Removal of O6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines.

PubWeight™: 1.72‹?› | Rank: Top 3%

🔗 View Article (PMID 7464910)

Published in Nature on January 29, 1981

Authors

R Sklar, B Strauss

Articles citing this

Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli. Microbiol Rev (1984) 19.14

Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine. Proc Natl Acad Sci U S A (1990) 2.19

Replication past O(6)-methylguanine by yeast and human DNA polymerase eta. Mol Cell Biol (2000) 1.95

Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts. Proc Natl Acad Sci U S A (1994) 1.94

Suppression of human DNA alkylation-repair defects by Escherichia coli DNA-repair genes. Proc Natl Acad Sci U S A (1986) 1.45

Cross-linking of DNA induced by chloroethylnitrosourea is presented by O6-methylguanine-DNA methyltransferase. Nucleic Acids Res (1983) 1.42

O6 alkylguanine-DNA alkyltransferase activity in human myeloid cells. J Clin Invest (1985) 1.33

Structural alterations of DNA ligase I in Bloom syndrome. Proc Natl Acad Sci U S A (1987) 1.31

Reduction of the toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene. Proc Natl Acad Sci U S A (1986) 1.31

Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools. Chem Res Toxicol (2011) 1.30

Characterization of the promoter region of the human O6-methylguanine-DNA methyltransferase gene. Nucleic Acids Res (1991) 1.19

Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments. Mol Cell Biol (1991) 1.19

Complementation of sensitivity to alkylating agents in Escherichia coli and Chinese hamster ovary cells by expression of a cloned bacterial DNA repair gene. EMBO J (1986) 1.14

Unique DNA repair properties of a xeroderma pigmentosum revertant. Mol Cell Biol (1987) 1.14

Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes. Proc Natl Acad Sci U S A (1998) 1.08

Effect of partial hepatectomy on removal of O6-methylguanine from alkylated DNA by rat liver extracts. Biochem J (1981) 1.06

Removal of O6-methylguanine from DNA by human liver fractions. Proc Natl Acad Sci U S A (1982) 1.01

DNA-mediated transfer and expression of a human DNA repair gene that demethylates O6-methylguanine. Mol Cell Biol (1985) 0.98

Cloning and expresion of cDNA for rat O6-methylguanine-DNA methyltransferase. Nucleic Acids Res (1991) 0.95

Repair of O6-ethylguanine in DNA protects rat 208F cells from tumorigenic conversion by N-ethyl-N-nitrosourea. Proc Natl Acad Sci U S A (1990) 0.94

Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents. EMBO J (1992) 0.93

Adaptive resynthesis of O6-methylguanine-accepting protein can explain the differences between mammalian cells proficient and deficient in methyl excision repair. Proc Natl Acad Sci U S A (1982) 0.89

Possible depletion of a DNA repair enzyme in human lymphoma cells by subversive repair. Proc Natl Acad Sci U S A (1985) 0.88

Affinity purification and characterization of human O6-alkylguanine-DNA alkyltransferase complexed with BCNU-treated, synthetic oligonucleotide. Nucleic Acids Res (1989) 0.88

Cell cycle perturbation and cell death after exposure of a human lymphoblastoid cell strain to N-methyl-N'-nitro-N-nitrosoguanidine. Am J Pathol (1989) 0.86

MGMT: a personal perspective. DNA Repair (Amst) (2007) 0.86

A reduced rate of bulky DNA adduct removal is coincident with differentiation of human neuroblastoma cells induced by nerve growth factor. Mol Cell Biol (1988) 0.85

Regulation of the capacity for O6-methylguanine removal from DNA in human lymphoblastoid cells studied by cell hybridization. Mol Cell Biol (1982) 0.83

O6-methylguanine-DNA methyltransferase activities in biopsies of human melanoma tumours. Br J Cancer (1995) 0.83

Extracts of chronic lymphocytic leukemia lymphocytes have a high level of DNA repair activity fo O6-methylguanine. Proc Natl Acad Sci U S A (1982) 0.82

The 1987 Walter Hubert lecture. Regulation and deficiencies in DNA repair. Br J Cancer (1987) 0.80

Expression of O(6)-Methylguanine-DNA Methyltransferase Examined by Alkyl-Transfer Assays, Methylation-Specific PCR and Western Blots in Tumors and Matched Normal Tissue. J Cancer Ther (2013) 0.79

Active site amino acid sequence of the bovine O6-methylguanine-DNA methyltransferase. Nucleic Acids Res (1990) 0.78

