Published in Exp Cell Res on July 01, 1975
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Stratification, specialization, and proliferation of primary keratinocyte cultures. Evidence of a functioning in vitro epidermal cell system. J Cell Biol (1978) 1.40
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Selective surface radioiodination of keratinocytes in primary culture labels a 59 kD keratin and other surface proteins. Arch Dermatol Res (1989) 0.75
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Expression of collagenase-3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase. J Cell Sci (2000) 1.50
Phenotypic and genotypic characteristics of a cell line from a squamous cell carcinoma of human skin. J Natl Cancer Inst (1982) 1.49
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Preservation of morphological, functional, and karyotypic traits during long-term culture and in vivo passage of two human skin squamous cell carcinomas. Cancer Res (1983) 1.42
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Effect of growth environment on spatial expression of involucrin by human epidermal keratinocytes. Arch Dermatol Res (1987) 1.36
Growth and differentiation characteristics of transformed keratinocytes from mouse and human skin in vitro and in vivo. J Invest Dermatol (1983) 1.36
Dynamics of basement membrane formation by keratinocyte-fibroblast interactions in organotypic skin culture. Exp Cell Res (1998) 1.33
Sustained nontumorigenic phenotype correlates with a largely stable chromosome content during long-term culture of the human keratinocyte line HaCaT. Genes Chromosomes Cancer (1997) 1.32
Organotypic keratinocyte cocultures in defined medium with regular epidermal morphogenesis and differentiation. J Invest Dermatol (1999) 1.32
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Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones. Differentiation (1989) 1.30
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Autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor in human gliomas with tumor progression. Am J Pathol (1999) 1.16
Differential modulation of epidermal keratinization in immortalized (HaCaT) and tumorigenic human skin keratinocytes (HaCaT-ras) by retinoic acid and extracellular Ca2+. Differentiation (1993) 1.14
Environmental induction of differentiation-specific keratins in malignant mouse keratinocyte lines. Eur J Cell Biol (1986) 1.14
Keratins of the human hair follicle: "hyperproliferative" keratins consistently expressed in outer root sheath cells in vivo and in vitro. Differentiation (1987) 1.12
Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization. Proc Natl Acad Sci U S A (1999) 1.11
Formation of epidermis after reimplantation of pure primary epidermal cell cultures from perinatal mouse skin. J Natl Cancer Inst (1974) 1.11
Expression and functional significance of vascular endothelial growth factor receptors in human tumor cells. Lab Invest (1999) 1.11
Normal keratinocytes suppress early stages of neoplastic progression in stratified epithelium. Cancer Res (1998) 1.06
Suppression in vivo of human papillomavirus type 18 E6-E7 gene expression in nontumorigenic HeLa X fibroblast hybrid cells. J Virol (1990) 1.01
Histomorphological and biochemical differentiation capacity in organotypic co-cultures of primary gingival cells. J Periodontal Res (1997) 1.00
Arachidonic acid and prostaglandin E2 release and enhanced cell proliferation induced by the phorbol ester TPA in a murine epidermal cell line. Cancer Lett (1981) 0.99
Epidermal morphogenesis and keratin expression in c-Ha-ras-transfected tumorigenic clones of the human HaCaT cell line. Cancer Res (1991) 0.97
Mesenchyme-mediated and endogenous regulation of growth and differentiation of human skin keratinocytes derived from different body sites. Differentiation (1990) 0.96
Modifications of cell cycle controlling nuclear proteins by transforming growth factor beta in the HaCaT keratinocyte cell line. Oncogene (1992) 0.94
TGF-beta isoforms are differentially expressed in increasing malignant grades of HaCaT keratinocytes, suggesting separate roles in skin carcinogenesis. J Pathol (2000) 0.94
Expression of 5-lipoxygenase in differentiating human skin keratinocytes. Proc Natl Acad Sci U S A (1995) 0.94
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Mouse epidermal cell cultures. I. Isolation and cultivation of epidermal cells from adult mouse skin. J Invest Dermatol (1974) 0.92
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Constitutive expression of G-CSF and GM-CSF in human skin carcinoma cells with functional consequence for tumor progression. Int J Cancer (1999) 0.91
Tumorigenic conversion of immortal human skin keratinocytes (HaCaT) by elevated temperature. Oncogene (1999) 0.91
Characteristics of chemically transformed mouse epidermal cells in vitro and in vivo. Bull Cancer (1978) 0.91
Sensitization of human keratinocytes to killing by parvovirus H-1 takes place during their malignant transformation but does not require them to be tumorigenic. Carcinogenesis (1989) 0.90
Plasminogen activator in differentiating mouse keratinocytes. J Invest Dermatol (1983) 0.90
Cell interactions control the fate of malignant keratinocytes in an organotypic model of early neoplasia. J Invest Dermatol (1999) 0.90
Step-wise progression in human skin carcinogenesis in vitro involves mutational inactivation of p53, rasH oncogene activation and additional chromosome loss. Oncogene (1995) 0.90
Differential stromal regulation of MMP-1 expression in benign and malignant keratinocytes. J Invest Dermatol (2001) 0.90
