Published in Pflugers Arch on November 01, 1981
A comprehensive guide to the ROMK potassium channel: form and function in health and disease. Am J Physiol Renal Physiol (2009) 2.51
Stimulus-secretion coupling: cytoplasmic calcium signals and the control of ion channels in exocrine acinar cells. J Physiol (1992) 2.31
Molecular physiology of cation-coupled Cl- cotransport: the SLC12 family. Pflugers Arch (2003) 1.69
Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice. J Biol Chem (2002) 1.49
Mediators of the secretory response to kinins. Br J Pharmacol (1984) 1.49
Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidney. Proc Natl Acad Sci U S A (1994) 1.41
Hormone-induced co-transport with specific pharmacological properties in erythrocytes of rainbow trout, Salmo gairdneri. J Physiol (1984) 1.27
A new endogenous natriuretic factor: LLU-alpha. Proc Natl Acad Sci U S A (1996) 1.25
Cation-coupled chloride influx in squid axon. Role of potassium and stoichiometry of the transport process. J Gen Physiol (1983) 1.23
Chloride/formate exchange with formic acid recycling: a mechanism of active chloride transport across epithelial membranes. Proc Natl Acad Sci U S A (1985) 1.20
Effects of vasopressin and bradykinin on anion transport by the rat cortical collecting duct. Evidence for an electroneutral sodium chloride transport pathway. J Clin Invest (1986) 1.19
Sodium chloride absorption by the urinary bladder of the winter flounder. A thiazide-sensitive, electrically neutral transport system. J Clin Invest (1984) 1.17
Consequences of potassium recycling in the renal medulla. Effects of ion transport by the medullary thick ascending limb of Henle's loop. J Clin Invest (1982) 1.15
Thick ascending limb: the Na(+):K (+):2Cl (-) co-transporter, NKCC2, and the calcium-sensing receptor, CaSR. Pflugers Arch (2008) 1.12
Interactions among prostaglandin E2, antidiuretic hormone, and cyclic adenosine monophosphate in modulating Cl- absorption in single mouse medullary thick ascending limbs of Henle. J Clin Invest (1983) 1.04
Prenatal programming of rat thick ascending limb chloride transport by low-protein diet and dexamethasone. Am J Physiol Regul Integr Comp Physiol (2009) 1.03
Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts. Am J Physiol Cell Physiol (2013) 1.01
Hypertension resistance polymorphisms in ROMK (Kir1.1) alter channel function by different mechanisms. Am J Physiol Renal Physiol (2010) 0.98
Physiology and pathophysiology of SLC12A1/2 transporters. Pflugers Arch (2013) 0.96
Novel diuretic targets. Am J Physiol Renal Physiol (2013) 0.93
Molecular aspects of structure, gating, and physiology of pH-sensitive background K2P and Kir K+-transport channels. Physiol Rev (2015) 0.92
In vivo evidence of impaired solute transport by the thick ascending limb in potassium-depleted rats. J Clin Invest (1984) 0.90
Furosemide-sensitive Na and K fluxes in human red cells. Net uphill Na extrusion and equilibrium properties. J Gen Physiol (1986) 0.88
Effect of acidosis on chloride transport in the cortical thick ascending limb of Henle perfused in vitro. J Clin Invest (1986) 0.88
Energetics of chloride secretion in canine tracheal epithelium. Comparison of the metabolic cost of chloride transport with the metabolic cost of sodium transport. J Clin Invest (1984) 0.88
Chloride transport in the mammalian proximal tubule. Pflugers Arch (1986) 0.88
Physiology and pathophysiology of ClC-K/barttin channels. Front Physiol (2010) 0.87
Passive potassium transport in LK sheep red cells. Modification by N-ethyl maleimide. J Gen Physiol (1983) 0.87
Computational and functional analyses of a small-molecule binding site in ROMK. Biophys J (2015) 0.87
Oxygen consumption and active sodium and chloride transport in bovine tracheal epithelium. J Physiol (1986) 0.85
Thick ascending limb of the loop of Henle. Clin J Am Soc Nephrol (2014) 0.85
Acetylcholine-evoked potassium release in the mouse pancreas. J Physiol (1985) 0.84
The use of membrane vesicles to study the NaCl/KCl cotransporter involved in active transepithelial chloride transport. Pflugers Arch (1985) 0.84
