Published in Am J Hum Genet on July 01, 1982
Nonuniform recombination within the human beta-globin gene cluster. Am J Hum Genet (1984) 7.97
The use of restriction fragment length polymorphisms in paternity analysis. Am J Hum Genet (1986) 1.36
A strategy for using multiple linked markers for genetic counseling. Am J Hum Genet (1985) 1.08
Utility and efficiency of linked marker genes for genetic counseling. III. Proportion of informative families under linkage disequilibrium. Am J Hum Genet (1983) 0.98
2013 William Allan Award: My multifactorial journey. Am J Hum Genet (2014) 0.78
The use of multiple restriction fragment length polymorphisms in prenatal risk estimation. I. X-linked diseases. Am J Hum Genet (1985) 0.75
Construction of a genetic linkage map in man using restriction fragment length polymorphisms. Am J Hum Genet (1980) 75.25
Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation. Proc Natl Acad Sci U S A (1978) 16.54
Polymorphism of DNA sequence in the beta-globin gene region. Application to prenatal diagnosis of beta 0 thalassemia in Sardinia. N Engl J Med (1980) 3.72
Non-random association between electromorphs and inversion chromosomes in finite populations. Genet Res (1980) 3.69
PEDIG--a computer program for calculation of genotype probabilities using phenotype information. Clin Genet (1972) 3.35
Calculation of risk factors and likelihoods for familial diseases. Comput Biomed Res (1976) 2.16
Model for antenatal diagnosis of beta-thalassaemia and other monogenic disorders by molecular analysis of linked DNA polymorphisms. Nature (1980) 1.79
Prenatal diagnosis of sickle cell anemia by restriction and endonuclease analysis: HindIII polymorphisms in gamma-globin genes extend test applicability. Proc Natl Acad Sci U S A (1980) 1.71
Proportion of informative families for genetic counseling with linked marker genes. Jinrui Idengaku Zasshi (1979) 1.07
The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol (1987) 266.90
Mathematical model for studying genetic variation in terms of restriction endonucleases. Proc Natl Acad Sci U S A (1979) 41.08
MEGA2: molecular evolutionary genetics analysis software. Bioinformatics (2001) 38.50
Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. Mol Biol Evol (1993) 38.03
Identification of the cystic fibrosis gene: genetic analysis. Science (1989) 33.61
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Analysis of gene diversity in subdivided populations. Proc Natl Acad Sci U S A (1973) 26.31
Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nat Genet (1999) 17.09
Statistical studies on protein polymorphism in natural populations. I. Distribution of single locus heterozygosity. Genetics (1977) 17.08
Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection. Nature (1988) 15.05
Phylogenetic test of the molecular clock and linearized trees. Mol Biol Evol (1995) 14.60
Comparative analyses of multi-species sequences from targeted genomic regions. Nature (2003) 13.31
Gene differences between Caucasian, Negro, and Japanese populations. Science (1972) 12.11
Sampling variances of heterozygosity and genetic distance. Genetics (1974) 11.91
A new method of inference of ancestral nucleotide and amino acid sequences. Genetics (1995) 10.23
DNA polymorphism detectable by restriction endonucleases. Genetics (1981) 10.13
The theory of genetic distance and evolution of human races. Jinrui Idengaku Zasshi (1978) 8.80
Relationships between gene trees and species trees. Mol Biol Evol (1988) 8.63
New goals for the U.S. Human Genome Project: 1998-2003. Science (1998) 8.30
Nonuniform recombination within the human beta-globin gene cluster. Am J Hum Genet (1984) 7.97
DNA duplication associated with Charcot-Marie-Tooth disease type 1A. Cell (1991) 7.93
Accuracy of estimated phylogenetic trees from molecular data. II. Gene frequency data. J Mol Evol (1983) 7.45
A DNA polymorphism discovery resource for research on human genetic variation. Genome Res (1998) 7.44
Limitations of the evolutionary parsimony method of phylogenetic analysis. Mol Biol Evol (1990) 5.92
F-statistics and analysis of gene diversity in subdivided populations. Ann Hum Genet (1977) 5.89
