Published in Nature on February 24, 1983
Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay. Proc Natl Acad Sci U S A (1985) 6.94
Three trans-acting regulatory proteins of herpes simplex virus modulate immediate-early gene expression in a pathway involving positive and negative feedback regulation. J Virol (1985) 5.63
Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID. Mol Cell Biol (1988) 5.60
Stimulation of in vitro transcription from the SV40 early promoter by the enhancer involves a specific trans-acting factor. EMBO J (1984) 4.28
Use of a protein-blotting procedure and a specific DNA probe to identify nuclear proteins that recognize the promoter region of the transferrin receptor gene. Proc Natl Acad Sci U S A (1985) 3.91
Saturation mutagenesis of a yeast his3 "TATA element": genetic evidence for a specific TATA-binding protein. Proc Natl Acad Sci U S A (1988) 3.79
A general upstream binding factor for genes of the yeast translational apparatus. EMBO J (1985) 3.72
Factors involved in specific transcription by mammalian RNA polymerase II: role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex. Mol Cell Biol (1990) 3.72
Yeast and human TATA-binding proteins have nearly identical DNA sequence requirements for transcription in vitro. Mol Cell Biol (1990) 3.39
Constitutive and inducible Saccharomyces cerevisiae promoters: evidence for two distinct molecular mechanisms. Mol Cell Biol (1986) 3.37
Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection. Proc Natl Acad Sci U S A (1984) 3.24
Specific interaction of cellular factors with the B enhancer of polyoma virus. EMBO J (1985) 3.23
Yeast TATA-binding protein TFIID binds to TATA elements with both consensus and nonconsensus DNA sequences. Proc Natl Acad Sci U S A (1989) 3.18
Yeast TATA-box transcription factor gene. Proc Natl Acad Sci U S A (1989) 3.03
Direct interaction between adenovirus E1A protein and the TATA box binding transcription factor IID. Proc Natl Acad Sci U S A (1991) 2.95
Yeast mRNA initiation sites are determined primarily by specific sequences, not by the distance from the TATA element. EMBO J (1985) 2.87
Specific interaction between a transcription factor and the upstream element of the adenovirus-2 major late promoter. EMBO J (1985) 2.83
Identification of a factor in HeLa cells specific for an upstream transcriptional control sequence of an EIA-inducible adenovirus promoter and its relative abundance in infected and uninfected cells. Proc Natl Acad Sci U S A (1986) 2.81
Distinct TFIID complexes mediate the effect of different transcriptional activators. EMBO J (1993) 2.66
Functional regions of the cauliflower mosaic virus 35S RNA promoter determined by use of the firefly luciferase gene as a reporter of promoter activity. Proc Natl Acad Sci U S A (1987) 2.64
Duplicated CArG box domains have positive and mutually dependent regulatory roles in expression of the human alpha-cardiac actin gene. Mol Cell Biol (1987) 2.62
Linker scanning mutagenesis of the 5'-flanking region of the mouse beta-major-globin gene: sequence requirements for transcription in erythroid and nonerythroid cells. Mol Cell Biol (1985) 2.54
Mutational dissection of the 21 bp repeat region of the SV40 early promoter reveals that it contains overlapping elements of the early-early and late-early promoters. Nucleic Acids Res (1984) 2.52
Is actin a transcription initiation factor for RNA polymerase B? EMBO J (1984) 2.49
Stimulation of in vitro transcription from heterologous promoters by the simian virus 40 enhancer. Proc Natl Acad Sci U S A (1984) 2.44
Formation of stable preinitiation complexes is a prerequisite for ribosomal DNA transcription in vitro. Nucleic Acids Res (1983) 2.44
Stimulation of in vitro transcription by the upstream element of the adenovirus-2 major late promoter involves a specific factor. Nucleic Acids Res (1984) 2.31
Cloning of the gene encoding the yeast protein BTF1Y, which can substitute for the human TATA box-binding factor. Proc Natl Acad Sci U S A (1989) 2.30
Isolation of a class C transcription factor which forms a stable complex with tRNA genes. EMBO J (1984) 2.30
The small subunit of transcription factor IIF recruits RNA polymerase II into the preinitiation complex. Proc Natl Acad Sci U S A (1991) 2.29
Human cytomegalovirus immediate-early two protein region involved in negative regulation of the major immediate-early promoter. J Virol (1990) 2.28
A complex control region of the mouse rRNA gene directs accurate initiation by RNA polymerase I. Mol Cell Biol (1985) 2.24
RAP30/74: a general initiation factor that binds to RNA polymerase II. Mol Cell Biol (1988) 2.16
Factors and nucleotide sequences that direct ribosomal DNA transcription and their relationship to the stable transcription complex. Mol Cell Biol (1986) 2.04
The initiator directs the assembly of a transcription factor IID-dependent transcription complex. Proc Natl Acad Sci U S A (1991) 2.04
An upstream transcription factor, USF (MLTF), facilitates the formation of preinitiation complexes during in vitro chromatin assembly. EMBO J (1990) 1.99
TFIID is required for in vitro transcription of the human U6 gene by RNA polymerase III. EMBO J (1991) 1.97
Functional distinctions between yeast TATA elements. Mol Cell Biol (1989) 1.94
Purification of a factor specific for the upstream element of the adenovirus-2 major late promoter. EMBO J (1986) 1.94
