Published in Mol Cell Biol on November 01, 1984
Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression. Nucleic Acids Res (1994) 10.72
A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae. Microbiol Rev (1987) 7.00
Yeast regulatory gene GAL3: carbon regulation; UASGal elements in common with GAL1, GAL2, GAL7, GAL10, GAL80, and MEL1; encoded protein strikingly similar to yeast and Escherichia coli galactokinases. Mol Cell Biol (1988) 4.82
Correlation of two-hybrid affinity data with in vitro measurements. Mol Cell Biol (1995) 4.63
Repression by SSN6-TUP1 is directed by MIG1, a repressor/activator protein. Proc Natl Acad Sci U S A (1995) 4.06
A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae. Mol Cell Biol (1985) 3.98
A general upstream binding factor for genes of the yeast translational apparatus. EMBO J (1985) 3.72
Molecular analysis of SSN6, a gene functionally related to the SNF1 protein kinase of Saccharomyces cerevisiae. Mol Cell Biol (1987) 3.57
Functional interdependence of the yeast SNF2, SNF5, and SNF6 proteins in transcriptional activation. Proc Natl Acad Sci U S A (1991) 3.55
A GAL family of upstream activating sequences in yeast: roles in both induction and repression of transcription. EMBO J (1986) 3.29
The Mus81/Mms4 endonuclease acts independently of double-Holliday junction resolution to promote a distinct subset of crossovers during meiosis in budding yeast. Genetics (2003) 3.22
Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators. Proc Natl Acad Sci U S A (1994) 3.18
Fused protein domains inhibit DNA binding by LexA. Mol Cell Biol (1992) 3.01
Two homologous zinc finger genes identified by multicopy suppression in a SNF1 protein kinase mutant of Saccharomyces cerevisiae. Mol Cell Biol (1993) 3.00
Tripartite upstream promoter element essential for expression of Saccharomyces cerevisiae ribosomal protein genes. Mol Cell Biol (1986) 3.00
The SNF5 protein of Saccharomyces cerevisiae is a glutamine- and proline-rich transcriptional activator that affects expression of a broad spectrum of genes. Mol Cell Biol (1990) 2.87
An RNA polymerase I enhancer in Saccharomyces cerevisiae. Mol Cell Biol (1986) 2.85
An essential Saccharomyces cerevisiae gene homologous to SNF2 encodes a helicase-related protein in a new family. Mol Cell Biol (1992) 2.78
IRF-7, a new interferon regulatory factor associated with Epstein-Barr virus latency. Mol Cell Biol (1997) 2.70
Transcriptional rewiring of fungal galactose-metabolism circuitry. Curr Biol (2007) 2.66
Two systems of glucose repression of the GAL1 promoter in Saccharomyces cerevisiae. Mol Cell Biol (1990) 2.65
Efficient expression of the Saccharomyces cerevisiae PGK gene depends on an upstream activation sequence but does not require TATA sequences. Mol Cell Biol (1986) 2.63
MET4, a leucine zipper protein, and centromere-binding factor 1 are both required for transcriptional activation of sulfur metabolism in Saccharomyces cerevisiae. Mol Cell Biol (1992) 2.51
Identification of proteins involved in the regulation of yeast iso- 1-cytochrome C expression by oxygen. EMBO J (1985) 2.50
A germline transformation analysis reveals flexibility in the organization of heat shock consensus elements. Nucleic Acids Res (1987) 2.48
Identification of sequences responsible for transcriptional activation of the allantoate permease gene in Saccharomyces cerevisiae. Mol Cell Biol (1989) 2.45
Histone H3 N-terminal mutations allow hyperactivation of the yeast GAL1 gene in vivo. EMBO J (1992) 2.42
GAL11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae. Mol Cell Biol (1988) 2.41
Involvement of the SIN4 global transcriptional regulator in the chromatin structure of Saccharomyces cerevisiae. Mol Cell Biol (1992) 2.39
In vivo DNA-binding properties of a yeast transcription activator protein. Mol Cell Biol (1987) 2.37
