Published in J Clin Invest on October 01, 1982
Pathogenesis of osteoporosis: concepts, conflicts, and prospects. J Clin Invest (2005) 5.19
Strategies for prevention of osteoporosis and hip fracture. BMJ (1991) 3.78
Genetic determinants of bone mass in adults. A twin study. J Clin Invest (1987) 3.23
Levothyroxine dose and risk of fractures in older adults: nested case-control study. BMJ (2011) 2.97
Determinants of bone density in normal women: risk factors for future osteoporosis? BMJ (1989) 2.07
Disorders of bone remodeling. Annu Rev Pathol (2011) 2.05
Rates of bone loss in the appendicular and axial skeletons of women. Evidence of substantial vertebral bone loss before menopause. J Clin Invest (1986) 2.01
Vertebral fractures in steroid dependent asthma and involutional osteoporosis: a comparative study. Thorax (1991) 1.86
Osteoporosis, falls, and age in fracture of the proximal femur. Br Med J (Clin Res Ed) (1987) 1.81
Increase in serum bone gamma-carboxyglutamic acid protein with aging in women. Implications for the mechanism of age-related bone loss. J Clin Invest (1983) 1.69
Physical fitness is a major determinant of femoral neck and lumbar spine bone mineral density. J Clin Invest (1986) 1.63
Correlations of dual-energy X-ray absorptiometry, quantitative computed tomography, and single photon absorptiometry with spinal and non-spinal fractures. Osteoporos Int (1996) 1.55
Improvements in general health among the elderly: a factor in the rising incidence of hip fractures? J Epidemiol Community Health (1988) 1.26
Bone changes occurring spontaneously and caused by estrogen in early postmenopausal women: a local or generalised phenomenon? Br Med J (Clin Res Ed) (1986) 1.22
Bone mineral density after adjuvant chemotherapy for premenopausal breast cancer. Br J Cancer (1990) 1.16
Effects of low dose corticosteroids on bone mass in rheumatoid arthritis: a longitudinal study. Ann Rheum Dis (1989) 1.05
Architecture and distribution of cancellous bone yield vertebral fracture clues. A histomorphometric analysis of the complete spinal column from 40 autopsy specimens. Arch Orthop Trauma Surg (1996) 1.05
Age and disease-related changes in the mineral of bone. Calcif Tissue Int (1993) 1.05
Hip fracture types in men and women change differently with age. BMC Geriatr (2010) 0.98
Overview of osteoporosis. West J Med (1991) 0.97
Drivers of age-related inflammation and strategies for healthspan extension. Immunol Rev (2015) 0.94
Body mass index and bone loss among postmenopausal women: the 10-year follow-up of the OSTPRE cohort. J Bone Miner Metab (2011) 0.94
Serum levels of insulin-like growth factor (IGF); IGF-binding proteins-3, -4, and -5; and their relationships to bone mineral density and the risk of vertebral fractures in postmenopausal women. Calcif Tissue Int (2006) 0.93
Selective targeting of RANK signaling pathways as new therapeutic strategies for osteoporosis. Expert Opin Ther Targets (2010) 0.92
Age-related changes in female femoral neck geometry: implications for bone strength. Calcif Tissue Int (1993) 0.92
The combination therapy with alfacalcidol and risedronate improves the mechanical property in lumbar spine by affecting the material properties in an ovariectomized rat model of osteoporosis. BMC Musculoskelet Disord (2009) 0.91
Contributions of aging to the fatigue crack growth resistance of human dentin. Acta Biomater (2012) 0.91
Soy milk and dairy consumption is independently associated with ultrasound attenuation of the heel bone among postmenopausal women: the Adventist Health Study-2. Nutr Res (2011) 0.90
Effect of office-based brief high-impact exercise on bone mineral density in healthy premenopausal women: the Sendai Bone Health Concept Study. J Bone Miner Metab (2010) 0.90
Effects of physical activity, dietary calcium intake and selected lifestyle factors on bone density in young women. CMAJ (1990) 0.90
Integrating pilates exercise into an exercise program for 65+ year-old women to reduce falls. J Sports Sci Med (2011) 0.89
Associations of bone mineral density and lead levels in blood, tibia, and patella in urban-dwelling women. Environ Health Perspect (2008) 0.89
Osteoprotegerin Lys3Asn polymorphism and the risk of fracture in older women. J Clin Endocrinol Metab (2008) 0.88
Risk factors for severity and type of the hip fracture. J Bone Miner Res (2009) 0.87
Age-related changes in proximal humerus bone health in healthy, white males. Osteoporos Int (2012) 0.85
