Published in Neurochem Int on July 01, 1995
Gene expression changes in the prefrontal cortex, anterior cingulate cortex and nucleus accumbens of mood disorders subjects that committed suicide. PLoS One (2012) 1.01
Metallothionein and brain inflammation. J Biol Inorg Chem (2011) 0.90
Metallothioneins and brain injury: What transgenic mice tell us. Environ Health Prev Med (2004) 0.77
Influence of zinc sulfate intake on acute ethanol-induced liver injury in rats. World J Gastroenterol (2006) 0.75
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc Natl Acad Sci U S A (2001) 4.58
Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor. Drug Metab Dispos (2001) 1.70
Microglial expression of MHC class II increases in normal aging of nonhuman primates. Neurobiol Aging (1998) 1.54
Overexpression of glutathione S-transferase II and multidrug resistance transport proteins is associated with acquired tolerance to inorganic arsenic. Mol Pharmacol (2001) 1.48
Studies on the mechanism of phenobarbital-enhanced sulfobromophthalein disappearance. J Pharmacol Exp Ther (1968) 1.37
Detection of chemical-induced differential expression of rat hepatic cytochrome P450 mRNA transcripts using branched DNA signal amplification technology. Drug Metab Dispos (2000) 1.34
Increase in metallothionein produced by chemicals that induce oxidative stress. Toxicol Appl Pharmacol (1991) 1.31
Mechanisms of bile formation, hepatic uptake, and biliary excretion. Pharmacol Rev (1984) 1.29
Protective effect of metallothionein against the toxicity of cadmium and other metals(1). Toxicology (2001) 1.23
Comparison of the biochemical alterations elicited in livers from rats treated with carbon tetrachloride, chloroform, 1,1,2-trichloroethane and 1,1,1-trichloroethane. Biochem Pharmacol (1969) 1.20
Tissue mRNA expression of the rat UDP-glucuronosyltransferase gene family. Drug Metab Dispos (2003) 1.18
Biliary flow after microsomal enzyme induction. J Pharmacol Exp Ther (1969) 1.17
Cadmium-induced apoptosis in mouse liver. Toxicol Appl Pharmacol (1998) 1.14
Biliary excretion of drugs in man. Clin Pharmacokinet (1980) 1.11
Protective effect of oleanolic acid against chemical-induced acute necrotic liver injury in mice. Zhongguo Yao Li Xue Bao (1995) 1.11
Selective chemokine mRNA expression following brain injury. Brain Res (1998) 1.11
Role of metallothionein in carcinogenesis. Toxicol Appl Pharmacol (1994) 1.10
Comparison of the effectiveness of several chelators after single administration on the toxicity, excretion, and distribution of cadmium. Toxicol Appl Pharmacol (1981) 1.09
Reduction of thyroid hormone levels and alteration of thyroid function by four representative UDP-glucuronosyltransferase inducers in rats. Toxicol Appl Pharmacol (1994) 1.09
Maximum biliary excretion of bilirubin and sulfobromophthalein during anesthesia-induced alteration of rectal temperature. Proc Soc Exp Biol Med (1967) 1.07
Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1alpha. Biochem Pharmacol (2006) 1.07
Metallothionein (MT)-null mice are sensitive to cisplatin-induced hepatotoxicity. Toxicol Appl Pharmacol (1998) 1.06
trans-Stilbene oxide induces expression of genes involved in metabolism and transport in mouse liver via CAR and Nrf2 transcription factors. Mol Pharmacol (2006) 1.06
Apoptosis in cellular compartments of rat spinal cord after severe contusion injury. J Neurotrauma (1998) 1.05
Cadmium-binding proteins of rat testes. Characterization of a low-molecular-mass protein that lacks identity with metallothionein. Biochem J (1984) 1.04
UDP-glucuronosyltransferase inducers reduce thyroid hormone levels in rats by an extrathyroidal mechanism. Toxicol Appl Pharmacol (1992) 1.03
Differential effects of microsomal enzyme inducers on in vitro thyroxine (T(4)) and triiodothyronine (T(3)) glucuronidation. Toxicol Sci (2000) 1.03
Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels. Drug Metab Dispos (2002) 1.02
Disposition of metals in rats: a comparative study of fecal, urinary, and biliary excretion and tissue distribution of eighteen metals. Toxicol Appl Pharmacol (1986) 1.02
Decreased effectiveness of chelation therapy with time after acute cadmium poisoning. Toxicol Appl Pharmacol (1982) 1.01
