The function of KGF in morphogenesis of epithelium and reepithelialization of wounds.

PubWeight™: 3.07‹?› | Rank: Top 1%

🔗 View Article (PMID 7973639)

Published in Science on November 04, 1994

Authors

S Werner1, H Smola, X Liao, M T Longaker, T Krieg, P H Hofschneider, L T Williams

Author Affiliations

1: Cardiovascular Research Institute, University of California at San Francisco (UCSF) 94143-0130.

Articles citing this

Fibroblast growth factor signalling: from development to cancer. Nat Rev Cancer (2010) 8.55

A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell (2009) 5.40

Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. Proc Natl Acad Sci U S A (1998) 3.27

Protection of the intestinal mucosa by intraepithelial gamma delta T cells. Proc Natl Acad Sci U S A (2002) 2.69

Metalloproteinases and their inhibitors: regulators of wound healing. Int J Biochem Cell Biol (2007) 2.65

Thrombospondin-1 suppresses wound healing and granulation tissue formation in the skin of transgenic mice. EMBO J (2000) 2.44

Cellular and genetic analysis of wound healing in Drosophila larvae. PLoS Biol (2004) 2.39

Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration. Sci Signal (2010) 2.36

Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure. EMBO J (1995) 2.16

Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning. EMBO J (1998) 2.07

c-Met is essential for wound healing in the skin. J Cell Biol (2007) 1.98

Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound. Mol Cell Biol (2002) 1.97

Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat. Proc Natl Acad Sci U S A (1999) 1.95

Establishment of human papillomavirus infection requires cell cycle progression. PLoS Pathog (2009) 1.94

Wound repair and regeneration: mechanisms, signaling, and translation. Sci Transl Med (2014) 1.87

Intratracheal instillation of keratinocyte growth factor decreases hyperoxia-induced mortality in rats. J Clin Invest (1995) 1.68

Impaired wound healing in transgenic mice overexpressing the activin antagonist follistatin in the epidermis. EMBO J (2001) 1.46

Epithelialization in Wound Healing: A Comprehensive Review. Adv Wound Care (New Rochelle) (2014) 1.45

The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development. EMBO J (2007) 1.45

Leptin enhances wound re-epithelialization and constitutes a direct function of leptin in skin repair. J Clin Invest (2000) 1.45

Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing. Mol Cell Biol (2006) 1.45

Epidermal stem cells: the cradle of epidermal determination, differentiation and wound healing. Biol Cell (2005) 1.43

Inducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxia. Proc Natl Acad Sci U S A (2003) 1.41

Aberrant Wound Healing in an Epidermal Interleukin-4 Transgenic Mouse Model of Atopic Dermatitis. PLoS One (2016) 1.41

Gammadelta T cell-induced hyaluronan production by epithelial cells regulates inflammation. J Exp Med (2005) 1.40

Peptide-matrix-mediated gene transfer of an oxygen-insensitive hypoxia-inducible factor-1alpha variant for local induction of angiogenesis. Proc Natl Acad Sci U S A (2006) 1.39

Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1. Am J Pathol (2004) 1.39

Isolation of mouse stromal cells associated with a human tumor using differential diphtheria toxin sensitivity. Am J Pathol (1999) 1.33

Modulation of keratinocyte growth factor and its receptor in reepithelializing human skin. J Exp Med (1995) 1.29

Gene network dynamics controlling keratinocyte migration. Mol Syst Biol (2008) 1.26

Heparin-binding ligands mediate autocrine epidermal growth factor receptor activation In skin organ culture. J Clin Invest (1997) 1.23

Hairy tale of signaling in hair follicle development and cycling. Semin Cell Dev Biol (2012) 1.22

Keratinocyte growth factor is highly overexpressed in inflammatory bowel disease. Am J Pathol (1996) 1.21

Peroxiredoxin 6 is a potent cytoprotective enzyme in the epidermis. Am J Pathol (2006) 1.20

Interactions between stromal cell--derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia. J Clin Invest (1998) 1.19

Activities of the matrix metalloproteinase stromelysin-2 (MMP-10) in matrix degradation and keratinocyte organization in wounded skin. Mol Biol Cell (2004) 1.18

Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia. Am J Pathol (1995) 1.17

Loss of integrin alpha9beta1 results in defects in proliferation, causing poor re-epithelialization during cutaneous wound healing. J Invest Dermatol (2008) 1.17

The novel cytokine p43 stimulates dermal fibroblast proliferation and wound repair. Am J Pathol (2005) 1.16

Tyrosine kinase signalling in breast cancer: fibroblast growth factors and their receptors. Breast Cancer Res (2000) 1.16

Motogenic and morphogenic activity of epithelial receptor tyrosine kinases. J Cell Biol (1996) 1.16

Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration. Proc Natl Acad Sci U S A (2003) 1.15

Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis. J Cell Biol (2010) 1.14

A blood-borne PDGF/VEGF-like ligand initiates wound-induced epidermal cell migration in Drosophila larvae. Curr Biol (2009) 1.13

Peroxiredoxin 6 is required for blood vessel integrity in wounded skin. J Cell Biol (2007) 1.12

An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation. Proc Natl Acad Sci U S A (1996) 1.10

Keratinocyte growth factor in inflammatory bowel disease. Increased mRNA transcripts in ulcerative colitis compared with Crohn's disease in biopsies and isolated mucosal myofibroblasts. Am J Pathol (1997) 1.07

Keratinocyte growth factor improves repair in the injured tracheal epithelium. Am J Respir Cell Mol Biol (2007) 1.06

Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo. Proc Natl Acad Sci U S A (2007) 1.06

Regulation of the expression of stromelysin-2 by growth factors in keratinocytes: implications for normal and impaired wound healing. Biochem J (1996) 1.05

Differential binding of fibroblast growth factor-2 and -7 to basement membrane heparan sulfate: comparison of normal and abnormal human tissues. Am J Pathol (1997) 1.05

Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice. J Clin Invest (2009) 1.03

Altered expression of keratinocyte growth factor and its receptor in psoriasis. Am J Pathol (1997) 1.03

Fibroblast growth factors in epithelial repair and cytoprotection. Philos Trans R Soc Lond B Biol Sci (2004) 1.03

KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin. Development (2009) 1.03

Polyploidization and cell fusion contribute to wound healing in the adult Drosophila epithelium. Curr Biol (2013) 1.01

FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin. J Cell Sci (2012) 1.00

Cellular and Molecular Characteristics of Scarless versus Fibrotic Wound Healing. Dermatol Res Pract (2010) 0.97

Activated hepatic stellate cells express keratinocyte growth factor in chronic liver disease. Am J Pathol (2004) 0.97

Aging alters functionally human dermal papillary fibroblasts but not reticular fibroblasts: a new view of skin morphogenesis and aging. PLoS One (2008) 0.97

A novel type of glutathione peroxidase: expression and regulation during wound repair. Biochem J (1997) 0.95

Silencing of keratinocyte growth factor receptor restores 5-fluorouracil and tamoxifen efficacy on responsive cancer cells. PLoS One (2008) 0.95

p63/p51-induced onset of keratinocyte differentiation via the c-Jun N-terminal kinase pathway is counteracted by keratinocyte growth factor. J Biol Chem (2008) 0.94

Swatting flies: modelling wound healing and inflammation in Drosophila. Dis Model Mech (2011) 0.94

A role for endogenous glucocorticoids in wound repair. EMBO Rep (2002) 0.93

Role of FGFR2-signaling in the pathogenesis of acne. Dermatoendocrinol (2009) 0.92

Recapitulation of morphogenetic cell shape changes enables wound re-epithelialisation. Development (2014) 0.92

Temporal and spatial expression of FGF ligands and receptors during Xenopus development. Dev Dyn (2009) 0.92

Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. Thorax (2011) 0.91

Familial craniosynostosis, anal anomalies, and porokeratosis: CAP syndrome. J Med Genet (1998) 0.91

Beta1 integrin-mediated adhesion signalling is essential for epidermal progenitor cell expansion. PLoS One (2009) 0.90

