Published in Drug Metab Rev on January 01, 1982
Dioxins and dibenzofurans in adipose tissue of US Vietnam veterans and controls. Am J Public Health (1991) 1.53
Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer. Proc Natl Acad Sci U S A (1988) 1.50
The role of structure in the disposition of halogenated aromatic xenobiotics. Environ Health Perspect (1985) 1.23
Laboratory and human studies on polychlorinated biphenyls (PCBs) and related compounds. Environ Health Perspect (1985) 1.14
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) as a potent and persistent thyroxine agonist: a mechanistic model for toxicity based on molecular reactivity. Environ Health Perspect (1985) 0.96
Mechanism of action of toxic halogenated aromatics. Environ Health Perspect (1985) 0.87
Mechanisms of the biological effects of PCBs, polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in experimental animals. Environ Health Perspect (1985) 0.83
Induction of a chloracne phenotype in an epidermal equivalent model by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on aryl hydrocarbon receptor activation and is not reproduced by aryl hydrocarbon receptor knock down. J Dermatol Sci (2013) 0.76
The suppression of malarial parasitaemia by pyrimethamine in combination with dapsone or sulphormethoxine. Trans R Soc Trop Med Hyg (1969) 2.06
Nonfunctional, nonchromaffin paragangliomas of the retroperitoneum. Cancer (1969) 2.05
An in-vitro system for determining the activity of compounds against the intracellular amastigote form of Leishmania donovani. J Antimicrob Chemother (1984) 1.83
A comparative study of Entamoeba histolytica (NIH :200, HK9, etc.), "E. histolytica-like" and other morphologically identical amoebae using isoenzyme electrophoresis. Trans R Soc Trop Med Hyg (1980) 1.73
The toxicokinetics and metabolism of polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) and their relevance for toxicity. Crit Rev Toxicol (1994) 1.35
Comparisons of estimated human body burdens of dioxinlike chemicals and TCDD body burdens in experimentally exposed animals. Environ Health Perspect (1995) 1.27
A potential endogenous ligand for the aryl hydrocarbon receptor has potent agonist activity in vitro and in vivo. Arch Biochem Biophys (2006) 1.26
Flavone antagonists bind competitively with 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD) to the aryl hydrocarbon receptor but inhibit nuclear uptake and transformation. Mol Pharmacol (1999) 1.24
Role of estrogen receptor alpha in hematopoietic stem cell development and B lymphocyte maturation in the male mouse. Endocrinology (2000) 1.22
Tumors of the peripheral nervous system. Hum Pathol (1970) 1.21
Congener-specific levels of dioxins and dibenzofurans in U.S. food and estimated daily dioxin toxic equivalent intake. Environ Health Perspect (1994) 1.20
Thioacetamide-induced hepatic necrosis. I. Involvement of the mixed-function oxidase enzyme system. J Pharmacol Exp Ther (1977) 1.19
The aryl hydrocarbon receptor is a regulator of cigarette smoke induction of the cyclooxygenase and prostaglandin pathways in human lung fibroblasts. Am J Physiol Lung Cell Mol Physiol (2005) 1.17
Protein-DNA interactions at a dioxin-responsive enhancer. Evidence that the transformed Ah receptor is heteromeric. J Biol Chem (1990) 1.16
Lymphocyte stem cell alterations following perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Mol Pharmacol (1989) 1.16
The activity of alkyl phosphorylcholines and related derivatives against Leishmania donovani. Biochem Pharmacol (1987) 1.15
The examination and quantitation of tissue cytosolic receptors for 2,3,7,8-tetrachlorodibenzo-p-dioxin using hydroxylapatite. Anal Biochem (1982) 1.15
Distribution, excretion, and metabolism of 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL/6J, DBA/2J, and B6D2F1/J mice. Drug Metab Dispos (1983) 1.14
Anti-leishmanial effect of allopurinol ribonucleoside and the related compounds, allopurinol, thiopurinol, thiopurinol ribonucleoside, and of formycin B, sinefungin and the lepidine WR6026. Trans R Soc Trop Med Hyg (1985) 1.14
Malaria-infected erythrocytes serve as biological standards to ensure reliable and consistent scoring of micronucleated erythrocytes by flow cytometry. Mutat Res (2000) 1.13
Estrogen receptor alpha is necessary in thymic development and estradiol-induced thymic alterations. J Immunol (1999) 1.13
Decrease in milk and blood dioxin levels over two years in a mother nursing twins: estimates of decreased maternal and increased infant dioxin body burden from nursing. Chemosphere (1996) 1.12
Metabolism of thioacetamide and thioacetamide S-oxide by rat liver microsomes. Drug Metab Dispos (1978) 1.10
