Published in J Exp Med on January 01, 1981
Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure. Proc Natl Acad Sci U S A (1987) 12.15
Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1. Proc Natl Acad Sci U S A (1991) 2.88
Molecular cloning of the human T-lymphocyte surface CD2 (T11) antigen. Proc Natl Acad Sci U S A (1986) 2.76
CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells. Proc Natl Acad Sci U S A (1988) 2.46
Monoclonal antibody analysis of human T lymphocyte subpopulations exhibiting autologous mixed lymphocyte reaction. Proc Natl Acad Sci U S A (1981) 2.16
The structure of the human CD2 gene and its expression in transgenic mice. EMBO J (1988) 2.00
T cell stimulation via the erythrocyte receptor. Synergism between monoclonal antibodies and phorbol myristate acetate without changes of free cytoplasmic Ca++ levels. J Exp Med (1986) 1.68
Cellular and molecular mechanisms for reduced interleukin 4 and interferon-gamma production by neonatal T cells. J Clin Invest (1991) 1.64
Similarities in sequences and cellular expression between rat CD2 and CD4 antigens. J Exp Med (1987) 1.57
Distinct patterns of transmembrane calcium flux and intracellular calcium mobilization after differentiation antigen cluster 2 (E rosette receptor) or 3 (T3) stimulation of human lymphocytes. J Clin Invest (1986) 1.53
Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells. Proc Natl Acad Sci U S A (1989) 1.50
Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation. Proc Natl Acad Sci U S A (1988) 1.49
Development and function of T cells in mice with a disrupted CD2 gene. EMBO J (1992) 1.46
Suppression of human T-cell mitogenesis and E-rosette formation by the monoclonal antibody OKT11A. Immunology (1981) 1.44
The cell surface molecule recognized by the erythrocyte receptor of T lymphocytes. Identification and partial characterization using a monoclonal antibody. J Exp Med (1985) 1.44
Rosetting of activated human T lymphocytes with autologous erythrocytes. Definition of the receptor and ligand molecules as CD2 and lymphocyte function-associated antigen 3 (LFA-3). J Exp Med (1987) 1.31
Activation of rat T lymphocytes by anti-CD2 monoclonal antibodies. J Exp Med (1988) 1.26
Direct evidence for a receptor-ligand interaction between the T-cell surface antigen CD2 and lymphocyte-function-associated antigen 3. Proc Natl Acad Sci U S A (1987) 1.21
Immunopathology of cutaneous T-cell lymphomas. Am J Pathol (1985) 1.20
Anti-Ia reactivity in sera from patients with systemic lupus erythematosus. J Clin Invest (1982) 1.19
Heterogeneity of concanavalin A-induced suppressor T cells in man defined with monoclonal antibodies. Clin Exp Immunol (1982) 1.19
Activation of T lymphocytes by immobilized monoclonal antibodies to CD3. Regulatory influences of monoclonal antibodies to additional T cell surface determinants. J Clin Invest (1988) 1.18
CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration. EMBO J (1993) 1.17
Phenotypic expression of T lymphocytes in thymus and peripheral lymphoid tissues. Am J Pathol (1985) 1.16
A 3' transcriptional enhancer regulates tissue-specific expression of the human CD2 gene. EMBO J (1990) 1.14
Lymphomatoid papulosis. A cutaneous proliferation of activated helper T cells expressing Hodgkin's disease-associated antigens. Am J Pathol (1985) 1.13
Expression of T-cell antigens on Reed-Sternberg cells in a subset of patients with nodular sclerosing and mixed cellularity Hodgkin's disease. Am J Pathol (1988) 1.11
Monoclonal antibodies which react with bovine T-lymphocyte antigens and induce blastogenesis: tissue distribution and functional characteristics of the target antigens. Immunology (1988) 1.07
Bovine pan T-cell monoclonal antibodies reactive with a molecule similar to CD2. Immunology (1988) 1.06
Induction of specific nonresponsiveness in unprimed human T cells by anti-CD3 antibody and alloantigen. J Exp Med (1990) 1.04
Characterization of the killer cell generated in the autologous mixed leukocyte reaction. J Exp Med (1983) 1.02
