Published in Circulation on August 01, 1994
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Evidence and consequences of the central role of the kidneys in the pathophysiology of sympathetic hyperactivity. Front Physiol (2012) 0.95
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Correlates of left ventricular mass in hypertensive Nigerians: an echocardiographic study. Cardiovasc J Afr (2010) 0.78
The role of the kidney and the sympathetic nervous system in hypertension. Pediatr Nephrol (2014) 0.75
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Genetic dissection of complex traits. Science (1994) 29.54
Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data. Am J Hum Genet (2000) 11.47
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Who's afraid of epistasis? Nat Genet (1996) 4.24
Genome-wide association study of bipolar disorder in European American and African American individuals. Mol Psychiatry (2009) 3.64
Telomere length inversely correlates with pulse pressure and is highly familial. Hypertension (2000) 3.32
"White coat" versus "sustained" borderline hypertension in Tecumseh, Michigan. Hypertension (1990) 3.30
The Polycomb-group gene eed is required for normal morphogenetic movements during gastrulation in the mouse embryo. Development (1998) 2.90
Lymphoproliferative lesions of the ocular adnexa. Analysis of 112 cases. Ophthalmology (1998) 2.60
Multiple phenotype modeling in gene-mapping studies of quantitative traits: power advantages. Am J Hum Genet (1998) 2.50
Blood pressure crisis following withdrawal of clonidine (Catapres, Catapresan), with special reference to arterial and urinary catecholamine levels, and suggestions for acute management. Am Heart J (1973) 2.17
Analysis of coronary angioplasty practice in the United States with an insurance-claims data base. Circulation (1993) 2.16
Home blood pressure determination. Value in borderline ("labile") hypertension. JAMA (1974) 2.16
A genomic-systems biology map for cardiovascular function. Science (2001) 2.09
Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. Mol Psychiatry (2012) 2.07
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The 1993 guidelines for the management of mild hypertension: memorandum from a WHO/ISH meeting. Blood Press (1993) 2.03
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Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants. Mol Psychiatry (2012) 1.84
Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach. Mol Psychiatry (2004) 1.76
Dental caries and microbial acid production in twins. Caries Res (2005) 1.73
Genetic dissection of complex traits. Nat Genet (1996) 1.72
Home blood pressure monitoring. Arch Intern Med (2000) 1.71
Discovery and validation of blood biomarkers for suicidality. Mol Psychiatry (2013) 1.69
Mechanism of action of antipruritic drugs. Br Med J (Clin Res Ed) (1983) 1.68
Identification of blood biomarkers for psychosis using convergent functional genomics. Mol Psychiatry (2009) 1.68
High heart rate: a risk factor for cardiovascular death in elderly men. Arch Intern Med (1999) 1.62
Alcohol intake and treatment responsiveness of psoriasis: a prospective study. J Am Acad Dermatol (1993) 1.60
Type II diabetes, essential hypertension, and obesity as "syndromes of impaired genetic homeostasis": the "thrifty genotype" hypothesis enters the 21st century. Perspect Biol Med (1998) 1.57
Heart rate and the cardiovascular risk. J Hypertens (1997) 1.57
An extreme-sib-pair genome scan for genes regulating blood pressure. Am J Hum Genet (1999) 1.56
Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation. Virology (1996) 1.56
Mapping loci for pentylenetetrazol-induced seizure susceptibility in mice. J Neurosci (1999) 1.52
Extreme selection strategies in gene mapping studies of oligogenic quantitative traits do not always increase power. Hum Hered (1998) 1.52
A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa. Mol Psychiatry (2010) 1.52
Are left ventricular mass, geometry and function related to vascular changes and/or insulin resistance in long-standing hypertension? ICARUS: a LIFE substudy. J Hum Hypertens (2003) 1.51
Elevated heart rate: a major risk factor for cardiovascular disease. Clin Exp Hypertens (2005) 1.49
Reflex sympathetic activation induces acute insulin resistance in the human forearm. Hypertension (1993) 1.48
Twins. Novel uses to study complex traits and genetic diseases. Trends Genet (2000) 1.47
Lead, hypertension, and the renin-angiotensin system in rats. J Lab Clin Med (1982) 1.45
A genome-wide search for chromosomal loci linked to mental health wellness in relatives at high risk for bipolar affective disorder among the Old Order Amish. Proc Natl Acad Sci U S A (1998) 1.45
Longitudinal analysis of heritability for dental caries traits. J Dent Res (2005) 1.44
Predictors of new-onset diabetes mellitus in hypertensive patients: the VALUE trial. J Hum Hypertens (2008) 1.44
Genetic regulation of commitment to interleukin 4 production by a CD4(+) T cell-intrinsic mechanism. J Exp Med (1998) 1.44
Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants. Heart Rhythm (2012) 1.43
Genetic analysis of NIDDM. The study of quantitative traits. Diabetes (1996) 1.40
Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice. Immunity (1997) 1.38
beta-adrenergic receptor gene polymorphisms and beta-blocker treatment outcomes in hypertension. Clin Pharmacol Ther (2008) 1.37
Suicidal ideation in psoriasis. Int J Dermatol (1993) 1.37
Stature, drive for thinness and body dissatisfaction: a study of males and females from a non clinical sample. Can J Psychiatry (1993) 1.34
