Published in Development on June 01, 1994
Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest (2003) 41.22
Development of monocytes, macrophages, and dendritic cells. Science (2010) 12.86
CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clin Invest (2005) 10.44
Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury. Proc Natl Acad Sci U S A (2004) 5.89
Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression. Nat Med (2011) 5.54
Langerhans cells arise from monocytes in vivo. Nat Immunol (2006) 5.46
Trophic macrophages in development and disease. Nat Rev Immunol (2009) 5.37
Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E. Proc Natl Acad Sci U S A (1995) 4.31
A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS One (2009) 3.86
Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J Exp Med (1999) 3.78
The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy. J Exp Med (2004) 3.56
Identification of a receptor required for the anti-inflammatory activity of IVIG. Proc Natl Acad Sci U S A (2008) 3.55
Macrophages define the invasive microenvironment in breast cancer. J Leukoc Biol (2008) 3.02
Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells. J Leukoc Biol (2010) 2.71
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia. Nat Immunol (2012) 2.62
M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med (2009) 2.29
Macrophages Facilitate Electrical Conduction in the Heart. Cell (2017) 2.10
Activated macrophages promote Wnt signalling through tumour necrosis factor-alpha in gastric tumour cells. EMBO J (2008) 2.05
Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits. PLoS One (2011) 1.92
Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and beta-catenin. Nat Immunol (2009) 1.88
Colony stimulating factor-1 dependence of paneth cell development in the mouse small intestine. Gastroenterology (2009) 1.82
Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation. J Exp Med (2011) 1.78
Cyclin D1 governs adhesion and motility of macrophages. Mol Biol Cell (2003) 1.71
Colony-stimulating factor-1 signaling suppresses renal crystal formation. J Am Soc Nephrol (2014) 1.60
CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure. Gastroenterology (2015) 1.59
Colony-stimulating factor-1 transfection of myoblasts improves the repair of failing myocardium following autologous myoblast transplantation. Cardiovasc Res (2008) 1.54
Colony stimulating factor 1 is required for mammary gland development during pregnancy. Proc Natl Acad Sci U S A (1994) 1.53
The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation. Dev Biol (2012) 1.50
Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment. Cell Host Microbe (2015) 1.47
Osteopontin deficiency produces osteoclast dysfunction due to reduced CD44 surface expression. Mol Biol Cell (2003) 1.46
Coordinate regulation of tissue macrophage and dendritic cell population dynamics by CSF-1. J Exp Med (2011) 1.43
Expression of colony-stimulating factor 1 receptor during prostate development and prostate cancer progression. Proc Natl Acad Sci U S A (2002) 1.40
Colony-stimulating factor-1 promotes kidney growth and repair via alteration of macrophage responses. Am J Pathol (2011) 1.37
Lymph node macrophages. J Innate Immun (2012) 1.36
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages. Cell (2014) 1.30
Factors regulating microglia activation. Front Cell Neurosci (2013) 1.26
Fcgamma receptor-dependent effector mechanisms regulate CD19 and CD20 antibody immunotherapies for B lymphocyte malignancies and autoimmunity. Springer Semin Immunopathol (2006) 1.24
Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages. Blood (2012) 1.24
The PCH family member MAYP/PSTPIP2 directly regulates F-actin bundling and enhances filopodia formation and motility in macrophages. Mol Biol Cell (2005) 1.22
Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development (2010) 1.22
CSF-1 receptor structure/function in MacCsf1r-/- macrophages: regulation of proliferation, differentiation, and morphology. J Leukoc Biol (2008) 1.19
Circulating CSF-1 promotes monocyte and macrophage phenotypes that enhance lupus nephritis. J Am Soc Nephrol (2009) 1.18
Genetic and pharmacological targeting of CSF-1/CSF-1R inhibits tumor-associated macrophages and impairs BRAF-induced thyroid cancer progression. PLoS One (2013) 1.18
