Biogenesis and regulation of the Vibrio cholerae toxin-coregulated pilus: analogies to other virulence factor secretory systems.

PubWeight™: 1.43‹?› | Rank: Top 5%

🔗 View Article (PMID 8097177)

Published in Gene on April 15, 1993

Authors

M R Kaufman1, C E Shaw, I D Jones, R K Taylor

Author Affiliations

1: Department of Microbiology and Immunology, University of Tennessee, Memphis 38163.

Articles citing this

Cholera. Clin Microbiol Rev (1995) 12.33

Arac/XylS family of transcriptional regulators. Microbiol Mol Biol Rev (1997) 6.56

Type II secretion and pathogenesis. Infect Immun (2001) 2.75

General secretion pathway (eps) genes required for toxin secretion and outer membrane biogenesis in Vibrio cholerae. J Bacteriol (1997) 2.69

Differential expression of the ToxR regulon in classical and E1 Tor biotypes of Vibrio cholerae is due to biotype-specific control over toxT expression. Proc Natl Acad Sci U S A (1996) 2.17

Enteropathogenic Escherichia coli: identification of a gene cluster coding for bundle-forming pilus morphogenesis. J Bacteriol (1996) 2.08

Type IV pili: paradoxes in form and function. Curr Opin Struct Biol (2008) 2.03

The Vibrio cholerae toxin-coregulated-pilus gene tcpI encodes a homolog of methyl-accepting chemotaxis proteins. Infect Immun (1994) 1.75

Analysis of an autoregulatory loop controlling ToxT, cholera toxin, and toxin-coregulated pilus production in Vibrio cholerae. J Bacteriol (1999) 1.57

Direct interaction of the EpsL and EpsM proteins of the general secretion apparatus in Vibrio cholerae. J Bacteriol (1999) 1.40

Differential transcription of the tcpPH operon confers biotype-specific control of the Vibrio cholerae ToxR virulence regulon. Infect Immun (1999) 1.29

Vibrio cholerae ToxT independently activates the divergently transcribed aldA and tagA genes. J Bacteriol (2005) 1.21

BfpB, an outer membrane lipoprotein required for the biogenesis of bundle-forming pili in enteropathogenic Escherichia coli. J Bacteriol (1996) 1.20

A molecular switch controlling competence and motility: competence regulatory factors ComS, MecA, and ComK control sigmaD-dependent gene expression in Bacillus subtilis. J Bacteriol (1998) 1.13

Genes required for plasmid R64 thin-pilus biogenesis: identification and localization of products of the pilK, pilM, pilO, pilP, pilR, and pilT genes. J Bacteriol (2002) 1.13

Physical linkage of the Vibrio cholerae mannose-sensitive hemagglutinin secretory and structural subunit gene loci: identification of the mshG coding sequence. Infect Immun (1996) 1.12

Novel topology of BfpE, a cytoplasmic membrane protein required for type IV fimbrial biogenesis in enteropathogenic Escherichia coli. J Bacteriol (2001) 1.09

Molecular characterization of a new variant of toxin-coregulated pilus protein (TcpA) in a toxigenic non-O1/Non-O139 strain of Vibrio cholerae. Infect Immun (2000) 1.08

Type IV prepilin peptidase gene of Neisseria gonorrhoeae MS11: presence of a related gene in other piliated and nonpiliated Neisseria strains. J Bacteriol (1994) 0.99

Membrane association and multimerization of TcpT, the cognate ATPase ortholog of the Vibrio cholerae toxin-coregulated-pilus biogenesis apparatus. J Bacteriol (2007) 0.97

Haitian variant tcpA in Vibrio cholerae O1 El Tor strains in Kolkata, India. J Clin Microbiol (2013) 0.91

Outer membrane translocation arrest of the TcpA pilin subunit in rfb mutants of Vibrio cholerae O1 strain 569B. J Bacteriol (1997) 0.91

Vibrio cholerae VexH encodes a multiple drug efflux pump that contributes to the production of cholera toxin and the toxin co-regulated pilus. PLoS One (2012) 0.89

Secretion of TcpF by the Vibrio cholerae toxin-coregulated pilus biogenesis apparatus requires an N-terminal determinant. J Bacteriol (2013) 0.76

The Vibrio cholerae Minor Pilin TcpB Initiates Assembly and Retraction of the Toxin-Coregulated Pilus. PLoS Pathog (2016) 0.75

Articles by these authors

(truncated to the top 100)

Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin. Proc Natl Acad Sci U S A (1987) 15.50

Cholera toxin transcriptional activator toxR is a transmembrane DNA binding protein. Cell (1987) 11.04

Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans. J Exp Med (1988) 9.19

Positive selection vectors for allelic exchange. Gene (1996) 5.97

Characteristics of Lactic Acid Bacteria from Commercial Cucumber Fermentations. J Bacteriol (1946) 4.61

Toxin-coregulated pilus, but not mannose-sensitive hemagglutinin, is required for colonization by Vibrio cholerae O1 El Tor biotype and O139 strains. Infect Immun (1996) 4.06

Production of diagnostic pigment by phenoloxidase activity of cryptococcus neoformans. Appl Microbiol (1972) 3.86

Characterization of a periplasmic thiol:disulfide interchange protein required for the functional maturation of secreted virulence factors of Vibrio cholerae. Proc Natl Acad Sci U S A (1992) 3.12

Control of the ToxR virulence regulon in Vibrio cholerae by environmental stimuli. Mol Microbiol (1997) 3.11

Procedure for Bacteriological Examination of Brined, Salted and Pickled Vegetables and Vegetable Products. Am J Public Health Nations Health (1946) 2.83

Isolation and characterization of chain-terminating nonsense mutations in a porin regulator gene, envZ. J Bacteriol (1983) 2.61

Cyclic AMP and its receptor protein negatively regulate the coordinate expression of cholera toxin and toxin-coregulated pilus in Vibrio cholerae. Proc Natl Acad Sci U S A (1997) 2.58

Delineation of pilin domains required for bacterial association into microcolonies and intestinal colonization by Vibrio cholerae. Mol Microbiol (2000) 2.55

Identification of OmpR: a positive regulatory protein controlling expression of the major outer membrane matrix porin proteins of Escherichia coli K-12. J Bacteriol (1981) 2.36

Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study. Neurobiol Dis (2004) 2.29

Flail arm syndrome: a distinctive variant of amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry (1998) 2.28

TcpA pilin sequences and colonization requirements for O1 and O139 vibrio cholerae. Mol Microbiol (1994) 2.25

A new level in the Vibrio cholerae ToxR virulence cascade: AphA is required for transcriptional activation of the tcpPH operon. Mol Microbiol (1999) 2.23

The mannose-sensitive hemagglutinin of Vibrio cholerae promotes adherence to zooplankton. Appl Environ Microbiol (2001) 2.23

Differential expression of the ToxR regulon in classical and E1 Tor biotypes of Vibrio cholerae is due to biotype-specific control over toxT expression. Proc Natl Acad Sci U S A (1996) 2.17

An estimate of amyotrophic lateral sclerosis heritability using twin data. J Neurol Neurosurg Psychiatry (2010) 2.14

Single amino acid substitutions in the N-terminus of Vibrio cholerae TcpA affect colonization, autoagglutination, and serum resistance. Mol Microbiol (1995) 2.03

Isolation and characterization of delta ompB strains of Escherichia coli by a general method based on gene fusions. J Bacteriol (1985) 1.99

Proteome-based plasma biomarkers for Alzheimer's disease. Brain (2006) 1.98

Isolation and characterization of mutations altering expression of the major outer membrane porin proteins using the local anaesthetic procaine. J Mol Biol (1983) 1.97

Antibodies directed against the toxin-coregulated pilus isolated from Vibrio cholerae provide protection in the infant mouse experimental cholera model. J Infect Dis (1990) 1.97

Vibrio cholerae H-NS silences virulence gene expression at multiple steps in the ToxR regulatory cascade. J Bacteriol (2000) 1.92

Localization of protective epitopes within the pilin subunit of the Vibrio cholerae toxin-coregulated pilus. Infect Immun (1991) 1.90

Investigation of the roles of toxin-coregulated pili and mannose-sensitive hemagglutinin pili in the pathogenesis of Vibrio cholerae O139 infection. Infect Immun (1998) 1.90

Organization of tcp, acf, and toxT genes within a ToxT-dependent operon. Mol Microbiol (1995) 1.87

Prognostic modelling of therapeutic interventions in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord (2002) 1.80

Water intoxication: a possible complication during endurance exercise. Med Sci Sports Exerc (1985) 1.79

New VAPB deletion variant and exclusion of VAPB mutations in familial ALS. Neurology (2008) 1.76

Natural history and clinical features of the flail arm and flail leg ALS variants. Neurology (2009) 1.71

