Published in Eur J Biochem on December 01, 1981
Possible pathways for lysosomal enzyme delivery. J Cell Biol (1985) 3.25
Cloning and sequence analysis of cDNA for human cathepsin D. Proc Natl Acad Sci U S A (1985) 3.10
Compartmentation of asparagine-linked oligosaccharide processing in the Golgi apparatus. J Cell Biol (1983) 2.65
Biosynthesis and transport of cathepsin D in cultured human fibroblasts. J Cell Biol (1983) 2.29
Ultrastructural localization of the mannose 6-phosphate receptor in rat liver. J Cell Biol (1984) 2.08
Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor. J Cell Biol (1993) 1.29
Inhibition by cyanate of the processing of lysosomal enzymes. Biochem J (1983) 1.25
Phosphorylation, glycosylation, and proteolytic activity of the 52-kD estrogen-induced protein secreted by MCF7 cells. J Cell Biol (1987) 1.13
Imiglucerase in the treatment of Gaucher disease: a history and perspective. Drug Des Devel Ther (2012) 1.10
Neutral endopeptidase-24.11 (enkephalinase). Biosynthesis and localization in human fibroblasts. Biochem J (1987) 1.06
Biosynthesis and transport of lysosomal enzymes in human monocytes and macrophages. Effects of ammonium chloride, zymosan and tunicamycin. Biochem J (1983) 1.03
Effect of monensin on intracellular transport and receptor-mediated endocytosis of lysosomal enzymes. Biochem J (1984) 1.02
Expression and maturation of human cathepsin D in baby-hamster kidney cells. Biochem J (1991) 1.01
Postendocytic maturation of acid hydrolases: evidence of prelysosomal processing. J Cell Biol (1987) 0.93
Purification and comparison of the structures of human liver acidic alpha-D-mannosidases A and B. Biochem J (1986) 0.93
Effects of ammonia on processing and secretion of precursor and mature lysosomal enzyme from macrophages of normal and pale ear mice: evidence for two distinct pathways. J Cell Biol (1985) 0.90
Two allelic forms of human arylsulfatase A with different numbers of asparagine-linked oligosaccharides. Am J Hum Genet (1983) 0.87
Molecular forms of beta-hexosaminidase and cathepsin D in serum and urine of healthy subjects and patients with elevated activity of lysosomal enzymes. Biochem J (1983) 0.87
Mucolipidosis III beta-N-acetyl-D-hexosaminidase A. Purification and properties. Biochem J (1982) 0.85
Myeloperoxidase is synthesized as larger phosphorylated precursor. EMBO J (1984) 0.84
Prolactin promotes the secretion of active cathepsin D at the basal side of rat mammary acini. Endocrinology (2008) 0.83
Conformation, structure and activation of bovine cathepsin D. Unfolding and refolding studies. Biochem J (1984) 0.78
Effect of carbohydrate position on lysosomal transport of procathepsin L. Mol Biol Cell (1998) 0.78
Structural analysis of the carbohydrate chains of beta-N-acetylhexosaminidases from bovine brain. Biochem J (1985) 0.75
Human biochemical genetics of enzyme proteins in the new age of molecular genetics. J Inherit Metab Dis (1986) 0.75
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein. Nature (1998) 7.43
Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight. J Biol Chem (1980) 6.60
Lysosomal enzymes and their receptors. Annu Rev Biochem (1986) 5.09
Mutant defective in processing of an enzyme located in the lysosome-like vacuole of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1981) 4.20
Intracellular receptor sorting during endocytosis: comparative immunoelectron microscopy of multiple receptors in rat liver. Cell (1984) 3.96
Biosynthesis of the vacuolar yeast glycoprotein carboxypeptidase Y. Conversion of precursor into the enzyme. Eur J Biochem (1978) 3.75
Biosynthesis of lysosomal enzymes in fibroblasts. Phosphorylation of mannose residues. J Biol Chem (1980) 3.48
Possible pathways for lysosomal enzyme delivery. J Cell Biol (1985) 3.25
Carbohydrate moiety of carboxypeptidase Y and perturbation of its biosynthesis. Eur J Biochem (1978) 2.55