The adenovirus major late promoter TATA box and initiation site are both necessary for transcription in vitro. Nucleic Acids Res (1984) 1.91
"Transactivation" control signals in the promoter of the herpesvirus thymidine kinase gene. Proc Natl Acad Sci U S A (1985) 1.87
The acidic transcriptional activator GAL-VP16 acts on preformed template-committed complexes. EMBO J (1992) 1.87
All six GC-motifs of the SV40 early upstream element contribute to promoter activity in vivo and in vitro. EMBO J (1985) 1.84
An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters. Proc Natl Acad Sci U S A (1989) 1.81
At least two nuclear proteins bind specifically to the Rous sarcoma virus long terminal repeat enhancer. Mol Cell Biol (1987) 1.74
Functional and biochemical interaction of the HTLV-I Tax1 transactivator with TBP. EMBO J (1993) 1.73
Stability of transcription complexes on class II genes. Mol Cell Biol (1989) 1.73
Differential activation of RNA polymerase III-transcribed genes by the polyomavirus enhancer and the adenovirus E1A gene products. Nucleic Acids Res (1985) 1.72
Purification of a yeast TATA box-binding protein that exhibits human transcription factor IID activity. Proc Natl Acad Sci U S A (1989) 1.70
RNA polymerase II ternary transcription complexes generated in vitro. Nucleic Acids Res (1983) 1.67
A stable transcription complex directs mouse ribosomal RNA synthesis by RNA polymerase I. Nucleic Acids Res (1983) 1.63
Mechanism of promoter selection by RNA polymerase II: mammalian transcription factors alpha and beta gamma promote entry of polymerase into the preinitiation complex. Proc Natl Acad Sci U S A (1991) 1.62
Monoclonal antibodies to NF-Y define its function in MHC class II and albumin gene transcription. EMBO J (1992) 1.62
ATA box transcription mutation in beta-thalassemia. Nucleic Acids Res (1983) 1.59
Factor substitution in a human HSP70 gene promoter: TATA-dependent and TATA-independent interactions. Mol Cell Biol (1990) 1.58
Factors involved in specific transcription by mammalian RNA polymerase II: purification and analysis of transcription factor IIA and identification of transcription factor IIJ. Mol Cell Biol (1992) 1.57
Upstream basal promoter element important for exclusive RNA polymerase III transcription of the EBER 2 gene. Mol Cell Biol (1993) 1.54
Ribosomal RNA transcription: proteins and DNA sequences involved in preinitiation complex formation. Proc Natl Acad Sci U S A (1985) 1.54
Factors responsible for the higher transcriptional activity of extracts of adenovirus-infected cells fractionate with the TATA box transcription factor. Mol Cell Biol (1988) 1.53
Transcription of adenovirus 2 major late and peptide IX genes under conditions of in vitro nucleosome assembly. Mol Cell Biol (1987) 1.52
Nucleotides in the polyomavirus enhancer that control viral transcription and DNA replication. Mol Cell Biol (1987) 1.48
Upstream regulatory regions required to stabilize binding to the TATA sequence in an adenovirus early promoter. Nucleic Acids Res (1987) 1.43
Factors involved in specific transcription by mammalian RNA polymerase II: identification of general transcription factor TFIIG. Proc Natl Acad Sci U S A (1990) 1.43
Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP. EMBO J (1997) 1.41
Binding of multiple factors to the MMTV promoter in crude and fractionated nuclear extracts. Nucleic Acids Res (1988) 1.41
Isolation of an active transcription initiation complex from HeLa cell-free extract. Proc Natl Acad Sci U S A (1984) 1.40
Genetic analysis connects SLX5 and SLX8 to the SUMO pathway in Saccharomyces cerevisiae. Genetics (2005) 1.40
Regulation of polyomavirus transcription by large tumor antigen. Proc Natl Acad Sci U S A (1984) 1.38
Different TBP-associated factors are required for mediating the stimulation of transcription in vitro by the acidic transactivator GAL-VP16 and the two nonacidic activation functions of the estrogen receptor. Nucleic Acids Res (1993) 1.37
RNA polymerase II-associated proteins are required for a DNA conformation change in the transcription initiation complex. Proc Natl Acad Sci U S A (1991) 1.36
Proteins that bind to RNA polymerase II are required for accurate initiation of transcription at the adenovirus 2 major late promoter. EMBO J (1986) 1.36
Yeast upstream activator protein GCN4 can stimulate transcription when its binding site replaces the TATA element. EMBO J (1989) 1.35
No strict alignment is required between a transcriptional activator binding site and the "TATA box" of a yeast gene. Proc Natl Acad Sci U S A (1988) 1.35
Engrailed, a homeodomain protein, can repress in vitro transcription by competition with the TATA box-binding protein transcription factor IID. Proc Natl Acad Sci U S A (1990) 1.35
Factors involved in specific transcription by mammalian RNA polymerase II: purification and characterization of general transcription factor TFIIE. Proc Natl Acad Sci U S A (1990) 1.34
Two distinct domains in the yeast transcription factor IID and evidence for a TATA box-induced conformational change. Mol Cell Biol (1991) 1.34
Specific cellular proteins bind to critical promoter sequences of the adenovirus early EIIa promoter. Nucleic Acids Res (1987) 1.33
