Structure-activity relationships for contact allergenic potential of gamma,gamma-dimethyl-gamma-butyrolactone derivatives. 1. Synthesis and electrophilic reactivity studies of alpha-(omega-substituted-alkyl)-gamma,gamma-dimethyl-gamma-butyrolacton es and correlation of skin sensitization potential and cross-sensitization patterns with structure.

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Published in Chem Res Toxicol on October 04, 1994

Authors

C Franot1, D W Roberts, R G Smith, D A Basketter, C Benezra, J P Lepoittevin

Author Affiliations

1: Laboratoire de Dermatochimie associé au CNRS, Université Louis Pasteur, CHU, Strasbourg, France.

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