Regulation of macrophage development and function in peripheral tissues. Nat Rev Immunol (2015) 1.16
Aberrant macrophage and neutrophil population dynamics and impaired Th1 response to Listeria monocytogenes in colony-stimulating factor 1-deficient mice. Infect Immun (2001) 1.15
Epithelia: lymphocyte interactions in the gut. Immunol Rev (2007) 1.15
Glycoengineering of therapeutic antibodies enhances monocyte/macrophage-mediated phagocytosis and cytotoxicity. J Immunol (2014) 1.13
Regulation of steady-state neutrophil homeostasis by macrophages. Blood (2010) 1.12
CSF-1 receptor signaling in myeloid cells. Cold Spring Harb Perspect Biol (2014) 1.10
Protein tyrosine phosphatase phi regulates paxillin tyrosine phosphorylation and mediates colony-stimulating factor 1-induced morphological changes in macrophages. Mol Cell Biol (2001) 1.09
IL-34 induces the differentiation of human monocytes into immunosuppressive macrophages. antagonistic effects of GM-CSF and IFNγ. PLoS One (2013) 1.09
Transcriptional diversity during monocyte to macrophage differentiation. Immunol Lett (2008) 1.06
Bone marrow-derived cells serve as proangiogenic macrophages but not endothelial cells in wound healing. Blood (2011) 1.06
Survival of monocytes and macrophages and their role in health and disease. Front Biosci (Landmark Ed) (2009) 1.06
Increased serum enzyme levels associated with kupffer cell reduction with no signs of hepatic or skeletal muscle injury. Am J Pathol (2011) 1.06
Guardians of the Gut - Murine Intestinal Macrophages and Dendritic Cells. Front Immunol (2015) 1.06
MCP-1 deficiency delays regression of pathologic retinal neovascularization in a model of ischemic retinopathy. Invest Ophthalmol Vis Sci (2008) 1.05
Factors and networks that underpin early hematopoiesis. Semin Immunol (2011) 1.03
Sunlight triggers cutaneous lupus through a CSF-1-dependent mechanism in MRL-Fas(lpr) mice. J Immunol (2008) 1.02
Microglia: key elements in neural development, plasticity, and pathology. J Neuroimmune Pharmacol (2013) 1.02
Sialoadhesin - a macrophage-restricted marker of immunoregulation and inflammation. Immunology (2013) 1.02
The diverse functions of Src family kinases in macrophages. Front Biosci (2008) 1.01
IL-34 and CSF-1: similarities and differences. J Bone Miner Metab (2013) 0.96
Developmental and functional significance of the CSF-1 proteoglycan chondroitin sulfate chain. Blood (2005) 0.96
Meox2Cre-mediated disruption of CSF-1 leads to osteopetrosis and osteocyte defects. Bone (2011) 0.94
M2 macrophage polarisation is associated with alveolar formation during postnatal lung development. Respir Res (2013) 0.93
Macrophage Migration and Its Regulation by CSF-1. Int J Cell Biol (2012) 0.93
Interkeukin-34, a cytokine crucial for the differentiation and maintenance of tissue resident macrophages and Langerhans cells. Eur J Immunol (2014) 0.92
Diabetic Csf1(op/op) mice lacking macrophages are protected against the development of delayed gastric emptying. Cell Mol Gastroenterol Hepatol (2016) 0.92
The establishment of B versus T cell identity. Trends Immunol (2014) 0.92
Molecular control of monocyte development. Cell Immunol (2014) 0.92
Receptor-type protein-tyrosine phosphatase ζ is a functional receptor for interleukin-34. J Biol Chem (2013) 0.91
Macrophages: gatekeepers of tissue integrity. Cancer Immunol Res (2013) 0.91
Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis. J Clin Immunol (2011) 0.91
Macrophages and CSF-1: implications for development and beyond. Organogenesis (2013) 0.90
Selective reduction in microglia density and function in the white matter of colony-stimulating factor-1-deficient mice. J Neurosci Res (2009) 0.89
Of blood cells and the nervous system: hematopoiesis in the Drosophila larva. Fly (Austin) (2012) 0.88
Origin, development, and homeostasis of tissue-resident macrophages. Immunol Rev (2014) 0.88
Adaptor protein Lnk inhibits c-Fms-mediated macrophage function. J Leukoc Biol (2010) 0.87
CKIP-1 regulates macrophage proliferation by inhibiting TRAF6-mediated Akt activation. Cell Res (2014) 0.87
Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice. Proc Natl Acad Sci U S A (2012) 0.86
Receptor Tyrosine Kinase and Tyrosine Kinase Inhibitors: New Hope for Success in Multiple Sclerosis Therapy. Innov Clin Neurosci (2014) 0.86