Thymic alterations induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin are strictly dependent on aryl hydrocarbon receptor activation in hemopoietic cells. J Immunol (1998) 1.09
In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids. Cancer Res (1981) 1.08
Interactions of cadmium and selenium in rat plasma in vivo and in vitro. Biochim Biophys Acta (1976) 1.06
Memory loss due to hippocampal lesions. Report of a case. Arch Neurol (1969) 1.05
The aryl hydrocarbon receptor has a role in the in vivo maturation of murine bone marrow B lymphocytes and their response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol (2000) 1.03
2,3,7,8-Tetrachlorodibenzo-p-dioxin tissue distribution, excretion, and effects on clinical chemical parameters in guinea pigs. Toxicol Appl Pharmacol (1979) 1.00
Thioacetamide-induced hepatic necrosis. II. Pharmacokinetics of thioacetamide and thioacetamide-S-oxide in the rat. J Pharmacol Exp Ther (1979) 0.99
Immunization against protozoal diseases. Br Med Bull (1969) 0.99
Polyamine deficiency reduces the rate of DNA replication fork movement in Escherichia coli. Nature (1978) 0.99
Impairment of prothymocyte activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Immunol (1990) 0.99
Identification of the major protein adduct formed in rat liver after thioacetamide administration. Cancer Res (1981) 0.98
Pasteurella pneumotropica infection resulting from a cat bite. Am J Clin Pathol (1969) 0.98
A comparative study of susceptibility of inbred and outbred mouse strains compared with hamsters to infection with New World cutaneous leishmaniases. Parasitology (1983) 0.98
Studies of the mechanism of metabolism of thioacetamide s-oxide by rat liver microsomes. Mol Pharmacol (1983) 0.98
The effect of antibiotics of the neomycin group on experimental cutaneous leishmaniasis. Ann Trop Med Parasitol (1968) 0.97
Distribution of the thrombomodulin antigen in the rabbit vasculature. Lab Invest (1986) 0.97
Hemopoietic progenitor cells are sensitive targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL/6J mice. Toxicol Sci (2000) 0.96
Characterization of multiple forms of the Ah receptor: comparison of species and tissues. Biochemistry (1989) 0.96
Biotransformation of phenol to hydroquinone and catechol by rat liver microsomes. Mol Pharmacol (1983) 0.96
Chagas disease of the colon and rectum. Gut (1969) 0.96
Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene- and cigarette smoke condensate-induced cytogenetic damage in vivo. Carcinogenesis (2001) 0.96
A double-blind clinical trial of the treatment of cutaneous leishmaniasis with paromomycin ointment. Trans R Soc Trop Med Hyg (1991) 0.95
Experimental studies on Entamoeba with reference to speciation. Adv Parasitol (1966) 0.94
Detection of CYP1A1 protein in human liver and induction by TCDD in precision-cut liver slices incubated in dynamic organ culture. Carcinogenesis (1998) 0.94
Changes in thyroid hormones and thyroxine glucuronidation in hamsters compared with rats following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol (1987) 0.93
Toxicology of thiono-sulfur compounds. Annu Rev Pharmacol Toxicol (1982) 0.93
Prothymocyte activity is reduced by perinatal 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure. J Pharmacol Exp Ther (1990) 0.93
Cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Evidence for a homologous nature among various mammalian species. Mol Pharmacol (1984) 0.93
Heterogeneity of the rat hepatic Ah receptor and evidence for transformation in vitro and in vivo. J Biol Chem (1987) 0.92
Stimulation of deoxyribonucleic acid replication fork movement by spermidine analogs in polyamine-deficient Escherichia coli. J Bacteriol (1980) 0.92
Influence of aromatic hydrocarbon receptor-mediated events on the genotoxicity of cigarette smoke condensate. Carcinogenesis (1998) 0.91
Selective inhibition of Leishmania dihydrofolate reductase and Leishmania growth by 5-benzyl-2,4-diaminopyrimidines. Mol Biochem Parasitol (1988) 0.91
Function of estrogen receptor tyrosine 537 in hormone binding, DNA binding, and transactivation. Biochemistry (1999) 0.91
Studies of the metabolism of carbon disulfide by rat liver microsomes. Life Sci (1974) 0.91
Dioxins and the Ah receptor. Am J Ind Med (1989) 0.91
Hepatic carbonyl sulfide metabolism. Biochem Biophys Res Commun (1979) 0.90
Studies on the mechanism of toxicity and of development of tolerance to the pulmonary toxin, alpha-naphthylthiourea (ANTU). Drug Metab Dispos (1976) 0.90
Metabolism of alpha-naphthylthiourea by rat liver and rat lung microsomes. Toxicol Appl Pharmacol (1980) 0.90
Agonist but not antagonist ligands induce conformational change in the mouse aryl hydrocarbon receptor as detected by partial proteolysis. Mol Pharmacol (2003) 0.90