Transfer of human genes conferring resistance to methylating mutagens, but not to UV irradiation and cross-linking agents, into Chinese hamster ovary cells. Mol Cell Biol (1987) 0.78

Molecular devices for high fidelity of DNA replication and gene expression. Proc Jpn Acad Ser B Phys Biol Sci (2006) 0.77

Immunohistochemical analysis of O(6)-methylguanine-DNA methyltransferase in human melanoma in comparison with skin squamous cell carcinoma. Med Mol Morphol (2013) 0.75

Articles by these authors

Measured enthusiasm: does the method of reporting trial results alter perceptions of therapeutic effectiveness? Ann Intern Med (1992) 7.65

Insertion of nucleotides opposite apurinic/apyrimidinic sites in deoxyribonucleic acid during in vitro synthesis: uniqueness of adenine nucleotides. Biochemistry (1983) 6.68

A model for replication repair in mammalian cells. J Mol Biol (1976) 3.78

The role of DNA polymerase in base substitution mutagenesis on non-instructional templates. Biochimie (1983) 2.74

Repair of damage induced by a monofunctional alkylating agent in a transformable, ultraviolet-sensitive strain of Bacillus subtilis. J Mol Biol (1965) 2.07

The effects of blinding on acceptance of research papers by peer review. JAMA (1994) 2.00

Methylation-induced blocks to in vitro DNA replication. Mutat Res (1985) 1.89

Cell killing and the accumulation of breaks in the DNA of HEp-2 cells incubated in the presence of hydroxyurea. Cancer Res (1970) 1.63

Relation of the repair of damage induced by a monofunctional alkylating agent to the repair of damage induced by ultraviolet light in Bacillus subtilis. Biochem Biophys Res Commun (1965) 1.58

Creating a Canadian stroke system. CMAJ (2001) 1.50

Conservative management of adult epiglottitis. Laryngoscope (1990) 1.43

Computer-based three-dimensional visualization of developmental gene expression. Nat Genet (2000) 1.42

Endoscopic median nerve decompression: early experience. Plast Reconstr Surg (1994) 1.41

Quality of life and psychological well being in polycystic ovary syndrome. Hum Reprod (2007) 1.39

The psychiatric technician: trespasser or welcomed ally? J Psychosoc Nurs Ment Health Serv (1992) 1.39

Repair of DNA studied with a nuclease specific for UV-induced lesions. Proc Natl Acad Sci U S A (1966) 1.36

Repair of alkylation damage: stability of methyl groups in Bacillus subtilis treated with methyl methanesulfonate. J Bacteriol (1970) 1.34

Voluntary weight loss: systematic review of early phase body composition changes. Obes Rev (2011) 1.23

Alkylation damage and its repair. Cold Spring Harb Symp Quant Biol (1968) 1.16

Repression of the insulin receptor promoter by the tumor suppressor gene product p53: a possible mechanism for receptor overexpression in breast cancer. Cancer Res (1996) 1.14

DNA excision-repair deficiency of human peripheral blood lymphocytes treated with chemical carcinogens. Cancer Res (1976) 1.13

Abasic sites from cytosine as termination signals for DNA synthesis. Nucleic Acids Res (1985) 1.13

Doping, drugs and drug abuse among adolescents in the State of Thuringia (Germany): prevalence, knowledge and attitudes. Int J Sports Med (2006) 1.11

Medex: a regional experiment. R I Med J (1971) 1.11

Repair of depurinated DNA in vitro by enzymes purified from human lymphoblasts. Proc Natl Acad Sci U S A (1978) 1.08

Enchancement of nitrosoguanidine mutagenesis by chloramphenicol in Escherichia coli K-12. J Bacteriol (1978) 1.07

[Performance-oriented allocations of financial resources at medical schools: an overview]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz (2009) 1.07

A heat-labile inhibitor of deoxyribonucleic acid degradation in Bacillus subtilis. Biochem Biophys Res Commun (1967) 1.05

Stabilization of the intermediate in frameshift mutation. Mutat Res (1999) 1.03

Role of the uvrE gene product and of inducible O6-methylguanine removal in the induction of mutations by N-methyl-N'-nitro-N-nitrosoguanidine in Escherichia coli. J Mol Biol (1980) 1.02

Guidelines for counselling in infertility: outline version. Hum Reprod (2001) 0.99

Observations on a model of prolifer- ative lung disease. I. Transpulmonary arteriovenous differences of lactate, pyruvate, and glucose. J Clin Invest (1970) 0.98