Low-grade lymphomas. Expression of developmentally regulated B-cell antigens. Am J Pathol (1984) 1.01
Selective blockade of human natural killer cells by a monoclonal antibody. Proc Natl Acad Sci U S A (1982) 1.01
Deletion analysis of the human CD2 gene locus control region in transgenic mice. Nucleic Acids Res (1991) 0.97
Immunohistology of the thymus in bone marrow transplant recipients. Am J Pathol (1986) 0.95
An immunohistological study of human hepatic graft-versus-host disease. Clin Exp Immunol (1985) 0.95
Chromatin configuration of the human CD2 gene locus during T-cell development. Proc Natl Acad Sci U S A (1989) 0.93
Ecto-5'-nucleotidase activity in human T cell subsets. Decreased numbers of ecto-5'-nucleotidase positive cells from both OKT4+ and OKT8+ cells in patients with hypogammaglobulinemia. J Clin Invest (1983) 0.93
Changes in rectal leucocytes after allogeneic bone marrow transplantation. Clin Exp Immunol (1987) 0.90
Anti-Ia antibody in the sera of normal subjects after in vivo antigenic stimulation. J Exp Med (1982) 0.90
Monoclonal antibody defined T cell subsets and autologous mixed lymphocyte reaction in Down's syndrome. Clin Exp Immunol (1983) 0.90
Role in T-cell activation for HLA class I molecules from accessory cells: further distinction between activation signals delivered to T cells via CD2 and CD3 molecules. Proc Natl Acad Sci U S A (1987) 0.90
Intracellular mediators regulate CD2 lateral diffusion and cytoplasmic Ca2+ mobilization upon CD2-mediated T cell activation. Biophys J (1995) 0.87
Ontogenic development of T and B cells and non-lymphoid cells in the white pulp of human spleen. Immunology (1986) 0.86
Isolation and partial characterization of a novel subset of human T lymphocytes defined by monoclonal antibodies. Immunology (1982) 0.83
Restricted expression of CD2 among subsets of sheep thymocytes and T lymphocytes. Immunology (1989) 0.83
Ligand-induced association between the T-cell antigen receptor and two glycoproteins. Proc Natl Acad Sci U S A (1989) 0.82
Retroviral activation of interleukin 2 gene in a gibbon ape T cell lymphoma line. J Exp Med (1986) 0.82
Characterization of the suppressor cell activity in human cord blood lymphocytes. J Clin Invest (1981) 0.81
Analysis with monoclonal antibodies of human lymphoid cells forming rosettes with rabbit red blood cells. Clin Exp Immunol (1983) 0.81
IgE Fc receptor positive T and B lymphocytes in patients with the hyper IgE syndrome. Clin Exp Immunol (1985) 0.81
Selective activation of gamma/delta + T cell clones by single anti-CD2 antibodies. J Exp Med (1991) 0.79
Dermatopathic lymphadenopathy. An immunophenotypic comparison of cases associated and unassociated with mycosis fungoides. Am J Pathol (1986) 0.79
Five antigens on human T cells detected by mouse monoclonal antibodies. Clin Exp Immunol (1984) 0.78
Detection of lymphocytes in malignant gliomas by monoclonal antibodies. J Neurol Neurosurg Psychiatry (1983) 0.78
Immunologic function in a cohort of human immunodeficiency virus type 1-seropositive and -negative healthy homosexual men. J Clin Microbiol (1991) 0.77
Modulation of T-lymphocyte differentiation antigens: potential relevance for multiple sclerosis. Proc Natl Acad Sci U S A (1982) 0.77
Immunological studies in patients with isolated growth hormone deficiency. Clin Exp Immunol (1983) 0.77
Hydrocortisone enhances total IgE levels--but not the synthesis of allergen-specific IgE--in a monocyte-dependent manner. Clin Exp Immunol (1995) 0.76
Murine anti-lymphocyte monoclonal antibodies fail to act as opsonins for allogeneic human peripheral blood polymorphonuclear phagocytes. Clin Exp Immunol (1984) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A. J Immunol (1975) 47.77
Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells. J Exp Med (1972) 24.43
Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell (1978) 14.82
