Neutralizing antibody response during acute and chronic hepatitis C virus infection. Proc Natl Acad Sci U S A (2004) 3.57
Terminal-sequence analysis of bacterial ribosomal RNA. Correlation between the 3'-terminal-polypyrimidine sequence of 16-S RNA and translational specificity of the ribosome. Eur J Biochem (1975) 3.55
Sindbis virus proteins nsP1 and nsP2 contain homology to nonstructural proteins from several RNA plant viruses. J Virol (1985) 3.51
In vitro processing of dengue virus type 2 nonstructural proteins NS2A, NS2B, and NS3. J Virol (1990) 3.50
Processing of the yellow fever virus nonstructural polyprotein: a catalytically active NS3 proteinase domain and NS2B are required for cleavages at dibasic sites. J Virol (1991) 3.41
Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes. J Virol (1993) 3.37
Processing the nonstructural polyproteins of sindbis virus: nonstructural proteinase is in the C-terminal half of nsP2 and functions both in cis and in trans. J Virol (1989) 3.30
Conserved elements in the 3' untranslated region of flavivirus RNAs and potential cyclization sequences. J Mol Biol (1987) 3.30
The hepatitis C virus nonstructural protein 4B is an integral endoplasmic reticulum membrane protein. Virology (2001) 3.25
Western equine encephalitis virus is a recombinant virus. Proc Natl Acad Sci U S A (1988) 3.19
Polypeptide requirements for assembly of functional Sindbis virus replication complexes: a model for the temporal regulation of minus- and plus-strand RNA synthesis. EMBO J (1994) 3.00
An SNP map of human chromosome 22. Nature (2000) 2.99
Translation of Sindbis virus 26 S RNA and 49 S RNA in lysates of rabbit reticulocytes. J Mol Biol (1974) 2.97
Association of sindbis virion glycoproteins and their precursors. J Mol Biol (1982) 2.95
Mapping of RNA- temperature-sensitive mutants of Sindbis virus: complementation group F mutants have lesions in nsP4. J Virol (1989) 2.94
Sequence coding for the alphavirus nonstructural proteins is interrupted by an opal termination codon. Proc Natl Acad Sci U S A (1983) 2.94
Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines. J Virol (2000) 2.89
Replication of Sindbis virus. II. Multiple forms of double-stranded RNA isolated from infected cells. J Mol Biol (1972) 2.88
Yellow fever virus proteins NS2A, NS2B, and NS4B: identification and partial N-terminal amino acid sequence analysis. Virology (1989) 2.87
Formation of native hepatitis C virus glycoprotein complexes. J Virol (1997) 2.87
Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation. Proc Natl Acad Sci U S A (1992) 2.86
Processing the nonstructural polyproteins of Sindbis virus: study of the kinetics in vivo by using monospecific antibodies. J Virol (1988) 2.85
Evolutionary relationships and systematics of the alphaviruses. J Virol (2001) 2.84
Processing of the envelope glycoproteins of pestiviruses. J Virol (1993) 2.79
Mapping of RNA- temperature-sensitive mutants of Sindbis virus: assignment of complementation groups A, B, and G to nonstructural proteins. J Virol (1989) 2.78
Sequence studies of several alphavirus genomic RNAs in the region containing the start of the subgenomic RNA. Proc Natl Acad Sci U S A (1982) 2.77
Glycopeptides of the membrane glycoprotein of Sindbis virus. J Mol Biol (1970) 2.75
HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release. J Clin Invest (1995) 2.66
Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics. J Virol (1994) 2.64
Association of the Sindbis virus RNA methyltransferase activity with the nonstructural protein nsP1. Virology (1989) 2.64
Primary structure of the cleavage site associated with trypsin enhancement of rotavirus SA11 infectivity. Virology (1985) 2.63
Mutants of sindbis virus. I. Isolation and partial characterization of 89 new temperature-sensitive mutants. Virology (1976) 2.60
Mutagenesis of the in-frame opal termination codon preceding nsP4 of Sindbis virus: studies of translational readthrough and its effect on virus replication. J Virol (1989) 2.59
Replication of Sindbis virus. I. Relative size and genetic content of 26 s and 49 s RNA. J Mol Biol (1972) 2.59
Cleavage-site preferences of Sindbis virus polyproteins containing the non-structural proteinase. Evidence for temporal regulation of polyprotein processing in vivo. EMBO J (1990) 2.57
Infectious RNA transcripts from Ross River virus cDNA clones and the construction and characterization of defined chimeras with Sindbis virus. Virology (1991) 2.57
Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site. J Virol (1993) 2.56
Occurrence of heat-dissociable ribosomal RNA in insects: the presence of three polynucleotide chains in 26 S RNA from cultured Aedes aegypti cells. J Mol Biol (1973) 2.55
Hepatitis C virus glycoprotein folding: disulfide bond formation and association with calnexin. J Virol (1996) 2.53
Identical 3'-terminal octanucleotide sequence in 18S ribosomal ribonucleic acid from different eukaryotes. A proposed role for this sequence in the recognition of terminator codons. Biochem J (1974) 2.52
Sindbis virus RNA polymerase is degraded by the N-end rule pathway. Proc Natl Acad Sci U S A (1991) 2.52
Production of yellow fever virus proteins in infected cells: identification of discrete polyprotein species and analysis of cleavage kinetics using region-specific polyclonal antisera. Virology (1990) 2.50
Selection of RNA replicons capable of persistent noncytopathic replication in mammalian cells. J Virol (1999) 2.49
Nucleocapsid-glycoprotein interactions required for assembly of alphaviruses. J Virol (1994) 2.47
Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients. J Virol (1996) 2.47
Determinants for membrane association of the hepatitis C virus RNA-dependent RNA polymerase. J Biol Chem (2001) 2.45
Carbohydrate content of the membrane protein of Sindbis virus. J Mol Biol (1970) 2.45
High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells. J Virol (1992) 2.44
Genetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function. J Virol (1999) 2.44
Noncytopathic Sindbis virus RNA vectors for heterologous gene expression. Proc Natl Acad Sci U S A (1998) 2.44
Mutagenesis of the 3' nontranslated region of Sindbis virus RNA. J Virol (1990) 2.42
Phosphorylation of the hepatitis C virus NS5A protein in vitro and in vivo: properties of the NS5A-associated kinase. J Virol (1997) 2.39
Synthesis, cleavage and sequence analysis of DNA complementary to the 26 S messenger RNA of Sindbis virus. J Mol Biol (1981) 2.38
Dengue 2 virus NS2B and NS3 form a stable complex that can cleave NS3 within the helicase domain. Virology (1993) 2.34
Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules. J Virol (1995) 2.34
Secondary structure determination of the conserved 98-base sequence at the 3' terminus of hepatitis C virus genome RNA. J Virol (1997) 2.30