Optimal age of commencing and discontinuing thiazide therapy to protect against fractures. Osteoporos Int (2015) 0.84
Use of renal function measurements for assessing fracture risk in postmenopausal women. Mayo Clin Proc (2008) 0.82
Bone loss. Epidemiology of bone loss. Arthritis Res (2000) 0.82
Role of oestrogen in the development of osteoporosis. Calcif Tissue Int (1991) 0.82
Background for studies on the treatment of male osteoporosis: state of the art. Ann Rheum Dis (2000) 0.80
Extraordinarily low bone mineral density in an old female chimpanzee (Pan troglodytes schweinfurthii) from the Mahale Mountains National Park. Primates (2003) 0.80
Three-dimensional X-ray absorptiometry (3D-XA): a method for reconstruction of human bones using a dual X-ray absorptiometry device. Osteoporos Int (2004) 0.80
The quantitative ADAM questionnaire: a new tool in quantifying the severity of hypogonadism. Int J Impot Res (2009) 0.80
The assembly of the adult skeleton during growth and maturation: implications for senile osteoporosis. J Clin Invest (1999) 0.79
Underestimation of bone loss of the spine with posterior-anterior dual-energy X-ray absorptiometry in patients with spinal cord injury. J Spinal Cord Med (2010) 0.78
Population screening for osteoporosis to prevent fractures. Qual Health Care (1992) 0.78
Different characteristics of cervical and trochanteric hip fractures. Osteoporos Int (1993) 0.78
The effect of bilateral oophorectomy on bone mineral density. Rheumatol Int (2006) 0.78
Deleting Rac1 improves vertebral bone quality and resistance to fracture in a murine ovariectomy model. Osteoporos Int (2010) 0.78
Effect of age on regulation of human osteoclast differentiation. J Cell Biochem (2014) 0.78
Cumulative lead exposure and age at menopause in the Nurses' Health Study cohort. Environ Health Perspect (2014) 0.77
Distribution of vertebral fractures varies among patients according to hip fracture type. Osteoporos Int (2014) 0.77
Cannabinoid receptors as target for treatment of osteoporosis: a tale of two therapies. Curr Neuropharmacol (2010) 0.77
Growth hormone deficiency during puberty reduces adult bone mineral density. Arch Dis Child (1992) 0.77
The Relationship between Radial Bone Properties and Disease Activity and Physical Function in Individuals with Rheumatoid Arthritis. Physiother Can (2012) 0.76
Understanding osteoporosis. West J Med (1991) 0.76
The functional muscle-bone unit in subjects of varying BMD. Osteoporos Int (2013) 0.76
Cut off values of bone mineral density defining postmenopausal women with bone fractures. Ann Rheum Dis (1995) 0.75
The bone mineral density change with aging of Japanese women measured by single energy X-ray absorptiometry and dual energy X-ray absorptiometry. Arch Gynecol Obstet (1993) 0.75
Hip structural changes and fracture risk in osteopenia and osteoporosis. Eurasian J Med (2011) 0.75
Older male physicians have lower risk of trochanteric but not cervical hip fractures. Int J Environ Res Public Health (2015) 0.75
Some determinants of low bone mass and fracture among the elderly. Trans Am Clin Climatol Assoc (1988) 0.75
An overview and management of osteoporosis. Eur J Rheumatol (2016) 0.75
Estrogen replacement therapy for postmenopausal osteoporosis. Can Fam Physician (1986) 0.75
Dorsal vertebral fractures with 'normal' bone mineral density. Ann Rheum Dis (1993) 0.75
Amenorrhoeic athletes: at risk of developing osteoporosis? Br J Sports Med (1984) 0.75
Absence of menopausal effect on hip fracture occurrence in white females. Am J Public Health (1984) 0.75
Bone mass in women with hip fractures. Ann R Coll Surg Engl (1989) 0.75
Effect of trabecular bone loss on cortical strain rate during impact in an in vitro model of avian femur. Biomed Eng Online (2006) 0.75
MEASUREMENT OF BONE MINERAL IN VIVO: AN IMPROVED METHOD. Science (1963) 4.08
Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis. J Clin Invest (1981) 3.60
Clinical significance and pathogenesis of osteoporosis. Br Med J (1971) 2.93
Epidemiology of fractures of the proximal femur in Rochester, Minnesota. Clin Orthop Relat Res (1981) 2.93
Epidemiologic studies of osteoporosis in Women of Puerto Rico and southeastern Michigan with special reference to age, race, national origin and to other related or associated findings. Clin Orthop Relat Res (1966) 1.72
