Published in J Clin Invest on July 01, 1995
Relaxin is a potent renal vasodilator in conscious rats. J Clin Invest (1999) 1.32
Maternal vasodilation in pregnancy: the emerging role of relaxin. Am J Physiol Regul Integr Comp Physiol (2011) 1.27
Relaxin is essential for renal vasodilation during pregnancy in conscious rats. J Clin Invest (2001) 1.23
Relaxin, a pleiotropic vasodilator for the treatment of heart failure. Heart Fail Rev (2008) 1.13
Unveiling the vasodilatory actions and mechanisms of relaxin. Hypertension (2010) 1.06
Angiogenic growth factors are new and essential players in the sustained relaxin vasodilatory pathway in rodents and humans. Hypertension (2011) 1.06
Emerging role of relaxin in the maternal adaptations to normal pregnancy: implications for preeclampsia. Semin Nephrol (2011) 1.03
Increased activity of cGMP-specific phosphodiesterase (PDE5) contributes to resistance to atrial natriuretic peptide natriuresis in the pregnant rat. J Am Soc Nephrol (2004) 1.03
Increased renal phosphodiesterase-5 activity mediates the blunted natriuretic response to ANP in the pregnant rat. Am J Physiol Renal Physiol (2006) 0.99
International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1-4, the receptors for relaxin family peptides. Pharmacol Rev (2015) 0.97
Sildenafil attenuates placental ischemia-induced hypertension. Am J Physiol Regul Integr Comp Physiol (2013) 0.94
Preeclampsia selectively impairs endothelium-dependent relaxation and leads to oscillatory activity in small omental arteries. J Clin Invest (1998) 0.92
Pregnancy impairs baroreflex control of heart rate in rats: role of insulin sensitivity. Am J Physiol Regul Integr Comp Physiol (2009) 0.91
Molecular mechanisms of preeclampsia. J Pregnancy (2012) 0.90
Receptor-induced dilatation in the systemic and intrarenal adaptation to pregnancy in rats. PLoS One (2009) 0.87
Renal nitric oxide production in rat pregnancy: role of constitutive nitric oxide synthases. Am J Physiol Renal Physiol (2010) 0.84
Increased renal phosphodiesterase-5 activity mediates the blunted natriuretic response to a nitric oxide donor in the pregnant rat. Am J Physiol Renal Physiol (2010) 0.84
The natriuretic and diuretic response to dopamine is maintained during rat pregnancy. Am J Physiol Renal Physiol (2008) 0.83
Isolated mesenteric arteries from pregnant rats show enhanced flow-mediated relaxation but normal myogenic tone. J Physiol (1996) 0.83
The renal circulation in normal pregnancy and preeclampsia: is there a place for relaxin? Am J Physiol Renal Physiol (2014) 0.83
New approaches for managing preeclampsia: clues from clinical and basic research. Clin Ther (2014) 0.83
Renal redox response to normal pregnancy in the rat. Am J Physiol Regul Integr Comp Physiol (2013) 0.80
G-Protein-coupled receptors as potential drug candidates in preeclampsia: targeting the relaxin/insulin-like family peptide receptor 1 for treatment and prevention. Hum Reprod Update (2016) 0.78
Impact of pregnancy on underlying renal disease. Adv Ren Replace Ther (2003) 0.78
Chronic vasodilation produces plasma volume expansion and hemodilution in rats: consequences of decreased effective arterial blood volume. Am J Physiol Renal Physiol (2010) 0.77
Chronic vasodilation increases renal medullary PDE5A and α-ENaC through independent renin-angiotensin-aldosterone system pathways. Am J Physiol Regul Integr Comp Physiol (2013) 0.75
Renal NCC is unchanged in the midpregnant rat and decreased in the late pregnant rat despite avid renal Na+ retention. Am J Physiol Renal Physiol (2015) 0.75
The vasoconstrictor effects of L-NAME, a nitric oxide synthase inhibitor, in pregnant rabbits. Br J Pharmacol (1996) 0.75
GPCRs as potential therapeutic targets in preeclampsia. Drug Discov Today Dis Models (2012) 0.75
Pregnant rats treated with a high-fat/prooxidant Western diet with ANG II and TNF-α are resistant to elevations in blood pressure and renal oxidative stress. Am J Physiol Regul Integr Comp Physiol (2015) 0.75
Functional vascular changes of the kidney during pregnancy in animals: a systematic review and meta-analysis. PLoS One (2014) 0.75
