Published in Dev Neurosci on January 01, 1993
Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo 13C NMR. Proc Natl Acad Sci U S A (1999) 2.76
Mice lacking brain/kidney phosphate-activated glutaminase have impaired glutamatergic synaptic transmission, altered breathing, disorganized goal-directed behavior and die shortly after birth. J Neurosci (2006) 1.55
In vivo nuclear magnetic resonance spectroscopy studies of the relationship between the glutamate-glutamine neurotransmitter cycle and functional neuroenergetics. Philos Trans R Soc Lond B Biol Sci (1999) 1.32
Identification of SLC38A7 (SNAT7) protein as a glutamine transporter expressed in neurons. J Biol Chem (2011) 1.15
Maintenance of thalamic epileptiform activity depends on the astrocytic glutamate-glutamine cycle. J Neurophysiol (2009) 1.01
Astrocytic energetics during excitatory neurotransmission: What are contributions of glutamate oxidation and glycolysis? Neurochem Int (2013) 0.94
Is there in vivo evidence for amino acid shuttles carrying ammonia from neurons to astrocytes? Neurochem Res (2012) 0.92
A Role for GAT-1 in Presynaptic GABA Homeostasis? Front Cell Neurosci (2011) 0.88
Proposed cycles for functional glutamate trafficking in synaptic neurotransmission. Neurochem Int (2007) 0.84
Advances in high-field magnetic resonance spectroscopy in Alzheimer's disease. Curr Alzheimer Res (2014) 0.82
Modulation of glutamate transport and receptor binding by glutamate receptor antagonists in EAE rat brain. PLoS One (2014) 0.79
Comparison of alterations in amino acids content in cultured astrocytes or neurons exposed to methylmercury separately or in co-culture. Neurochem Int (2009) 0.77
Comparison of Glutamate Turnover in Nerve Terminals and Brain Tissue During [1,6-(13)C2]Glucose Metabolism in Anesthetized Rats. Neurochem Res (2016) 0.75
Interactive effects of glutamine and gamma-aminobutyric acid on growth performance and skeletal muscle amino acid metabolism of 22-42-day-old broilers exposed to hot environment. Int J Biometeorol (2015) 0.75
Both developmental and metabolic signals activate the promoter of a class I patatin gene. EMBO J (1989) 4.15
Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem (1984) 3.39
Control of GluR1 AMPA receptor function by cAMP-dependent protein kinase. J Neurosci (2000) 3.10
Evidence of the crucial role of sucrose synthase for sink strength using transgenic potato plants (Solanum tuberosum L.). Plant J (1995) 3.08
One of two different ADP-glucose pyrophosphorylase genes from potato responds strongly to elevated levels of sucrose. Mol Gen Genet (1990) 2.79
Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells. Proc Natl Acad Sci U S A (1985) 2.65
The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48
What is the restriction point? Curr Opin Cell Biol (1995) 2.48
Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic B-cells. J Physiol (1993) 2.47
A novel fusion gene, SYT-SSX4, in synovial sarcoma. J Natl Cancer Inst (1999) 2.36
Inositol trisphosphate-dependent periodic activation of a Ca(2+)-activated K+ conductance in glucose-stimulated pancreatic beta-cells. Nature (1991) 2.35
An ethanol inducible gene switch for plants used to manipulate carbon metabolism. Nat Biotechnol (1998) 2.12
Bactericidal antisense effects of peptide-PNA conjugates. Nat Biotechnol (2001) 1.96
Inorganic pyrophosphate content and metabolites in potato and tobacco plants expressing E. coli pyrophosphatase in their cytosol. Planta (1992) 1.86
Functional interactions between neurons and astrocytes I. Turnover and metabolism of putative amino acid transmitters. Prog Neurobiol (1979) 1.81
A small decrease of plastid transketolase activity in antisense tobacco transformants has dramatic effects on photosynthesis and phenylpropanoid metabolism. Plant Cell (2001) 1.79
Glucose and lactate metabolism during brain activation. J Neurosci Res (2001) 1.74
Apoplastic expression of yeast-derived invertase in potato : effects on photosynthesis, leaf solute composition, water relations, and tuber composition. Plant Physiol (1992) 1.74
High affinity glutamate transporters: regulation of expression and activity. Mol Pharmacol (1997) 1.73
Cyclic ADP-ribose in beta cells. Science (1993) 1.71
Amino acid neighbours and detailed conformational analysis of cysteines in proteins. Protein Eng (1999) 1.68
Astrocytes: glutamate producers for neurons. J Neurosci Res (1999) 1.62
Concomitant loss of chromosome 3 and whole arm losses and gains of chromosome 1, 6, or 8 in metastasizing primary uveal melanoma. Invest Ophthalmol Vis Sci (2001) 1.57