Three tightly linked genes encoding human type I keratins: conservation of sequence in the 5'-untranslated leader and 5'-upstream regions of coexpressed keratin genes. Mol Cell Biol (1986) 1.33
Initiation of transcription of the erythroid promoter of the porphobilinogen deaminase gene is regulated by a cis-acting sequence around the cap site. Nucleic Acids Res (1990) 1.32
The bidirectional upstream element of the adenovirus-2 major late promoter binds a single monomeric molecule of the upstream factor. EMBO J (1987) 1.30
Yeast TATA binding protein interaction with DNA: fluorescence determination of oligomeric state, equilibrium binding, on-rate, and dissociation kinetics. Biochemistry (1995) 1.28
Footprinting of ribosomal RNA genes by transcription initiation factor and RNA polymerase I. Proc Natl Acad Sci U S A (1985) 1.28
Evidence for a factor required for transcriptional stimulation by the chimeric acidic activator GAL-VP16 in HeLa cell extracts. Proc Natl Acad Sci U S A (1991) 1.26
Transcription initiated by RNA polymerase II and purified transcription factors from liver. Cooperative action of transcription factors tau and epsilon in initial complex formation. J Biol Chem (1990) 1.26
Identification of a yeast protein homologous in function to the mammalian general transcription factor, TFIIA. EMBO J (1989) 1.25
The conserved carboxy-terminal domain of Saccharomyces cerevisiae TFIID is sufficient to support normal cell growth. Mol Cell Biol (1991) 1.25
Heat shock-regulated transcription in vitro from a reconstituted chromatin template. Proc Natl Acad Sci U S A (1991) 1.24
An RNA polymerase II transcription factor inactivated in poliovirus-infected cells copurifies with transcription factor TFIID. Mol Cell Biol (1988) 1.24
cDNA clone encoding Drosophila transcription factor TFIID. Proc Natl Acad Sci U S A (1990) 1.24
Adenovirus early region 1A protein increases the number of template molecules transcribed in cell-free extracts. Proc Natl Acad Sci U S A (1986) 1.23
Nuclear factors in human brain cells bind specifically to the JCV regulatory region. EMBO J (1988) 1.23
Cell-specificity of the chicken ovalbumin and conalbumin promoters. EMBO J (1987) 1.22
The general transcription factor RAP30 binds to RNA polymerase II and prevents it from binding nonspecifically to DNA. Mol Cell Biol (1992) 1.22
A downstream-element-binding factor facilitates assembly of a functional preinitiation complex at the simian virus 40 major late promoter. Mol Cell Biol (1990) 1.21
Contact points between transcription machinery and the fibroin gene promoter deduced by functional tests of single-base substitution mutants. Proc Natl Acad Sci U S A (1984) 1.21
Effects of high mobility group proteins 1 and 2 on initiation and elongation of specific transcription by RNA polymerase II in vitro. Nucleic Acids Res (1988) 1.20
Formation of the transcription initiation complex on mammalian rDNA. Mol Cell Biol (1986) 1.19
Modular structure of the beta-globin and the TK promoters. EMBO J (1984) 1.18
Core promoter of the mouse myelin basic protein gene governs brain-specific transcription in vitro. EMBO J (1990) 1.17
Heterogeneously initiated transcription from the pre-B- and B-cell-specific mb-1 promoter: analysis of the requirement for upstream factor-binding sites and initiation site sequences. Mol Cell Biol (1991) 1.17
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The ovalbumin gene-sequence of putative control regions. Nucleic Acids Res (1980) 18.04
A reliable method for the recovery of DNA fragments from agarose and acrylamide gels. Anal Biochem (1981) 15.38
The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants. Nucleic Acids Res (1981) 15.12
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Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature (1986) 11.35
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A human retinoic acid receptor which belongs to the family of nuclear receptors. Nature (1988) 9.07
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Multiple sequence motifs are involved in SV40 enhancer function. EMBO J (1986) 7.76
Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription. Nature (1985) 7.14
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Functional domains of the human estrogen receptor. Cell (1987) 6.52
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Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science (1995) 6.37
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A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes. Mol Cell (2000) 6.14
Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor. EMBO J (1986) 6.08
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The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements. Cell (1983) 5.67
Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science (1996) 5.55
Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor. Nature (1987) 5.47
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Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha. Nature (1995) 5.40
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Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line. Nucleic Acids Res (1982) 5.14
A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature (1991) 5.13
Identification of a second human retinoic acid receptor. Nature (1988) 5.11
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