Published in J Biol Chem on July 25, 1981
Regulation of actin microfilament integrity in living nonmuscle cells by the cAMP-dependent protein kinase and the myosin light chain kinase. J Cell Biol (1988) 2.72
In vivo phosphorylation of regulatory light chain of myosin II during mitosis of cultured cells. J Cell Biol (1994) 2.34
Endothelial cell cytosolic free calcium regulates neutrophil migration across monolayers of endothelial cells. J Cell Biol (1993) 2.23
Citron kinase, a Rho-dependent kinase, induces di-phosphorylation of regulatory light chain of myosin II. Mol Biol Cell (2003) 2.17
Isolation of the native form of chicken gizzard myosin light-chain kinase. Biochem J (1984) 1.93
Activation of calcineurin by limited proteolysis. Proc Natl Acad Sci U S A (1983) 1.85
Involvement of myosin light-chain kinase in endothelial cell retraction. Proc Natl Acad Sci U S A (1990) 1.82
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Light chain phosphorylation regulates the movement of smooth muscle myosin on actin filaments. J Cell Biol (1985) 1.63
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Structural changes accompanying phosphorylation of tarantula muscle myosin filaments. J Cell Biol (1987) 1.62
Molecular characterization of a mammalian smooth muscle myosin light chain kinase. J Biol Chem (1991) 1.59
Characterization of antibodies to smooth muscle myosin kinase and their use in localizing myosin kinase in nonmuscle cells. Proc Natl Acad Sci U S A (1981) 1.55
Regulation of contractile proteins by phosphorylation. J Clin Invest (1983) 1.40
Behavior of a fluorescent analogue of calmodulin in living 3T3 cells. J Cell Biol (1985) 1.39
In vitro actin filament sliding velocities produced by mixtures of different types of myosin. Biophys J (1997) 1.37
Effects of calcium and substrate on force-velocity relation and energy turnover in skinned smooth muscle of the guinea-pig. J Physiol (1985) 1.36
Myosin light chain kinase and myosin light chain phosphatase from Dictyostelium: effects of reversible phosphorylation on myosin structure and function. J Cell Biol (1987) 1.32
Infection of B lymphocytes by a human herpesvirus, Epstein-Barr virus, is blocked by calmodulin antagonists. Proc Natl Acad Sci U S A (1984) 1.31
Site-specific inhibition of myosin-mediated motility in vitro by monoclonal antibodies. J Cell Biol (1985) 1.31
Localization and activity of myosin light chain kinase isoforms during the cell cycle. J Cell Biol (2000) 1.29
Purification to homogeneity, characterization and monoclonal antibodies of phospholipid-sensitive Ca2+-dependent protein kinase from spleen. Biochem J (1983) 1.27
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Filamentous smooth muscle myosin is regulated by phosphorylation. J Cell Biol (1989) 1.21
Assembly of smooth muscle myosin minifilaments: effects of phosphorylation and nucleotide binding. J Cell Biol (1987) 1.16
Purification and characterization of inositol 1,4,5-trisphosphate 3-kinase from pig aortic smooth muscle. Biochem J (1988) 1.16
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Effect of metabolic inhibition on intracellular Ca2+, phosphorylation of myosin regulatory light chain and force in rat smooth muscle. J Physiol (1997) 1.15
Functional transitions in myosin: formation of a critical salt-bridge and transmission of effect to the sensitive tryptophan. Proc Natl Acad Sci U S A (1998) 1.14
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Identification by monoclonal antibodies and characterization of human platelet caldesmon. J Cell Biol (1986) 1.09
The temporal profile of calcium transients in voltage clamped gastric myocytes from Bufo marinus. J Physiol (1996) 1.09
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Preliminary characterization of a heat-stable protein from rat adipose tissue whose phosphorylation is stimulated by insulin. Biochem J (1982) 1.06
Biochemistry of smooth muscle myosin light chain kinase. Arch Biochem Biophys (2011) 1.06