Cellular and molecular mechanisms of repair in acute and chronic wound healing. Br J Dermatol (2015) 0.90

p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice. J Clin Invest (2012) 0.90

Stem Cell Fate Determination during Development and Regeneration of Ectodermal Organs. Front Physiol (2012) 0.89

A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor. Biochem J (2001) 0.89

Mistargeting hippocampal axons by expression of a truncated Eph receptor. Proc Natl Acad Sci U S A (2002) 0.89

Effects of amniotic membrane suspension in human corneal wound healing in vitro. Mol Vis (2009) 0.88

Ribosomal S6 kinase as a mediator of keratinocyte growth factor-induced activation of Akt in epithelial cells. Mol Biol Cell (2004) 0.86

Sugar-coating wound repair: a review of FGF-10 and dermatan sulfate in wound healing and their potential application in burn wounds. J Burn Care Res (2012) 0.86

Baicalin, a flavonoid, affects the activity of human dermal papilla cells and promotes anagen induction in mice. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.82

Fluorescence-based alternative splicing reporters for the study of epithelial plasticity in vivo. RNA (2012) 0.82

Keratinocyte growth factor induces gene expression signature associated with suppression of malignant phenotype of cutaneous squamous carcinoma cells. PLoS One (2012) 0.82

Fibroblast growth factor 22 is not essential for skin development and repair but plays a role in tumorigenesis. PLoS One (2012) 0.81

Keratinocyte-derived follistatin regulates epidermal homeostasis and wound repair. Lab Invest (2008) 0.81

Stathmin regulates keratinocyte proliferation and migration during cutaneous regeneration. PLoS One (2013) 0.80

Strengthening the skin with topical delivery of keratinocyte growth factor-1 using a novel DNA plasmid. Mol Ther (2014) 0.80

Pten loss induces autocrine FGF signaling to promote skin tumorigenesis. Cell Rep (2014) 0.80

Recombinant peptides for gastrointestinal ulceration: still early days. Gut (1997) 0.79

Mutations in fibroblast growth factor receptors: phenotypic consequences during eukaryotic development. Am J Hum Genet (1995) 0.78

A novel enhancer of the wound healing process: the fibroblast growth factor-binding protein. Am J Pathol (2011) 0.78

Palifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre-clinical models. J Cell Mol Med (2013) 0.77

Murine mentors: transgenic and knockout models of surgical disease. Ann Surg (1999) 0.76

Mesenchymal Stem/Stromal Cells under Stress Increase Osteosarcoma Migration and Apoptosis Resistance via Extracellular Vesicle Mediated Communication. PLoS One (2016) 0.76

Re-epithelialization of cutaneous wounds in adult zebrafish combines mechanisms of wound closure in embryonic and adult mammals. Development (2016) 0.75

Cellular and Molecular Responses to Mechanical Expansion of Tissue. Front Physiol (2016) 0.75

Conditional knockout of N-WASP in mouse fibroblast caused keratinocyte hyper proliferation and enhanced wound closure. Sci Rep (2016) 0.75

Extract of Allium tuberosum Rottler ex Spreng Promoted the Hair Growth through Regulating the Expression of IGF-1. Evid Based Complement Alternat Med (2015) 0.75

Formation of keratinocyte multilayers on filters under airlifted or submerged culture conditions in medium containing calcium, ascorbic acid, and keratinocyte growth factor. Histochem Cell Biol (2016) 0.75

7-Phloroeckol promotes hair growth on human follicles in vitro. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.75

Articles by these authors

Gene transfer into mouse lyoma cells by electroporation in high electric fields. EMBO J (1982) 17.98

Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol (1988) 16.45

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science (1992) 7.49

Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J Exp Med (1999) 6.09

A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc Natl Acad Sci U S A (1998) 5.94

Specific receptor sites for chemotactic peptides on human polymorphonuclear leukocytes. Proc Natl Acad Sci U S A (1977) 5.87

In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc Natl Acad Sci U S A (1999) 5.65

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways. Cell (1992) 5.09

Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor. Cell (1989) 4.86

PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex. Cell (1990) 4.85

cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF beta-receptor. Cell (1991) 4.76