Vibrio cholerae O395 tcpA pilin gene sequence and comparison of predicted protein structural features to those of type 4 pilins. Infect Immun (1990) 1.68

A large-scale international meta-analysis of paraoxonase gene polymorphisms in sporadic ALS. Neurology (2009) 1.67

Identification of the Vibrio cholerae type 4 prepilin peptidase required for cholera toxin secretion and pilus formation. Mol Microbiol (1998) 1.59

Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis. Hum Mol Genet (1999) 1.54

Amyotrophic lateral sclerosis in South-East England: a population-based study. The South-East England register for amyotrophic lateral sclerosis (SEALS Registry). Neuroepidemiology (2007) 1.52

Phylogenetic relationships among global populations of Pseudomonas syringae pv. actinidiae. Phytopathology (2012) 1.52

Processing of TCP pilin by TcpJ typifies a common step intrinsic to a newly recognized pathway of extracellular protein secretion by gram-negative bacteria. Genes Dev (1991) 1.40

The type 4 prepilin peptidases comprise a novel family of aspartic acid proteases. J Biol Chem (2000) 1.40

Immunogenicity of Vibrio cholerae O1 toxin-coregulated pili in experimental and clinical cholera. Infect Immun (1991) 1.39

Mutations that define the promoter of ompF, a gene specifying a major outer membrane porin protein. J Bacteriol (1985) 1.38

Cell culture compared with broth for detection of Trichomonas vaginalis. J Clin Microbiol (1987) 1.36

Glutamate slows axonal transport of neurofilaments in transfected neurons. J Cell Biol (2000) 1.33

Prolonged survival in motor neuron disease: a descriptive study of the King's database 1990-2002. J Neurol Neurosurg Psychiatry (2003) 1.33

Genetic footprint on the ToxR-binding site in the promoter for cholera toxin. Mol Microbiol (1996) 1.31

Mills' and other isolated upper motor neurone syndromes: in vivo study with 11C-(R)-PK11195 PET. J Neurol Neurosurg Psychiatry (2005) 1.29

Genetic and transcriptional analyses of the Vibrio cholerae mannose-sensitive hemagglutinin type 4 pilus gene locus. J Bacteriol (1999) 1.29

Differential transcription of the tcpPH operon confers biotype-specific control of the Vibrio cholerae ToxR virulence regulon. Infect Immun (1999) 1.29

Mutational analysis reveals the FUS homolog TAF15 as a candidate gene for familial amyotrophic lateral sclerosis. Am J Med Genet B Neuropsychiatr Genet (2011) 1.26

Distinct cerebral lesions in sporadic and 'D90A' SOD1 ALS: studies with [11C]flumazenil PET. Brain (2005) 1.24

In vitro activity of Ro 15-8074, Ro 19-5247, A-56268, and roxithromycin (RU 28965) against Neisseria gonorrhoeae and Chlamydia trachomatis. Antimicrob Agents Chemother (1987) 1.23

Endothelial vasodilator production by uterine and systemic arteries. II. Pregnancy effects on NO synthase expression. Am J Physiol (1997) 1.19

Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS. J Neurol Neurosurg Psychiatry (2005) 1.16

Structure of TcpG, the DsbA protein folding catalyst from Vibrio cholerae. J Mol Biol (1997) 1.16

In vitro activity of difloxacin hydrochloride (A-56619), A-56620, and cefixime (CL 284,635; FK 027) against selected genital pathogens. Antimicrob Agents Chemother (1986) 1.16

Association of apolipoprotein E epsilon 4 allele with bulbar-onset motor neuron disease. Lancet (1996) 1.13

Physical linkage of the Vibrio cholerae mannose-sensitive hemagglutinin secretory and structural subunit gene loci: identification of the mshG coding sequence. Infect Immun (1996) 1.12

Phosphorylation of neurofilament heavy chain side-arms by stress activated protein kinase-1b/Jun N-terminal kinase-3. J Cell Sci (2000) 1.10

Selection for mutants altered in the expression or export of outer membrane porin OmpF. J Bacteriol (1985) 1.08

Genetic analysis of 987P adhesion and fimbriation of Escherichia coli: the fas genes link both phenotypes. J Bacteriol (1991) 1.07

Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology. Neuroscience (2010) 1.06

In-vitro susceptibility of 400 isolates of Neisseria gonorrhoeae in Vancouver, 1982-84. CMAJ (1986) 1.06

Cloning and sequencing of a gene encoding the 69-kDa extracellular chitinase of Janthinobacterium lividum. FEMS Microbiol Lett (1995) 1.05

