Published in Am J Hum Genet on August 01, 1995
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HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families. Nat Genet (1993) 1.50
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Geneticists trace the DNA trail of the first Americans. Science (1993) 1.09
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Analysis of HLA class II haplotypes in the Cayapa Indians of Ecuador: a novel DRB1 allele reveals evidence for convergent evolution and balancing selection at position 86. Am J Hum Genet (1994) 1.01
Major histocompatibility complex class II alleles and haplotypes and blood groups of four Amerindian tribes of northern Colombia. Hum Immunol (1994) 0.90
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Genetic characterization of the Cayapa Indians of Ecuador and their genetic relationships to other Native American populations. Hum Biol (1994) 0.88
Polymorphism in the upstream regulatory region of DQA1 genes and DRB1, QAP, DQA1, and DQB1 haplotypes in the German population. Hum Immunol (1994) 0.87
PCR/oligonucleotide probe typing of HLA class II alleles in a Filipino population reveals an unusual distribution of HLA haplotypes. Am J Hum Genet (1994) 0.85
A genetically controlled pairing anomaly between HLA-DQ alpha and HLA-DQ beta chains. J Immunol (1989) 0.85
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Seven new DPB1 alleles and their population distribution. Tissue Antigens (1994) 0.80
EcoRI, RsaI, and MspI RFLPs of the COL1A2 gene (type I collagen) in the Cayapa, a Native American population of Ecuador. Hum Biol (1994) 0.79
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science (1988) 220.77
Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science (1985) 95.08
Direct cloning and sequence analysis of enzymatically amplified genomic sequences. Science (1986) 19.54
Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus. Proc Natl Acad Sci U S A (1988) 18.72
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Characterization of beta-thalassaemia mutations using direct genomic sequencing of amplified single copy DNA. Nature (1987) 8.58
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HLA and insulin gene associations with IDDM. Genet Epidemiol (1989) 6.53
Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility. Proc Natl Acad Sci U S A (1988) 4.19
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Western Blot analysis of the antigens of Toxoplasma gondii recognized by human IgM and IgG antibodies. J Immunol (1983) 3.53
Lack of association between early exposure to cow's milk protein and beta-cell autoimmunity. Diabetes Autoimmunity Study in the Young (DAISY) JAMA (1996) 3.52
Rapid prenatal diagnosis of sickle cell anemia by a new method of DNA analysis. N Engl J Med (1987) 3.44
A sensitive radioimmunoassay for detecting products translated from cloned DNA fragments. Cell (1978) 3.30
Limited heterogeneity of rearranged T-cell receptor V alpha transcripts in brains of multiple sclerosis patients. Nature (1990) 3.30
A signal, from human mtDNA, of postglacial recolonization in Europe. Am J Hum Genet (2001) 3.28
Newborn screening for HLA markers associated with IDDM: diabetes autoimmunity study in the young (DAISY). Diabetologia (1996) 3.23
Nomenclature for factors of the HLA system, 2010. Tissue Antigens (2010) 3.22
Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes. Proc Natl Acad Sci U S A (1988) 2.99
The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian, multiplex families. Am J Hum Genet (1996) 2.90
Ancestral Asian source(s) of new world Y-chromosome founder haplotypes. Am J Hum Genet (1999) 2.89
HLA class II allelic variation and susceptibility to pemphigus vulgaris. Proc Natl Acad Sci U S A (1988) 2.72
High-resolution, high-throughput HLA genotyping by next-generation sequencing. Tissue Antigens (2009) 2.64
Diagnosis of sickle cell anemia and beta-thalassemia with enzymatically amplified DNA and nonradioactive allele-specific oligonucleotide probes. N Engl J Med (1988) 2.64
Population variation of human mtDNA control region sequences detected by enzymatic amplification and sequence-specific oligonucleotide probes. Am J Hum Genet (1991) 2.56
Preferential PCR amplification of alleles: mechanisms and solutions. PCR Methods Appl (1992) 2.47
Polymorphism, recombination, and linkage disequilibrium within the HLA class II region. J Immunol (1992) 2.39
Polynesian mitochondrial DNAs reveal three deep maternal lineage clusters. Hum Biol (1994) 2.38
Structure, sequence and polymorphism in the HLA-D region. Immunol Rev (1985) 2.16
A multilocus genotyping assay for candidate markers of cardiovascular disease risk. Genome Res (1999) 2.13
Association mapping of disease loci, by use of a pooled DNA genomic screen. Am J Hum Genet (1997) 2.07
Selection for T-cell receptor V beta-D beta-J beta gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis. Nature (1993) 2.01
Genetic differentiation in South Amerindians is related to environmental and cultural diversity: evidence from the Y chromosome. Am J Hum Genet (2001) 2.00
Nomenclature for factors of the HLA system, 1990. Tissue Antigens (1991) 1.98
Disequilibrium pattern analysis. I. Theory. Genetics (1987) 1.92
Nomenclature for factors of the HLA system, 2002. Tissue Antigens (2002) 1.89
Recent origin of HLA-DRB1 alleles and implications for human evolution. Nat Genet (1998) 1.89