5-Lipoxygenase expression in Langerhans cells of normal human epidermis. Proc Natl Acad Sci U S A (1998) 0.90
Progressive abrogation of TGF-beta 1 and EGF growth control is associated with tumour progression in ras-transfected human keratinocytes. Int J Cancer (1992) 0.90
Angiogenic switch occurs late in squamous cell carcinomas of human skin. Br J Cancer (2000) 0.88
Migration of a human keratinocyte cell line (HACAT) to interstitial collagen type I is mediated by the alpha 2 beta 1-integrin receptor. J Invest Dermatol (1992) 0.88
12-O-tetradecanoylphorbol-13-acetate induces clonal expansion of potentially malignant keratinocytes in a tissue model of early neoplastic progression. Cancer Res (1999) 0.88
Establishment of oral mucosa phenotype in vitro in correlation to epithelial anchorage. Cell Tissue Res (1998) 0.87
Expression and function of connexin in normal and transformed human keratinocytes in culture. Carcinogenesis (1994) 0.87
Tumor induction in initiated mouse skin by phorbol esters and methyl methanesulfonate: correlation between chromosomal damage and conversion ('stage I of tumor promotion') in vivo. Carcinogenesis (1989) 0.86
DNA excision repair in ultraviolet-irradiated normal and malignantly transformed mouse epidermal cell cultures. Cancer Res (1977) 0.86
Binding of epidermal growth factor to primary and permanent cultures of mouse epidermal cells: inhibition by tumor-promoting phorbol esters. Cancer Lett (1979) 0.86
Expression and modification of keratins during terminal differentiation of mammalian epidermis. Curr Top Dev Biol (1987) 0.86
Correlation of prekaratin peptides and ultrastructure in epithelial cells of human skin tumors in vivo and in vitro. Anticancer Res (1981) 0.85
Inhibition of collagenase-3 (MMP-13) expression in transformed human keratinocytes by interferon-gamma is associated with activation of extracellular signal-regulated kinase-1,2 and STAT1. Oncogene (2000) 0.85
Functional evidence for tumor-suppressor activity on chromosome 15 in human skin carcinoma cells and thrombospondin-1 as the potential suppressor. J Cell Physiol (1997) 0.85
The amido black assay: a simple and quantitative multipurpose test of adhesion, proliferation, and cytotoxicity in microplate cultures of keratinocytes (HaCaT) and other cell types growing adherently or in suspension. J Immunol Methods (1994) 0.84
Paracrine factor and cell-cell contact-mediated induction of protease and c-ets gene expression in malignant keratinocyte/dermal fibroblast cocultures. Exp Cell Res (1994) 0.84
A rapid procedure for flow cytometric DNA analysis in cultures of normal and transformed epidermal cells. J Invest Dermatol (1988) 0.83
Basement membrane formation by malignant mouse keratinocyte cell lines in organotypic culture and transplants: correlation with degree of morphologic differentiation. J Cancer Res Clin Oncol (1987) 0.83
Defects of basement membrane and hemidesmosome structure correlate with malignant phenotype and stromal interactions in HaCaT-Ras xenografts. Differentiation (1999) 0.83
Magnetic resonance imaging of nude mice with heterotransplanted high-grade squamous cell carcinomas: use of a low-loaded, covalently bound Gd-Hsa conjugate as contrast agent with high tumor affinity. Invest Radiol (2002) 0.83
Restoration of the epidermal phenotype by follicular outer root sheath cells in recombinant culture with dermal fibroblasts. Exp Cell Res (1991) 0.82
Organotypic and epidermal-dermal co-cultures of normal human keratinocytes and dermal cells: Regulation of transforming growth factor alpha, beta1 and beta2 mRNA levels. Toxicol In Vitro (1994) 0.82
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Tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate enhances sister chromatid exchanges and numerical and structural chromosome aberrations in primary mouse epidermal cell cultures. Cancer Lett (1982) 0.82
Fibroblast-directed expression and localization of 92-kDa type IV collagenase along the tumor-stroma interface in an in vitro three-dimensional model of human squamous cell carcinoma. Mol Carcinog (1997) 0.82
Isolation and cultivation of epidermal cells from embryonic mouse skin. Naturwissenschaften (1971) 0.81
Matrix metalloproteinases-2,-3,-7,-9 and-10, but not MMP-11, are differentially expressed in normal, benign tumorigenic and malignant human keratinocyte cell lines. Biol Chem (2000) 0.81
Outer root sheath (ORS) cells organize into epidermoid cyst-like spheroids when cultured inside Matrigel: a light-microscopic and immunohistological comparison between human ORS cells and interfollicular keratinocytes. Cell Tissue Res (1994) 0.81
In vitro transformation and tumor progression. Recent Results Cancer Res (1993) 0.81
Phenotypic modulation of human hair matrix cells (trichocytes) by environmental influence in vitro and in vivo. Epithelial Cell Biol (1993) 0.80
5-lipoxygenase expression in cultured human keratinocytes. Adv Prostaglandin Thromboxane Leukot Res (1995) 0.80
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Experimental modulation of the differentiated phenotype of keratinocytes from epidermis and hair follicle outer root sheath and matrix cells. Ann N Y Acad Sci (1991) 0.79
Postreplication repair of DNA in ultraviolet light-irradiated normal and malignancy transformed mouse epidermal cell cultures. Cancer Res (1978) 0.79
Association of deficient DNA repair during G2 phase with progression from benign to malignant state in a line of human skin keratinocytes transfected with ras oncogene. Carcinogenesis (1994) 0.79