Protein kinase C enhances myosin light-chain kinase effects on force development and ATPase activity in rat single skinned cardiac cells. Biochem J (1992) 1.03
Regulation of receptor capping in mouse lymphoma T cells by Ca2+-activated myosin light chain kinase. Proc Natl Acad Sci U S A (1984) 1.01
Inhibition of endothelial cell retraction by ATP depletion. Am J Pathol (1988) 0.98
Biochemical properties of chimeric skeletal and smooth muscle myosin light chain kinases. J Biol Chem (1992) 0.96
Activation of calcineurin and smooth muscle myosin light chain kinase by Met-to-Leu mutants of calmodulin. Biochem J (1998) 0.96
Excitation-contraction coupling and uncoupling in airway smooth muscle. Br J Clin Pharmacol (1985) 0.96
Rate-limiting energy-dependent steps controlling oxidative metabolism-contraction coupling in rabbit aorta. J Physiol (1992) 0.95
Functional chicken gizzard heavy meromyosin expression in and purification from baculovirus-infected insect cells. Proc Natl Acad Sci U S A (1995) 0.95
Spatial pattern of myosin phosphorylation in contracting smooth muscle cells: evidence for contractile zones. J Cell Biol (1988) 0.90
Regulation of contraction and thick filament assembly-disassembly in glycerinated vertebrate smooth muscle cells. J Cell Biol (1983) 0.89
Characterization of tightly associated smooth muscle myosin-myosin light-chain kinase-calmodulin complexes. J Mol Biol (2009) 0.88
The putative actin-binding role of hydrophobic residues Trp546 and Phe547 in chicken gizzard heavy meromyosin. Proc Natl Acad Sci U S A (1995) 0.87
Ca(2+)-calmodulin-dependent modification of smooth-muscle myosin light-chain kinase leading to its co-operative activation by calmodulin. Biochem J (1993) 0.84
Purification and characterization of myosin light-chain kinase from the rat pancreas. Biochem J (1989) 0.84
Analytical sedimentation studies of turkey gizzard myosin light chain kinase and telokin. Biophys J (1992) 0.84
Differential regulation of von Willebrand factor exocytosis and prostacyclin synthesis in electropermeabilized endothelial cell monolayers. Biochem J (1995) 0.84
Calcium dependence of the activation and inactivation kinetics of the light-activated phosphodiesterase of retinal rods. J Gen Physiol (1989) 0.84
Cytoskeletal reorganization of human platelets induced by the protein phosphatase 1/2 A inhibitors okadaic acid and calyculin A. Biochem J (1995) 0.82
On the tryptophan residue of smooth muscle myosin that responds to binding of nucleotide. Proc Natl Acad Sci U S A (2000) 0.82
Kinetic model for isometric contraction in smooth muscle on the basis of myosin phosphorylation hypothesis. Biophys J (1984) 0.82
The relationship between the action potential, intracellular calcium and force in intact phasic, guinea-pig uretic smooth muscle. J Physiol (1999) 0.82
Affinity labelling of smooth-muscle myosin light-chain kinase with 5'-[p-(fluorosulphonyl)benzoyl]adenosine. Biochem J (1993) 0.81
Purification, characterization and substrate specificity of calmodulin-dependent myosin light-chain kinase from bovine brain. Biochem J (1987) 0.81
Telokin (kinase-related protein) modulates the oligomeric state of smooth-muscle myosin light-chain kinase and its interaction with myosin filaments. Biochem J (1997) 0.81
Involvement of the C-terminal residues of the 20,000-dalton light chain of myosin on the regulation of smooth muscle actomyosin. Proc Natl Acad Sci U S A (1994) 0.80
Isolation of two myosin light-chain kinases from bovine carotid artery and their regulation by phosphorylation mediated by cyclic AMP-dependent protein kinase. Biochem J (1982) 0.79
Calcium-independent contraction in lysed cell models of teleost retinal cones: activation by unregulated myosin light chain kinase or high magnesium and loss of cAMP inhibition. J Cell Biol (1987) 0.79
Smooth muscle myosin light chain kinase, supramolecular organization, modulation of activity, and related conformational changes. Biophys J (1997) 0.78