Estimation of fixation indices and gene diversities. Ann Hum Genet (1983) 5.67
Genetic structure of human populations. II. Differentiation of blood group gene frequencies among isolated populations. Heredity (Edinb) (1966) 5.55
Positive Darwinian selection after gene duplication in primate ribonuclease genes. Proc Natl Acad Sci U S A (1998) 5.54
Maximum likelihood estimation of the number of nucleotide substitutions from restriction sites data. Genetics (1983) 5.48
Estimation of evolutionary distance between nucleotide sequences. Mol Biol Evol (1984) 5.39
High-throughput variation detection and genotyping using microarrays. Genome Res (2001) 5.24
Linkage disequilibrium in subdivided populations. Genetics (1973) 5.22
Allelic genealogy under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci. Genetics (1990) 5.11
Genetic distances and reconstruction of phylogenetic trees from microsatellite DNA. Genetics (1996) 4.55
Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection. Proc Natl Acad Sci U S A (1989) 4.52
Drift variances of heterozygosity and genetic distance in transient states. Genet Res (1975) 4.45
Molecular phylogeny and divergence times of drosophilid species. Mol Biol Evol (1995) 4.33
Pseudogenes as a paradigm of neutral evolution. Nature (1981) 4.33
Genetic distance and electrophoretic identity of proteins between taxa. J Mol Evol (1973) 4.19
Automated construction of genetic linkage maps using an expert system (MultiMap): a human genome linkage map. Nat Genet (1994) 4.19
Hirschsprung disease, associated syndromes and genetics: a review. J Med Genet (2007) 4.13
Modification of linkage intensity by natural selection. Genetics (1967) 3.99
Non-random association between electromorphs and inversion chromosomes in finite populations. Genet Res (1980) 3.69
Gene genealogy and variance of interpopulational nucleotide differences. Genetics (1985) 3.64
Infinite allele model with varying mutation rate. Proc Natl Acad Sci U S A (1976) 3.56
Estimation of average number of nucleotide substitutions when the rate of substitution varies with nucleotide. J Mol Evol (1982) 3.45
Population dynamics of sex-determining alleles in honey bees and self-incompatibility alleles in plants. Genetics (1979) 3.27
Basic fallacies in the formulation of the paternity index. Am J Hum Genet (1985) 3.18
Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21. Nat Genet (1998) 3.00
Evidence for increased recombination near the human insulin gene: implication for disease association studies. Proc Natl Acad Sci U S A (1986) 2.96
Molecular evidence for a relationship between LINE-1 elements and X chromosome inactivation: the Lyon repeat hypothesis. Proc Natl Acad Sci U S A (2000) 2.94
Probability of identical monomorphism in related species. Genet Res (1975) 2.91
Estimating the prior probability of paternity from the results of exclusion tests. Forensic Sci Int (1984) 2.91
Similarity of DNA fingerprints due to chance and relatedness. Hum Hered (1993) 2.90
Efficiencies of fast algorithms of phylogenetic inference under the criteria of maximum parsimony, minimum evolution, and maximum likelihood when a large number of sequences are used. Mol Biol Evol (2000) 2.86
Parallel genotyping of human SNPs using generic high-density oligonucleotide tag arrays. Genome Res (2000) 2.79
Genetic variability maintained by mutation and overdominant selection in finite populations. Genetics (1981) 2.79
Genic variation within and between the three major races of man, Caucasoids, Negroids, and Mongoloids. Am J Hum Genet (1974) 2.77
Genetic mapping of autosomal dominant Charcot-Marie-Tooth disease in a large French-Acadian kindred: identification of new linked markers on chromosome 17. Am J Hum Genet (1990) 2.77
The frequency distribution of lethal chromosomes in finite populations. Proc Natl Acad Sci U S A (1968) 2.76
Statistical Studies on Protein Polymorphism in Natural Populations. III. Distribution of Allele Frequencies and the Number of Alleles per Locus. Genetics (1980) 2.76
Theoretical foundation of the minimum-evolution method of phylogenetic inference. Mol Biol Evol (1993) 2.74