Diagnosis of osteoporosis: usefulness of photon absorptiometry at the radius. J Nucl Med (1977) 1.63
Measurement of bone mineral content in human vertebrae and hip by dual photon absorptiometry. Radiology (1980) 1.42
Spinal mineral loss in oophorectomized women. Determination by quantitative computed tomography. JAMA (1980) 1.40
On the incidence of senile osteoporosis. Ann Intern Med (1960) 1.33
Seasonal variation of histological osteomalacia in femoral-neck fractures. Lancet (1974) 1.17
The diagnosis of osteoporosis. J Bone Miner Res (1994) 10.90
A comparison of sustained-release bupropion and placebo for smoking cessation. N Engl J Med (1997) 9.73
Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. Arch Intern Med (1998) 9.43
Risk of connective-tissue diseases and other disorders after breast implantation. N Engl J Med (1994) 9.25
Hip fractures in the elderly: a world-wide projection. Osteoporos Int (1992) 9.08
Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota. Gastroenterology (1997) 8.51
Involutional osteoporosis. N Engl J Med (1986) 8.20
Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study. Arch Intern Med (2000) 7.62
Psychotropic drug use and the risk of hip fracture. N Engl J Med (1987) 7.53
Updated data on proximal femur bone mineral levels of US adults. Osteoporos Int (1998) 7.14
A motility in the eukaryotic flagellum unrelated to flagellar beating. Proc Natl Acad Sci U S A (1993) 6.50
The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women. Osteoporos Int (2007) 6.44
Risk of new vertebral fracture in the year following a fracture. JAMA (2001) 6.17
The worldwide problem of osteoporosis: insights afforded by epidemiology. Bone (1995) 5.76
Negative feedback defining a circadian clock: autoregulation of the clock gene frequency. Science (1994) 5.76
Prevalence of low femoral bone density in older U.S. adults from NHANES III. J Bone Miner Res (1997) 5.69
Body mass index as a predictor of fracture risk: a meta-analysis. Osteoporos Int (2005) 5.54
Effect of fluoride treatment on the fracture rate in postmenopausal women with osteoporosis. N Engl J Med (1990) 5.49
Birth outcomes in pregnant women taking fluoxetine. N Engl J Med (1996) 5.38
Population-based study of herpes zoster and its sequelae. Medicine (Baltimore) (1982) 5.29
Fracture incidence and association with bone mineral density in elderly men and women: the Rotterdam Study. Bone (2004) 5.27
Purification of tubulin and associated high molecular weight proteins from porcine brain and characterization of microtubule assembly in vitro. Ann N Y Acad Sci (1975) 5.26
A community-based study of the epidemiology of asthma. Incidence rates, 1964-1983. Am Rev Respir Dis (1992) 5.22
Neuropathology of cognitively normal elderly. J Neuropathol Exp Neurol (2003) 5.17
Mortality following inpatient addictions treatment. Role of tobacco use in a community-based cohort. JAMA (1996) 5.17
A prospective, randomized, double-blind, placebo-controlled study of orbital radiotherapy for Graves' ophthalmopathy. Ophthalmology (2001) 5.16
Perspective. How many women have osteoporosis? J Bone Miner Res (1992) 4.99
A meta-analysis of previous fracture and subsequent fracture risk. Bone (2004) 4.92
Prognostic significance of histopathologic subsets in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (1998) 4.88
Dyspepsia and dyspepsia subgroups: a population-based study. Gastroenterology (1992) 4.84
Incidence of clinically diagnosed vertebral fractures: a population-based study in Rochester, Minnesota, 1985-1989. J Bone Miner Res (1992) 4.75
Medical expenditures for the treatment of osteoporotic fractures in the United States in 1995: report from the National Osteoporosis Foundation. J Bone Miner Res (1997) 4.74
Population-based study of survival after osteoporotic fractures. Am J Epidemiol (1993) 4.71
Bronchoscopy in North America: the ACCP survey. Chest (1991) 4.59
Mechanism and fidelity of HIV reverse transcriptase. J Biol Chem (1992) 4.57
Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant. Biochemistry (1991) 4.55
Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli. Biochemistry (1987) 4.29
Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopause. Neurology (2007) 4.28
Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen. J Clin Endocrinol Metab (1998) 4.28
A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Miner Res (1998) 4.24
Treatment of postmenopausal osteoporosis with transdermal estrogen. Ann Intern Med (1992) 4.19