Discrete stages of human intrathymic differentiation: analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage. Proc Natl Acad Sci U S A (1980) 11.23
Monoclonal antibodies defining distinctive human T cell surface antigens. Science (1979) 10.50
X-ray intensifying screens greatly enhance the detection by autoradiography of the radioactive isotopes 32P and 125I. Anal Biochem (1978) 10.28
An improved rosetting assay for detection of human T lymphocytes. J Immunol Methods (1974) 6.54
A monoclonal antibody with selective reactivity with functionally mature human thymocytes and all peripheral human T cells. J Immunol (1979) 6.08
Cell surface immunoglobulin. II. Isolation and characterization of immunoglobulin from mouse splenic lymphocytes. J Exp Med (1971) 5.80
A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur J Immunol (1979) 5.17
Identification of a p69,71 complex expressed on human T cells sharing determinants with B-type chronic lymphatic leukemic cells. J Exp Med (1980) 2.89
Binding of sheep erythrocytes to human lymphocytes. A probable marker of T lymphocytes. Scand J Immunol (1972) 2.87
A human thymus-leukemia antigen defined by hybridoma monoclonal antibodies. Proc Natl Acad Sci U S A (1979) 1.94
Monoclonal antibodies to Chlamydia trachomatis: antibody specificities and antigen characterization. J Immunol (1982) 8.61
Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation (1987) 7.14
Culture-independent diagnosis of Chlamydia trachomatis using monoclonal antibodies. N Engl J Med (1984) 6.08
L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L. Biochem J (1982) 5.67
The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy (2001) 5.65
Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers. N Engl J Med (2001) 5.59
Serological classification of Neisseria gonorrhoeae with monoclonal antibodies. Infect Immun (1982) 5.54
Serological classification of Neisseria gonorrhoeae with use of monoclonal antibodies to gonococcal outer membrane protein I. J Infect Dis (1984) 5.40
A proposed nomenclature for the virion proteins of oncogenic RNA viruses. Virology (1974) 5.01
The isolation of hybrid cell lines producing monoclonal antibodies against the p15(E) protein of ecotropic murine leukemia viruses. Virology (1979) 4.59
Effect of intravenous streptokinase on left ventricular function and early survival after acute myocardial infarction. N Engl J Med (1987) 4.08
Major-histocompatibility-complex class I alleles and antigens in hematopoietic-cell transplantation. N Engl J Med (2001) 3.98
A review of the MHC genetics of rheumatoid arthritis. Genes Immun (2004) 3.77
Human hepatic lipase. Cloned cDNA sequence, restriction fragment length polymorphisms, chromosomal localization, and evolutionary relationships with lipoprotein lipase and pancreatic lipase. J Biol Chem (1988) 3.74
Definition of a common leukocyte cell-surface antigen (Lp95-150) associated with diverse cell-mediated immune functions. J Immunol (1983) 3.70
Endothelial cells of hematopoietic origin make a significant contribution to adult blood vessel formation. Circ Res (2000) 3.64
The electrophoretically 'slow' and 'fast' forms of the alpha 2-macroglobulin molecule. Biochem J (1979) 3.58
Human T cell activation. II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen). J Exp Med (1985) 3.48
4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses. J Exp Med (1997) 3.31
Detection of avian and mammalian oncogenic RNA viruses (oncornaviruses) by immunofluorescence. Cancer Res (1972) 3.23
Monoclonal antibodies to cytomegalovirus: rapid identification of clinical isolates and preliminary use in diagnosis of cytomegalovirus pneumonia. Infect Immun (1982) 3.22
Radiolabeled-antibody therapy of B-cell lymphoma with autologous bone marrow support. N Engl J Med (1993) 3.18
Optimizing outcome after unrelated marrow transplantation by comprehensive matching of HLA class I and II alleles in the donor and recipient. Blood (1998) 3.06
Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus. Proc Natl Acad Sci U S A (1990) 2.88
Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program. N Engl J Med (1993) 2.85
Chromatographic separation and antigenic analysis of proteins of the oncornaviruses. II. Mammalian leukemia-sarcoma viruses. J Virol (1972) 2.84
Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells. Mol Cell Biol (1986) 2.76
Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1. J Exp Med (1993) 2.71
Monoclonal antibodies against murine leukemia viruses: identification of six antigenic determinants on the p 15(E) and gp70 envelope proteins. Virology (1979) 2.62
Effect of HLA compatibility on engraftment of bone marrow transplants in patients with leukemia or lymphoma. N Engl J Med (1989) 2.61
Monoclonal antibodies to herpes simplex viruses: use in antigenic typing and rapid diagnosis. J Infect Dis (1983) 2.60
Predictors of self-reported adherence in persons living with HIV disease. AIDS Patient Care STDS (1999) 2.55
Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis. J Exp Med (2000) 2.54
Typing of clinical herpes simplex virus isolates with mouse monoclonal antibodies to herpes simplex virus types 1 and 2: comparison with type-specific rabbit antisera and restriction endonuclease analysis of viral DNA. J Clin Microbiol (1983) 2.50
Antibodies to Tp67 and Tp44 augment and sustain proliferative responses of activated T cells. J Immunol (1985) 2.46
Transcription of mouse mammary tumor virus genes in tissues from high and low tumor incidence mouse strains. J Mol Biol (1973) 2.45
B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells. Cell (1987) 2.44
Cystatin, a protein inhibitor of cysteine proteinases. Improved purification from egg white, characterization, and detection in chicken serum. Biochem J (1983) 2.42
Cell surface antigens of human melanoma identified by monoclonal antibody. Proc Natl Acad Sci U S A (1979) 2.40
Bone marrow transplants from unrelated donors for patients with chronic myeloid leukemia. N Engl J Med (1998) 2.36
Oncogenicity of AKR endogenous leukemia viruses. J Virol (1978) 2.31
Marrow transplantation from related donors other than HLA-identical siblings. N Engl J Med (1985) 2.30
Renal artery stenosis and peripheral vascular disease: implications for ACE inhibitor therapy. Lancet (1990) 2.29
Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells. J Exp Med (1994) 2.29
The classification, diagnosis and management of the hypertensive disorders of pregnancy: A revised statement from the ISSHP. Pregnancy Hypertens (2014) 2.29
Group-specific viral antigens in the milk and tissues of mice naturally infected with mammary tumor virus or Gross leukemia virus. Virology (1968) 2.26
Should HLA mismatch acceptability for sensitized transplant candidates be determined at the high-resolution rather than the antigen level? Am J Transplant (2015) 2.24
Relationships between perception of engagement with health care provider and demographic characteristics, health status, and adherence to therapeutic regimen in persons with HIV/AIDS. AIDS Patient Care STDS (2000) 2.21
Common properties of the oncogenic RNA viruses (oncornaviruses). Virology (1970) 2.20
Monoclonal antibody analysis of human T lymphocyte subpopulations exhibiting autologous mixed lymphocyte reaction. Proc Natl Acad Sci U S A (1981) 2.16
The events of primary T cell activation can be staged by use of Sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1. J Immunol (1985) 2.14
Identification and functional characterization of two distinct epitopes on the human T cell surface protein Tp50. J Immunol (1983) 2.13
Antibodies to common leukocyte antigen p220 influence human T cell proliferation by modifying IL 2 receptor expression. J Immunol (1985) 2.11
A phase I/II trial of iodine-131-tositumomab (anti-CD20), etoposide, cyclophosphamide, and autologous stem cell transplantation for relapsed B-cell lymphomas. Blood (2000) 2.11
A DNase I-hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer. J Immunol (1992) 2.04
Monoclonal antibodies for diagnosis of infectious diseases in humans. Science (1983) 2.02