Combined use of biallelic and microsatellite Y-chromosome polymorphisms to infer affinities among African populations. Am J Hum Genet (1999) 1.81
A multi-site study using high-resolution HLA genotyping by next generation sequencing. Tissue Antigens (2011) 1.81
Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis. Tissue Antigens (2007) 1.77
HLA-DQ alpha allele and genotype frequencies in various human populations, determined by using enzymatic amplification and oligonucleotide probes. Am J Hum Genet (1990) 1.72
A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles. J Clin Invest (1989) 1.72
The HLA class II locus DPB1 can influence susceptibility to type 1 diabetes. Diabetes (2000) 1.69
Characterization of recombination in the HLA class II region. Am J Hum Genet (1997) 1.69
Quantitative determination of bone marrow transplant engraftment using fluorescent polymerase chain reaction primers for human identity markers. Blood (1995) 1.68
Isolation of a cDNA clone for the human HLA-DR antigen alpha chain by using a synthetic oligonucleotide as a hybridization probe. Proc Natl Acad Sci U S A (1982) 1.64
Multi-locus candidate gene polymorphisms and risk of myocardial infarction: a population-based, prospective genetic analysis. J Thromb Haemost (2006) 1.61
Nomenclature for factors of the HLA system, 1991. WHO Nomenclature Committee for factors of the HLA system. Tissue Antigens (1992) 1.58
Nomenclature for factors of the HLA system, 2004. Tissue Antigens (2005) 1.57
Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans. Genes Immun (2006) 1.56
HLA DR-DQ associations with cervical carcinoma show papillomavirus-type specificity. Nat Genet (1994) 1.52
Initiation of protein synthesis in bacteria at a translational start codon of mamalian cDNA: effects of the preceding nucleotide sequence. Proc Natl Acad Sci U S A (1980) 1.51
HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families. Nat Genet (1993) 1.50
A method for typing polymorphism at the HLA-A locus using PCR amplification and immobilized oligonucleotide probes. Tissue Antigens (1994) 1.49
T-cell receptor V alpha and C alpha alleles associated with multiple and myasthenia gravis. Proc Natl Acad Sci U S A (1989) 1.47
The association of specific HLA class I and II alleles with type 1 diabetes among Filipinos. Tissue Antigens (2002) 1.47
Ancient roots for polymorphism at the HLA-DQ alpha locus in primates. Proc Natl Acad Sci U S A (1989) 1.46
Prevalence of factor V Leiden mutation in non-European populations. Thromb Haemost (1997) 1.45
Rapid typing of HLA-DQB1 DNA polymorphism using nonradioactive oligonucleotide probes and amplified DNA. Immunogenetics (1991) 1.45
Nomenclature for factors of the HLA system, 1998. Tissue Antigens (1999) 1.40
HLA sequence polymorphism and the origin of humans. Science (1996) 1.39
Contrasting evolutionary histories among tightly linked HLA loci. Am J Hum Genet (1986) 1.39
DNA sequence and characterization of human class II major histocompatibility complex beta chains from the DR1 haplotype. Proc Natl Acad Sci U S A (1985) 1.39
Molecular genetic analysis of 178 I-Abm12-reactive T cells. J Exp Med (1989) 1.36
Nomenclature for factors of the HLA system, 1995. Tissue Antigens (1995) 1.34
High throughput HLA genotyping using 454 sequencing and the Fluidigm Access Array™ System for simplified amplicon library preparation. Tissue Antigens (2013) 1.34
HLA class I (A, B, C) and class II (DRB1, DQA1, DQB1, DPB1) alleles and haplotypes in the Han from southern China. Tissue Antigens (2007) 1.32
Association of HLA-DPB1*0301 with IDDM in Mexican-Americans. Diabetes (1996) 1.32
16(th) IHIW : review of HLA typing by NGS. Int J Immunogenet (2013) 1.27
Constrained disequilibrium values and hitchhiking in a three-locus system. Genetics (1998) 1.27
HLA diversity, differentiation, and haplotype evolution in Mesoamerican Natives. Hum Immunol (2001) 1.27
Analysis of HLA-DP allelic sequence polymorphism using the in vitro enzymatic DNA amplification of DP-alpha and DP-beta loci. J Immunol (1988) 1.26
Extended DR3-D6S273-HLA-B haplotypes are associated with increased susceptibility to type 1 diabetes in US Caucasians. Tissue Antigens (2005) 1.25
Rapid HLA-DPB typing using enzymatically amplified DNA and nonradioactive sequence-specific oligonucleotide probes. Immunogenetics (1990) 1.25
Immunological detection and characterization of products translated from cloned DNA fragments. Methods Enzymol (1979) 1.25
High-resolution HLA class I typing in the CEPH families: analysis of linkage disequilibrium among HLA loci. Tissue Antigens (2000) 1.23
Transcriptional regulation of HLA class II and invariant chain genes. J Immunol (1985) 1.23
Multi-locus HLA class I and II allele and haplotype associations with follicular lymphoma. Tissue Antigens (2012) 1.22
Common and well-documented HLA alleles: 2012 update to the CWD catalogue. Tissue Antigens (2013) 1.22
Nomenclature for factors of the HLA system, 2000. Tissue Antigens (2001) 1.21
Identification of an antigen-specific immunoglobulin M antibody associated with acute Toxoplasma infection. Infect Immun (1983) 1.21
Nomenclature for factors of the HLA system, 1994. Tissue Antigens (1994) 1.19
Allelic diversification at the class II DQB locus of the mammalian major histocompatibility complex. Proc Natl Acad Sci U S A (1990) 1.18
Nomenclature for factors of the HLA system, 1996. Tissue Antigens (1997) 1.18
HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM. Diabetes (1995) 1.16
Nomenclature for factors of the HLA system, 1995. Hum Immunol (1995) 1.16