Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron.

PubWeight™: 1.09‹?› | Rank: Top 10%

🔗 View Article (PMID 7644246)

Published in Pain on April 01, 1995

Authors

H Schwörer1, H Hartmann, G Ramadori

Author Affiliations

1: Department of Medicine, University of Göttingen, Germany.

Articles citing this

The 5-HT3 receptor as a therapeutic target. Expert Opin Ther Targets (2007) 1.86

5-HT3 receptors. Curr Pharm Des (2006) 1.49

Effect of ondansetron, a 5-HT3 receptor antagonist, on fatigue in chronic hepatitis C: a randomised, double blind, placebo controlled study. Gut (2005) 0.96

HTR7 Mediates Serotonergic Acute and Chronic Itch. Neuron (2015) 0.92

Pruritus: management algorithms and experimental therapies. Semin Cutan Med Surg (2011) 0.90

Itch and skin rash from chocolate during fluoxetine and sertraline treatment: case report. BMC Psychiatry (2004) 0.86

Clinical features and management of primary biliary cirrhosis. World J Gastroenterol (2008) 0.85

Four Possible Itching Pathways Related to the TRPV1 Channel, Histamine, PAR-2 and Serotonin. Malays J Med Sci (2013) 0.80

Ondansetron for paediatric uraemic pruritus: a case report. Pediatr Nephrol (2004) 0.78

Fatigue in cholestatic liver disease--a perplexing symptom. Postgrad Med J (2002) 0.77

Treatment Options for Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis. Curr Treat Options Gastroenterol (2003) 0.76

Ondansetron to treat pruritus due to cholestatic jaundice. J Pediatr Pharmacol Ther (2013) 0.76

Why do cholestatic patients itch? Gut (1996) 0.75

Peripheral and spinal 5-HT receptors participate in cholestatic itch and antinociception induced by bile duct ligation in rats. Sci Rep (2016) 0.75

Building a 5-HT3A Receptor Expression Map in the Mouse Brain. Sci Rep (2017) 0.75

5-HT3 receptor antagonists ameliorate fatigue: so much potential, so little knowledge! Gut (2005) 0.75

Pruritus in a patient with advanced cancer successfully treated with continuous infusion of granisetron. Support Care Cancer (2004) 0.75

Articles by these authors

Invasive procedures in children receiving intensive care. BMJ (1993) 4.54

Conformational substates in a protein: structure and dynamics of metmyoglobin at 80 K. Proc Natl Acad Sci U S A (1982) 3.25

Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1. J Exp Med (1985) 2.84

Possible association between Behçet's syndrome and chronic hepatitis C virus infection. N Engl J Med (1995) 2.83

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature (1998) 2.56

Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential. Gastroenterology (1999) 2.30

Thermal expansion of a protein. Biochemistry (1987) 2.25

Falsely negative 99mTc-antigranulocyte immunoscintigraphy and positive 99mTc-HMPAO-labelled leukocyte scan in active Crohn's disease. Possible effects of immunosuppressive therapy? Nuklearmedizin (1995) 2.00

Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver: regulation by TNF-alpha and TGF-beta1. J Hepatol (1999) 1.89

Differential expression of collagen types I, III, and IV by fat-storing (Ito) cells in vitro. Gastroenterology (1992) 1.78

Superiority of the Child-Pugh classification to quantitative liver function tests for assessing prognosis of liver cirrhosis. Scand J Gastroenterol (1989) 1.72

Portosystemic hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in patients with cirrhosis: clinical, laboratory, psychometric, and electroencephalographic investigations. Hepatology (1998) 1.65

Diagnosis and management after life threatening events in infants and young children who received cardiopulmonary resuscitation. BMJ (1993) 1.65

Active syphilis in HIV infection: a multicentre retrospective survey. The German AIDS Study Group (GASG). Genitourin Med (1996) 1.58

Expression of matrix metalloproteinases and their inhibitors during hepatic tissue repair in the rat. Histochem Cell Biol (2000) 1.55

CD95/CD95L-mediated apoptosis of the hepatic stellate cell. A mechanism terminating uncontrolled hepatic stellate cell proliferation during hepatic tissue repair. Am J Pathol (1997) 1.51

A novel management strategy of steroid-free immunosuppression after liver transplantation: efficacy and safety of tacrolimus and mycophenolate mofetil. Transplantation (2001) 1.51

Functional spectrum of sinusoidal endothelial liver cells. Filtration, endocytosis, synthetic capacities and intercellular communication. J Hepatol (1992) 1.51

Long-term outcome of children with acute cerebellitis. Neuropediatrics (2012) 1.50

Analysis of histopathological manifestations of chronic hepatitis C virus infection with respect to virus genotype. Hepatology (1997) 1.49

Clearance of HCV RNA in a chronic hepatitis C virus-infected patient during acute hepatitis B virus superinfection. Liver (1999) 1.49

Localization of liver myofibroblasts and hepatic stellate cells in normal and diseased rat livers: distinct roles of (myo-)fibroblast subpopulations in hepatic tissue repair. Histochem Cell Biol (1999) 1.43