Development of a specific system for targeting protein to metallophilic macrophages. Proc Natl Acad Sci U S A (2004) 0.86
Hypoxia enhances the proliferative response of macrophages to CSF-1 and their pro-survival response to TNF. PLoS One (2012) 0.86
Expression of macrophage colony-stimulating factor and its receptor in hepatic granulomas of Kupffer-cell-depleted mice. Am J Pathol (1997) 0.85
Cell replication in craniofacial periosteum: appositional vs. resorptive sites. J Anat (2011) 0.85
Effects of macrophage colony-stimulating factor on macrophages and their related cell populations in the osteopetrosis mouse defective in production of functional macrophage colony-stimulating factor protein. Am J Pathol (1996) 0.84
Colony-stimulating factor 1-dependent resident macrophages play a regulatory role in fighting Escherichia coli fecal peritonitis. Infect Immun (1996) 0.84
CSF-1 receptor-dependent colon development, homeostasis and inflammatory stress response. PLoS One (2013) 0.84
Colony-stimulating factor-1-responsive macrophage precursors reside in the amphibian (Xenopus laevis) bone marrow rather than the hematopoietic subcapsular liver. J Innate Immun (2013) 0.83
The macrophage system in the intestinal muscularis externa during inflammation: an immunohistochemical and quantitative study of osteopetrotic mice. Histochem Cell Biol (2008) 0.82
Colony-stimulating factor 1-dependent cells protect against systemic infection with Listeria monocytogenes but facilitate neuroinvasion. Infect Immun (2002) 0.82
Colony-stimulating factor-1-dependent macrophage functions regulate the maternal decidua immune responses against Listeria monocytogenes infections during early gestation in mice. Infect Immun (2008) 0.82
The function of the conserved regulatory element within the second intron of the mammalian Csf1r locus. PLoS One (2013) 0.81
Effects of dyslipidaemia on monocyte production and function in cardiovascular disease. Nat Rev Cardiol (2017) 0.81
Colony-stimulating Factor-1 Receptor is Required for Nurse-like Cell Survival in Chronic Lymphocytic Leukemia. Clin Cancer Res (2016) 0.80
Concise Review: Macrophages: Versatile Gatekeepers During Pancreatic β-Cell Development, Injury, and Regeneration. Stem Cells Transl Med (2015) 0.79
Macrophage Ablation Reduces M2-Like Populations and Jeopardizes Tumor Growth in a MAFIA-Based Glioma Model. Neoplasia (2015) 0.79
CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves. Sci Rep (2016) 0.78
The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1. Cell (1985) 10.17
Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med (2001) 9.99
c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science (1994) 5.97
Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy. Cell (1982) 5.19
Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse. Proc Natl Acad Sci U S A (1990) 5.05
Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells. J Biol Chem (1977) 4.63
Hyperthermia in combined treatment of cancer. Lancet Oncol (2002) 4.41
CSF-1--a mononuclear phagocyte lineage-specific hemopoietic growth factor. J Cell Biochem (1983) 3.31
The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit. Nat Genet (1998) 3.31
Meiotic pachytene arrest in MLH1-deficient mice. Cell (1996) 3.18
Postnatal mammary gland development requires macrophages and eosinophils. Development (2000) 3.10
Activation of human macrophages. Comparison of other cytokines with interferon-gamma. J Exp Med (1984) 3.02
The macrophage colony-stimulating factor, CSF-1. Methods Enzymol (1985) 2.91
Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages. J Cell Sci (1997) 2.79
Current use of bisphosphonates in oncology. International Bone and Cancer Study Group. J Clin Oncol (1998) 2.73
Mammalian MutS homologue 5 is required for chromosome pairing in meiosis. Nat Genet (1999) 2.62
Anti-colony-stimulating factor-1 antibody staining in primary breast adenocarcinomas correlates with marked inflammatory cell infiltrates and prognosis. J Natl Cancer Inst (1994) 2.58
Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors. J Clin Invest (1993) 2.52
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. Genes Dev (2000) 2.49
Th1 and Th2 cytokine secretion patterns in murine candidiasis: association of Th1 responses with acquired resistance. Infect Immun (1991) 2.46
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility. Cell (1997) 2.46
