Published in J Mol Cell Cardiol on November 01, 1983
Dissecting lidocaine action: diethylamide and phenol mimic separate modes of lidocaine block of sodium channels from heart and skeletal muscle. Biophys J (1993) 1.40
Amine blockers of the cytoplasmic mouth of sodium channels: a small structural change can abolish voltage dependence. Biophys J (1994) 0.94
Dual actions of procainamide on batrachotoxin-activated sodium channels: open channel block and prevention of inactivation. Biophys J (1993) 0.89
Electrophysiological effects of the combination of mexiletine and flecainide in guinea-pig ventricular fibres. Br J Pharmacol (1991) 0.82
Characterization of concentration- and use-dependent effects of quinidine from conduction delay and declining conduction velocity in canine Purkinje fibers. J Clin Invest (1989) 0.81
Electrophysiological effects of CRE-1087 in guinea-pig ventricular muscles. Br J Pharmacol (1992) 0.81
Mechanism of frequency-dependent inhibition of sodium currents in frog myelinated nerve by the lidocaine derivative GEA. J Pharmacol Exp Ther (1975) 5.07
Structure-activity relations for frequency-dependent sodium channel block in nerve by local anesthetics. J Pharmacol Exp Ther (1980) 1.63
Comparative actions of mexiletine on sodium channels in nerve, skeletal and cardiac muscle. Eur J Pharmacol (1981) 1.33
The rates of interaction of local anesthetics with sodium channels in nerve. J Pharmacol Exp Ther (1978) 1.20
Interval-dependent effects of small antiarrhythmic drugs on excitability of guinea-pig myocardium. J Mol Cell Cardiol (1980) 1.12
Fast frequency-dependent block of action potential upstroke in rabbit atrium by small local anesthetics. Life Sci (1979) 1.03
Anesthetics: molecular correlates of voltage- and frequency-dependent sodium channel block in nerve. J Pharmacol Exp Ther (1979) 1.01
Design of a multi-point laser scanned optical monitor of cardiac action potential propagation: application to microreentry in guinea pig atrium. Ann Biomed Eng (1987) 0.99
Use-dependent block of single sodium channels by lidocaine in guinea pig ventricular myocytes. Biophys J (1989) 0.95
Quantitative structure/activity relations based on use-dependent block and repriming kinetics in myocardium. J Mol Cell Cardiol (1987) 0.94
Voltage-sensitive dyes. Discerning contraction and electrical signals in myocardium. Biophys J (1982) 0.92
Modeling ion channel blockade at guarded binding sites: application to tertiary drugs. Am J Physiol (1986) 0.92
Extracellular pH selectively modulates recovery from sodium inactivation in frog myelinated nerve. Biophys J (1979) 0.92
Reentrant tachycardia in a thin layer of ventricular subepicardium: effects of d-sotalol and lidocaine. J Cardiovasc Pharmacol (1990) 0.83
Epileptogenesis in neocortical slices. Brain Res (1977) 0.82
Frequency-dependent conduction block: the role of nerve impulse pattern in local anesthetic potency. Anesthesiology (1978) 0.82
Significance of bicarbonate for antiarrhythmic drug action. J Mol Cell Cardiol (1981) 0.81
Size-dependent kinetics associated with drug block of sodium current. Biophys J (1984) 0.80
Unit responses recorded from cervical spinal cord of awake monkey. Brain Res (1973) 0.79
Extended moment analysis for binomial parameters of transmitter release. J Theor Biol (1978) 0.79
Imipramine affects autonomic control of sinoatrial rate in isolated right atrial preparations. J Pharmacol Exp Ther (1979) 0.79
Sodium ions affect adrenergic control of sinoatrial rate. J Mol Cell Cardiol (1979) 0.79
Gate-dependent blockade of sodium channels by phenothiazine derivatives: structure-activity relationships. Mol Pharmacol (1992) 0.79
Modulated anticonvulsant block of sodium channels in nerve and muscle. Eur J Pharmacol (1983) 0.77
Importance of electrogenic sodium pump in normal and overdriven sinoatrial pacemaker. J Mol Cell Cardiol (1979) 0.77
Prostaglandins and pacemaker activity in isolated guinea pig SA node. Prostaglandins (1978) 0.76
New modes of nerve block. Anesthesiology (1991) 0.75
Slow sodium channel inactivation and the modulated receptor hypothesis: application to phenobarbital. Biochim Biophys Acta (1981) 0.75
Relationship between excitability block and negative inotropic actions of antiarrhythmic drugs. Proc West Pharmacol Soc (1984) 0.75
Effects of imipramine on spontaneous rate and chronotropic responses to transmural stimulation in isolated right atrial preparations. Proc West Pharmacol Soc (1978) 0.75
Mechanisms of quinidine-induced depression of maximum upstroke velocity in ovine cardiac Purkinje fibers. Circ Res (1983) 0.75
Rate selective block of nerve and myocardial excitability by imipramine. Proc West Pharmacol Soc (1980) 0.75
d-Sotalol has opposite effects from encainide and propafenone on the proportion of episodes of ventricular tachycardia that are sustained in an experimental substrate for reentry. J Cardiovasc Pharmacol (1992) 0.75
Depressant effects of drugs used in myotonia therapy. Proc West Pharmacol Soc (1982) 0.75