Interferon-alpha treatment of hepatitis C virus-associated mixed cryoglobulinemia. J Hepatol (1997) 1.42

Immunologically unrelated Heliothis sp. and Spodoptera sp. midgut membrane-proteins bind Bacillus thuringiensis CryIA(b) delta-endotoxin. Eur J Biochem (1993) 1.40

[Initial clinical experiences with TIPS (transjugular intrahepatic portasystemic stent-shunt)]. Leber Magen Darm (1995) 1.40

[Current theraphy of oesophageal cancer]. Z Gastroenterol (2004) 1.39

[Portal hypertension--pathophysiology and therapeutic approaches]. Z Gastroenterol (1994) 1.38

Spin state transition in LaCoO3 studied using soft x-ray absorption spectroscopy and magnetic circular dichroism. Phys Rev Lett (2006) 1.36

Gene regulation of heme oxygenase-1 as a therapeutic target. Biochem Pharmacol (2000) 1.36

VIII. Some Considerations upon High Amputation of the Rectum. Ann Surg (1909) 1.34

Expression and regulation of the murine serum amyloid A (SAA) gene in extrahepatic sites. J Immunol (1985) 1.33

Accumulation and cellular localization of fibrinogen/fibrin during short-term and long-term rat liver injury. Gastroenterology (1995) 1.32

Low temperature X-ray investigation of structural distributions in myoglobin. Eur Biophys J (1987) 1.29

Transforming growth factor beta and tumor necrosis factor alpha inhibit both apoptosis and proliferation of activated rat hepatic stellate cells. Hepatology (1999) 1.27

The IGF axis and hepatocarcinogenesis. Mol Pathol (2001) 1.26

Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair. FASEB J (2009) 1.25

Identification and characterization of Heliothis virescens midgut membrane proteins binding Bacillus thuringiensis delta-endotoxins. Eur J Biochem (1991) 1.24

Glial fibrillary acidic protein--a cell type specific marker for Ito cells in vivo and in vitro. J Hepatol (1996) 1.23

Neuronal localization of presenilin-1 and association with amyloid plaques and neurofibrillary tangles in Alzheimer's disease. J Neurosci (1997) 1.20

Release of glucagon-like peptide-1 (GLP-1) by carbohydrates in the perfused rat ileum. Acta Diabetol (1997) 1.19

Expression and regulation of cell adhesion molecules by hepatic stellate cells (HSC) of rat liver: involvement of HSC in recruitment of inflammatory cells during hepatic tissue repair. Am J Pathol (1999) 1.18

Gastrointestinal pH profiles in patients with inflammatory bowel disease. Aliment Pharmacol Ther (1998) 1.17

Enhanced expression of interferon-regulated genes in the liver of patients with chronic hepatitis C virus infection: detection by suppression-subtractive hybridization. J Virol (2001) 1.17

Transforming growth factor beta 1-regulated gene expression of Ito cells. Hepatology (1996) 1.17

Fat storing cells (FSC) of rat liver synthesize and secrete fibronectin. Comparison with hepatocytes. J Hepatol (1987) 1.17

Direct measurement of sound velocity in various specimens of breast tissue. Invest Radiol (2000) 1.13

The bcl, NFkappaB and p53/p21WAF1 systems are involved in spontaneous apoptosis and in the anti-apoptotic effect of TGF-beta or TNF-alpha on activated hepatic stellate cells. Eur J Cell Biol (2001) 1.09

Cell-type-specific expression of neural cell adhesion molecule (N-CAM) in Ito cells of rat liver. Up-regulation during in vitro activation and in hepatic tissue repair. Am J Pathol (1996) 1.08

[On the article Kaireit T et al. "Smartphones now even smarter - possibility of using a "dose warner" "]. Rofo (2013) 1.08

The heat shock cognate protein from Dictyostelium affects actin polymerization through interaction with the actin-binding protein cap32/34. EMBO J (1993) 1.05

Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs). J Pathol (2008) 1.03

Localization and mRNA steady-state level of cellular fibronectin in rat liver undergoing a CCl4-induced acute damage or fibrosis. Biochim Biophys Acta (1993) 1.03

High predictability of a sustained virological response (87%) in chronic hepatitis C virus genotype 1 infection treatment by combined IL28B genotype analysis and γ-glutamyltransferase/alanine aminotransferase ratio: a retrospective single-center study. Digestion (2012) 1.03

Liver fibrosis and altered matrix synthesis. Can J Gastroenterol (2001) 1.03

Effect of heparin and liver heparan sulphate on interaction of HepG2-derived transcription factors and their cis-acting elements: altered potential of hepatocellular carcinoma heparan sulphate. Biochem J (2000) 1.02

F-actin capping by cap32/34 requires heterodimeric conformation and can be inhibited with PIP2. Biochem Biophys Res Commun (1991) 1.02

Characterization of the insulin-like growth factor axis in a human hepatoma cell line (PLC). Carcinogenesis (1998) 1.02