Isolation and characterization of a cloned growth factor dependent macrophage cell line, BAC1.2F5. J Cell Physiol (1987) 2.42
Neutralizing antibody to interleukin 4 induces systemic protection and T helper type 1-associated immunity in murine candidiasis. J Exp Med (1992) 2.37
Colony-stimulating factor (CSF) radioimmunoassay: detection of a CSF subclass stimulating macrophage production. Proc Natl Acad Sci U S A (1979) 2.35
Anomalous origin of the right vertebral artery: review of the literature and case report of right vertebral artery origin distal to the left subclavian artery. AJNR Am J Neuroradiol (1999) 2.34
Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo. Science (1969) 2.30
High-frequency transfection of CHO cells using polybrene. Somat Cell Mol Genet (1986) 2.29
Apparent role of the macrophage growth factor, CSF-1, in placental development. Nature (1988) 2.22
Diphosphonates inhibit formation of calcium phosphate crystals in vitro and pathological calcification in vivo. Science (1969) 2.20
Stuttering: high-level mistranslation in animal and bacterial cells. Proc Natl Acad Sci U S A (1978) 2.15
Stimulation of macrophage plasminogen activator activity by colony-stimulating factors. J Cell Physiol (1980) 2.15
Specific interaction of murine colony-stimulating factor with mononuclear phagocytic cells. J Cell Biol (1980) 2.12
Characterization and cloning of the E11 antigen, a marker expressed by rat osteoblasts and osteocytes. Bone (1996) 2.11
Intraaneurysmal flow: evaluation with Doppler guidewires. AJNR Am J Neuroradiol (1996) 2.09
The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation. EMBO J (1999) 2.08
Production of colony-stimulating factors (CSFs) during infection: separate determinations of macrophage-, granulocyte-, granulocyte-macrophage-, and multi-CSFs. Infect Immun (1988) 2.04
Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse. Endocrinology (1990) 2.02
Regulation of colony-stimulating factor 1 during pregnancy. J Exp Med (1986) 2.00
Distribution of cells bearing receptors for a colony-stimulating factor (CSF-1) in murine tissues. J Cell Biol (1981) 1.99
Role of infiltrated leucocytes in tumour growth and spread. Br J Cancer (2004) 1.98
Impairment of macrophage colony-stimulating factor production and lack of resident bone marrow macrophages in the osteopetrotic op/op mouse. J Bone Miner Res (1990) 1.97
The interaction of 125I-colony-stimulating factor-1 with bone marrow-derived macrophages. J Biol Chem (1986) 1.92
Early osteoarthritic changes of human femoral head cartilage subsequent to femoro-acetabular impingement. Osteoarthritis Cartilage (2003) 1.91
Magnetic resonance cholangiopancreatography-guided unilateral endoscopic stent placement for Klatskin tumors. Gastrointest Endosc (2001) 1.90
Regulation of very primitive, multipotent, hemopoietic cells by hemopoietin-1. Cell (1986) 1.89
Use of dermestid beetles for cleaning bones. Calcif Tissue Int (1980) 1.88
Inductive heating of ferrimagnetic particles and magnetic fluids: physical evaluation of their potential for hyperthermia. 1993. Int J Hyperthermia (2009) 1.87
Liver tumors: comparison of MR imaging with Gd-EOB-DTPA and Gd-DTPA. Radiology (1996) 1.86
Effect of ethane-1-hydroxy-1,1-diphosphonate (EHDP) and dichloromethylene diphosphonate (Cl 2 MDP) on the calcification and resorption of cartilage and bone in the tibial epiphysis and metaphysis of rats. Calcif Tissue Res (1973) 1.85
Distribution of mutations around rearranged heavy-chain antibody variable-region genes. Mol Cell Biol (1990) 1.83
Macrophages specifically regulate the concentration of their own growth factor in the circulation. Proc Natl Acad Sci U S A (1987) 1.82
Drug smuggling by ingested cocaine-filled packages: conventional x-ray and ultrasound. Abdom Imaging (1995) 1.79
Expression of the human c-fms proto-oncogene product (colony-stimulating factor-1 receptor) on peripheral blood mononuclear cells and choriocarcinoma cell lines. J Clin Invest (1986) 1.77
Inorganic pyrophosphate in plasma, urine, and synovial fluid of patients with pyrophosphate arthropathy (chondrocalcinosis or pseudogout). Lancet (1970) 1.77
Temporal expression and location of colony-stimulating factor 1 (CSF-1) and its receptor in the female reproductive tract are consistent with CSF-1-regulated placental development. Proc Natl Acad Sci U S A (1989) 1.77
