Published in J Comp Neurol on June 20, 1984
Senile plaques, amyloid beta-protein, and acetylcholinesterase fibres: laminar distributions in Alzheimer's disease striate cortex. Acta Neuropathol (1992) 0.93
Histological features of layers and sublayers in cortical visual areas V1 and V2 of chimpanzees, macaque monkeys, and humans. Eye Brain (2014) 0.78
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron (1997) 6.16
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron (1995) 6.03
Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. Science (1982) 5.63
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron (1996) 5.30
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron (1996) 5.14
BACE1 is the major beta-secretase for generation of Abeta peptides by neurons. Nat Neurosci (2001) 4.54
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron (1997) 4.49
Alzheimer's disease: a disorder of cortical cholinergic innervation. Science (1983) 4.40
Control of acetylcholine receptors in skeletal muscle. Physiol Rev (1979) 4.28
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin. Hum Mol Genet (1999) 4.06
Acetylcholine receptor turnover in membranes of developing muscle fibers. J Cell Biol (1975) 4.02
Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity. Proc Natl Acad Sci U S A (1994) 3.36
Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia. Proc Natl Acad Sci U S A (1997) 3.26
Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease. Science (1987) 3.23
Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis. Ann Neurol (1981) 3.18
A vector for expressing foreign genes in the brains and hearts of transgenic mice. Genet Anal (1996) 3.18
Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm. Nature (1997) 3.14
Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport. Proc Natl Acad Sci U S A (1990) 3.13
Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing. Science (1990) 3.10
Acetylcholine receptors: number and distribution at neuromuscular junctions in rat diaphragm. Science (1972) 3.03
Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats. Am J Hum Genet (1996) 2.88
Neuromuscular junction in myasthenia gravis: decreased acetylcholine receptors. Science (1973) 2.86
Calf and pea histone IV. II. The complete amino acid sequence of calf thymus histone IV; presence of epsilon-N-acetyllysine. J Biol Chem (1969) 2.83
Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies. J Neurosci (1991) 2.73
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathology confirmation of the clinical diagnosis of Alzheimer's disease. Neurology (1995) 2.69
Acetylcholine receptors. Distribution and extrajunctional density in rat diaphragm after denervation correlated with acetylcholine sensitivity. J Gen Physiol (1972) 2.66
Cycling of the integral membrane glycoprotein, LEP100, between plasma membrane and lysosomes: kinetic and morphological analysis. Cell (1987) 2.57
Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR. Genomics (1992) 2.55
Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues. Neurobiol Dis (2001) 2.53
Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease. J Neuropathol Exp Neurol (1997) 2.43
Most cases of dementia with hippocampal sclerosis may represent frontotemporal dementia. Neurology (2004) 2.42
Chick myotendinous antigen. I. A monoclonal antibody as a marker for tendon and muscle morphogenesis. J Cell Biol (1984) 2.39
Neurofilament gene expression: a major determinant of axonal caliber. Proc Natl Acad Sci U S A (1987) 2.36
VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity. Proc Natl Acad Sci U S A (1997) 2.34
Acetycholine receptor production and incorporation into membranes of developing muscle fibers. Dev Biol (1973) 2.28
Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice. Proc Natl Acad Sci U S A (2008) 2.25
Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors. J Biol Chem (1997) 2.24
Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice. Proc Natl Acad Sci U S A (1998) 2.22
Botulinum toxin: mechanism of presynaptic blockade. Science (1976) 2.19
Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc Natl Acad Sci U S A (2001) 2.19
Mutations in the Caenorhabditis elegans Na,K-ATPase alpha-subunit gene, eat-6, disrupt excitable cell function. J Neurosci (1995) 2.19
Lysosomal membrane dynamics: structure and interorganellar movement of a major lysosomal membrane glycoprotein. J Cell Biol (1986) 2.18
Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J Neurosci (1993) 2.16
Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proc Natl Acad Sci U S A (1995) 2.12
Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies. Proc Natl Acad Sci U S A (1993) 2.10
Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina. Proc Natl Acad Sci U S A (1991) 2.10
Chick myotendinous antigen. II. A novel extracellular glycoprotein complex consisting of large disulfide-linked subunits. J Cell Biol (1984) 2.10
Opioid peptide enkephalin: immunohistochemical mapping in rat central nervous system. Proc Natl Acad Sci U S A (1977) 2.07
Basal forebrain neurons in the dementia of Parkinson disease. Ann Neurol (1983) 2.06
Control of axonal caliber by neurofilament transport. J Cell Biol (1984) 2.03