The renal adaptation to pregnancy is now "NOS"-talgic. J Clin Invest (1995) 0.75
Aspects to Consider in Adopting Pregnancy-Specific Reference Intervals. Clin Biochem Rev (2015) 0.75
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81
THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN. J Clin Invest (1945) 27.11
[A simple colorimetric method of inulin determination in renal clearance studies on metabolically normal subjects and diabetics]. Klin Wochenschr (1955) 5.62
Control of regional blood flow by endothelium-derived nitric oxide. Hypertension (1990) 2.93
Blood pressure survey in pregnancy. Clin Sci (1969) 2.42
Identification of increased nitric oxide biosynthesis during pregnancy in rats. FASEB J (1993) 1.86
Endothelial derived relaxing factor controls renal hemodynamics in the normal rat kidney. J Am Soc Nephrol (1990) 1.47
Determinants of aortic cyclic guanosine monophosphate in hypertension induced by chronic inhibition of nitric oxide synthase. J Clin Invest (1992) 1.23
Effects of acute nitric oxide inhibition on rat glomerular microcirculation. Am J Physiol (1991) 1.22
Nitric oxide in the kidney: synthesis, localization, and function. Am J Kidney Dis (1994) 1.15
Changes in water and electrolyte balance, plasma volume and composition during pregnancy in the rat. J Physiol (1982) 1.13
Evidence against the hypothesis that prostaglandins are the vasodepressor agents of pregnancy. Serial studies in chronically instrumented, conscious rats. J Clin Invest (1986) 1.13
Influence of vasopressin on renal hemodynamics in conscious Brattleboro rats. Am J Physiol (1984) 1.12
Plasma level, urinary excretion, and metabolic production of cGMP during gestation in rats. Am J Physiol (1989) 1.11
Influence of oxytocin on renal hemodynamics and electrolyte and water excretion. Am J Physiol (1986) 1.03
Renal hemodynamics during pregnancy in chronically catheterized, conscious rats. Kidney Int (1984) 1.03
Renal effects of acute endothelial-derived relaxing factor blockade are not mediated by angiotensin II. Am J Physiol (1993) 1.02
Systemic hemodynamics and oxygen transport during pregnancy in chronically instrumented, conscious rats. Am J Physiol (1992) 1.00
Influence of oxytocin on renal hemodynamics and sodium excretion. Ann N Y Acad Sci (1993) 0.99
Role of sympathetic nerve activity in the generation of vascular nitric oxide in urethane-anesthetized rats. Hypertension (1991) 0.98
Nitric oxide modulates vascular tone in preglomerular arterioles. Hypertension (1992) 0.94
The effect of pregnancy on kidney function in renal allograft recipients. Kidney Int (1985) 0.92
EDRF-angiotensin II interactions in rat juxtamedullary afferent and efferent arterioles. Am J Physiol (1992) 0.92
Importance of NO/EDRF for glomerular and tubular function: studies in the isolated perfused rat kidney. Kidney Int (1992) 0.92
Locally produced EDRF controls preglomerular resistance and ultrafiltration coefficient. Am J Physiol (1993) 0.91
Progesterone increases glomerular filtration rate, urinary kallikrein excretion and uric acid clearance in normal women. Braz J Med Biol Res (1988) 0.90
Possible mechanisms for changes in renal hemodynamics during pregnancy: studies from animal models. Am J Kidney Dis (1987) 0.88
Glomerular ultrafiltration in the pseudopregnant rat. Am J Physiol (1982) 0.87
Renal effects of cyclooxygenase inhibition in the pregnant rat. Am J Physiol (1987) 0.86
Effects of progesterone and estrogen on the sensitivity to angiotensin II. J Clin Endocrinol Metab (1967) 0.86
The effect of pseudopregnancy on glomerular filtration rate and salt and water reabsorption in the rat. J Physiol (1982) 0.85
RENAL EFFECTS OF ANGIOTENSIN II INFUSIONS IN NORMOTENSIVE PREGNANT AND NONPREGNANT WOMEN. Circ Res (1963) 0.83
Evidence for attenuation of myo-inositol uptake, phosphoinositide turnover and inositol phosphate production in aortic vasculature of rats during pregnancy. J Clin Invest (1991) 0.83
Tubuloglomerular feedback activity in virgin and 12-day-pregnant rats. Am J Physiol (1985) 0.83
Pressor and renal vasoconstrictor effects of NG-nitro-L-arginine as affected by blockade of pressor mechanisms mediated by the sympathetic nervous system, angiotensin, prostanoids and vasopressin. J Pharmacol Exp Ther (1992) 0.82