Toxicity and distribution of cadmium administered to rats at sublethal doses. Toxicol Appl Pharmacol (1977) 1.00
Metallothionein-I/II knockout mice are sensitive to acetaminophen-induced hepatotoxicity. J Pharmacol Exp Ther (1999) 1.00
Effect of oleanolic acid on hepatic toxicant-activating and detoxifying systems in mice. J Pharmacol Exp Ther (1995) 1.00
Minimal role of metallothionein in decreased chelator efficacy for cadmium. Toxicol Appl Pharmacol (1983) 0.99
Gas-liquid-chromatographic determination of bile acids in bile. Clin Chim Acta (1971) 0.99
Biliary excretion of manganese in rats, rabbits, and dogs. Toxicol Appl Pharmacol (1974) 0.98
Chronic combined exposure to cadmium and arsenic exacerbates nephrotoxicity, particularly in metallothionein-I/II null mice. Toxicology (2000) 0.98
Studies on the increased biliary flow produced by phenobarbital in rats. J Pharmacol Exp Ther (1971) 0.98
Relative in vitro affinity of hepatic metallothionein for metals. Toxicol Lett (1984) 0.98
Plasma disappearance and biliary excretion of indocyanine green in rats, rabbits, and dogs. Toxicol Appl Pharmacol (1969) 0.98
Protective effects of oleanolic acid on acetaminophen-induced hepatotoxicity in mice. J Pharmacol Exp Ther (1993) 0.98
Production of metallothionein and heat-shock proteins in response to metals. Fundam Appl Toxicol (1993) 0.98
Relative effects of various chlorinated hydrocarbons on liver and kidney function in mice. Toxicol Appl Pharmacol (1966) 0.97
Cadmium-induced hepatic and renal injury in chronically exposed rats: likely role of hepatic cadmium-metallothionein in nephrotoxicity. Toxicol Appl Pharmacol (1985) 0.97
Isolation and characterization of metallothionein which is highly concentrated in newborn rat liver. J Biol Chem (1979) 0.96
Induction of metallothionein by adrenocortical steroids. Toxicology (1981) 0.96
Effects of microsomal enzyme inducers on thyroid-follicular cell proliferation, hyperplasia, and hypertrophy. Toxicol Appl Pharmacol (1999) 0.95
Altered subcellular distribution of cadmium following cadmium pretreatment: possible mechanism of tolerance to cadmium-induced lethality. Toxicol Appl Pharmacol (1983) 0.95
Hepatic extraction of bile acids in rats. Biochem Pharmacol (1982) 0.95
Induction of rat UDP-glucuronosyltransferases in liver and duodenum by microsomal enzyme inducers that activate various transcriptional pathways. Drug Metab Dispos (2006) 0.95
Metallothioneins in brain--the role in physiology and pathology. Toxicol Appl Pharmacol (1997) 0.95
Hormonal regulation of renal multidrug resistance-associated proteins 3 and 4 (Mrp3 and Mrp4) in mice. Biochem Pharmacol (2006) 0.94
Alteration of thyroid homeostasis by UDP-glucuronosyltransferase inducers in rats: a dose-response study. J Pharmacol Exp Ther (1995) 0.94
The effect of repeated administration of several chelators on the distribution and excretion of cadmium. Toxicol Appl Pharmacol (1982) 0.94
Studies on the pregnenolone-16 alpha-carbonitrile-inducible form of rat liver microsomal cytochrome P-450 and UDP-glucuronosyltransferase. Biochem Pharmacol (1987) 0.94
Species variation in metabolism, storage, and excretion of sulfobromophthalein. Am J Physiol (1967) 0.94
Does bile acid secretion determine canalicular bile production in rats? Am J Physiol (1971) 0.93
Neurotoxic effects of cadmium in young rats. Toxicol Appl Pharmacol (1982) 0.93
Early and specific expression of monocyte chemoattractant protein-1 in the thalamus induced by cortical injury. Brain Res (2000) 0.93
Induction of metallothionein by arsenicals in mice. Fundam Appl Toxicol (1993) 0.93
The effects of 10 triterpenoid compounds on experimental liver injury in mice. Fundam Appl Toxicol (1994) 0.93
Transgenic mice that overexpress metallothionein-I are protected from cadmium lethality and hepatotoxicity. Toxicol Appl Pharmacol (1995) 0.93
Oleanolic acid protects against cadmium hepatotoxicity by inducing metallothionein. J Pharmacol Exp Ther (1993) 0.92
Induction of digitoxigenin monodigitoxoside UDP-glucuronosyltransferase activity by glucocorticoids and other inducers of cytochrome P-450p in primary monolayer cultures of adult rat hepatocytes and in human liver. J Biol Chem (1986) 0.92
Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites. Drug Metab Dispos (2003) 0.92