Differential DNA sequence recognition is a determinant of specificity in homeotic gene action. EMBO J (1992) 2.32
REB1, a yeast DNA-binding protein with many targets, is essential for growth and bears some resemblance to the oncogene myb. Mol Cell Biol (1990) 2.30
Null mutations in the SNF3 gene of Saccharomyces cerevisiae cause a different phenotype than do previously isolated missense mutations. Mol Cell Biol (1986) 2.30
Characterization of three related glucose repressors and genes they regulate in Saccharomyces cerevisiae. Genetics (1998) 2.27
Interaction of GAL4 and GAL80 gene regulatory proteins in vitro. Mol Cell Biol (1987) 2.26
Two acyl-coenzyme A oxidases in peroxisomes of the yeast Candida tropicalis: primary structures deduced from genomic DNA sequence. Proc Natl Acad Sci U S A (1986) 2.24
A new class of histone H2A mutations in Saccharomyces cerevisiae causes specific transcriptional defects in vivo. Mol Cell Biol (1995) 2.20
Regulation of sugar utilization in Saccharomyces species. J Bacteriol (1987) 2.16
Oncogenic transformation by vrel requires an amino-terminal activation domain. Mol Cell Biol (1990) 2.15
Characterization of a transcription factor involved in mother cell specific transcription of the yeast HO gene. EMBO J (1988) 2.15
Cloning of human and bovine homologs of SNF2/SWI2: a global activator of transcription in yeast S. cerevisiae. Nucleic Acids Res (1992) 2.14
The yeast PHO5 promoter: phosphate-control elements and sequences mediating mRNA start-site selection. Proc Natl Acad Sci U S A (1987) 2.12
Mutations that define the optimal half-site for binding yeast GCN4 activator protein and identify an ATF/CREB-like repressor that recognizes similar DNA sites. Mol Cell Biol (1990) 2.00
Multiple layers of regulation of human heat shock transcription factor 1. Mol Cell Biol (1995) 2.00
Efficient translational frameshifting occurs within a conserved sequence of the overlap between the two genes of a yeast Ty1 transposon. Proc Natl Acad Sci U S A (1988) 1.98
Cooperative DNA-binding by Bicoid provides a mechanism for threshold-dependent gene activation in the Drosophila embryo. EMBO J (1998) 1.97
Two zinc-finger-containing repressors are responsible for glucose repression of SUC2 expression. Mol Cell Biol (1996) 1.92
Meiotic induction of the yeast HOP1 gene is controlled by positive and negative regulatory sites. Mol Cell Biol (1992) 1.92
The organization and transcription of the galactose gene cluster of Kluyveromyces lactis. Nucleic Acids Res (1988) 1.91
Requirement of upstream activation sequences for nitrogen catabolite repression of the allantoin system genes in Saccharomyces cerevisiae. Mol Cell Biol (1989) 1.85
SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase II. Mol Cell Biol (1996) 1.81
Patterns of mitochondrial sorting in yeast zygotes. Mol Biol Cell (1993) 1.81
Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein. Mol Cell Biol (1993) 1.75
Elements involved in oxygen regulation of the Saccharomyces cerevisiae CYC7 gene. Mol Cell Biol (1987) 1.75
Continuous and widespread roles for the Swi-Snf complex in transcription. EMBO J (1999) 1.75
Sfh1p, a component of a novel chromatin-remodeling complex, is required for cell cycle progression. Mol Cell Biol (1997) 1.73
Identification of a regulatory region that mediates glucose-dependent induction of the Saccharomyces cerevisiae enolase gene ENO2. Mol Cell Biol (1986) 1.69
A regulatory shortcut between the Snf1 protein kinase and RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A (2000) 1.69
Gene limiting cadmium accumulation in rice. Proc Natl Acad Sci U S A (2010) 1.68
Duplicate upstream activating sequences in the promoter region of the Saccharomyces cerevisiae GAL7 gene. Mol Cell Biol (1986) 1.66
