Published in Biochem Pharmacol on May 15, 1981
Active transport of gamma-aminobutyric acid and glycine into synaptic vesicles. Proc Natl Acad Sci U S A (1989) 1.01
Diacetoxypiperidinium analogs of acetylcholine. J Med Chem (1973) 1.41
Direct measurement of glutamate release in the brain using a dual enzyme-based electrochemical sensor. Brain Res (1994) 1.32
Cloning of cDNA for the glutamate-binding subunit of an NMDA receptor complex. Nature (1991) 1.20
Thymidylate synthetase as target enzyme for the inhibitory activity of 5-substituted 2'-deoxyuridines on mouse leukemia L1210 cell growth. Mol Pharmacol (1981) 1.07
High affinity Ca2+-stimulated Mg2+-dependent ATPase in rat brain synaptosomes, synaptic membranes, and microsomes. J Biol Chem (1983) 1.01
Adenosine modulation of synaptosomal dopamine release. Life Sci (1979) 1.01
Developmental expression, compartmentalization, and possible role in excitotoxicity of a putative NMDA receptor protein in cultured hippocampal neurons. Brain Res (1991) 1.00
Basic FGF regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in hippocampal neurons. J Neurosci (1993) 0.99
Sequence analysis of bovine lens aldose reductase. J Biol Chem (1990) 0.97
Immune labeling and purification of a 71-kDa glutamate-binding protein from brain synaptic membranes. Possible relationship of this protein to physiologic glutamate receptors. J Biol Chem (1988) 0.93
Role of thymidine kinase in the inhibitory activity of 5-substituted-2'-deoxyuridines on the growth of human and murine tumor cell lines. Biochem Pharmacol (1982) 0.92
Alcohol and local anesthetic effects on Na+-dependent Ca2+ fluxes in brain synaptic membrane vesicles. Biochem Pharmacol (1983) 0.91
Effects of chronic ethanol treatment on the expression of calcium transport carriers and NMDA/glutamate receptor proteins in brain synaptic membranes. J Neurochem (1997) 0.90
Antiviral activity of 5-methylthiomethyl-2'-deoxyuridine and other 5-substituted 2'-deoxyuridines. Biochem Pharmacol (1979) 0.89
Synthesis of carbonate analogs of dinucleosides. 3'-Thymidinyl 5'-thymidinyl carbonate, 3'-thymidinyl 5'-(5-fluoro-2'-deoxyuridinyl) carbonate, and 3'-(5-fluoro-2'-deoxyuridinyl) 5'-thymidinyl carbonate. J Med Chem (1969) 0.88
Mechanims of stimulation of in vitro protein synthesis by some copolymers of styrene, vinyluracil, and vinyladenine with maleic acid and acrylic acid. Biochemistry (1976) 0.86
Localization of a gene for a glutamate binding subunit of a NMDA receptor (GRINA) to 8q24. Genomics (1996) 0.85
Developmental expression of N-methyl-D-aspartate (NMDA)-induced neurotoxicity, NMDA receptor function, and the NMDAR1 and glutamate-binding protein subunits in cerebellar granule cells in primary cultures. Neurochem Res (1995) 0.83
Purification and molecular characterization of the brain synaptic membrane glutamate-binding protein. J Neurochem (1983) 0.82
Oxime and dithiolane derivatives of 5-formyl-2'-deoxyuridine and their 5'-phosphates: antiviral effects and thymidylate synthetase inhibition. J Med Chem (1980) 0.82
Partial purification and characterization of a glutamate-binding membrane glycoprotein from rat brain. Biochem Biophys Res Commun (1975) 0.82
Synthesis of the alpha and beta anomers of 1-(2-deoxy-D-ribofuranosyl)-4-pyridone. J Med Chem (1974) 0.82
5-Substituted 2'-deoxyuridines: correlation between inhibition of tumor cell growth and inhibition of thymidine kinase and thymidylate synthetase. Biochem Pharmacol (1982) 0.82
Polynucleotide analogs: acrylic acid and maleic acid copolymers of 1-vinyluracil and 9-vinyladenine. Biochemistry (1975) 0.82
Calcium influx through NMDA receptors, chronic receptor inhibition by ethanol and 2-amino-5-phosponopentanoic acid, and receptor protein expression. J Neurochem (1999) 0.81
Characteristics of Mg2+-dependent, ATP-activated Ca2+ transport in synaptic and microsomal membranes and in permeabilized synaptosomes. J Biol Chem (1987) 0.81
Thiol addition to quinones: model reactions for the inactivation of thymidylate synthase by 5-p-benzoquinonyl-2'-deoxyuridine 5'-phosphate. J Med Chem (1986) 0.80
Hydrodynamic properties of the purified glutamate-binding protein subunit of the N-methyl-D-aspartate receptor. J Biol Chem (1991) 0.80
Synthesis of 5-substituted uracil derivatives. J Med Chem (1976) 0.80
Chronic ethanol exposure increases gene transcription of subunits of an N-methyl-D-aspartate receptor-like complex in cortical neurons in culture. Neurosci Lett (2001) 0.80