Actinomycin D inhibition of UV-dark repair in Bacillus subtilis. Biochem Biophys Res Commun (1966) 0.97

Accumulation of an intermediate in DNA synthesis by HEp.2 cells treated with methyl methanesulfonate. Proc Natl Acad Sci U S A (1974) 0.97

The social phobia psychotherapy research network. The first multicenter randomized controlled trial of psychotherapy for social phobia: rationale, methods and patient characteristics. Psychother Psychosom (2008) 0.96

Mutagen stability of alkylation-sensitive mutants of Bacillus subtilis. J Bacteriol (1972) 0.96

Nature of the repair of methyl methanesulfonate-induced damage in Bacillus subtilis. J Bacteriol (1967) 0.95

The measurement of chemically-induced DNA repair synthesis in human cells by BND-cellulose chromatography. Mutat Res (1975) 0.94

Differential efficacy of group and individual/couple psychotherapy with infertile patients. Hum Reprod (2005) 0.94

Heterogeneity of O6-alkylguanine-DNA alkyltransferase activity in peripheral blood lymphocytes: relationship between this activity in lymphocytes and in lymphoblastoid lines from normal controls and from patients with Hodgkin's disease or non-Hodgkin's lymphoma. Cancer Res (1989) 0.94

Dieting and disordered eating in German high school athletes and non-athletes. Scand J Med Sci Sports (2008) 0.92

The Australian Multicenter Trial of Growth Hormone (GH) Treatment in GH-Deficient Adults. J Clin Endocrinol Metab (1998) 0.92

Proliferation of stimulated human peripheral blood lymphocytes: preferential incorporation of concanavalin A by stimulated cells and mitogenic activity. J Immunol (1973) 0.92

[Self-assessment of BMI data : verification of the practicability of a correction formula on a sample of 11- to 13-year-old girls]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz (2011) 0.91

[Hairdex: a tool for evaluation of disease-specific quality of life in patients with hair diseases]. Hautarzt (2001) 0.91

Accumulation of single-stranded regions in DNA and the block to replication in a human cell line alkylated with methyl methane sulfonate. J Mol Biol (1974) 0.90

Amyloid deposition of the breast. AJR Am J Roentgenol (2000) 0.90

Low O6-alkylguanine DNA alkyltransferase activity in the peripheral blood lymphocytes of patients with therapy-related acute nonlymphocytic leukemia. Cancer Res (1988) 0.90

Focal adhesion kinase governs cardiac concentric hypertrophic growth by activating the AKT and mTOR pathways. J Mol Cell Cardiol (2011) 0.89

Prevalence of reduced bone mineral density in systemic lupus erythematosus and the role of steroids. J Rheumatol (1997) 0.89

Differences in the incorporation of bromodeoxyuridine by human lymphoblastoid cell lines. Cell (1975) 0.89

The nature of the alkylation lesion in mammalian cells. Basic Life Sci (1975) 0.88

Efficacy of hypnosis in adults undergoing surgery or medical procedures: a meta-analysis of randomized controlled trials. Clin Psychol Rev (2013) 0.88

Nutritional vitamin B12 deficiency in a breast-fed infant of a vegan-diet mother. Clin Pediatr (Phila) (1986) 0.87

Limited capacity for the removal of O6-methylguanine and its regeneration in a human lymphoma line. Carcinogenesis (1981) 0.87

[Operationalized Psychodynamic Diagnosis in a trial--results of multicenter acceptability and practicability study]. Psychother Psychosom Med Psychol (1996) 0.86

Production of DNA bifilarly substituted with bromodeoxyuridine in the first round of synthesis: branch migration during isolation of cellular DNA. Nucleic Acids Res (1978) 0.86

Nutritional and metabolic consequences of extensive bowel resection. Dig Dis (1986) 0.86

Three year followup of bone mineral density change in premenopausal women with systemic lupus erythematosus. J Rheumatol (1999) 0.86

Autonomic reactivity in the premenstrual phase. Br J Clin Psychol (1983) 0.85

Failure of alkylated HEp.2 cells to replicate newly synthesized DNA. Mutat Res (1971) 0.85

Mutation induced in vitro on a C-8 guanine aminofluorene containing template by a modified T7 DNA polymerase. Biochemistry (1989) 0.85

Comparison of preoperative innervation pattern and postreconstructive urodynamics in the exstrophy-epispadias complex. Urol Int (1997) 0.84

The intermediate in the degradation of DNA alkylated with a monofunctional alkylating agent. Biochim Biophys Acta (1970) 0.84