Identification of additional variants within the human dopamine transporter gene provides further evidence for an association with bipolar disorder in two independent samples. Mol Psychiatry (2006) 1.33
Diagnostic significance of abdominal murmurs. N Engl J Med (1967) 1.29
The Losartan Intervention For Endpoint reduction (LIFE) in Hypertension study: rationale, design, and methods. The LIFE Study Group. Am J Hypertens (1997) 1.28
Hemodynamic effects of acute and prolonged beta-adrenergic blockade in essential hypertension. Acta Med Scand (1974) 1.28
Sex-determining genes on mouse autosomes identified by linkage analysis of C57BL/6J-YPOS sex reversal. Nat Genet (1996) 1.27
Selected methodological issues in meiotic mapping of obesity genes in humans: issues of power and efficiency. Behav Genet (1997) 1.27
Emotional and familial determinants of elevated blood pressure in black and white adolescent females. J Psychosom Res (1987) 1.25
Depression modulates pruritus perception: a study of pruritus in psoriasis, atopic dermatitis, and chronic idiopathic urticaria. Psychosom Med (1994) 1.25
Ventilation and metabolism among rat strains. J Appl Physiol (1985) (1997) 1.24
Relationship between cardiac output and peripheral resistance in borderline hypertension. Circulation (1971) 1.23
Influence of age on the hemodynamic response to exercise. Circulation (1967) 1.22
Relationship of tachycardia with high blood pressure and metabolic abnormalities: a study with mixture analysis in three populations. Hypertension (1997) 1.22
Hormonal responses to cardiac tamponade: inhibition of release of atrial natriuretic factor despite elevation of atrial pressures. Circulation (1987) 1.19
Mild high-renin essential hypertension. Neurogenic human hypertension? N Engl J Med (1977) 1.18
Neurohumoral and metabolic effects of short-term dietary NaCl restriction in men. Relationship to salt-sensitivity status. Am J Hypertens (1991) 1.15
Mapping murine loci for seizure response to kainic acid. Mamm Genome (1997) 1.15
Role of parasympathetic inhibition in the hyperkinetic type of borderline hypertension. Circulation (1971) 1.15
A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls. Diabetes (2000) 1.15
Pruritus in psoriasis. A prospective study of some psychiatric and dermatologic correlates. Arch Dermatol (1988) 1.15
A genome-wide scan for loci linked to forearm bone mineral density. Hum Genet (1999) 1.14
Impact of ethnicity on left ventricular mass and relative wall thickness in essential hypertension. Am J Cardiol (1998) 1.12
Hemodynamic studies in patients with borderline blood pressure elevation. Circulation (1968) 1.11
Hyperkinetic borderline hypertension in Tecumseh, Michigan. J Hypertens (1991) 1.10
Hemodynamic responses to tilt and beta-adrenergic blockade in young patients with borderline hypertension. Circulation (1970) 1.10
Relationship of the electrocardiographic strain pattern to left ventricular structure and function in hypertensive patients: the LIFE study. Losartan Intervention For End point. J Am Coll Cardiol (2001) 1.10
Relationships between metrics of visit-to-visit variability of blood pressure. J Hum Hypertens (2013) 1.08
There are no racial, age, sex, or weight differences in the effect of salt on blood pressure in salt-sensitive hypertensive patients. Arch Intern Med (1997) 1.07
Easy money? Health cost savings resulting from the switch from a branded drug to a low-cost generic drug in the same class. Int J Clin Pract (2011) 1.07
Baseline characteristics in relation to electrocardiographic left ventricular hypertrophy in hypertensive patients: the Losartan intervention for endpoint reduction (LIFE) in hypertension study. The Life Study Investigators. Hypertension (2000) 1.07
Lack of association between a biallelic polymorphism in the adducin gene and blood pressure in whites and African Americans. Am J Hypertens (2000) 1.07
Artefacts in measurement of blood pressure and lack of target organ involvement in the assessment of patients with treatment-resistant hypertension. Ann Intern Med (1990) 1.06
Association of tachycardia with morbidity and mortality: pathophysiological considerations. J Hum Hypertens (1997) 1.06
Quantitative trait loci on chromosomes 1, 2, 3, 4, 8, 9, 11, 12, and 18 control variation in levels of T and B lymphocyte subpopulations. Am J Hum Genet (2002) 1.03
Promoter polymorphisms in ACE (angiotensin I-converting enzyme) associated with clinical outcomes in hypertension. Clin Pharmacol Ther (2008) 1.03
The association of borderline hypertension with target organ changes and higher coronary risk. Tecumseh Blood Pressure study. JAMA (1990) 1.03
The international database of self-recorded blood pressures in normotensive and untreated hypertensive subjects. Blood Press Monit (1999) 1.03
Effect of beta-adrenergic blockade on plasma volume in human subjects. Proc Soc Exp Biol Med (1972) 1.03
Marine debris and human impacts on sea turtles in southern Brazil. Mar Pollut Bull (2001) 1.02
Autonomic imbalance, hypertension, and cardiovascular risk. Am J Hypertens (2000) 1.02
Mechanism of increased alpha adrenergic vasoconstriction in human essential hypertension. J Clin Invest (1987) 1.02
Influence of race and dietary salt on the antihypertensive efficacy of an angiotensin-converting enzyme inhibitor or a calcium channel antagonist in salt-sensitive hypertensives. Hypertension (1998) 1.02
The alpha1 Na,K-ATPase gene is a susceptibility hypertension gene in the Dahl salt-sensitiveHSD rat. J Clin Invest (1998) 1.01
Effect of beta adrenoceptor antagonists on baroreceptor reflex sensitivity in hypertension. Clin Pharmacol Ther (1977) 1.01
Autonomic nervous cardiovascular regulation in borderline hypertension. Am J Cardiol (1975) 1.01