Analysis of URSG-mediated glucose repression of the GAL1 promoter of Saccharomyces cerevisiae. Genetics (1992) 1.64
Functional domains of the yeast regulatory protein GAL4. Proc Natl Acad Sci U S A (1986) 1.64
Identification of an upstream activating sequence and an upstream repressible sequence of the pyruvate kinase gene of the yeast Saccharomyces cerevisiae. Mol Cell Biol (1989) 1.59
Sth1p, a Saccharomyces cerevisiae Snf2p/Swi2p homolog, is an essential ATPase in RSC and differs from Snf/Swi in its interactions with histones and chromatin-associated proteins. Genetics (1998) 1.58
ADR1-mediated regulation of ADH2 requires an inverted repeat sequence. Mol Cell Biol (1986) 1.57
A hypoxic consensus operator and a constitutive activation region regulate the ANB1 gene of Saccharomyces cerevisiae. Mol Cell Biol (1990) 1.57
Increased dosage of the MSN1 gene restores invertase expression in yeast mutants defective in the SNF1 protein kinase. Nucleic Acids Res (1990) 1.55
DNA sequence preferences of GAL4 and PPR1: how a subset of Zn2 Cys6 binuclear cluster proteins recognizes DNA. Mol Cell Biol (1996) 1.54
Opposing regulatory functions of positive and negative elements in UASG control transcription of the yeast GAL genes. Mol Cell Biol (1990) 1.53
The relationship of regulatory proteins and DNase I hypersensitive sites in the yeast GAL1-10 genes. Nucleic Acids Res (1985) 1.50
Yeast SNF1 protein kinase interacts with SIP4, a C6 zinc cluster transcriptional activator: a new role for SNF1 in the glucose response. Mol Cell Biol (1996) 1.50
Isolation and DNA-binding characteristics of a protein involved in transcription activation of two divergently transcribed, essential yeast genes. EMBO J (1989) 1.50
Transcriptional activation by the acidic domain of Vmw65 requires the integrity of the domain and involves additional determinants distinct from those necessary for TFIIB binding. Mol Cell Biol (1993) 1.46
Upstream tRNA genes are essential for expression of small nuclear and cytoplasmic RNA genes in trypanosomes. Mol Cell Biol (1994) 1.44
Promoter specificity of the two transcriptional activation functions of the human oestrogen receptor in yeast. Nucleic Acids Res (1992) 1.40
Nucleosome loss activates CUP1 and HIS3 promoters to fully induced levels in the yeast Saccharomyces cerevisiae. Mol Cell Biol (1992) 1.39
Collisions between yeast chromosomal loci in vivo are governed by three layers of organization. Genes Dev (1999) 1.37
No strict alignment is required between a transcriptional activator binding site and the "TATA box" of a yeast gene. Proc Natl Acad Sci U S A (1988) 1.35
The intergenic region between the divergently transcribed niiA and niaD genes of Aspergillus nidulans contains multiple NirA binding sites which act bidirectionally. Mol Cell Biol (1995) 1.34
Multiple control elements in the TRP1 promoter of Saccharomyces cerevisiae. Mol Cell Biol (1986) 1.34
Assessment of aryl hydrocarbon receptor complex interactions using pBEVY plasmids: expressionvectors with bi-directional promoters for use in Saccharomyces cerevisiae. Nucleic Acids Res (1998) 1.34
A bipartite DNA-binding domain in yeast Reb1p. Mol Cell Biol (1993) 1.32
Adjacent upstream activation sequence elements synergistically regulate transcription of ADH2 in Saccharomyces cerevisiae. Mol Cell Biol (1989) 1.32
Human RNA polymerase II subunit hsRPB7 functions in yeast and influences stress survival and cell morphology. Mol Biol Cell (1995) 1.32
The protein factor which binds to the upstream activating sequence of Saccharomyces cerevisiae ENO1 gene. Nucleic Acids Res (1988) 1.31
Yeast Two-Hybrid: State of the Art. Biol Proced Online (1999) 1.31
Mutational analysis of the GAL4-encoded transcriptional activator protein of Saccharomyces cerevisiae. Genetics (1988) 1.29