Approaches to the Synthesis of 1-Deazauridine and 2'-Deoxy-1-deazauridine. J Med Chem (1967) 0.80
Fluorogenic tagging of protein 3-nitrotyrosine with 4-(aminomethyl)benzene sulfonate in tissues: a useful alternative to Immunohistochemistry for fluorescence microscopy imaging of protein nitration. Free Radic Biol Med (2012) 0.80
Synthesis of 5-substituted 2'-deoxyuridines. J Med Chem (1976) 0.79
Immunocytochemical and in situ hybridization studies of the expression and distribution of three subunits of a complex with N-methyl-D-aspartate receptor-like properties. Neuroscience (1999) 0.79
Molecular characteristics of glutamate receptors in the mammalian brain. Mol Cell Biochem (1981) 0.79
A synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein: isolation and immunochemical characterization. Neurochem Int (1996) 0.79
Ethanol effects on synaptic glutamate receptor function and on membrane lipid organization. Pharmacol Biochem Behav (1983) 0.79
Purification, biochemical characterization, binding activity, and selectivity of a glutamate binding protein from bovine brain. J Neurochem (1984) 0.79
Antibacterial activity of nitrobenzofurans. J Med Chem (1970) 0.79
Activity-dependent nitric oxide concentration dynamics in the laterodorsal tegmental nucleus in vitro. J Neurophysiol (2001) 0.79
High-affinity glutamic acid binding to brain synaptic membranes. Biochim Biophys Acta (1974) 0.78
The glutamate receptor-like protein of brain synaptic membranes is a metalloprotein. Biochem Biophys Res Commun (1979) 0.78
L-Glutamate effects on electrical potentials of synaptic plasma membrane vesicles. Biochim Biophys Acta (1982) 0.78
Solubilization, partial purification, and reconstitution of glutamate- and N-methyl-D-aspartate-activated cation channels from brain synaptic membranes. Biochemistry (1991) 0.78
Synthesis of 5-[(methylthio)methyl]-2'-deoxyuridine, the corresponding sulfoxide and sulfone, and their 5'-phosphates: antiviral effects and thymidylate synthetase inhibition. J Med Chem (1980) 0.78
Ion channel sensors for glutamic acid. Anal Chem (1991) 0.78
Protein half-lives of calmodulin and the plasma membrane Ca-ATPase in rat brain. Biochem Biophys Res Commun (1997) 0.78
Ion channel properties of a protein complex with characteristics of a glutamate/N-methyl-D-aspartate receptor. FEBS Lett (1996) 0.78
Ca++ fluxes in resealed synaptic plasma membrane vesicles. Life Sci (1981) 0.78
Effects of acute and chronic ethanol intake on synaptosomal glutamate binding activity. Biochem Pharmacol (1978) 0.78
Immunochemical characterization of brain synaptic membrane glutamate-binding proteins. J Biol Chem (1990) 0.78
Immunochemical and immunohistochemical characterization of a synaptic membrane protein that binds the competitive antagonists of NMDA receptors. Neurosci Lett (1993) 0.78
Effects of L-glutamic acid on synaptosomal and synaptic membrane Na+ fluxes and (Na+-K+)-ATPase. J Biol Chem (1980) 0.78
Cloning of the cDNA for a brain glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein. Biochem Biophys Res Commun (1995) 0.77
Superoxide modification and inactivation of a neuronal receptor-like complex. Free Radic Biol Med (2002) 0.77
Isolation of glutamate-binding proteins from rat and bovine brain synaptic membranes and immunochemical and immunocytochemical characterization. Neuroscience (1992) 0.77
Solubilization and partial purification of 3-((+-)-2-carboxypiperazine-4-yl)-[1,2-3H]propyl-1-phosphonic acid recognition proteins from rat brain synaptic membranes. J Biol Chem (1990) 0.77
5-[(4-Methyl-1,2,3,4-tetrahydroquinoxalyl)methyl]-2'-deoxyuridine 5'-phosphate: an analogue of a proposed intermediate in thymidylate synthetase catalysis. J Med Chem (1979) 0.77
Calcium binding to brain synaptosomes. Effects of chronic ethanol intake. Biochem Pharmacol (1979) 0.77
Cloning of a brain N-methyl-D-aspartate- and D, L-epsilon-2-amino-4-propyl-5-phosphono-3-pentanoic acid (CGP 39653)-binding protein. Biochem Biophys Res Commun (1998) 0.77
The 71 kDa glutamate-binding protein is increased in cerebellar granule cells after chronic ethanol treatment. Brain Res Mol Brain Res (1996) 0.76
A chemical model for thymidylate synthetase catalysis. Biochemistry (1973) 0.76
L-glutamate stimulation of Na+ efflux from brain synaptic membrane vesicles. J Biol Chem (1981) 0.76