Microsomal activation of thioacetamide-S-oxide to a metabolite(s) that covalently binds to calf thymus DNA and other polynucleotides. Chem Biol Interact (1981) 0.90
Interaction of hexachlorobenzene with the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in vitro and in vivo. Evidence that hexachlorobenzene is a weak Ah receptor agonist. Arch Biochem Biophys (1989) 0.89
Molecular determinants of species-specific agonist and antagonist activity of a substituted flavone towards the aryl hydrocarbon receptor. Arch Biochem Biophys (2008) 0.89
Aryl hydrocarbon receptor activation in genital tubercle, palate, and other embryonic tissues in 2,3,7, 8-tetrachlorodibenzo-p-dioxin-responsive lacZ mice. Toxicol Appl Pharmacol (1998) 0.89
Bacterial metabolism of thiamine. 3. Metabolism of thiamine to 3-(2'-methyl-4'-amino-5'-pyrimidylmethyl)-4-methyl-thiazole-5-acetic acid (thiamine acetic acid) by a flavoprotein isolated from a soil microorganism. J Biol Chem (1970) 0.89
The amoebicidal activity and toxicity of natural emetine, (plus or minus)-2-dehydroemetine and (--)-2-dehydroemetine. Ann Trop Med Parasitol (1968) 0.89
Dexamethasone, beta-estradiol, and 2,3,7,8-tetrachlorodibenzo-p-dioxin elicit thymic atrophy through different cellular targets. Toxicol Appl Pharmacol (1994) 0.89
A single dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin produces a time- and dose-dependent alteration in the murine bone marrow B-lymphocyte maturation profile. Toxicol Sci (2000) 0.89
Indirect haemagglutination test for Chagas' disease, with a simple method for survey work. Rev Inst Med Trop Sao Paulo (1971) 0.89
Effect of TCDD exposure on CYP1A1 and CYP1B1 expression in explant cultures of human endometrium. Toxicol Sci (2001) 0.88
Alternate immune system targets for TCDD: lymphocyte stem cells and extrathymic T-cell development. Exp Clin Immunogenet (1994) 0.88
Studies of the enzymic mechanism of the metabolism of diethyl 4-nitrophenyl phosphorothionate (parathion) by rat liver microsomes. Biochem J (1967) 0.88
Antileishmanial effects of clofazimine and other antimycobacterial agents. Ann Trop Med Parasitol (1989) 0.88
Metabolism of acrylonitrile by isolated rat hepatocytes. Cancer Res (1983) 0.87
Selective inhibition of polymorphonuclear neutrophil activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol (1989) 0.87
Studies of carbonyl sulfide toxicity: Metabolism by carbonic anhydrase. Toxicol Appl Pharmacol (1980) 0.87
Identification of potential aryl hydrocarbon receptor antagonists in green tea. Chem Res Toxicol (2003) 0.87
Transformation of the aryl hydrocarbon receptor to a DNA-binding form is accompanied by release of the 90 kDa heat-shock protein and increased affinity for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochem J (1993) 0.87
Immunization against Trypanosoma cruzi using killed antigens and with saponin as adjuvant. Acta Trop (1977) 0.86
Inhibition of hepatic mixed-function oxidase activity in vitro and in vivo by various thiono-sulfur-containing compounds. Biochem Pharmacol (1975) 0.86
Human body burden of polychlorinated dibenzofurans associated with toxicity based on the yusho and yucheng incidents. Fundam Appl Toxicol (1990) 0.86
Two major human allergenic sites on ragweed pollen allergen antigen E identified by using monoclonal antibodies. J Immunol (1986) 0.86
Experimental amoebiasis and the development of anti-amoebic compounds. Parasitology (1983) 0.86
Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated hepatotoxicity in C57BL/6J and DBA/2J mice. J Toxicol Environ Health (1991) 0.85
Canaliculus reconstruction with homologous vein graft. Am J Ophthalmol (1966) 0.85
The toxicity of repeated exposures to rolipram, a type IV phosphodiesterase inhibitor, in rats. Pharmacol Toxicol (1996) 0.85
Oxygen-18 studies on the chemical mechanisms of the mixed function oxidase catalyzed desulfuration and dearylation reactions of parathion. J Pharmacol Exp Ther (1971) 0.85
Inactivation of purified rat liver cytochrome P-450 by chloramphenicol. Mol Pharmacol (1980) 0.85
alpha-Naphthoflavone antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced murine lymphocyte ethoxyresorufin-O-deethylase activity and immunosuppression. Mol Pharmacol (1987) 0.85
Congenital defect of the atlantooccipital joint in a Holstein-Friesian calf. Cornell Vet (1972) 0.84
Toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in larval and adult forms of Rana catesbeiana. Bull Environ Contam Toxicol (1976) 0.84
Tissue distribution, excretion, and metabolism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the Golden Syrian hamster. Toxicol Appl Pharmacol (1980) 0.84
Proceedings: Attempts to infect inbred strains of rats and mice with Entamoeba histolytica. Trans R Soc Trop Med Hyg (1975) 0.84