Published in Spine (Phila Pa 1976) on October 01, 1984
The sequence of the human genome. Science (2001) 101.55
ALSPAC--the Avon Longitudinal Study of Parents and Children. I. Study methodology. Paediatr Perinat Epidemiol (2001) 14.31
Implementing findings of research. BMJ (1994) 12.85
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Restriction endonucleases for pulsed field mapping of bacterial genomes. Nucleic Acids Res (1987) 7.03
It's not 'just deprivation': why do equally deprived UK cities experience different health outcomes? Public Health (2010) 6.65
Current concepts in the management of Helicobacter pylori infection--the Maastricht 2-2000 Consensus Report. Aliment Pharmacol Ther (2002) 6.17
Qualitative research methods in general practice and primary care. Fam Pract (1995) 5.72
Assessment of clinical competence. Lancet (2001) 5.21
Does continuing medical education in general practice make a difference? BMJ (1999) 4.40
Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology. J Neurosci (1999) 4.27
Gene coding assignments for growth restriction, neutralization and subgroup specificities of the W and DS-1 strains of human rotavirus. J Gen Virol (1983) 4.25
Comprehensive discharge planning for the hospitalized elderly. A randomized clinical trial. Ann Intern Med (1994) 4.09
Smoking cessation with and without assistance: a population-based analysis. Am J Prev Med (2000) 3.92
New ages for the last Australian megafauna: continent-wide extinction about 46,000 years ago. Science (2001) 3.91
Guidelines on the irritable bowel syndrome: mechanisms and practical management. Gut (2007) 3.87
Consent and confidentiality in teaching in general practice: survey of patients' views on presence of students. BMJ (1997) 3.64
p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast. EMBO J (1991) 3.55
Factors affecting the decision to consult with dyspepsia: comparison of consulters and non-consulters. J R Coll Gen Pract (1989) 3.53
A study of general practitioners' reasons for changing their prescribing behaviour. BMJ (1996) 3.36
Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists. J Med Chem (2000) 3.34
Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. J Med Chem (2001) 3.24
Why do qualitative research? BMJ (1995) 3.23
Sequence of the fourth gene of human rotaviruses recovered from asymptomatic or symptomatic infections. J Virol (1988) 3.20
Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood. Proc Natl Acad Sci U S A (2000) 3.16
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CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion. Neurology (2012) 3.12
Lead-contaminated soil abatement and urban children's blood lead levels. JAMA (1993) 3.06
Rescue and serotypic characterization of noncultivable human rotavirus by gene reassortment. Infect Immun (1982) 2.97
Recognition of faux pas by normally developing children and children with Asperger syndrome or high-functioning autism. J Autism Dev Disord (1999) 2.90
Nanostructured high-strength molybdenum alloys with unprecedented tensile ductility. Nat Mater (2013) 2.90
Mental health care training priorities in general practice. Br J Gen Pract (1997) 2.79
Why do early-emerging tree seedlings have survival advantages?: a test using Acer rubrum (Aceraceae). Am J Bot (1997) 2.77
Inhaled nitric oxide. A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation (1991) 2.62
General practitioners with special clinical interests. Clin Med (2001) 2.61
Evaluation of filter paper blood lead methods: results of a pilot proficiency testing program. Clin Chem (1999) 2.58
Molecular characterization and transcriptional analysis of type 8 capsule genes in Staphylococcus aureus. J Bacteriol (1997) 2.58
Clinical manifestations and diagnosis of acute pyrethroid poisoning. Arch Toxicol (1989) 2.50
Prescribing at the interface between hospitals and general practitioners. BMJ (1992) 2.47
The skeletal muscle calcium release channel: coupled O2 sensor and NO signaling functions. Cell (2000) 2.41
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1. EMBO J (2001) 2.32
Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: a 24-week, randomized, placebo-controlled trial. Diabetes Obes Metab (2013) 2.31
The early detection of colorectal cancer in primary care. Br J Gen Pract (1999) 2.26
Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection. Immunity (1996) 2.24
Initial validation of a diagnostic questionnaire for gastroesophageal reflux disease. Am J Gastroenterol (2001) 2.23
Time trend analysis and variations in prescribing lipid lowering drugs in general practice. BMJ (1998) 2.21
Selection of the T cell repertoire. Annu Rev Immunol (1999) 2.21
Open access endoscopy. Br Med J (Clin Res Ed) (1985) 2.18
Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington disease. Am J Med Genet A (2003) 2.15
Psychotherapy and bulimia nervosa. Longer-term effects of interpersonal psychotherapy, behavior therapy, and cognitive behavior therapy. Arch Gen Psychiatry (1993) 2.12
Modification and validation of the Birmingham Vasculitis Activity Score (version 3). Ann Rheum Dis (2008) 2.12
Rectal bleeding: prevalence and consultation behaviour. BMJ (1995) 2.11
Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: a phase I/II clinical trial. Bone Marrow Transplant (2008) 2.10
Existent T-cell and antibody immunity to HER-2/neu protein in patients with breast cancer. Cancer Res (1994) 2.10
Improving the detection rate of early gastric cancer requires more than open access gastroscopy: a five year study. Gut (1997) 2.09
Predictors of smoking cessation in U.S. adolescents. Am J Prev Med (1999) 2.09
Assessment of the performance of five intensive care scoring models within a large Scottish database. Crit Care Med (2000) 2.08
The impact of new technology on general practice. J R Coll Gen Pract (1986) 2.08
Hypercholesterolaemia: not all cases warrant treatment. BMJ (1993) 2.06
IMPACT trial results should not change current standard of care of 100 days for cytomegalovirus prophylaxis. Am J Transplant (2010) 2.05
Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation. EMBO J (1997) 2.02
Patients' attitudes to chaperones. J R Coll Gen Pract (1985) 2.01
Experimental atherosclerosis in rhesus monkeys. II. Cellular elements of proliferative lesions and possible role of cytoplasmic degeneration in pathogenesis as studied by electron microscopy. Exp Mol Pathol (1967) 2.00
Massive Surgical Emphysema, Pneumothorax, Pneumoperitoneum. Br Med J (1945) 2.00
Further characterization of endometrial integrins during the menstrual cycle and in pregnancy. Fertil Steril (1994) 1.99
Variability in 28-day outcomes for very low birth weight infants: an analysis of 11 neonatal intensive care units. Pediatrics (1988) 1.99
Smoking, air pollution, and the high rates of lung cancer in Shenyang, China. J Natl Cancer Inst (1989) 1.99
Second gene (nifH*) coding for a nitrogenase iron protein in Azotobacter chroococcum is adjacent to a gene coding for a ferredoxin-like protein. EMBO J (1986) 1.96
Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects. Proc Natl Acad Sci U S A (1999) 1.95
Indoor radon and lung cancer in China. J Natl Cancer Inst (1990) 1.95
A dumbbell-shaped, double-hairpin structure of DNA: a thermodynamic investigation. Biochemistry (1987) 1.92
Pseudomonas aeruginosa ExoS and ExoT. Rev Physiol Biochem Pharmacol (2004) 1.91
Cultivation and characterization of three strains of murine rotavirus. J Virol (1986) 1.90
Reverse transcriptase in a clinical strain of Escherichia coli: production of branched RNA-linked msDNA. Science (1989) 1.89
A phospholipid acts as a chaperone in assembly of a membrane transport protein. J Biol Chem (1996) 1.89
Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2. J Biol Chem (1996) 1.87
Effects of pyrethroid insecticides on subjects engaged in packaging pyrethroids. Br J Ind Med (1988) 1.87
Phosphoenolpyruvate carboxylase from the crassulacean plant Bryophyllum fedtschenkoi Hamet et Perrier. Purification, molecular and kinetic properties. Biochem J (1978) 1.86
The primary structure of rat ribosomal protein S12. The relationship of rat S12 to other ribosomal proteins and a correlation of the amino acid sequences of rat and yeast ribosomal proteins. J Biol Chem (1987) 1.86
Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study: What is in store for the oldest old? Neurology (1996) 1.85
Morphologic and mechanical characteristics of engineered bovine arteries. J Vasc Surg (2001) 1.84
II. Derangements of the Knee: Based Upon a Personal Experience of Over Five Hundred Operations. Ann Surg (1909) 1.79
Genome size and complexity in Azotobacter chroococcum. J Gen Microbiol (1984) 1.79
The development of the PAR Index (Peer Assessment Rating): reliability and validity. Eur J Orthod (1992) 1.78
Incidence and causes of rectal bleeding in general practice as detected by colonoscopy. Br J Gen Pract (1996) 1.78
Local anesthesia for functional endoscopic sinus surgery employing small volumes of epinephrine-containing solutions of lidocaine produces profound hypotension. Acta Anaesthesiol Scand (2005) 1.77
General practitioners' views on over the counter sales by community pharmacists. BMJ (1996) 1.76
Mental health and psychological well-being among the old and the very old living at home. Br J Psychiatry (1987) 1.75
Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes. J Biol Chem (1995) 1.75
Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014. J Intern Med (2014) 1.75
Reasons for consultation in irritable bowel syndrome: symptoms and patient characteristics. Br J Gen Pract (1992) 1.75
Standardized or real patients to test clinical competence? The long case revisited. Med Educ (2001) 1.74
The need for chaperones. BMJ (1993) 1.72
Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules. Proc Natl Acad Sci U S A (1998) 1.71
Effects of local anesthetics on single channel behavior of skeletal muscle calcium release channel. J Gen Physiol (1993) 1.69
Small fenestra stapedotomies with and without KTP laser: a comparison. Laryngoscope (1989) 1.68
ACAPs are arf6 GTPase-activating proteins that function in the cell periphery. J Cell Biol (2000) 1.66
Goblet cell glycoprotein and tracheal gland hypertrophy in rat airways: the effect of tobacco smoke with or without the anti-inflammatory agent phenylmethyloxadiazole. Br J Exp Pathol (1973) 1.66
High-dose/activation-associated tolerance: a mechanism for allograft tolerance. Transplantation (1997) 1.65