Published in Clin Chem on August 01, 1981
Transplantation of multiple abdominal viscera. JAMA (1989) 3.59
Biliary Excretion of Cyclosporine in Liver Transplant Patients. Transplant Proc (1985) 1.98
Orthotopic liver transplantation in children: two-year experience with 47 patients. Pediatrics (1984) 1.86
EFFECT OF CYCLOSPORIN ON HEPATIC REGENERATION. Surg Forum (1986) 1.59
Cyclosporine Monitoring and Pharmacokinetics in Pediatrie Liver Transplant Patients. Transplant Proc (1985) 1.55
Linear growth following pediatric liver transplantation. Am J Dis Child (1987) 1.33
Human polymorphonuclear leukocyte interaction with cyclosporine A. Infect Immun (1984) 1.27
Excretion of cyclosporine and its metabolites in human bile. Transplant Proc (1986) 1.27
A single institution, randomized, prospective trial of cyclosporin versus azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients. Ann Surg (1985) 1.15
Cyclosporine absorption following orthotopic liver transplantation. J Clin Pharmacol (1987) 1.07
Effect of bile on cyclosporine absorption in dogs. Res Commun Chem Pathol Pharmacol (1986) 0.93
Cyclosporine metabolism and pharmacokinetics following intravenous and oral administration in the dog. Transplantation (1986) 0.93
Cyclosporine G Analysis and Monitoring by High-Pressure Liquid Chromatography. Transplant Proc (1986) 0.91
Changes in life-style after liver transplantation. Pediatrics (1988) 0.91
Ulcerative colitis disease activity following treatment of associated primary sclerosing cholangitis with cyclosporin. Gut (1993) 0.90
Determination of cyclosporine concentration in bile. Transplantation (1986) 0.87
Calcium channel antagonists and cyclosporine metabolism: in vitro studies with human liver microsomes. Br J Clin Pharmacol (1989) 0.87
Cyclosporine pharmacokinetic profiles in liver, heart, and kidney transplant patients as determined by high-performance liquid chromatography. Transplant Proc (1986) 0.82
The outcome of 304 primary renal transplants in children (1968-1985). Ann Surg (1986) 0.81
Extraction ratio of cyclosporine in a liver transplant patient with organ rejection. J Pharm Sci (1985) 0.81
Hepatic Homograft Survival in Pediatric Orthotopic Liver Transplantation with Cyclosporine and Steroids. Transplant Proc (1983) 0.78
The influence of liver dysfunction on cyclosporine pharmacokinetics--a comparison between 70 per cent hepatectomy and complete bile duct ligation in dogs. Jpn J Surg (1989) 0.76
Cyclosporine measurement by FPIA, PC-RIA, and HPLC following liver transplantation. Transplant Proc (1990) 0.76
Diurnal variation in cyclosporine kinetics. Ther Drug Monit (1986) 0.75
Liquid-chromatographic determination of cyclosporin A in blood and plasma. Clin Chem (2008) 0.75
The clearance of cyclosporine by hemodialysis. J Clin Pharmacol (1985) 0.75
Kinetic model for gentamicin dosing with the use of individual patient parameters. Clin Pharmacol Ther (1977) 3.05
Pharmacokinetics of dosing regimens which utilize multiple intravenous infusions: gentamicin in burn patients. J Pharmacokinet Biopharm (1976) 2.59
Massive theophylline overdose. Rapid elimination by charcoal hemoperfusion. JAMA (1978) 1.97
Pharmacokinetics of vancomycin: observations in 28 patients and dosage recommendations. Antimicrob Agents Chemother (1982) 1.97
Application of microdialysis in pharmacokinetic studies. Pharm Res (1997) 1.74
Increased dosage requirements of gentamicin in burn patients. J Trauma (1976) 1.23
The necessity of increased doses of amikacin in burn patients. Surgery (1978) 1.18
Microdialysis calibration using retrodialysis and zero-net flux: application to a study of the distribution of zidovudine to rabbit cerebrospinal fluid and thalamus. Pharm Res (1993) 1.18
Severe methanol poisoning. Application of a pharmacokinetic model for ethanol therapy and hemodialysis. Am J Med (1979) 1.13
Liquid-chromatographic method for simultaneous determination of phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in plasma and urine. Clin Chem (1980) 1.12
Pharmacokinetics of meropenem determined by microdialysis in the peritoneal fluid of patients with severe peritonitis associated with septic shock. Clin Pharmacol Ther (2007) 1.09
Effect of probenecid on the renal and nonrenal clearances of zidovudine and its distribution into cerebrospinal fluid in the rabbit. J Pharm Sci (1989) 0.98