Structural and functional diversity in the FGF receptor multigene family. Adv Cancer Res (1993) 4.67

A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. Nature (1998) 4.52

Role of phosphatidylinositol kinase in PDGF receptor signal transduction. Science (1989) 4.21

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science (1997) 4.19

Signalling by receptor tyrosine kinases. Annu Rev Biochem (1993) 4.11

Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway. Nature (1993) 3.88

Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor. Science (1989) 3.83

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways. Mol Cell Biol (1996) 3.82

Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization. J Clin Invest (1988) 3.76

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain. Mol Cell Biol (1997) 3.52

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase. Science (1995) 3.42

Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing. J Biol Chem (1995) 3.30

A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine. Mol Cell Biol (1991) 3.20

Inhibition of minicircular DNA replication in Escherichia coli 15 by rifampicin. Nat New Biol (1972) 3.10

Expression in Escherichia coli of hepatitis B virus DNA sequences cloned in plasmid pBR322. Nature (1979) 3.03

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc Natl Acad Sci U S A (1993) 3.01

Large induction of keratinocyte growth factor expression in the dermis during wound healing. Proc Natl Acad Sci U S A (1992) 2.89

A disease severity scale for systemic sclerosis: development and testing. J Rheumatol (1999) 2.85

Differential regulation of pro-inflammatory cytokines during wound healing in normal and glucocorticoid-treated mice. Cytokine (1996) 2.84

An alternative to SH2 domains for binding tyrosine-phosphorylated proteins. Science (1994) 2.80

Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors. Proc Natl Acad Sci U S A (2001) 2.77

Regulation of chemotaxis by the platelet-derived growth factor receptor-beta. Nature (1994) 2.71

Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex. Mol Cell Biol (1990) 2.71

c-myc gene expression is stimulated by agents that activate protein kinase C and does not account for the mitogenic effect of PDGF. Cell (1985) 2.69

PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling. Nat Cell Biol (2001) 2.69

Molecular cloning of the genome of a cardiotropic Coxsackie B3 virus: full-length reverse-transcribed recombinant cDNA generates infectious virus in mammalian cells. Proc Natl Acad Sci U S A (1985) 2.67

Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription. Proc Natl Acad Sci U S A (1998) 2.66

The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain. Mol Cell Biol (1991) 2.63

Platelet-derived growth factor receptors form a high affinity state in membrane preparations. Kinetics and affinity cross-linking studies. J Biol Chem (1984) 2.61

Impaired mechanical stability, migration and contractile capacity in vimentin-deficient fibroblasts. J Cell Sci (1998) 2.60

Identification of beta-adrenergic receptors in human lymphocytes by (-) (3H) alprenolol binding. J Clin Invest (1976) 2.58

Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5. Proc Natl Acad Sci U S A (1995) 2.58

Craniofacial tissue engineering by stem cells. J Dent Res (2006) 2.48

Isolation of an additional member of the fibroblast growth factor receptor family, FGFR-3. Proc Natl Acad Sci U S A (1991) 2.48

Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis. Nature (1992) 2.46

Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse. Development (1992) 2.34

Diverse forms of a receptor for acidic and basic fibroblast growth factors. Mol Cell Biol (1990) 2.33

Evidence for the platelet-derived growth factor-stimulated tyrosine phosphorylation of the platelet-derived growth factor receptor in vivo. Immunopurification using a monoclonal antibody to phosphotyrosine. J Biol Chem (1984) 2.33

Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth. Proc Natl Acad Sci U S A (1993) 2.32

Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER. Science (1996) 2.31

Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2. EMBO J (1997) 2.26

Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function. Proc Natl Acad Sci U S A (1999) 2.25

Recombinant nidogen consists of three globular domains and mediates binding of laminin to collagen type IV. EMBO J (1991) 2.23

Activation of Raf-1 by 14-3-3 proteins. Nature (1994) 2.22

Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd. Proc Natl Acad Sci U S A (2001) 2.22

Isolation and characterization of a ribonuclease 3 deficient mutant of Escherichia coli. Mol Gen Genet (1973) 2.19

Successful repair in utero of a fetal diaphragmatic hernia after removal of herniated viscera from the left thorax. N Engl J Med (1990) 2.17