Chicken smooth muscle myosin light chain kinase is acetylated on its NH2-terminal methionine. Mol Cell Biochem (1993) 0.78
Myosin light-chain kinase of smooth muscle stimulates myosin ATPase activity without phosphorylating myosin light chain. Proc Natl Acad Sci U S A (1999) 0.78
Study of the phosphorylatable light chains of skeletal and gizzard myosins by nuclear magnetic resonance spectroscopy. Biochem J (1988) 0.77
Kinase-related protein (telokin) is phosphorylated by smooth-muscle myosin light-chain kinase and modulates the kinase activity. Biochem J (1997) 0.77
Mechanisms of hypoxic vasodilatation of isolated rat mesenteric arteries: a comparison with metabolic inhibition. J Physiol (1999) 0.77
A quantitative model of myosin phosphorylation and the photomechanical response of the isolated sphincter pupillae of the frog iris. Biophys J (1987) 0.75
Minimum requirements for inhibition of smooth-muscle myosin light-chain kinase by synthetic peptides. Biochem J (1989) 0.75
Purification and characterization of protein kinase C from rabbit iris smooth muscle. Myosin light-chain phosphorylation in vitro and in intact muscle. Biochem J (1988) 0.75
Phosphorylation and partial sequence of pregnant sheep myometrium myosin light chain kinase. Mol Cell Biochem (1996) 0.75
Solution structure of a calmodulin-target peptide complex by multidimensional NMR. Science (1992) 6.16
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Identification of the NH2-terminal blocking group of calcineurin B as myristic acid. FEBS Lett (1982) 3.42
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Isolation and characterization of myosin from cloned mouse fibroblasts. Proc Natl Acad Sci U S A (1972) 3.24
Solution structure of Ca(2+)-calmodulin reveals flexible hand-like properties of its domains. Nat Struct Biol (2001) 3.18
Isolation and characterization of myosin and two myosin fragments from human blood platelets. Proc Natl Acad Sci U S A (1971) 3.09
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. Biochemistry (1992) 3.05
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proc Natl Acad Sci U S A (1992) 2.98
Complete amino-acid sequence of actin of rabbit skeletal muscle. Proc Natl Acad Sci U S A (1973) 2.96
Purification of cyclic 3',5'-nucleotide phosphodiesterase inhibitory protein by affinity chromatography on activator protein coupled to Sepharose. Biochemistry (1978) 2.89
Phosphorylation of platelet myosin increases actin-activated myosin ATPase activity. Nature (1975) 2.79
Discovery of a Ca2+- and calmodulin-dependent protein phosphatase: probable identity with calcineurin (CaM-BP80). FEBS Lett (1982) 2.75
Changes in D(--)-beta-hydroxybutyric dehydrogenase activity during brain maturation in the rat. J Biol Chem (1967) 2.55
Differential localization of myosin-II isozymes in human cultured cells and blood cells. J Cell Sci (1994) 2.36
Nonmuscle myosin II-B is required for normal development of the mouse heart. Proc Natl Acad Sci U S A (1997) 2.35
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Phosphorylation of smooth muscle myosin light chain kinase by the catalytic subunit of adenosine 3': 5'-monophosphate-dependent protein kinase. J Biol Chem (1978) 2.33
Myosin IIB is required for growth cone motility. J Neurosci (2001) 2.31
Conditional expression of a truncated fragment of nonmuscle myosin II-A alters cell shape but not cytokinesis in HeLa cells. Mol Biol Cell (2000) 2.20
Human platelet myosin light chain kinase requires the calcium-binding protein calmodulin for activity. Proc Natl Acad Sci U S A (1979) 2.14
The relationship between calmodulin binding and phosphorylation of smooth muscle myosin kinase by the catalytic subunit of 3':5' cAMP-dependent protein kinase. J Biol Chem (1981) 2.12
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Positive cooperative binding of calcium to bovine brain calmodulin. Biochemistry (1980) 2.08