Distributional transport kinetics of zidovudine between plasma and brain extracellular fluid/cerebrospinal fluid in the rabbit: investigation of the inhibitory effect of probenecid utilizing microdialysis. J Pharmacol Exp Ther (1993) 0.98
Bioequivalence of carbamazepine chewable and conventional tablets: single-dose and steady-state studies. J Pharm Sci (1985) 0.90
Competitive inhibition of zidovudine clearance by probenecid during continuous coadministration. Pharm Res (1992) 0.88
Microdialysis studies of the middle ear distribution kinetics of amoxicillin in the awake chinchilla. J Pharm Sci (2001) 0.87
Phenytoin metabolism in pregnancy. Obstet Gynecol (1980) 0.87
Plasma and lymph pharmacokinetics of recombinant human interleukin-2 and polyethylene glycol-modified interleukin-2 in pigs. J Pharmacol Exp Ther (2000) 0.85
Microdialysis studies of the distribution of stavudine into the central nervous system in the freely-moving rat. Pharm Res (1997) 0.85
Zidovudine transport in the rabbit brain during intravenous and intracerebroventricular infusion. J Pharm Sci (1995) 0.85
High-performance liquid chromatographic determination of 2',3'-didehydro-3'-deoxythymidine (d4T) in human and rabbit plasma and urine and its application to pharmacokinetic studies in the rabbit. Pharm Res (1991) 0.84
Analysis of zidovudine distribution to specific regions in rabbit brain using microdialysis. Pharm Res (1992) 0.83
Probenecid inhibits the metabolic and renal clearances of zidovudine (AZT) in human volunteers. Pharm Res (1990) 0.83
Pharmacokinetics and metabolism of diclofenac sodium in Yucatan miniature pigs. Pharm Res (1994) 0.83
A sensitive liquid-chromatographic method for determination of 3'-azido-3'-deoxythymidine (AZT) in plasma and urine. Clin Chem (1988) 0.83
The pharmacokinetics of cyclosporine. I. Single dose and constant rate infusion studies in the rabbit. Drug Metab Dispos (1985) 0.83
Simultaneous first- and zero-order absorption of carbamazepine tablets in humans. J Pharm Sci (1986) 0.82
Pharmacokinetics of propylene glycol in humans during multiple dosing regimens. J Pharm Sci (1985) 0.81
A sensitive and specific liquid-chromatographic assay for determination of ganciclovir in plasma and urine and its application to pharmacokinetic studies in the rabbit. Pharm Res (1990) 0.81
Drug kinetics in burn patients. Clin Pharmacokinet (1981) 0.80
The relationship between urine and plasma concentrations of carbamazepine: implications for therapeutic drug monitoring. Pharm Res (1991) 0.78
Simultaneous liquid-chromatographic determination of carbamazepine and its epoxide metabolite in plasma. Clin Chem (1982) 0.78
American ginseng. III. Pharmacokinetics of ginsenosides in the rabbit. Eur J Drug Metab Pharmacokinet (1980) 0.78
Absorption of cyclosporine from rabbit small intestine in situ. J Pharm Sci (1986) 0.78
Zidovudine transport within the rabbit brain during intracerebroventricular administration and the effect of probenecid. J Pharm Sci (1997) 0.78
Improved liquid-chromatographic determination of cyclosporine and its metabolites in blood. Clin Chem (1988) 0.78
The pharmacokinetics of cyclosporine. II. Blood plasma distribution and binding studies. Drug Metab Dispos (1985) 0.78
Transaqueous diffusion of acetylcholine to denervated iris sphincter muscle: a mechanism for the tonic pupil syndrome (Adie syndrome). Ann Neurol (1978) 0.78
Transient steady-state analysis: application in the determination of the relative formation and elimination clearances of two major carbamazepine metabolites in humans. Pharm Res (1993) 0.77
Subcutaneous absorption of cyclosporine in rabbits. Transplant Proc (1988) 0.77
Effect of influenza vaccination on plasma phenytoin concentrations. Ther Drug Monit (1979) 0.77
High-performance liquid chromatographic analysis of (S)-alpha-amino-5-phosphonomethyl[1,1'-biphenyl]-3-propanoic acid (EAB 515) in brain and blood microdialysate (on-line) and in plasma ultrafiltrate of freely moving rats. J Chromatogr B Biomed Appl (1996) 0.77
Increased clearance of phenytoin during infectious mononucleosis. N Engl J Med (1979) 0.77
Safety and pharmacokinetic study with escalating doses of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy male volunteers. Clin Invest Med (2000) 0.77