Perfusion of isolated tubules of the shark rectal gland. Electrical characteristics and response to hormones. J Clin Invest (1983) 0.84
A brief history of the study of fish osmoregulation: the central role of the Mt. Desert Island Biological Laboratory. Front Physiol (2010) 0.80
Sodium reabsorption in thick ascending limb of Henle's loop: effect of potassium channel blockade in vivo. Br J Pharmacol (2000) 0.80
Effects of NKCC2 isoform regulation on NaCl transport in thick ascending limb and macula densa: a modeling study. Am J Physiol Renal Physiol (2014) 0.79
Stimulation of Ca2+-sensing receptor inhibits the basolateral 50-pS K channels in the thick ascending limb of rat kidney. Biochim Biophys Acta (2011) 0.78
Ion-selective micro-electrode studies of the electrochemical potentials in trout urinary bladder. J Physiol (1986) 0.77
Renal Tubular Ubiquitin-Protein Ligase NEDD4-2 Is Required for Renal Adaptation during Long-Term Potassium Depletion. J Am Soc Nephrol (2017) 0.77
Diuretic action of potassium channel blockers. Eur J Clin Pharmacol (1993) 0.75
Sodium and chloride co-transport by preimplantation rabbit blastocysts. J Physiol (1983) 0.75
Na+-K+-Cl- cotransporter (NKCC) maintains the chloride gradient to sustain pacemaker activity in interstitial cells of Cajal. Am J Physiol Gastrointest Liver Physiol (2016) 0.75
AVP dynamically increases paracellular Na(+) permeability and transcellular NaCl transport in the medullary thick ascending limb of Henle's loop. Pflugers Arch (2016) 0.75
A constitutively open potassium channel formed by KCNQ1 and KCNE3. Nature (2000) 3.75
Ion transport mechanisms in thick ascending limb of Henle's loop of mammalian nephron. Physiol Rev (1985) 2.94
Cl(-)-channel blockers in the thick ascending limb of the loop of Henle. Structure activity relationship. Pflugers Arch (1986) 2.04
Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism. Proc Natl Acad Sci U S A (1998) 1.90
Role of K(V)LQT1 in cyclic adenosine monophosphate-mediated Cl(-) secretion in human airway epithelia. Am J Respir Cell Mol Biol (2000) 1.85
Chemical probes for anion transporters of mammalian cell membranes. Am J Physiol (1992) 1.85
Properties of the luminal membrane of isolated perfused rat pancreatic ducts. Effect of cyclic AMP and blockers of chloride transport. Pflugers Arch (1988) 1.57
Cholinergic ion secretion in human colon requires coactivation by cAMP. Am J Physiol (1998) 1.48
The amiloride-inhibitable Na+ conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways. J Clin Invest (1998) 1.42
Molecular and functional characterization of the small Ca(2+)-regulated K+ channel (rSK4) of colonic crypts. Pflugers Arch (1999) 1.38
Evidence for a bicarbonate leak in the proximal tubule of the rat kidney. Pflugers Arch (1980) 1.36
Cation selectivity of the isolated perfused cortical thick ascending limb of Henle's loop of rabbit kidney. Pflugers Arch (1981) 1.35
The luminal K+ channel of the thick ascending limb of Henle's loop. Pflugers Arch (1990) 1.34
Angiotensin II depolarizes podocytes in the intact glomerulus of the Rat. J Clin Invest (1997) 1.30
Cl- transport by cystic fibrosis transmembrane conductance regulator (CFTR) contributes to the inhibition of epithelial Na+ channels (ENaCs) in Xenopus oocytes co-expressing CFTR and ENaC. J Physiol (1998) 1.28
Properties of the basolateral membrane of the cortical thick ascending limb of Henle's loop of rabbit kidney. A model for secondary active chloride transport. Pflugers Arch (1983) 1.26
Wild type but not deltaF508 CFTR inhibits Na+ conductance when coexpressed in Xenopus oocytes. FEBS Lett (1996) 1.24
Inhibition of IKs in guinea pig cardiac myocytes and guinea pig IsK channels by the chromanol 293B. Pflugers Arch (1996) 1.24
Macula densa cells sense luminal NaCl concentration via furosemide sensitive Na+2Cl-K+ cotransport. Pflugers Arch (1989) 1.22
A simplified method for isolation of large numbers of defined nephron segments. Am J Physiol (1997) 1.20
Simultaneous measurements of cytosolic and mitochondrial Ca2+ transients in HT29 cells. J Biol Chem (1998) 1.18