Purification and pharmacological and immunochemical characterization of synaptic membrane proteins with ligand-binding properties of N-methyl-D-aspartate receptors. J Biol Chem (1994) 0.76
Protein half-lives of two subunits of an NMDA receptor-like complex, the 71-kDa glutamate-binding and the 80-kDa CPP-binding protein. Biochem Biophys Res Commun (1997) 0.75
Glutamic acid and ethanol dependence. Pharmacol Biochem Behav (1978) 0.75
Spider venoms inhibit L-glutamate binding to brain synaptic membrane receptors. Proc Natl Acad Sci U S A (1984) 0.75
Inactivation of thymidylate synthase at an alternate high-affinity binding site. J Med Chem (1987) 0.75
Antiviral, antitumor, and thymidylate synthetase inhibition studies of 5-substituted styryl derivatives of 2'-deoxyuridine and their 5'-phosphates. Biochem Pharmacol (1981) 0.75
5-p-benzoquinonyl-2'-deoxyuridine 5'-phosphate: a possible mechanism-based inhibitor of thymidylate synthetase. J Med Chem (1983) 0.75
Structure of the product from a novel cyclization reaction involving a C(6)-substituted uridine analog. Acta Crystallogr C (1993) 0.75
Pericillinase inhibition. J Med Chem (1973) 0.75
Cofactor inhibitors of thymidylate synthetase. Piperidine and tetrahydroquinoline analogs of tetrahydrofolic acid. J Med Chem (1970) 0.75
Synthesis and pharmacological activity of dihydrobenzofurans. J Med Chem (1971) 0.75
Omega-dithiolano amino acids. J Med Chem (1969) 0.75
Cofactor inhibition of thymidylate synthetase. Tetrahydrofolic acid analogs. J Med Chem (1970) 0.75
5-Cyano-2'-deoxyuridine 5'-phosphate: a potent competitive inhibitor of thymidylate synthetase. J Med Chem (1979) 0.75
Synthesis of gamma-dimethylaminomethyl-alpha-phenylcycloalkyl propionates as potential analgetics. J Med Chem (1970) 0.75
Synthetic inhibitors of Escherichia coli, calf thymus, and Ehrlich ascites tumor thymidylate synthetase. J Med Chem (1976) 0.75
5(E)-(3-azidostyryl)-2'-deoxyuridine 5'-phosphate is a photoactivated inhibitor of thymidylate synthetase. Biochem Biophys Res Commun (1980) 0.75
Polynucleotide analogues. Copolymers of vinyl bases with acrylic acid, methylacrylic acid, acrylamide, and 1-vinylpyrrolidone. J Med Chem (1977) 0.75
Bisquaternary ammonium indolines and perhydroindoles in ganglionic blockade. J Med Chem (1968) 0.75
Letter: 5-iodoacetamidomethyl-2'-deoxyuridine 5'-phosphate. A selective inhibitor of mammalian thymidylate synthetases. J Am Chem Soc (1976) 0.75
The synthesis of the alpha and beta anomers of 1-(2-deoxy-D-ribofuranosyl)-2-pyridone. J Med Chem (1970) 0.75
Palladium (II)-catalyzed olefin-coupling reactions of kainic acid: effects of substitution on the isopropenyl group on receptor binding. J Med Chem (1984) 0.75
5 (alpha-bromoacetyl)-2'=deoxyuridine 5'-phosphate: a mechanism based affinity label for thymidylate synthetase. Biochem Biophys Res Commun (1979) 0.75
N-thymidylglycine and ethyl p-N-thymidylaminobenzoate. J Med Chem (1967) 0.75
Enzyme affinity of the 5,6-dihydro derivatives of the substrate and product of thymidylate synthetase catalysis. J Med Chem (1979) 0.75
Linear free energy relationship studies of enzyme active site binding: thymidylate synthase. J Med Chem (1988) 0.75
Registered nurses' perceptions of liberal education. J Nurs Educ (1993) 0.75
Concanavalin A binding to brain particulate preparations and its effect on adenylate cyclase. Life Sci (1976) 0.75
5-Nitro-2'-deoxyuridine 5'-monophosphate is a potent irreversible inhibitor of Lactobacillus caesi thymidylate synthetase. Biochem Biophys Res Commun (1978) 0.75
Charge-spatial models: cis- and trans-3- and -4-Substituted cyclohexyl phosphates as analogs of 2'-deoxyuridine 5'-phosphate. J Med Chem (1969) 0.75
5-Quinone derivatives of 2'-deoxyuridine 5'-phosphate: inhibition and inactivation of thymidylate synthase, antitumor cell, and antiviral studies. J Med Chem (1987) 0.75
5-(alpha-Bromoacetyl)-2'-deoxyuridine 5'-phosphate: an affinity label for thymidylate synthetase. J Med Chem (1979) 0.75
Thymidylate synthetase inhibitors. Synthesis of N-substituted 5-aminomethyl-2'-deoxyuridine 5'-phosphates. J Med Chem (1977) 0.75
The conformational preferences of sulfur and oxygen in hemithioketals. J Phys Chem (1969) 0.75
Charge-spatial models. 2. cis-and trans-3-and-4-carboxycyclohexyl phosphates and the carboxylate esters as analogs of 2'-deoxyuridine 5'-phosphate. J Med Chem (1971) 0.75
Synthesis of gamma-dimethylamino-alpha-phenylcycloalkyl propionates as potential analgetics. J Med Chem (1970) 0.75