Relative effects of various chlorinated hydrocarbons on liver and kidney function in dogs. Toxicol Appl Pharmacol (1967) 0.92
Dose-response effects of various metal ions on rat liver metallothionein, glutathione, heme oxygenase, and cytochrome P-450. Toxicol Appl Pharmacol (1980) 0.92
Increased chemokine gene expression during aging in the murine brain. Brain Res (2001) 0.92
Binding of glutathione-depleting agents to metallothionein. Toxicol Appl Pharmacol (1980) 0.91
Lipoic acid impairs glycine conjugation of benzoic acid and renal excretion of benzoylglycine. Drug Metab Dispos (1996) 0.91
Metallothionein-null mice are more sensitive than wild-type mice to liver injury induced by repeated exposure to cadmium. Toxicol Sci (2000) 0.91
Characterization of metallothionein-I-transgenic mice. Toxicol Appl Pharmacol (1995) 0.91
Depletion of hepatic UDP-glucuronic acid by drugs that are glucuronidated. J Pharmacol Exp Ther (1986) 0.91
Cadmium toxicity and lipid peroxidation in isolated rat hepatocytes. Toxicol Appl Pharmacol (1980) 0.91
The effect of Chinese hepatoprotective medicines on experimental liver injury in mice. J Ethnopharmacol (1994) 0.91
The protective effect of metallothionein on the toxicity of various metals in rat primary hepatocyte culture. Toxicol Appl Pharmacol (1991) 0.91
Metallothionein plays less of a protective role in cadmium-metallothionein-induced nephrotoxicity than in cadmium chloride-induced hepatotoxicity. J Pharmacol Exp Ther (1996) 0.90
Lymphocyte-tropic simian immunodeficiency virus causes persistent infection in the brains of rhesus monkeys. Virology (1995) 0.90
Regional distribution of cortical microglia parallels that of neurofibrillary tangles in Alzheimer's disease. Neurosci Lett (2000) 0.90
National Cancer Institute workshop on the possible roles of metallothionein in carcinogenesis. Cancer Res (1993) 0.90
Species variation in toxication and detoxication of acetaminophen in vivo: a comparative study of biliary and urinary excretion of acetaminophen metabolites. J Pharmacol Exp Ther (1988) 0.89
Glucuronidation and biliary excretion of acetaminophen in rats. J Pharmacol Exp Ther (1984) 0.89
Effect of several metallothionein inducers on oxidative stress defense mechanisms in rats. Toxicology (1995) 0.89
Genetic background but not metallothionein phenotype dictates sensitivity to cadmium-induced testicular injury in mice. Toxicol Appl Pharmacol (2001) 0.89
Species variations in biliary excretion of glutathione-related thiols and methylmercury. Toxicol Appl Pharmacol (1988) 0.88
Induction of metallothionein by steroids in rat primary hepatocyte cultures. Toxicol Appl Pharmacol (1987) 0.88
Metallothionein-null mice are highly susceptible to the hematotoxic and immunotoxic effects of chronic CdCl2 exposure. Toxicol Appl Pharmacol (1999) 0.88
Susceptibility of MT-null mice to chronic CdCl2-induced nephrotoxicity indicates that renal injury is not mediated by the CdMT complex. Toxicol Sci (1998) 0.88
Concentration of metallothionein in major organs of rats after administration of various metals. Fundam Appl Toxicol (1985) 0.88
Effect of microsomal enzyme inducers on the biliary excretion of cardiac glycosides. J Pharmacol Exp Ther (1974) 0.88
Cloning of the full-length coding sequence of rat liver-specific organic anion transporter-1 (rlst-1) and a splice variant and partial characterization of the rat lst-1 gene. Biochem Biophys Res Commun (2000) 0.88
Effects of phenobarbital on the plasma disappearance and biliary excretion of drugs in rats. J Pharmacol Exp Ther (1970) 0.88
Determination of sulfobromophthalein storage and exertory rate in small animals. J Appl Physiol (1967) 0.88
Redistribution of cadmium to blood of rats. Toxicol Appl Pharmacol (1981) 0.87
Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1). Biochem Biophys Res Commun (2000) 0.87
Tissue-specific expression of rat sulfotransferase messenger RNAs. Drug Metab Dispos (1998) 0.87
Morphological correlates of neurological dysfunction in macaques infected with neurovirulent simian immunodeficiency virus. Neuropathol Appl Neurobiol (1999) 0.87
First-pass effect of morphine in rats. J Pharmacol Exp Ther (1977) 0.87
Comparison of methods for estimating hepatic metallothionein in rats. Toxicol Appl Pharmacol (1977) 0.87