Enzymatic phosphorylation of lysosomal enzymes in the presence of UDP-N-acetylglucosamine. Absence of the activity in I-cell fibroblasts. Biochem Biophys Res Commun (1981) 2.53
Evidence for lysosomal enzyme recognition by human fibroblasts via a phosphorylated carbohydrate moiety. Biochem J (1978) 2.46
Biosynthesis and transport of cathepsin D in cultured human fibroblasts. J Cell Biol (1983) 2.29
Antibody to mannose 6-phosphate specific receptor induces receptor deficiency in human fibroblasts. EMBO J (1984) 2.11
Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling. FASEB J (2000) 2.09
Ultrastructural localization of the mannose 6-phosphate receptor in rat liver. J Cell Biol (1984) 2.08
Synthesis of phosphorylated recognition marker in lysosomal enzymes is located in the cis part of Golgi apparatus. J Biol Chem (1982) 1.98
Mr 46,000 mannose 6-phosphate specific receptor: its role in targeting of lysosomal enzymes. EMBO J (1987) 1.81
Deficiency of UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase in organs of I-cell patients. Biochem Biophys Res Commun (1982) 1.78
UGA is translated as cysteine in pheromone 3 of Euplotes octocarinatus. Proc Natl Acad Sci U S A (1991) 1.77
Phosphorylated oligosaccharides in lysosomal enzymes: identification of alpha-N-acetylglucosamine(1)phospho(6)mannose diester groups. Proc Natl Acad Sci U S A (1980) 1.73
Juvenile and adult metachromatic leukodystrophy: partial restoration of arylsulfatase A (cerebroside sulfatase) activity by inhibitors of thiol proteinases. Proc Natl Acad Sci U S A (1983) 1.71
Subcellular location of two enzymes involved in the synthesis of phosphorylated recognition markers in lysosomal enzymes. J Biol Chem (1981) 1.68
Mutations in the arylsulfatase A pseudodeficiency allele causing metachromatic leukodystrophy. Am J Hum Genet (1991) 1.55
Is movement of mannose 6-phosphate-specific receptor triggered by binding of lysosomal enzymes? J Cell Biol (1987) 1.54
Participation of the tryptophan synthase inactivating system from yeast in the activation of chitin synthase. Biochem Biophys Res Commun (1973) 1.50
Carbohydrate-free carboxypeptidase Y is transferred into the lysosome-like yeast vacuole. Biochem Biophys Res Commun (1982) 1.49
Lysosomal enzyme precursors in human fibroblasts. Activation of cathepsin D precursor in vitro and activity of beta-hexosaminidase A precursor towards ganglioside GM2. Eur J Biochem (1982) 1.48
Internalization of blocking antibodies against mannose-6-phosphate specific receptors. EMBO J (1985) 1.48
Enhanced breakdown of arylsulfatase A in multiple sulfatase deficiency. Eur J Biochem (1982) 1.44
Synthesis and processing of arylsulfatase A in human skin fibroblasts. Hoppe Seylers Z Physiol Chem (1982) 1.44
Biosynthesis and maturation of arylsulfatase B in normal and mutant cultured human fibroblasts. J Biol Chem (1983) 1.40
UDP-N-acetylglucosamine:lysosomal enzyme precursor N-acetylglucosamine-1-phosphotransferase. Partial purification and characterization of the rat liver Golgi enzyme. J Biol Chem (1982) 1.37
Compartmentation of the tryptophan-synthase-proteolyzing system in Saccharomyces cerevisiae. Eur J Biochem (1974) 1.30
Mannose 6-phosphate-specific receptor is a transmembrane protein with a C-terminal extension oriented towards the cytosol. Biochem J (1985) 1.29
Processing of human cathepsin D in lysosomes in vitro. J Biol Chem (1985) 1.29
Processing of the phosphorylated recognition marker in lysosomal enzymes. Characterization and partial purification of a microsomal alpha-N-acetylglucosaminyl phosphodiesterase. J Biol Chem (1981) 1.26
Inhibition by cyanate of the processing of lysosomal enzymes. Biochem J (1983) 1.25
Biosynthesis of carboxypeptidase Y in yeast. Evidence for a precursor form of the glycoprotein. Biochem Biophys Res Commun (1976) 1.20
Cathepsin D and beta-hexosaminidase synthesized in the presence of 1-deoxynojirimycin accumulate in the endoplasmic reticulum. J Biol Chem (1984) 1.19