Multiple mechanisms mediate glucose repression of the yeast GAL1 gene. Proc Natl Acad Sci U S A (1992) 1.29
Identification and purification of a Saccharomyces cerevisiae protein with the DNA binding specificity of mammalian activating transcription factor. Proc Natl Acad Sci U S A (1989) 1.28
The nucleotide sequence of the yeast MEL1 gene. Nucleic Acids Res (1985) 1.28
Activation of polyomavirus DNA replication by yeast GAL4 is dependent on its transcriptional activation domains. EMBO J (1991) 1.27
Phosphorylated forms of GAL4 are correlated with ability to activate transcription. Mol Cell Biol (1990) 1.26
Mutations that increase the activity of a transcriptional activator in yeast and mammalian cells. Proc Natl Acad Sci U S A (1990) 1.24
Point mutations implicate repeated sequences as essential elements of the CYC7 negative upstream site in Saccharomyces cerevisiae. Mol Cell Biol (1985) 1.23
Multiple GAL pathway gene clusters evolved independently and by different mechanisms in fungi. Proc Natl Acad Sci U S A (2010) 1.23
Positive regulation of the beta-galactosidase gene from Kluyveromyces lactis is mediated by an upstream activation site that shows homology to the GAL upstream activation site of Saccharomyces cerevisiae. Mol Cell Biol (1987) 1.23
Structure of the transcriptionally repressed phosphate-repressible acid phosphatase gene (PHO5) of Saccharomyces cerevisiae. Mol Cell Biol (1986) 1.22
Dissection of the ADR1 protein reveals multiple, functionally redundant activation domains interspersed with inhibitory regions: evidence for a repressor binding to the ADR1c region. Mol Cell Biol (1994) 1.21
Functional characterization of the Arabidopsis eukaryotic translation initiation factor 5A-2 that plays a crucial role in plant growth and development by regulating cell division, cell growth, and cell death. Plant Physiol (2007) 1.19
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
Nature of Col E 1 plasmid replication in Escherichia coli in the presence of the chloramphenicol. J Bacteriol (1972) 46.61
Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis. Gene (1983) 44.52
Analysis of restriction fragments of T7 DNA and determination of molecular weights by electrophoresis in neutral and alkaline gels. J Mol Biol (1977) 33.84
Mapping of RNA by a modification of the Berk-Sharp procedure: the 5' termini of 15 S beta-globin mRNA precursor and mature 10 s beta-globin mRNA have identical map coordinates. Nucleic Acids Res (1979) 31.23
Prolonged incubation in calcium chloride improves the competence of Escherichia coli cells. Gene (1979) 25.53
Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol Cell Biol (1984) 20.61
Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol (1983) 12.99
Construction and characterization of new cloning vehicles. I. Ampicillin-resistant derivatives of the plasmid pMB9. Gene (1977) 12.93
A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site. Proc Natl Acad Sci U S A (1982) 11.42
Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1981) 9.45
Protein expression in E. coli minicells by recombinant plasmids. Cell (1977) 8.74
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Regulation of genes controlling synthesis of the galactose pathway enzymes in yeast. Genetics (1966) 7.56
The organization and transcription of the galactose gene cluster of Saccharomyces. J Mol Biol (1981) 7.44
DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo. Cell (1983) 7.39
Transformation and preservation of competent bacterial cells by freezing. Methods Enzymol (1979) 7.33
Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol Cell Biol (1984) 6.23
Isolation of the yeast regulatory gene GAL4 and analysis of its dosage effects on the galactose/melibiose regulon. Proc Natl Acad Sci U S A (1982) 6.22
Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region. Cell (1983) 6.01
Induction of galactokinase in Saccharomyces cerevisiae: kinetics of induction and glucose effects. J Bacteriol (1972) 5.57
Primary structure of the Saccharomyces cerevisiae GAL4 gene. Mol Cell Biol (1984) 5.49
Isolation and preliminary characterization of the GAL4 gene, a positive regulator of transcription in yeast. Proc Natl Acad Sci U S A (1982) 4.93
The rapid purification of T4 DNA ligase from a lambda T4 lig lysogen. J Biol Chem (1980) 4.82
Yeast genes fused to beta-galactosidase in Escherichia coli can be expressed normally in yeast. Proc Natl Acad Sci U S A (1981) 4.79
Constitutive synthesis of the GAL4 protein, a galactose pathway regulator in Saccharomyces cerevisiae. Cell (1979) 4.61
Function of positive regulatory gene gal4 in the synthesis of galactose pathway enzymes in Saccharomyces cerevisiae: evidence that the GAL81 region codes for part of the gal4 protein. J Bacteriol (1980) 4.36
Genetic control of galactokinase synthesis in Saccharomyces cerevisiae: evidence for constitutive expression of the positive regulatory gene gal4. J Bacteriol (1978) 4.18
Uninducible mutants in the gal i locus of Saccharomyces cerevisiae. J Bacteriol (1972) 3.91
Recessive mutations conferring resistance to carbon catabolite repression of galactokinase synthesis in Saccharomyces cerevisiae. J Bacteriol (1983) 2.73
Regulation of expression of the galactose gene cluster in Saccharomyces cerevisiae. Isolation and characterization of the regulatory gene GAL4. Mol Gen Genet (1983) 2.66
Analysis of the transcriptional enhancer effect. Cold Spring Harb Symp Quant Biol (1983) 1.99
Construction and characterization of E. coli promoter-probe plasmid vectors. I. Cloning of promoter-containing DNA fragments. Gene (1979) 1.87
Nucleotide sequence of the transcriptional initiation region of the yeast GAL7 gene. Nucleic Acids Res (1983) 1.77
GAL4-VP16 is an unusually potent transcriptional activator. Nature (1988) 16.53
Deletion analysis of GAL4 defines two transcriptional activating segments. Cell (1987) 14.13
Construction of plasmids carrying the cI gene of bacteriophage lambda. Proc Natl Acad Sci U S A (1976) 13.10
A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site. Proc Natl Acad Sci U S A (1982) 11.42
Specific DNA binding of GAL4, a positive regulatory protein of yeast. Cell (1985) 10.25
Gene regulation by proteins acting nearby and at a distance. Nature (1986) 9.71
A new class of yeast transcriptional activators. Cell (1987) 9.53
Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1981) 9.45
Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli. Gene (1983) 8.85
A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor. Cell (1985) 8.30
A vector for expressing GAL4(1-147) fusions in mammalian cells. Nucleic Acids Res (1989) 8.06
Negative effect of the transcriptional activator GAL4. Nature (1988) 7.15
Autoregulation and function of a repressor in bacteriophage lambda. Science (1976) 6.83
Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein. Science (1986) 6.79
Structure of the lambda operators. Nature (1973) 6.66
How the lambda repressor and cro work. Cell (1980) 6.65
Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol Cell Biol (1984) 6.23
Sequence of a repressor-binding site in the DNA of bacteriophage lamda. Nature (1974) 6.22
Improved methods for maximizing expression of a cloned gene: a bacterium that synthesizes rabbit beta-globin. Cell (1980) 6.20
Mechanism of action of the lexA gene product. Proc Natl Acad Sci U S A (1981) 6.13
Cooperative binding of lambda repressors to sites separated by integral turns of the DNA helix. Cell (1986) 5.81
DNA recognition by GAL4: structure of a protein-DNA complex. Nature (1992) 5.60