Reversible phosphorylation of smooth muscle myosin, heavy meromyosin, and platelet myosin. J Biol Chem (1981) 2.06
Xenopus nonmuscle myosin heavy chain isoforms have different subcellular localizations and enzymatic activities. J Cell Biol (1996) 2.05
Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B. Biochemistry (1994) 2.02
Human nonmuscle myosin heavy chains are encoded by two genes located on different chromosomes. Circ Res (1991) 1.98
Effects of cations on affinity of calmodulin for calcium: ordered binding of calcium ions allows the specific activation of calmodulin-stimulated enzymes. Biochemistry (1981) 1.87
Functional domain structure of calcineurin A: mapping by limited proteolysis. Biochemistry (1989) 1.86
Phorbol ester-induced activation of human platelets is associated with protein kinase C phosphorylation of myosin light chains. Nature (1984) 1.86
Activation of calcineurin by limited proteolysis. Proc Natl Acad Sci U S A (1983) 1.85
Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase. J Biol Chem (1984) 1.71
Effect of phosphorylation of smooth muscle myosin on actin activation and Ca2+ regulation. Proc Natl Acad Sci U S A (1977) 1.70
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Cloning of the cDNA encoding human nonmuscle myosin heavy chain-B and analysis of human tissues with isoform-specific antibodies. J Muscle Res Cell Motil (1995) 1.66
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An insert of seven amino acids confers functional differences between smooth muscle myosins from the intestines and vasculature. J Biol Chem (1993) 1.58
Antigen-induced secretion of histamine and the phosphorylation of myosin by protein kinase C in rat basophilic leukemia cells. J Biol Chem (1989) 1.57
Characterization of antibodies to smooth muscle myosin kinase and their use in localizing myosin kinase in nonmuscle cells. Proc Natl Acad Sci U S A (1981) 1.55
Human heart and platelet actins are products of different genes. Science (1976) 1.55
Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. Science (1992) 1.53
Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain. Proc Natl Acad Sci U S A (1989) 1.52
Evidence for inserted sequences in the head region of nonmuscle myosin specific to the nervous system. Cloning of the cDNA encoding the myosin heavy chain-B isoform of vertebrate nonmuscle myosin. J Biol Chem (1992) 1.51
Characterization of myosin heavy chains in cultured aorta smooth muscle cells. A comparative study. J Biol Chem (1987) 1.48
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The binding of smooth muscle heavy meromyosin to actin in the presence of ATP. Effect of phosphorylation. J Biol Chem (1982) 1.43
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Calmodulin and the regulation of the actin-myosin interaction in smooth muscle and nonmuscle cells. Cell (1982) 1.37
Isolation and properties of platelet myosin light chain kinase. Biochemistry (1976) 1.37
Cloning of the cDNA encoding the myosin heavy chain of a vertebrate cellular myosin. Proc Natl Acad Sci U S A (1989) 1.34
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Phosphorylation of phospholamban by calcium-activated, phospholipid-dependent protein kinase. Stimulation of cardiac sarcoplasmic reticulum calcium uptake. J Biol Chem (1984) 1.28
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Isolation and characterization of bovine brain calcineurin: a calmodulin-stimulated protein phosphatase. Methods Enzymol (1983) 1.23
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Identification, characterization, and functional correlation of calmodulin-dependent protein phosphatase in sperm. J Cell Biol (1988) 1.19
Calcium modulation of inositol 1,4,5-trisphosphate-induced calcium release from neuroblastoma x glioma hybrid (NG108-15) microsomes. J Biol Chem (1986) 1.17
The effects of deletions in the central helix of calmodulin on enzyme activation and peptide binding. J Biol Chem (1989) 1.16
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