Synthesis and processing of alpha-galactosidase A in human fibroblasts. Evidence for different mutations in Fabry disease. J Biol Chem (1987) 1.19
Cathepsin D precursors in clathrin-coated organelles from human fibroblasts. J Cell Biol (1985) 1.16
Synthesis and transport of lysosomal acid phosphatase in normal and I-cell fibroblasts. J Biol Chem (1985) 1.16
46-kDa mannose 6-phosphate-specific receptor: biosynthesis, processing, subcellular location and topology. Biol Chem Hoppe Seyler (1987) 1.16
Biosynthesis of glycosylated human lysozyme mutants. J Biol Chem (1991) 1.15
Recognition of human urine alpha-N-acetylglucosaminidase by rat hepatocytes. Involvement of receptors specific for galactose, mannose 6-phosphate and mannose. Biochem J (1979) 1.15
Genetic heterogeneity of steroid sulfatase deficiency revealed with cDNA for human steroid sulfatase. Biochem Biophys Res Commun (1987) 1.14
Selective inactivity of TGF-beta/decorin complexes. FEBS Lett (1994) 1.10
Neutral endopeptidase-24.11 (enkephalinase). Biosynthesis and localization in human fibroblasts. Biochem J (1987) 1.06
Focal overexpression of insulin-like growth factor 2 by hepatocytes and cholangiocytes in viral liver cirrhosis. Br J Cancer (2003) 1.05
Pdcd4 inhibits growth of tumor cells by suppression of carbonic anhydrase type II. Mol Cell Endocrinol (2004) 1.05
Inactivation of chitin synthase in Saccharomyces cerevisiae. Arch Microbiol (1974) 1.04
Association of the precursor of cathepsin D with coated membranes. Kinetics and carbohydrate processing. Eur J Biochem (1987) 1.04
Application of magnetic chromatography to the isolation of lysosomes from fibroblasts of patients with lysosomal storage disorders. FEBS Lett (1998) 1.03
Biosynthesis and transport of lysosomal enzymes in human monocytes and macrophages. Effects of ammonium chloride, zymosan and tunicamycin. Biochem J (1983) 1.03
Effect of monensin on intracellular transport and receptor-mediated endocytosis of lysosomal enzymes. Biochem J (1984) 1.02
Expression and maturation of human cathepsin D in baby-hamster kidney cells. Biochem J (1991) 1.01
Transport and processing of lysosomal enzymes by smooth muscle cells and endothelial cells. Exp Cell Res (1981) 1.01
Tartrate-inhibitable acid phosphatase. Purification from placenta, characterization and subcellular distribution in fibroblasts. Hoppe Seylers Z Physiol Chem (1984) 1.01
Enhanced degradation of cathepsin D synthesized in the presence of the threonine analog beta-hydroxynorvaline. Arch Biochem Biophys (1984) 0.99
Cell surface-associated lysosomal enzymes in cultured human skin fibroblasts. Exp Cell Res (1979) 0.99
Synthesis and stability of arylsulfatase A and B in fibroblasts from multiple sulfatase deficiency. Eur J Biochem (1985) 0.98
Biosynthesis of acid alpha-glucosidase in late-onset forms of glycogenosis type II (Pompe's disease). FEBS Lett (1982) 0.98
On the effects of weak bases and monensin on sorting and processing of lysosomal enzymes in human cells. Eur J Cell Biol (1987) 0.98
Lysosomal enzyme precursors in coated vesicles derived from the exocytic and endocytic pathways. J Cell Biol (1987) 0.98
Inhibition of the apparent rate of synthesis on the vacuolar glycoprotein carboxypeptidase Y and its protein antigen by turicamycin in Saccharomyces cerevisiae. Antimicrob Agents Chemother (1976) 0.98
Synthesis and stability of steroid sulfatase in fibroblasts from multiple sulfatase deficiency. Biol Chem Hoppe Seyler (1988) 0.97
Phosphorylation of lysosomal enzymes in fibroblasts. Marked deficiency of N-acetylglucosamine-1-phosphotransferase in fibroblasts of patients with mucolipidosis III. Hoppe Seylers Z Physiol Chem (1982) 0.94
46-kDa mannose 6-phosphate-specific receptor: purification, subunit composition, chemical modification. Biol Chem Hoppe Seyler (1987) 0.92