Homology among DNA-binding proteins suggests use of a conserved super-secondary structure. Nature (1982) 5.21
Multiple repressor binding at the operators in bacteriophage lambda. Proc Natl Acad Sci U S A (1973) 5.15
Interactions between DNA-bound repressors govern regulation by the lambda phage repressor. Proc Natl Acad Sci U S A (1979) 5.02
Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization. Proc Natl Acad Sci U S A (1984) 4.90
The rapid purification of T4 DNA ligase from a lambda T4 lig lysogen. J Biol Chem (1980) 4.82
Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin. Proc Natl Acad Sci U S A (1980) 4.77
Novel properties of a restriction endonuclease isolated from Haemophilus parahaemolyticus. Proc Natl Acad Sci U S A (1976) 4.74
Recognition of a DNA operator by the repressor of phage 434: a view at high resolution. Science (1988) 4.60
A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives. Nature (1990) 4.57
lambda Repressor and cro--components of an efficient molecular switch. Nature (1981) 4.52
The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80. Cell (1987) 4.49
Mutants of GAL4 protein altered in an activation function. Cell (1987) 4.44
Mechanism of action of the cro protein of bacteriophage lambda. Proc Natl Acad Sci U S A (1978) 4.34
Recognition sequences of repressor and polymerase in the operators of bacteriophage lambda. Cell (1975) 4.28
Control elements in the DNA of bacteriophage lambda. Cold Spring Harb Symp Quant Biol (1974) 4.23
Specific binding of the lambda phage repressor to lambda DNA. Nature (1967) 4.23
A bacterial repressor protein or a yeast transcriptional terminator can block upstream activation of a yeast gene. Nature (1985) 4.08
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Transcription in yeast activated by a putative amphipathic alpha helix linked to a DNA binding unit. Nature (1988) 3.93
Maximizing gene expression on a plasmid using recombination in vitro. Cell (1978) 3.84
Repressor structure and the mechanism of positive control. Cell (1983) 3.82
GAL4 activates gene expression in mammalian cells. Cell (1988) 3.81
GAL4 activates transcription in Drosophila. Nature (1988) 3.73
Cooperative DNA binding of the yeast transcriptional activator GAL4. Proc Natl Acad Sci U S A (1988) 3.72
The lambda repressor contains two domains. Proc Natl Acad Sci U S A (1979) 3.68
A general method for maximizing the expression of a cloned gene. Proc Natl Acad Sci U S A (1979) 3.67
GAL4 derivatives function alone and synergistically with mammalian activators in vitro. Cell (1988) 3.67
An amino-terminal fragment of GAL4 binds DNA as a dimer. J Mol Biol (1989) 3.65
Gene regulation at the right operator (OR) bacteriophage lambda. I. OR3 and autogenous negative control by repressor. J Mol Biol (1980) 3.64
Generating yeast transcriptional activators containing no yeast protein sequences. Nature (1991) 3.21
Penicillin-sensitive enzymes and penicillin-binding components in bacterial cells. Ann N Y Acad Sci (1974) 3.16
Lambda repressor turns off transcription of its own gene. Proc Natl Acad Sci U S A (1975) 3.12
The lexA gene product represses its own promoter. Proc Natl Acad Sci U S A (1980) 3.03
Structure of the repressor-operator complex of bacteriophage 434. Nature (1987) 3.00
How different eukaryotic transcriptional activators can cooperate promiscuously. Nature (1990) 2.91
Contact with a component of the polymerase II holoenzyme suffices for gene activation. Cell (1995) 2.85
Regulatory functions of the lambda repressor reside in the amino-terminal domain. Nature (1979) 2.77
Determinants of binding-site specificity among yeast C6 zinc cluster proteins. Science (1993) 2.57
DNA loops induced by cooperative binding of lambda repressor. Nature (1986) 2.50
Effect of non-contacted bases on the affinity of 434 operator for 434 repressor and Cro. Nature (1987) 2.49