Combined expression of glucokinase and invertase in potato tubers leads to a dramatic reduction in starch accumulation and a stimulation of glycolysis. Plant J (1998) 1.56
A moderate decrease of plastid aldolase activity inhibits photosynthesis, alters the levels of sugars and starch, and inhibits growth of potato plants. Plant J (1998) 1.55
Application of an immunodiagnostic method for improving preoperative diagnosis of nodular thyroid lesions. Lancet (2001) 1.54
Co-existence of peptide HI (PHI) and VIP in nerves regulating blood flow and bronchial smooth muscle tone in various mammals including man. Peptides (1984) 1.51
Cloning and expression analysis of a potato cDNA that encodes branching enzyme: evidence for co-expression of starch biosynthetic genes. Mol Gen Genet (1991) 1.51
Protein secondary structure and homology by neural networks. The alpha-helices in rhodopsin. FEBS Lett (1988) 1.50
Two-kidney, two clip renovascular hypertensive rats can be used as stroke-prone rats. Stroke (1998) 1.49
Physical association of starch biosynthetic enzymes with starch granules of maize endosperm. Granule-associated forms of starch synthase I and starch branching enzyme II. Plant Physiol (1996) 1.46
Clinical 1H magnetic resonance spectroscopy of brain metastases at 1.5T and 3T. Acta Radiol (2006) 1.43
Impaired photoassimilate partitioning caused by phloem-specific removal of pyrophosphate can be complemented by a phloem-specific cytosolic yeast-derived invertase in transgenic plants. Plant Cell (1995) 1.42
Analysis of the secondary structure of the human immunodeficiency virus (HIV) proteins p17, gp120, and gp41 by computer modeling based on neural network methods. J Acquir Immune Defic Syndr (1990) 1.41
Analysis of the expression of potato uridinediphosphate-glucose pyrophosphorylase and its inhibition by antisense RNA. Planta (1993) 1.41
[AIDS--knowledge, behavior and attitude at the University of Aarhus in 1990. A questionnaire study]. Ugeskr Laeger (1993) 1.40
Genome screen of late-onset Alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis. Am J Med Genet B Neuropsychiatr Genet (2009) 1.40
Inorganic polyphosphates in the acquisition of competence in Escherichia coli. J Biol Chem (1995) 1.39
Tooth surface recording. Br Dent J (2008) 1.38
Soluble acid invertase determines the hexose-to-sucrose ratio in cold-stored potato tubers. Planta (1996) 1.38
Reverse transcriptase polymerase chain reaction on fine needle aspirates for rapid detection of translocations in synovial sarcoma. Acta Cytol (1998) 1.38
Spinach hexokinase I is located in the outer envelope membrane of plastids. FEBS Lett (1999) 1.37
Iron deficiency and iron overload in Swedish male adolescents. J Intern Med (1995) 1.37
Simulation of protein conformational freedom as a function of pH: constant-pH molecular dynamics using implicit titration. Proteins (1997) 1.37
Separate processes mediate nucleotide-induced inhibition and stimulation of the ATP-regulated K(+)-channels in mouse pancreatic beta-cells. Proc Biol Sci (1991) 1.32
Activation by adrenaline of a low-conductance G protein-dependent K+ channel in mouse pancreatic B cells. Nature (1991) 1.31
Pyruvate carboxylase activity in primary cultures of astrocytes and neurons. J Neurochem (1983) 1.31
Ectopic expression of a tobacco invertase inhibitor homolog prevents cold-induced sweetening of potato tubers. Nat Biotechnol (1999) 1.31
Regulation of carbohydrate partitioning during the interaction of potato virus Y with tobacco. Mol Plant Pathol (2000) 1.29
Syntaxin 1 interacts with the L(D) subtype of voltage-gated Ca(2+) channels in pancreatic beta cells. Proc Natl Acad Sci U S A (1999) 1.29
Antihypertensive effect and side-effects of bendroflumethiazide and propranolol. Acta Med Scand (1976) 1.29
Trafficking of amino acids between neurons and glia in vivo. Effects of inhibition of glial metabolism by fluoroacetate. J Cereb Blood Flow Metab (1997) 1.29
Calcium binding in alpha-amylases: an X-ray diffraction study at 2.1-A resolution of two enzymes from Aspergillus. Biochemistry (1990) 1.29
Direct demonstration by [13C]NMR spectroscopy that glutamine from astrocytes is a precursor for GABA synthesis in neurons. Neurochem Int (1993) 1.28
Neuropeptide Y receptor in pig spleen: binding characteristics, reduction of cyclic AMP formation and calcium antagonist inhibition of vasoconstriction. Eur J Pharmacol (1988) 1.28
Dantrolene prevents glutamate cytotoxicity and Ca2+ release from intracellular stores in cultured cerebral cortical neurons. J Neurochem (1991) 1.27