Mechanism of insulin resistance in CCl4-induced cirrhosis of rats. Gastroenterology (1992) 1.02

[Maternal vitamin B12 deficiency: cause for neurological symptoms in infancy]. Z Geburtshilfe Neonatol (2007) 1.02

Intercellular adhesion molecule-1 concentration in sera of patients with acute and chronic liver disease: relationship to disease activity and cirrhosis. Hepatology (1993) 1.01

Carbohydrate metabolism and the liver: actual aspects from physiology and disease. Z Gastroenterol (2007) 1.01

Association of the receptor for immunoglobulin E with an endogenous polypeptide on rat basophilic leukemia cells. J Recept Res (1980) 0.99

Effects of metformin on intestinal 5-hydroxytryptamine (5-HT) release and on 5-HT3 receptors. Naunyn Schmiedebergs Arch Pharmacol (2000) 0.99

V. The Function of the Gastro-Enterostomy Opening in Cases of Permeable Pylorus. Ann Surg (1914) 0.99

Bone morphogenetic protein-6 is expressed in nonparenchymal liver cells and upregulated by transforming growth factor-beta 1. Exp Cell Res (1997) 0.99

Presence of melatonin in the human hepatobiliary-gastrointestinal tract. Life Sci (2001) 0.98

Effect of tumour necrosis factor-alpha on proliferation, activation and protein synthesis of rat hepatic stellate cells. J Hepatol (1997) 0.98

Expression of decorin, transforming growth factor-beta 1, tissue inhibitor metalloproteinase 1 and 2, and type IV collagenases in chronic hepatitis. Am J Clin Pathol (2001) 0.98

ULCER OF THE STOMACH AND OF THE DUODENUM. Ann Surg (1914) 0.98

Guillain-Barré syndrome and human diploid cell rabies vaccine. Lancet (1989) 0.97

Gene expression and regulation of plasminogen activator inhibitor type I in hepatic stellate cells of rat liver. Gastroenterology (1996) 0.97

Decrease of platelet-endothelial cell adhesion molecule 1-gene-expression in inflammatory cells and in endothelial cells in the rat liver following CCl(4)-administration and in vitro after treatment with TNFalpha. Immunol Lett (2000) 0.97

Different gene expression of MDM2, GAGE-1, -2 and FHIT in hepatocellular carcinoma and focal nodular hyperplasia. Br J Cancer (1999) 0.96

Analysis of the IGF axis in preneoplastic hepatic foci and hepatocellular neoplasms developing after low-number pancreatic islet transplantation into the livers of streptozotocin diabetic rats. Lab Invest (2000) 0.96

Direct control of glycogen metabolism in the perfused rat liver by the sympathetic innervation. Eur J Biochem (1982) 0.95

HCV-RNA positivity in peripheral blood mononuclear cells of patients with chronic HCV infection: does it really mean viral replication? World J Gastroenterol (2001) 0.95

Experimental infection of rhesus monkeys with SIV isolated from African green monkeys. Intervirology (1989) 0.95

Inflammation, damage repair and liver fibrosis--role of cytokines and different cell types. Z Gastroenterol (2007) 0.95

Clonal analysis of human T lymphocytes infiltrating the liver in chronic active hepatitis B and primary biliary cirrhosis. Eur J Immunol (1988) 0.95

Characterization of the IGF axis components in isolated rat hepatic stellate cells. Hepatology (1998) 0.94

Synthesis of insulinlike growth factor binding proteins and of the acid-labile subunit in primary cultures of rat hepatocytes, of Kupffer cells, and in cocultures: regulation by insulin, insulinlike growth factor, and growth hormone. Hepatology (1996) 0.94

Phagocytosis and postphagocytic reaction of cord blood and adult blood monocyte after infection with green fluorescent protein-labeled Escherichia coli and group B Streptococci. Cytometry B Clin Cytom (2009) 0.94

Combination of "low-dose" ribavirin and interferon alfa-2a therapy followed by interferon alfa-2a monotherapy in chronic HCV-infected non-responders and relapsers after interferon alfa-2a monotherapy. World J Gastroenterol (2001) 0.94

Carcinosarcoma of the liver. Histopathology (1998) 0.94

Functions of the DnaA protein of Escherichia coli in replication and transcription. Biochim Biophys Acta (1988) 0.94

Situs inversus of donor or recipient in liver transplantation. Transpl Int (1998) 0.94

Quantitative determination of complement components produced by purified hepatocytes. Clin Exp Immunol (1984) 0.94

Insulin-like growth factor-I serum concentrations and patterns of insulin-like growth factor binding proteins in patients with chronic liver disease. J Hepatol (1996) 0.94

Preferential virological response to interferon-alpha 2a in patients with chronic hepatitis C infected by virus genotype 3a and exhibiting a low gamma-GT/ALT ratio. Dig Dis Sci (1996) 0.93

Sinusoidal endothelial liver cells in vitro release endothelin--augmentation by transforming growth factor beta and Kupffer cell-conditioned media. Klin Wochenschr (1991) 0.93