The first-nucleotide binding domain of the cystic-fibrosis transmembrane conductance regulator is important for inhibition of the epithelial Na+ channel. Proc Natl Acad Sci U S A (1999) 1.17
Diphenylamine-2-carboxylate, a blocker of the Cl(-)-conductive pathway in Cl(-)-transporting epithelia. Pflugers Arch (1985) 1.16
Electrophysiological study of transport systems in isolated perfused pancreatic ducts: properties of the basolateral membrane. Pflugers Arch (1988) 1.16
The role of the IsK protein in the specific pharmacological properties of the IKs channel complex. Br J Pharmacol (1997) 1.16
Evidence for electroneutral sodium chloride cotransport in the cortical thick ascending limb of Henle's loop of rabbit kidney. Pflugers Arch (1983) 1.13
Defective cholinergic Cl(-) secretion and detection of K(+) secretion in rectal biopsies from cystic fibrosis patients. Am J Physiol Gastrointest Liver Physiol (2000) 1.11
Na+ and Cl- conductances in airway epithelial cells: increased Na+ conductance in cystic fibrosis. Pflugers Arch (1995) 1.10
Rescue of the mineralocorticoid receptor knock-out mouse. Pflugers Arch (1999) 1.10
CFTR-mediated inhibition of epithelial Na+ conductance in human colon is defective in cystic fibrosis. Am J Physiol (1999) 1.09
Chloride channel blockers. Methods Enzymol (1990) 1.07
The cAMP-regulated and 293B-inhibited K+ conductance of rat colonic crypt base cells. Pflugers Arch (1996) 1.07
High salt intake increases uroguanylin expression in mouse kidney. Endocrinology (2001) 1.06
Effect of "high ceiling" diuretics on active salt transport in the cortical thick ascending limb of Henle's loop of rabbit kidney. Correlation of chemical structure and inhibitory potency. Pflugers Arch (1983) 1.05
Electrophysiological studies in principal cells of rat cortical collecting tubules. ADH increases the apical membrane Na+-conductance. Pflugers Arch (1987) 1.05
Angiotensin II increases the intracellular calcium activity in podocytes of the intact glomerulus. Kidney Int (2000) 1.04
The cystic fibrosis transmembrane conductance regulator activates aquaporin 3 in airway epithelial cells. J Biol Chem (1999) 1.04
Chloride channels in the luminal membrane of the rectal gland of the dogfish (Squalus acanthias). Properties of the "larger" conductance channel. Pflugers Arch (1987) 1.03
Properties and regulation of chloride channels in cystic fibrosis and normal airway cells. Pflugers Arch (1989) 1.03
Characteristics of apical chloride channels in human colon cells (HT29). Pflugers Arch (1987) 1.03
Ca2+ regulated K+ and non-selective cation channels in the basolateral membrane of rat colonic crypt base cells. Pflugers Arch (1996) 1.03
Properties and regulation of organic cation transport in freshly isolated human proximal tubules. J Biol Chem (2001) 1.01
Specific blockade of slowly activating I(sK) channels by chromanols -- impact on the role of I(sK) channels in epithelia. FEBS Lett (1996) 1.00
Effect of extracellular ATP on contraction, cytosolic calcium activity, membrane voltage and ion currents of rat mesangial cells in primary culture. Br J Pharmacol (1993) 1.00
Bicarbonate permeability of epithelial chloride channels. Pflugers Arch (1991) 1.00
Polarized ion transport during migration of transformed Madin-Darby canine kidney cells. Pflugers Arch (1995) 0.99
KVLQT channels are inhibited by the K+ channel blocker 293B. Pflugers Arch (1997) 0.99
Mineralocorticoid receptor knockout mice: lessons on Na+ metabolism. Kidney Int (2000) 0.99
The cortical thick ascending limb and early distal convoluted tubule in the urinary concentrating mechanism. Kidney Int (1987) 0.99
Luminal ATP induces K+ secretion via a P2Y2 receptor in rat distal colonic mucosa. Pflugers Arch (1998) 0.98
Localization of NaPi-1, a Na-Pi cotransporter, in rabbit kidney proximal tubules. I. mRNA localization by reverse transcription/polymerase chain reaction. Pflugers Arch (1993) 0.98
The cystic fibrosis transmembrane conductance regulator attenuates the endogenous Ca2+ activated Cl- conductance of Xenopus oocytes. Pflugers Arch (1997) 0.98