Simultaneous detection of multiple cytokines from conditioned media and patient's sera by an antibody-based protein array system. Anal Biochem (2001) 1.27
Salicylic acid-independent induction of pathogenesis-related protein transcripts by sugars is dependent on leaf developmental stage. FEBS Lett (1996) 1.26
Human cell lines U-937, THP-1 and Mono Mac 6 represent relatively immature cells of the monocyte-macrophage cell lineage. Leukemia (1994) 1.25
Cytoplasmic calcium transients due to single action potentials and voltage-clamp depolarizations in mouse pancreatic B-cells. EMBO J (1992) 1.24
A truncated version of an ADP-glucose pyrophosphorylase promoter from potato specifies guard cell-selective expression in transgenic plants. Plant Cell (1994) 1.23
Role of N-linked glycosylation in cell-cycle progression and initiation of DNA synthesis in tumor-transformed human fibroblasts. Anticancer Res (1993) 1.23
Inhibition of N-linked glycosylation using tunicamycin causes cell death in malignant cells: role of down-regulation of the insulin-like growth factor 1 receptor in induction of apoptosis. Cancer Res (1997) 1.22
The first immunoglobulin-like neural cell adhesion molecule (NCAM) domain is involved in double-reciprocal interaction with the second immunoglobulin-like NCAM domain and in heparin binding. J Biol Chem (1997) 1.22
PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells. Science (1996) 1.22
Poly-3-hydroxybutyrate/polyphosphate complexes form voltage-activated Ca2+ channels in the plasma membranes of Escherichia coli. Biophys J (1995) 1.21
What distinguishes an esterase from a lipase: a novel structural approach. Biochimie (2000) 1.21
The effect of mannoheptulose on glucose- and pyruvate-stimulated oxygen uptake in normal mouse pancreatic islets. Biochim Biophys Acta (1971) 1.21
Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes. J Neurochem (1996) 1.21
Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons. Brain Res (1989) 1.21
Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes. Diabetologia (2004) 1.20
The development of the avian vertebral column. Anat Embryol (Berl) (2000) 1.19
Neuronal soluble factors differentially regulate the expression of the GLT1 and GLAST glutamate transporters in cultured astroglia. J Neurochem (1997) 1.19
Increased activity of L-type Ca2+ channels exposed to serum from patients with type I diabetes. Science (1993) 1.19
Expression of insulin-like growth factor-1 receptor in synovial sarcoma: association with an aggressive phenotype. Cancer Res (1999) 1.18
How do lipases and esterases work: the electrostatic contribution. J Biotechnol (2001) 1.17
Factors predicting the cumulative outcome of IVF/ICSI treatment: a multivariable analysis of 2450 patients. Hum Reprod (2011) 1.17
Glial-neuronal interactions as studied by cerebral metabolism of [2-13C]acetate and [1-13C]glucose: an ex vivo 13C NMR spectroscopic study. J Neurochem (1995) 1.16
The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome. Cancer Res (1999) 1.16
Design of a microfabricated magnetic cell separator. Electrophoresis (2001) 1.16
Experimental studies of the influence of vigabatrin on the GABA system. Br J Clin Pharmacol (1989) 1.15
Reconstitution of an active lactose carrier in vivo by simultaneous synthesis of two complementary protein fragments. J Bacteriol (1990) 1.14
The high-affinity glutamate transporters GLT1, GLAST, and EAAT4 are regulated via different signalling mechanisms. Neurochem Int (2000) 1.13
Regional cerebral glucose phosphorylation and blood flow after insertion of a microdialysis fiber through the dorsal hippocampus in the rat. J Neurochem (1987) 1.13
Reduction of the cytosolic fructose-1,6-bisphosphatase in transgenic potato plants limits photosynthetic sucrose biosynthesis with no impact on plant growth and tuber yield. Plant J (1996) 1.12
Connexin 43 (cx43) enhances chemotherapy-induced apoptosis in human glioblastoma cells. Int J Cancer (2001) 1.12
A simplified procedure for the subtractive cDNA cloning of photoassimilate-responding genes: isolation of cDNAs encoding a new class of pathogenesis-related proteins. Plant Mol Biol (1995) 1.12
Silanized nucleic acids: a general platform for DNA immobilization. Nucleic Acids Res (2000) 1.11
Glutamate transport and metabolism in astrocytes. Glia (1997) 1.11
Metabolic fate of 14C-labeled glutamate in astrocytes in primary cultures. J Neurochem (1982) 1.11
Molecular determinants of sink strength. Curr Opin Plant Biol (1998) 1.11
Trafficking between glia and neurons of TCA cycle intermediates and related metabolites. Glia (1997) 1.11