Cloning of cDNA of major antigen of foot and mouth disease virus and expression in E. coli. Nature (1981) 2.14

A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF. Nature (1988) 2.13

Thyroid hormone regulation of beta-adrenergic receptor number. J Biol Chem (1977) 2.13

Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung. EMBO J (1994) 2.13

Integrin alpha 2 beta 1 is upregulated in fibroblasts and highly aggressive melanoma cells in three-dimensional collagen lattices and mediates the reorganization of collagen I fibrils. J Cell Biol (1991) 2.08

Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation. Proc Natl Acad Sci U S A (1995) 2.06

ralGDS family members interact with the effector loop of ras p21. Mol Cell Biol (1994) 2.05

In situ detection of enteroviral genomes in myocardial cells by nucleic acid hybridization: an approach to the diagnosis of viral heart disease. Proc Natl Acad Sci U S A (1987) 2.05

The HBV X-ORF encodes a transactivator: a potential factor in viral hepatocarcinogenesis. Oncogene (1988) 2.02

Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK. Curr Biol (1998) 2.02

Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha. J Biol Chem (1998) 2.01

Long-range motional restrictions in a multidomain zinc-finger protein from anisotropic tumbling. Science (1995) 2.01

Cardiac myocyte hypertrophy is associated with c-myc protooncogene expression. Proc Natl Acad Sci U S A (1986) 2.00

The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor. Mol Cell Biol (1992) 1.99

Monocyte chemoattractant protein-1 is sufficient for the chemotaxis of monocytes and lymphocytes in transgenic mice but requires an additional stimulus for inflammatory activation. J Immunol (1997) 1.99

Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation. Mol Cell Biol (1998) 1.93

Impaired wound healing in embryonic and adult mice lacking vimentin. J Cell Sci (2000) 1.92

The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity. Mol Cell Biol (1994) 1.91

Biosynthesis of two subunits of type IV procollagen and of other basement membrane proteins by a human tumor cell line. Eur J Biochem (1980) 1.90

Integration of hepatitis B virus DNA: evidence for integration in the single-stranded gap. Cell (1983) 1.87

Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair. EMBO J (1999) 1.84

Identification of alpha-adrenergic receptors in uterine smooth muscle membranes by [3H]dihydroergocryptine binding. J Biol Chem (1976) 1.84

Autocrine stimulation of intracellular PDGF receptors in v-sis-transformed cells. Science (1988) 1.83

A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis. Proc Natl Acad Sci U S A (1995) 1.82

Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrins. J Cell Biol (1995) 1.82

Relation between component parts of fibrocystic disease complex and breast cancer. J Natl Cancer Inst (1978) 1.82

Inhibiting effect of procollagen peptides on collagen biosynthesis in fibroblast cultures. J Biol Chem (1979) 1.80

Blockade of autocrine stimulation in simian sarcoma virus-transformed cells reverses down-regulation of platelet-derived growth factor receptors. Proc Natl Acad Sci U S A (1984) 1.80

Alpha-adrenergic receptor identification by (3H)dihydroergocryptine binding. Science (1976) 1.79

Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation. EMBO J (1993) 1.78

Liposomes as gene carriers: efficient transformation of mouse L cells by thymidine kinase gene. Science (1982) 1.78

Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities. Mol Cell Biol (1992) 1.77

Processing of the platelet-derived growth factor receptor. Biosynthetic and degradation studies using anti-receptor antibodies. J Biol Chem (1987) 1.76

Molecular basis for specific recognition of both RNA and DNA by a zinc finger protein. Science (1993) 1.75

Fetal hydrops and death from sacrococcygeal teratoma: rationale for fetal surgery. Am J Obstet Gynecol (1989) 1.74

Activated phosphatidylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocation in 3T3-L1 adipocytes. J Biol Chem (1996) 1.71

Acidic and basic fibroblast growth factors stimulate tyrosine kinase activity in vivo. J Biol Chem (1988) 1.70

The preS2/S region of integrated hepatitis B virus DNA encodes a transcriptional transactivator. Nature (1990) 1.69