Renal synthesis and urinary excretion of eicosanoids during pregnancy in rats. Am J Physiol (1987) 0.80
Prostaglandin E2, plasma renin activity, and renal function throughout rabbit pregnancy. J Lab Clin Med (1982) 0.79
Eicosanoid production in rabbit vascular tissues and placentas. Am J Physiol (1990) 0.78
Nitric oxide and pregnancy. Am J Physiol (1997) 2.38
Expression of inflammatory cytokines in placentas from women with preeclampsia. J Clin Endocrinol Metab (2001) 1.94
Altered global gene expression in first trimester placentas of women destined to develop preeclampsia. Placenta (2008) 1.76
Hypoxia stimulates cytokine production by villous explants from the human placenta. J Clin Endocrinol Metab (1997) 1.50
Evidence for the functional activity of hypoxia-inducible transcription factors overexpressed in preeclamptic placentae. Placenta (2004) 1.46
Relaxin is a potent renal vasodilator in conscious rats. J Clin Invest (1999) 1.32
Relaxin is essential for renal vasodilation during pregnancy in conscious rats. J Clin Invest (2001) 1.23
Impaired oxygen-dependent reduction of HIF-1alpha and -2alpha proteins in pre-eclamptic placentae. Placenta (2003) 1.21
Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta. Biol Reprod (2000) 1.19
Selective overexpression of the hypoxia-inducible transcription factor, HIF-2alpha, in placentas from women with preeclampsia. Biol Reprod (2001) 1.19
Evidence against the hypothesis that prostaglandins are the vasodepressor agents of pregnancy. Serial studies in chronically instrumented, conscious rats. J Clin Invest (1986) 1.13
Endothelin and nitric oxide mediate reduced myogenic reactivity of small renal arteries from pregnant rats. Am J Physiol Regul Integr Comp Physiol (2001) 1.05
Renal hemodynamics during pregnancy in chronically catheterized, conscious rats. Kidney Int (1984) 1.03
Influence of oxytocin on renal hemodynamics and electrolyte and water excretion. Am J Physiol (1986) 1.03
Systemic hemodynamics and oxygen transport during pregnancy in chronically instrumented, conscious rats. Am J Physiol (1992) 1.00
Impact of gender and endothelin on renal vasodilation and hyperfiltration induced by relaxin in conscious rats. Am J Physiol Regul Integr Comp Physiol (2000) 0.96
Expression of the erythropoietin receptor by trophoblast cellsin the human placenta. Biol Reprod (1999) 0.89
Possible mechanisms for changes in renal hemodynamics during pregnancy: studies from animal models. Am J Kidney Dis (1987) 0.88
Expression of endothelial nitric oxide synthase by extravillous trophoblast cells in the human placenta. Placenta (2000) 0.87
Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF-alpha proteins. Placenta (2008) 0.87
Comparison of body fluid compartment sizes in Brattleboro homozygous and Long-Evans rats. Am J Physiol (1984) 0.85
Intrinsic tone and passive mechanics of isolated renal arteries from virgin and late-pregnant rats. Am J Physiol (1997) 0.82
Prostaglandins maintain renal vasodilation and hyperfiltration during chronic nitric oxide synthase blockade in conscious pregnant rats. Circ Res (1996) 0.82
Bovine viral diarrhea virus in New World camelids. J Vet Diagn Invest (2000) 0.81
Noninvasive oximetry in the rat. Biomed Instrum Technol (1989) 0.80
Endothelial modulation of renal interlobar arteries from pregnant rats. Am J Physiol (1993) 0.79
Expression of von Hippel Lindau (pVHL) protein in placentae from normal pregnant women and women with preeclampsia. Placenta (2005) 0.78
Renal autoregulation in chronically catheterized conscious rats. Am J Physiol (1984) 0.78
Nitric oxide biosynthesis during pregnancy: implications for circulatory changes. Clin Exp Pharmacol Physiol (1995) 0.77
Metabolism of erythropoietin in conscious pregnant rats. Am J Physiol (1995) 0.76
In vivo and in vitro studies of a putative inhibitor of cyclic guanosine 3',5'-monophosphate production. Proc Soc Exp Biol Med (1991) 0.75
Serum immunoreactive erythropoietin and red blood cell mass during pregnancy in conscious rats. Am J Physiol (1993) 0.75