Investigation of the distribution of EAB 515 to cortical ECF and CSF in freely moving rats utilizing microdialysis. Pharm Res (1994) 0.77
Kinetics of subcellular distribution of compounds in simple biosystems and its use in QSAR. J Theor Biol (1997) 0.77
Pharmacokinetic model for subcutaneous absorption of cyclosporine in the rabbit during chronic treatment. J Pharm Sci (1992) 0.77
Effect of polyethylene glycol 400 on the intestinal permeability of carbamazepine in the rabbit. Pharm Res (1991) 0.77
Bioavailability and pharmacokinetics of intravenously and orally administered allopurinol in healthy beagles. Am J Vet Res (1997) 0.77
In vitro-in vivo correlation and dissolution studies with oral theophylline dosage forms. J Pharm Sci (1985) 0.77
Transsynovial drug distribution: synovial mean transit time of diclofenac and other nonsteroidal antiinflammatory drugs. Pharm Res (1994) 0.76
Absorptive clearance of carbamazepine and selected metabolites in rabbit intestine. Pharm Res (1991) 0.76
The distribution of propranolol between blood and plasma in hypertensive patients. Br J Clin Pharmacol (1974) 0.75
Protein binding of phenytoin, p-hydroxy phenytoin, and p-hydroxy phenytoin glucuronide. J Clin Pharmacol (1987) 0.75
Gas-liquid chromatographic determination of propylene glycol in plasma and urine. Clin Chem (1983) 0.75
Simultaneous determination of carbamazepine and its epoxide and transdiol metabolites in plasma by microbore liquid chromatography. Clin Chem (1988) 0.75
Thiamphenicol pharmacokinetics in sheep. J Vet Pharmacol Ther (1994) 0.75
Pharmacokinetics of valproic acid in children: I. Multiple antiepileptic drug therapy. Neurology (1983) 0.75
Determination of the relative formation and elimination clearance of two major carbamazepine metabolites in humans: a comparison between traditional and pooled sample analysis. Pharm Res (1991) 0.75
Steady-state plasma concentrations as a function of the absorption rate and dosing interval for drugs exhibiting concentration-dependent clearance: consequences for phenytoin therapy. J Pharmacokinet Biopharm (1979) 0.75
Contribution of 5-(4-hydroxyphenyl)-5-phenylhydantoin to the discrepancy between phenytoin analyses by EMIT and high-pressure liquid chromatography. Ther Drug Monit (1984) 0.75
Modeling the route of administration-based enhancement in the brain delivery of EAB 515, studied by microdialysis. J Drug Target (1997) 0.75
Thiamphenicol pharmacokinetics in beef and dairy cattle. J Vet Pharmacol Ther (1994) 0.75
Elevated serum phenytoin concentrations in a uremic patient when measured by enzyme-multiplied immunoassay. Drug Intell Clin Pharm (1981) 0.75
Altered phenytoin clearance with febrile illness. Neurology (1986) 0.75
Rapid and slow release phenytoin in epileptic patients at steady state: assessment of relative bioavailability utilizing Michaelis-Menten parameters. J Pharmacokinet Biopharm (1982) 0.75
The estimation of the plasma free fraction of cyclosporine in rabbits and heart transplant patients: the application of a physiological model of renal clearance. Biopharm Drug Dispos (1995) 0.75
Concentration-time profile of phenytoin after admixture with small volumes of intravenous fluids. Am J Hosp Pharm (1978) 0.75
A partial area difference analysis for estimating elimination rate constants and distribution volumes of metabolites. J Pharm Sci (1998) 0.75
Effect of co-administration of Intralipid on the pharmacokinetics of cyclosporine in the rabbit. Biopharm Drug Dispos (1991) 0.75
Theophylline absorption and disposition in rabbits: oral, intravenous, and concentration-dependent kinetic studies. J Pharm Sci (1981) 0.75
Rate studies on the binding of bilirubin by ion-exchange resins. J Pharm Sci (1968) 0.75
Variable first-pass elimination of propranolol following single and multiple oral doses in hypertensive patients. Eur J Drug Metab Pharmacokinet (1982) 0.75
Pharmacokinetics of propylene glycol in the rabbit. J Pharmacokinet Biopharm (1987) 0.75
Analysis of diclofenac and four of its metabolites in human urine by HPLC. Pharm Res (1995) 0.75
Acute phenytoin and primidone intoxication: a pharmacokinetic analysis. J Clin Pharmacol (1981) 0.75
Rapid and slow release phenytoin in epileptic patients at steady state: comparative plasma levels and toxicity. J Pharmacokinet Biopharm (1982) 0.75
Coefficient of variation as measure of compliance. Lancet (1978) 0.75