Deoxycholic acid (DOC) affects the transport properties of distal colon. Pflugers Arch (2000) 0.98
Cloning and function of the rat colonic epithelial K+ channel KVLQT1. J Membr Biol (2001) 0.98
ATP increases [Ca2+]i and ion secretion via a basolateral P2Y-receptor in rat distal colonic mucosa. Pflugers Arch (1997) 0.97
A modified system for in vitro perfusion of isolated renal tubules. Pflugers Arch (1981) 0.97
Small-conductance Cl- channels in HT29 cells: activation by Ca2+, hypotonic cell swelling and 8-Br-cGMP. Pflugers Arch (1992) 0.97
Properties of the lumen membrane of the cortical thick ascending limb of Henle's loop of rabbit kidney. Pflugers Arch (1983) 0.97
Chloride reabsorption in the rabbit cortical thick ascending limb of the loop of Henle. A sodium dependent process. Pflugers Arch (1981) 0.97
Mechanism of NaCl secretion in rectal gland tubules of spiny dogfish (Squalus acanthias). III. Effects of stimulation of secretion by cyclic AMP. Pflugers Arch (1984) 0.96
Properties of single K+ channels in the basolateral membrane of rabbit proximal straight tubules. Pflugers Arch (1987) 0.96
Cl- -channels in the apical cell membrane of the rectal gland "induced" by cAMP. Pflugers Arch (1985) 0.96
Different types of blockers of the intermediate-conductance outwardly rectifying chloride channel in epithelia. Pflugers Arch (1991) 0.96
Potassium channels in the basolateral membrane of the rectal gland of Squalus acanthias. Regulation and inhibitors. Pflugers Arch (1987) 0.95
Blocking kinetics of Cl- channels in colonic carcinoma cells (HT29) as revealed by 5-nitro-2-(3-phenylpropylamino)benzoic acid (NPPB). Biochim Biophys Acta (1988) 0.95
The affinity of the organic cation transporter rOCT1 is increased by protein kinase C-dependent phosphorylation. J Am Soc Nephrol (2000) 0.95
Handling of uric acid by the rat kidney. I. Microanalysis of uric acid in proximal tubular fluid. Pflugers Arch (1971) 0.95
How do loop diuretics act? Drugs (1991) 0.94
Chloride channels in the luminal membrane of rat pancreatic acini. Pflugers Arch (1997) 0.94
Effect of bicarbonate on potassium conductance of isolated perfused rat pancreatic ducts. Pflugers Arch (1991) 0.94
Na+ selective channels in the apical membrane of rabbit late proximal tubules (pars recta). Pflugers Arch (1986) 0.94
Mutations in the putative pore-forming domain of CFTR do not change anion selectivity of the cAMP activated Cl- conductance. FEBS Lett (1995) 0.94
The amiloride inhibitable Na+ conductance of rat colonic crypt cells is suppressed by forskolin. Pflugers Arch (1996) 0.94
Effect of genistein on native epithelial tissue from normal individuals and CF patients and on ion channels expressed in Xenopus oocytes. Br J Pharmacol (2000) 0.94
Principal cells of cortical collecting ducts of the rat are not a route of transepithelial Cl- transport. Pflugers Arch (1990) 0.93
Characterization of potassium channels in respiratory cells. II. Inhibitors and regulation. Pflugers Arch (1989) 0.93
Cystic fibrosis transmembrane conductance regulator activates water conductance in Xenopus oocytes. Pflugers Arch (1997) 0.93
Analysing ion channels with hidden Markov models. Pflugers Arch (1994) 0.92
Macula densa cell function. Kidney Int Suppl (1991) 0.92
KCNE1 reverses the response of the human K+ channel KCNQ1 to cytosolic pH changes and alters its pharmacology and sensitivity to temperature. Pflugers Arch (2000) 0.92
Ion transport processes in apical membranes of epithelia. Fed Proc (1984) 0.92
Synthesis and activity of novel and selective I(Ks)-channel blockers. J Med Chem (2001) 0.92
Diadenosine polyphosphates cause contraction and relaxation in isolated rat resistance arteries. J Pharmacol Exp Ther (2000) 0.91
Angiotensin II increases the cytosolic calcium activity in rat podocytes in culture. Kidney Int (1997) 0.91
Long-term cAMP activation of Na(+)-K(+)-2Cl- cotransporter activity in HT-29 human adenocarcinoma cells. Am J Physiol (1993) 0.91
Cloning of sgk serine-threonine protein kinase from shark rectal gland – a gene induced by hypertonicity and secretagogues. Pflugers Arch (1998) 0.91