Basal forebrain lesions in monkeys disrupt attention but not learning and memory. J Neurosci (1994) 2.00
Alzheimer amyloid protein precursor in the rat hippocampus: transport and processing through the perforant path. J Neurosci (1998) 2.00
Slow axonal transport of neurofilament proteins: impairment of beta,beta'-iminodipropionitrile administration. Science (1978) 2.00
Automated microscopy system for mosaic acquisition and processing. J Microsc (2006) 1.98
Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length. Neurobiol Dis (1998) 1.96
New perspectives on Alzheimer's disease. Annu Rev Neurosci (1986) 1.95
Protein topology of presenilin 1. Neuron (1996) 1.94
Acetylcholine sensitivity of muscle fiber membranes: mechanism of regulation by motoneurons. Science (1970) 1.92
Effects of PS1 deficiency on membrane protein trafficking in neurons. Neuron (1998) 1.90
Hyperaccumulation of FAD-linked presenilin 1 variants in vivo. Nat Med (1997) 1.86
Mu opioid receptor phosphorylation, desensitization, and ligand efficacy. J Biol Chem (1997) 1.86
Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice. Neurobiol Aging (1998) 1.81
Comparative evaluation of synaptophysin-based methods for quantification of synapses. J Neurocytol (1996) 1.80
Acetylcholinesterase of human erythrocytes and neuromuscular junctions: homologies revealed by monoclonal antibodies. Proc Natl Acad Sci U S A (1982) 1.79
Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding. Proc Natl Acad Sci U S A (1992) 1.79
Human cannabinoid receptor 1: 5' exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse. Mol Psychiatry (2004) 1.78
Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures. Proc Natl Acad Sci U S A (1993) 1.75
Role of the beta-amyloid protein in Alzheimer's disease. FASEB J (1995) 1.75
Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]. Nat Genet (1993) 1.74
Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump. J Biol Chem (1988) 1.74
cDNA cloning of an orphan opiate receptor gene family member and its splice variant. FEBS Lett (1994) 1.72
Electron microscopic autoradiographic studies of gliogenesis in rat optic nerve. I. Cell proliferation. J Comp Neurol (1976) 1.71
Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase. Proc Natl Acad Sci U S A (2000) 1.70
The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons. J Neurosci (1996) 1.70
Age-related spatial reference and working memory deficits assessed in the water maze. Neurobiol Aging (1995) 1.69
AMPA glutamate receptor subunits are differentially distributed in rat brain. Neuroscience (1993) 1.66
Calf and pea histone IV. 3. Complete amino acid sequence of pea seedling histone IV; comparison with the homologous calf thymus histone. J Biol Chem (1969) 1.66
Local-circuit neurones in the medial prefrontal cortex (areas 25, 32 and 24b) in the rat: morphology and quantitative distribution. J Comp Neurol (1997) 1.64
Electron microscopic autoradiographic studies of gliogenesis in rat optic nerve. II. Time of origin. J Comp Neurol (1976) 1.61
Aggregates of acetylcholine receptors are associated with plaques of a basal lamina heparan sulfate proteoglycan on the surface of skeletal muscle fibers. J Cell Biol (1983) 1.61
Cellular localization of a metabotropic glutamate receptor in rat brain. Neuron (1992) 1.60
Kinetics of biosynthesis of acetylcholine receptor and subsequent incorporation into plasma membrane of cultured chick skeletal muscle. Cell (1977) 1.59
Biochemical characterization and localization of a non-N-methyl-D-aspartate glutamate receptor in rat brain. J Neurochem (1992) 1.58
Newly synthesized acetylcholine receptors are located in the Golgi apparatus. J Cell Biol (1978) 1.57
Excitotoxic neuronal death in the immature brain is an apoptosis-necrosis morphological continuum. J Comp Neurol (1997) 1.57
Neurofibrillary tangles and senile plaques in aged bears. J Neuropathol Exp Neurol (1988) 1.56
Effect of intermittent high dose parenteral corticosteroids on the alveolitis of idiopathic pulmonary fibrosis. Am Rev Respir Dis (1983) 1.56
Changes in neurofilament transport coincide temporally with alterations in the caliber of axons in regenerating motor fibers. J Cell Biol (1985) 1.55
Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo. Neuron (1993) 1.54
Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system. J Neurosci (1993) 1.54
Molecular characterization and expression of the (Na+ + K+)-ATPase alpha-subunit in Drosophila melanogaster. EMBO J (1989) 1.54
Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models. J Neurosci (1995) 1.50
A modified histochemical technique to visualize acetylcholinesterase-containing axons. J Histochem Cytochem (1985) 1.49
The (Na+ + K+)-ATPase of chick sensory neurons. Studies on biosynthesis and intracellular transport. J Biol Chem (1986) 1.49
Phosphorylated neurofilament antigens in neurofibrillary tangles in Alzheimer's disease. J Neuropathol Exp Neurol (1986) 1.48
Baseline characteristics of the patient population in the Saxagliptin Assessment of Vascular Outcomes Recorded in patients with diabetes mellitus (SAVOR)-TIMI 53 trial. Diabetes Metab Res Rev (2013) 1.47