Marrow transplantation for chronic myeloid leukemia: a randomized study comparing cyclophosphamide and total body irradiation with busulfan and cyclophosphamide. Blood (1994) 1.98
Acute renal failure following cardiac surgery: incidence, outcomes and risk factors. Aust N Z J Med (1995) 1.97
A 44 kilodalton cell surface homodimer regulates interleukin 2 production by activated human T lymphocytes. J Immunol (1986) 1.95
Maternal-fetal disparity in HLA class II alloantigens and the pregnancy-induced amelioration of rheumatoid arthritis. N Engl J Med (1993) 1.92
Antibody to leukemia virus: widespread occurrence in inbred mice. Science (1974) 1.91
Effect of HLA incompatibility on graft-versus-host disease, relapse, and survival after marrow transplantation for patients with leukemia or lymphoma. Hum Immunol (1990) 1.91
Graft-versus-host disease and survival in patients with aplastic anemia treated by marrow grafts from HLA-identical siblings. Beneficial effect of a protective environment. N Engl J Med (1983) 1.89
Nomenclature for factors of the HLA system, 2002. Tissue Antigens (2002) 1.89
Antibody binding to CD5 (Tp67) and Tp44 T cell surface molecules: effects on cyclic nucleotides, cytoplasmic free calcium, and cAMP-mediated suppression. J Immunol (1986) 1.89
Mammary tumour virus specific nucleotide sequences in mouse DNA. Nat New Biol (1972) 1.87
Endogenous ecotropic mouse type C viruses deficient in replication and production of XC plaques. J Virol (1976) 1.87
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Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts. Blood (1985) 1.81
Mortality hazard functions as related to neutropenia at different times after marrow transplantation. Blood (1996) 1.81
Allogeneic peripheral blood stem cell transplantation may be associated with a high risk of chronic graft-versus-host disease. Blood (1997) 1.80
Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling. J Biol Chem (1998) 1.79
Hereditary C2 deficiency: Genetic studies and association with the HL-A system. J Exp Med (1975) 1.75
Serological analysis of the deoxyribonucleic acid polymerase of avian oncornaviruses. II. Comparison of avian deoxyribonucleic acid polymerases. J Virol (1972) 1.75
Detection of maternal cells in human umbilical cord blood using fluorescence in situ hybridization. Blood (1995) 1.75
Oncornaviruses produced by murine leukemia cells in culture. Virology (1977) 1.73
Alloantigen-specific cytotoxic and suppressor T lymphocytes are derived from phenotypically distinct precursors. J Immunol (1983) 1.73
Topological mapping of murine leukemia virus proteins by competition-binding assays with monoclonal antibodies. Virology (1980) 1.72
Rapid screening of T-cell receptor (TCR) variable gene usage by multiplex PCR: application for assessment of clonal composition. Tissue Antigens (1999) 1.71
Specific genomic markers for the HLA-DQ subregion discriminate between DR4+ insulin-dependent diabetes mellitus and DR4+ seropositive juvenile rheumatoid arthritis. J Exp Med (1986) 1.69
Suggestive linkage of the parathyroid receptor type 1 to osteoporosis. J Bone Miner Res (1999) 1.69
Phase II trial of 131I-B1 (anti-CD20) antibody therapy with autologous stem cell transplantation for relapsed B cell lymphomas. Lancet (1995) 1.69
Quantitative determination of bone marrow transplant engraftment using fluorescent polymerase chain reaction primers for human identity markers. Blood (1995) 1.68
Deletion mapping and expression in Escherichia coli of the large genomic segment of a birnavirus. Virology (1987) 1.68
Association of HLA-C disparity with graft failure after marrow transplantation from unrelated donors. Blood (1997) 1.65
Enhanced expression of HLA antigens and beta 2-microglobulin on interferon-treated human lymphoid cells. Eur J Immunol (1979) 1.65
Marrow transplantation for chronic myeloid leukemia: the influence of plasma busulfan levels on the outcome of transplantation. Blood (1997) 1.64