Selectivity of the excision of alkylation products in a xeroderma pigmentosum-derived lymphoblastoid line. Mutat Res (1979) 0.83

Regulation of the capacity for O6-methylguanine removal from DNA in human lymphoblastoid cells studied by cell hybridization. Mol Cell Biol (1982) 0.83

[The role of resilience for coping in different age groups]. Z Gerontol Geriatr (2011) 0.82

Vulvar pain. Psychological profiles and treatment responses. J Reprod Med (2001) 0.82

Developmental decline in DNA repair in neural retina cells of chick embryos. Persistent deficiency of repair competence in a cell line derived from late embryos. J Cell Biol (1977) 0.82

Glucose requirement for DNA breakdown resulting from treatment of Bacillus subtilis with ultraviolet radiation or methyl methanesulfonate. Mutat Res (1967) 0.81

Choriocarcinoma cells increase the number of differentiating human cytotrophoblasts through an in vitro interaction. J Biol Chem (1991) 0.81

Recovery from ultraviolet- and alkylating-agent-induced damage in Bacillus subtilis. Radiat Res (1966) 0.81

Production of UV-induced frameshift mutations in vitro by DNA polymerases deficient in 3'-->5' exonuclease activity. J Mol Biol (1994) 0.80

Functional expression of human p21(WAF1/CIP1) gene in rat glioma cells suppresses tumor growth in vivo and induces radiosensitivity. Biochem Biophys Res Commun (1997) 0.80

Continued proliferation of mitogen-stimulated human peripheral blood lymphocytes: requirement for the restimulation of progeny. Cell Immunol (1972) 0.80

Intermediates in excision repair by human cells: use of S1 nuclease and benzoylated naphthoylated cellulose to reveal single-strand breaks. Biochemistry (1977) 0.79

Methylmalonyl-CoA mutase induction by cerebral ischemia and neurotoxicity of the mitochondrial toxin methylmalonic acid. J Neurosci (1996) 0.79

Increased repair in DNA growing point regions after treatment of human lymphoma cells with N-methyl-N'-nitro-N-nitrosoguanidine. Mutat Res (1976) 0.79

Successful multiple segment coronary angioplasty: effect of completeness of revascularization in single-vessel multilesions and multivessels. Am Heart J (1990) 0.79

Advance directives in psychiatry. Resolving issues of autonomy and competence. Int J Law Psychiatry (1998) 0.79

Synthesis of retuline. J Org Chem (1966) 0.78

[The effect of brimonidine on the pupillary reflex. A pupillographic study in healthy volunteers]. Ophthalmologe (2005) 0.77

The relationship between O6-alkylguanine alkyltransferase activity and sensitivity to alkylation-induced sister chromatid exchanges in human lymphoblastoid cell lines. Carcinogenesis (1989) 0.77

Attitudes of German infertile couples towards preimplantation genetic diagnosis for different uses: a comparison to international studies. Hum Reprod (2007) 0.77

Termination of synthesis resulting from modifying bases in DNA. IARC Sci Publ (1986) 0.76

[Psychotropic drug-induced changes in sexuality--frequency and relevance in psychiatric practice]. Psychiatr Prax (1984) 0.76

Effectiveness of reducing the risk of eating-related problems using the German school-based intervention program, "Torera", for preadolescent boys and girls. Prev Sci (2014) 0.76

[Validation of the Inventory for Interpersonal Problems (IIP). Results of a representative study in East and West Germany]. Psychother Psychosom Med Psychol (1999) 0.76

The physician extender: his achievement and potential. Bull N Y Acad Med (1976) 0.75

[An empirical study of the phenomenon of the negative attitude to the birth control pill]. Psychother Psychosom Med Psychol (1987) 0.75

[German reconstruction and validation of the Menstrual Attitude Questionnaire]. Psychother Psychosom Med Psychol (1987) 0.75

[Empirical studies of sexual behavior of psychotic patients--a review]. Fortschr Neurol Psychiatr (1986) 0.75

In vitro models for mutagenesis: a role for lesion, polymerase and sequence. Prog Clin Biol Res (1986) 0.75

[Psychoendocrinology of female sexuality]. Gynakologe (1986) 0.75

[Pilot study of the relationship between attachment styles and problem perception in a sample of 9-11 year old children with behavioral disorders]. Prax Kinderpsychol Kinderpsychiatr (2000) 0.75

Nutritional and pulmonary function assessment in chronic obstructive pulmonary disease: Effects of nutritional supplementation. Asia Pac J Clin Nutr (1998) 0.75