The binding of pyrophosphate and two diphosphonates by hydroxyapatite crystals. Calcif Tissue Res (1973) 1.77
Inductive heating of ferrimagnetic particles and magnetic fluids: physical evaluation of their potential for hyperthermia. Int J Hyperthermia (1993) 1.77
Transforming growth factor beta3 induces cell death during the first stage of mammary gland involution. Development (2000) 1.70
Progesterone inhibits estrogen-induced cyclin D1 and cdk4 nuclear translocation, cyclin E- and cyclin A-cdk2 kinase activation, and cell proliferation in uterine epithelial cells in mice. Mol Cell Biol (1999) 1.69
Factors regulating macrophage production and growth: identity of colony-stimulating factor and macrophage growth factor. J Exp Med (1976) 1.69
c-Cbl is transiently tyrosine-phosphorylated, ubiquitinated, and membrane-targeted following CSF-1 stimulation of macrophages. J Biol Chem (1996) 1.69
Pigs expressing salivary phytase produce low-phosphorus manure. Nat Biotechnol (2001) 1.68
Colony stimulating factor and the regulation of granulopoiesis and macrophage production. Fed Proc (1975) 1.68
Effect of pyrophosphate on hydroxyapatite and its implications in calcium homeostasis. Nature (1966) 1.68
Effects of magnetic fluid hyperthermia (MFH) on C3H mammary carcinoma in vivo. Int J Hyperthermia (1998) 1.67
Human colony-stimulating factor (CSF-1) radioimmunoassay: resolution of three subclasses of human colony-stimulating factors. Blood (1981) 1.67
Cellular uptake of magnetic fluid particles and their effects on human adenocarcinoma cells exposed to AC magnetic fields in vitro. Int J Hyperthermia (1997) 1.66
Induction of macrophage production and proliferation by a purified colony stimulating factor. Nature (1978) 1.66
Genetic analysis of chromosome pairing, recombination, and cell cycle control during first meiotic prophase in mammals. Endocr Rev (2006) 1.65
Effects of human recombinant CSF-GM and highly purified CSF-1 on the formation of multinucleated cells with osteoclast characteristics in long-term bone marrow cultures. J Bone Miner Res (1986) 1.64
Structure-function studies of a colony stimulating factor (CSF-1). J Biol Chem (1982) 1.64
T1 alpha protein is developmentally regulated and expressed by alveolar type I cells, choroid plexus, and ciliary epithelia of adult rats. Am J Respir Cell Mol Biol (1996) 1.64
Pyrophosphate and diphosphonates in calcium metabolism and their possible role in renal failure. Arch Intern Med (1969) 1.64
Correction by CSF-1 of defects in the osteopetrotic op/op mouse suggests local, developmental, and humoral requirements for this growth factor. Exp Hematol (1991) 1.62
Delayed hematopoietic development in osteopetrotic (op/op) mice. J Exp Med (1993) 1.62
Synergism between hemopoietic growth factors (HGFs) detected by their effects on cells bearing receptors for a lineage specific HGF: assay of hemopoietin-1. J Cell Physiol (1985) 1.61
cDNA cloning and expression of murine macrophage colony-stimulating factor from L929 cells. Proc Natl Acad Sci U S A (1988) 1.60
Methods for the purification, assay, characterization and target cell binding of a colony stimulating factor (CSF-1). J Immunol Methods (1981) 1.60
Hepatocellular carcinoma in association with hepatic focal nodular hyperplasia. Acta Radiol (2006) 1.59
Bisphosphonates act on rat bone resorption through the mediation of osteoblasts. J Clin Invest (1993) 1.58
Partial purification and some properties of the factor in normal and leukaemic human urine stimulating mouse bone marrow colony growth in vitro. Aust J Exp Biol Med Sci (1969) 1.58
Elongation factor-1 alpha is an overexpressed actin binding protein in metastatic rat mammary adenocarcinoma. J Cell Sci (1996) 1.56
Inorganic pyrophosphate in plasma in normal persons and in patients with hypophosphatasia, osteogenesis imperfecta, and other disorders of bone. J Clin Invest (1971) 1.55
The biology of CSF-1 and its receptor. Curr Top Microbiol Immunol (1992) 1.55
The regulation of mononuclear phagocyte entry into S phase by the colony stimulating factor CSF-1. J Cell Physiol (1985) 1.55
Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the RAF-1 proto-oncogene product. EMBO J (1990) 1.55
The trophoblast is a component of the innate immune system during pregnancy. Nat Med (2000) 1.55