An activator target in the RNA polymerase II holoenzyme. Mol Cell (1998) 2.37
Quantitation of putative activator-target affinities predicts transcriptional activating potentials. EMBO J (1996) 2.34
GAL11P: a yeast mutation that potentiates the effect of weak GAL4-derived activators. Cell (1990) 2.26
Characterizing wild-type and mutant promoters of the tetracycline resistance gene in pBR313. Nucleic Acids Res (1979) 2.23
The operators controlled by the lambda phage repressor. Proc Natl Acad Sci U S A (1968) 2.21
An HMG-like protein that can switch a transcriptional activator to a repressor. Nature (1994) 2.18
Promoters are in the operators in phage lambda. Nature (1974) 2.16
A potent GAL4 derivative activates transcription at a distance in vitro. Science (1990) 2.15
Structure of the operator-binding domain of bacteriophage lambda repressor: implications for DNA recognition and gene regulation. Cold Spring Harb Symp Quant Biol (1983) 2.15
Chromatin components as part of a putative transcriptional repressing complex. Proc Natl Acad Sci U S A (1998) 2.14
A new-specificity mutant of 434 repressor that defines an amino acid-base pair contact. Nature (1987) 2.13
Yeast activators stimulate plant gene expression. Nature (1988) 2.13
DNA twisting and the affinity of bacteriophage 434 operator for bacteriophage 434 repressor. Proc Natl Acad Sci U S A (1988) 2.08
Changing the binding specificity of a repressor by redesigning an alpha-helix. Nature (1985) 2.08
Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro. Mol Cell Biol (1989) 2.06
A phage repressor-operator complex at 7 A resolution. Nature (1985) 2.00
Gene regulation at the right operator (OR) of bacteriophage lambda. III. lambda repressor directly activates gene transcription. J Mol Biol (1980) 1.99
Structure of a phage 434 Cro/DNA complex. Nature (1988) 1.98
Cleavage of the lambda and P22 repressors by recA protein. J Biol Chem (1982) 1.97
Construction of overproducers of the bacteriophage 434 repressor and cro proteins. J Mol Appl Genet (1981) 1.95
Gene activation by recruitment of the RNA polymerase II holoenzyme. Genes Dev (1996) 1.90
Construction and characterization of E. coli promoter-probe plasmid vectors. I. Cloning of promoter-containing DNA fragments. Gene (1979) 1.87
Expression of the human fibroblast interferon gene in Escherichia coli. Proc Natl Acad Sci U S A (1980) 1.84
TSF3, a global regulatory protein that silences transcription of yeast GAL genes, also mediates repression by alpha 2 repressor and is identical to SIN4. Mol Cell Biol (1993) 1.82
In vitro repression of RNA synthesis by purified lambda phage repressor. Nat New Biol (1971) 1.82
Mutants of the catabolite activator protein of Escherichia coli that are specifically deficient in the gene-activation function. Proc Natl Acad Sci U S A (1987) 1.81
Regulated expression of an extrachromosomal human beta-interferon gene in mouse cells. Proc Natl Acad Sci U S A (1982) 1.80
Synthesis of simian virus 40 t antigen in Escherichia coli. Proc Natl Acad Sci U S A (1979) 1.70
New eukaryotic transcriptional repressors. Nature (1993) 1.68
How lambda repressor and lambda Cro distinguish between OR1 and OR3. Cell (1986) 1.68
A single glutamic acid residue plays a key role in the transcriptional activation function of lambda repressor. Cell (1989) 1.67
Completed DNA sequences and organization of repressor-binding sites in the operators of phage lambda. J Mol Biol (1977) 1.66
Cloning, sequencing, and characterization of the Bacillus subtilis biotin biosynthetic operon. J Bacteriol (1996) 1.66
Molecular cloning of the GAL80 gene from Saccharomyces cerevisiae and characterization of a gal80 deletion. Gene (1984) 1.64
Regulation of damage-inducible genes in Escherichia coli. J Mol Biol (1982) 1.63