Replacement of the conserved G.U with a G-C pair at the cleavage site of the Tetrahymena ribozyme decreases binding, reactivity, and fidelity.

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Published in Biochemistry on November 22, 1994

Authors

A M Pyle1, S Moran, S A Strobel, T Chapman, D H Turner, T R Cech

Author Affiliations

1: Department of Chemistry and Biochemistry, University of Colorado, Boulder 80309.

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