Letters to the editors: Lewontin-Krakauer test for neutral genes. Genetics (1975) 2.59
Models of evolution of reproductive isolation. Genetics (1983) 2.58
Phylogenetic analysis of polymorphic DNA sequences at the Adh locus in Drosophila melanogaster and its sibling species. J Mol Evol (1985) 2.48
Patterns of polymorphism and linkage disequilibrium suggest independent origins of the human growth hormone gene cluster. Proc Natl Acad Sci U S A (1984) 2.47
Interior-branch and bootstrap tests of phylogenetic trees. Mol Biol Evol (1995) 2.45
Positive Darwinian selection promotes charge profile diversity in the antigen-binding cleft of class I major-histocompatibility-complex molecules. Mol Biol Evol (1990) 2.41
Patterns of genetic variation in Mendelian and complex traits. Annu Rev Genomics Hum Genet (2000) 2.37
Testing the neutral mutation hypothesis by distribution of single locus heterozygosity. Nature (1976) 2.37
A genetic study of Hirschsprung disease. Am J Hum Genet (1990) 2.30
Accumulation of mutations in sexual and asexual populations. Genet Res (1987) 2.30
It's raining SNPs, hallelujah? Nat Genet (1998) 2.30
Evidence for reduced recombination on the nondisjoined chromosomes 21 in Down syndrome. Science (1987) 2.27
Genetic structure of human populations. I. Local differentiation of blood group gene frequencies in Japan. Heredity (Edinb) (1966) 2.26
The number of nucleotides required to determine the branching order of three species, with special reference to the human-chimpanzee-gorilla divergence. J Mol Evol (1986) 2.25
Evidence for multiple origins of the beta E-globin gene in Southeast Asia. Proc Natl Acad Sci U S A (1982) 2.24
Accuracies of ancestral amino acid sequences inferred by the parsimony, likelihood, and distance methods. J Mol Evol (1997) 2.23
Identity of genes by descent within and between populations under mutation and migration pressures. Theor Popul Biol (1972) 2.19
Positive darwinian selection observed at the variable-region genes of immunoglobulins. Mol Biol Evol (1989) 2.17
Estimation of mutation rate from rare protein variants. Am J Hum Genet (1977) 2.15
Evolution of human races at the gene level. Prog Clin Biol Res (1982) 2.13
Statistical Studies on Protein Polymorphism in Natural Populations II. Gene Differentiation between Populations. Genetics (1978) 2.13
Note on genetic drift and estimation of effective population size. Genetics (1984) 2.07
Relative efficiencies of the maximum parsimony and distance-matrix methods in obtaining the correct phylogenetic tree. Mol Biol Evol (1988) 2.03
Multiplex PCR of three dinucleotide repeats in the Prader-Willi/Angelman critical region (15q11-q13): molecular diagnosis and mechanism of uniparental disomy. Hum Mol Genet (1993) 2.02
Total number of individuals affected by a single deleterious mutation in a finite population. Am J Hum Genet (1972) 1.98
Small-sample tests of episodic adaptive evolution: a case study of primate lysozymes. Mol Biol Evol (1997) 1.97
Linkage modifications and sex difference in recombination. Genetics (1969) 1.96
Stable linkage disequilibrium without epistasis in subdivided populations. Theor Popul Biol (1974) 1.93
Extinction time of deleterious mutant genes in large populations. Theor Popul Biol (1971) 1.87
Polymorphism and evolution of influenza A virus genes. Mol Biol Evol (1986) 1.86
Gene duplication and nucleotide substitution in evolution. Nature (1969) 1.85
Efficiencies of different genes and different tree-building methods in recovering a known vertebrate phylogeny. Mol Biol Evol (1996) 1.84
Recombination within and between the human insulin and beta-globin gene loci. Proc Natl Acad Sci U S A (1983) 1.82
Polymorphic DNA haplotypes at the LDL receptor locus. Am J Hum Genet (1989) 1.82
Allele frequency distributions in pooled DNA samples: applications to mapping complex disease genes. Genome Res (1998) 1.81
Mean and variance of FST in a finite number of incompletely isolated populations. Theor Popul Biol (1977) 1.79
Molecular characterization of two proximal deletion breakpoint regions in both Prader-Willi and Angelman syndrome patients. Am J Hum Genet (1995) 1.78