The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population-based cohort: the Rochester Diabetic Neuropathy Study. Neurology (1993) 4.18
Surgical management of Meckel's diverticulum. An epidemiologic, population-based study. Ann Surg (1994) 4.16
Potential effect of authorization bias on medical record research. Mayo Clin Proc (1999) 4.01
Kinetic mechanism of DNA polymerase I (Klenow). Biochemistry (1987) 3.93
Epidemiology of colonic symptoms and the irritable bowel syndrome. Gastroenterology (1991) 3.90
The prevention and treatment of osteoporosis. N Engl J Med (1992) 3.90
An induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kinetics. Biochemistry (1991) 3.86
Effect of the fluoride/calcium regimen on vertebral fracture occurrence in postmenopausal osteoporosis. Comparison with conventional therapy. N Engl J Med (1982) 3.77
Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study. J Clin Endocrinol Metab (2005) 3.67
Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors. Science (1995) 3.60
Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis. J Clin Invest (1981) 3.60
Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer. N Engl J Med (1992) 3.54
Pathway of processive ATP hydrolysis by kinesin. Nature (1995) 3.46
The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption. J Bone Miner Res (2000) 3.38
Mechanism of NO-induced oxidation of myoglobin and hemoglobin. Biochemistry (1996) 3.36
Structural trends in the aging femoral neck and proximal shaft: analysis of the Third National Health and Nutrition Examination Survey dual-energy X-ray absorptiometry data. J Bone Miner Res (2000) 3.36
Thoracic aortic aneurysms: a population-based study. Surgery (1982) 3.36
Assessment of functional gastrointestinal disease: the bowel disease questionnaire. Mayo Clin Proc (1990) 3.34
Exposure to an aeroallergen as a possible precipitating factor in respiratory arrest in young patients with asthma. N Engl J Med (1991) 3.33
Transdermal nicotine for mildly to moderately active ulcerative colitis. A randomized, double-blind, placebo-controlled trial. Ann Intern Med (1997) 3.29
Epidemiology of vertebral fractures in women. Am J Epidemiol (1989) 3.27
The APC gene product in normal and tumor cells. Proc Natl Acad Sci U S A (1993) 3.25
Circadian clock locus frequency: protein encoded by a single open reading frame defines period length and temperature compensation. Proc Natl Acad Sci U S A (1994) 3.23
Kinetic analysis of microtubule self-assembly in vitro. J Mol Biol (1977) 3.15
The Autonomic Symptom Profile: a new instrument to assess autonomic symptoms. Neurology (1999) 3.09
Imaging amyloid deposition in Lewy body diseases. Neurology (2008) 3.09
Smoking and fracture risk: a meta-analysis. Osteoporos Int (2004) 3.08
Incidence of spontaneous pneumothorax in Olmsted County, Minnesota: 1950 to 1974. Am Rev Respir Dis (1979) 3.06
Exercise during growth and bone mineral density and fractures in old age. Lancet (2000) 3.06
Secular trends in the incidence of hip and other osteoporotic fractures. Osteoporos Int (2011) 3.04
Predictors of survival after deep vein thrombosis and pulmonary embolism: a population-based, cohort study. Arch Intern Med (1999) 2.98
Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. J Clin Invest (2000) 2.94
Epidemiology of idiopathic dilated and hypertrophic cardiomyopathy. A population-based study in Olmsted County, Minnesota, 1975-1984. Circulation (1989) 2.94
Quality assessment in hypertension: analysis of process and outcome methods. N Engl J Med (1977) 2.94
Epidemiology of fractures of the proximal femur in Rochester, Minnesota. Clin Orthop Relat Res (1981) 2.93
Risk factors for irritable bowel syndrome: role of analgesics and food sensitivities. Am J Gastroenterol (2000) 2.89
Pneumocystis carinii pneumonia. Differences in lung parasite number and inflammation in patients with and without AIDS. Am Rev Respir Dis (1989) 2.86
A short test of mental status: description and preliminary results. Mayo Clin Proc (1987) 2.85
Fractures after rheumatoid arthritis. A population-based study. Arthritis Rheum (1984) 2.85
Evidence of estrogen receptors in normal human osteoblast-like cells. Science (1988) 2.85
Varying nicotine patch dose and type of smoking cessation counseling. JAMA (1995) 2.82
Epidemiologic features of humeral fractures. Clin Orthop Relat Res (1982) 2.79