Biosynthesis and maturation of alpha-N-acetylglucosaminidase in normal and Sanfilippo B-fibroblasts. Am J Hum Genet (1984) 0.91
Stress-induced apoptosis is impaired in cells with a lysosomal targeting defect but is not affected in cells synthesizing a catalytically inactive cathepsin D. Cell Death Differ (2003) 0.90
Differential segregation of human and hamster cathepsin D in transfected baby-hamster kidney cells. Biochem J (1991) 0.89
Immunoprecipitation of labeled antigens with Eupergit C1Z. Anal Biochem (1989) 0.89
Comparison of biosynthesis and subcellular distribution of lysozyme and lysosomal enzymes in U937 monocytes. Biochim Biophys Acta (1985) 0.88
Sanfilippo disease type B: presence of material cross reacting with antibodies against alpha-N-acetylglucosaminidase. Eur J Biochem (1976) 0.88
Two allelic forms of human arylsulfatase A with different numbers of asparagine-linked oligosaccharides. Am J Hum Genet (1983) 0.87
Effects of differentiation-inducing agents on synthesis, maturation and secretion of cathepsin D in U937 and HL-60 cells. Biol Chem Hoppe Seyler (1987) 0.87
Carbohydrate-deficient glycoprotein syndrome (CDGS)--glycosylation, folding and intracellular transport of newly synthesized glycoproteins. Eur J Cell Biol (1995) 0.87
Processing and transport of lysosomal enzymes in human monocyte line U937. Hoppe Seylers Z Physiol Chem (1984) 0.87
Molecular forms of beta-hexosaminidase and cathepsin D in serum and urine of healthy subjects and patients with elevated activity of lysosomal enzymes. Biochem J (1983) 0.87
Partial purification and characterization of heparan sulfate specific endoglucuronidase. Biochem Biophys Res Commun (1976) 0.87
A new biochemical subtype of the Sanfilippo syndrome: characterization of the storage material in cultured fibroblasts of Sanfilippo C patients. Eur J Biochem (1978) 0.86
Amplified crevicular leukocyte activity in aggressive periodontal disease. J Dent Res (2002) 0.86
Storage of mannose-containing material in cultured human mannosidosis cells and metabolic correction by pig kidney alpha-mannosidase. Hoppe Seylers Z Physiol Chem (1976) 0.86
Synthesis of lysosomal alpha-mannosidase in normal and mannosidosis fibroblasts. Biochem Biophys Res Commun (1983) 0.84
Myeloperoxidase is synthesized as larger phosphorylated precursor. EMBO J (1984) 0.84
Dephosphorylation of the mannose-6-phosphate recognition marker is localized in later compartments of the endocytic route. Identification of purple acid phosphatase (uteroferrin) as the candidate phosphatase. Eur J Biochem (1996) 0.84
Steroid sulfatase. Biosynthesis and processing in normal and mutant fibroblasts. Eur J Biochem (1986) 0.83
Distinctive inhibition of the lysosomal targeting of lysozyme and cathepsin D by drugs affecting pH gradients and protein kinase C. Biochem J (1994) 0.83
Sanfilippo's disease type A: sulfamidase activity in peripheral leukocytes of normal, heterozygous and homozygous individuals. Clin Chim Acta (1977) 0.82
Molecular organization of the human cathepsin D gene. DNA Cell Biol (1991) 0.82
Sequential detection of antigens in Western blots with differently colored products. Anal Biochem (1986) 0.82
Molecular forms of cathepsin D in coated vesicle preparations. Hoppe Seylers Z Physiol Chem (1983) 0.82
Human cathepsin D precursor is associated with a 60 kDa glycosylated polypeptide. Biochem Biophys Res Commun (1992) 0.82
Adhesion of human skin fibroblasts. Effect of tetravalent, divalent and monovalent concanavalin A. Exp Cell Res (1978) 0.82
Impaired phosphorylation of lysosomal enzymes in fibroblasts of patients with mucolipidosis III. Eur J Biochem (1982) 0.82
Natural killer cell-mediated cytotoxicity does not depend on recognition of mannose 6-phosphate residues. J Immunol (1985) 0.82
Endocytosis of lysosomal enzymes by non-parenchymal rat liver cells. Comparative study of lysosomal-enzyme uptake by hepatocytes and non-parenchymal liver cells. Biochem J (1979) 0.82