Domains within the Vibrio cholerae toxin coregulated pilin subunit that mediate bacterial colonization. Gene (1997) 1.02

The Vibrio cholerae mannose-sensitive hemagglutinin is the receptor for a filamentous bacteriophage from V. cholerae O139. Infect Immun (1998) 1.02

Identification of a pilus colonization factor that is coordinately regulated with cholera toxin. Ann Sclavo Collana Monogr (1986) 1.02

Endothelial vasodilator production by uterine and systemic arteries. VII. Estrogen and progesterone effects on eNOS. Am J Physiol Heart Circ Physiol (2001) 1.01

SOD1 and cognitive dysfunction in familial amyotrophic lateral sclerosis. J Neurol (2009) 1.00

Shared antigenicity and immunogenicity of type 4 pilins expressed by Pseudomonas aeruginosa, Moraxella bovis, Neisseria gonorrhoaea, Dichelobacter nodosus, and Vibrio cholerae. Infect Immun (1991) 1.00

Mutations in toxR and toxS that separate transcriptional activation from DNA binding at the cholera toxin gene promoter. J Bacteriol (1998) 0.99

Molecular and morphological reassessment of relationships within the Vittadinia group of Astereae (Asteraceae). Am J Bot (2001) 0.99

987P fimbrial gene identification and protein characterization by T7 RNA polymerase-induced transcription and TnphoA mutagenesis. Mol Microbiol (1991) 0.98

Rapid presumptive identification of Gardnerella vaginalis (Haemophilus vaginalis) from human blood agar media. J Clin Microbiol (1981) 0.98

Endothelial vasodilator production by uterine and systemic arteries. III. Ovarian and estrogen effects on NO synthase. Am J Physiol (1998) 0.98

The 987P fimbrial gene cluster of enterotoxigenic Escherichia coli is plasmid encoded. Infect Immun (1990) 0.96

Identification of bacterial cell-surface virulence determinants with TnphoA. Methods Enzymol (1994) 0.95

p35/cdk5 binds and phosphorylates beta-catenin and regulates beta-catenin/presenilin-1 interaction. Eur J Neurosci (2001) 0.95

Physical determinants of independence in mature women. Arch Phys Med Rehabil (1995) 0.95

Evaluation of cholera vaccines formulated with toxin-coregulated pilin peptide plus polymer adjuvant in mice. Infect Immun (2001) 0.93

Expression of the Fe65 adapter protein in adult and developing mouse brain. Neuroscience (2002) 0.91

Virus on virus infects bacterium. Nature (1999) 0.91

Intron 7 retention and exon 9 skipping EAAT2 mRNA variants are not associated with amyotrophic lateral sclerosis. Ann Neurol (2001) 0.90

Four novel SPG3A/atlastin mutations identified in autosomal dominant hereditary spastic paraplegia kindreds with intra-familial variability in age of onset and complex phenotype. Clin Genet (2009) 0.89

Chloroquine-resistant malaria. S Afr Med J (1983) 0.89

[11C]-WAY100635 PET demonstrates marked 5-HT1A receptor changes in sporadic ALS. Brain (2005) 0.88

Peroxidase in human cervical mucus during the menstrual cycle. Contraception (1975) 0.88

Endothelium-derived nitric oxide synthase protein expression in ovine placental arteries. Biol Reprod (2001) 0.87

Immune response genes modulate serologic responses to Vibrio cholerae TcpA pilin peptides. Infect Immun (2001) 0.87

Sequence and functional analysis of the gene encoding Vibrio cholerae cAMP receptor protein. Gene (1997) 0.86

Flow-mediated vasodilation measurements in Cavalier King Charles Spaniels with increasing severity of myxomatous mitral valve disease. J Vet Intern Med (2011) 0.84

Anti-class II monoclonal antibody-targeted Vibrio cholerae TcpA pilin: modulation of serologic response, epitope specificity, and isotype. Infect Immun (2001) 0.83

Tau levels do not influence human ALS or motor neuron degeneration in the SOD1G93A mouse. Neurology (2010) 0.81

CHMP2B mutations are not a common cause of familial or sporadic amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry (2008) 0.80

Experimental formation of zinc and copper complexes of chlorophyll derivatives in vegetable tissue by thermal processing. J Agric Food Chem (1977) 0.80

Androgen induced cell death in SHSY5Y neuroblastoma cells expressing wild-type and spinal bulbar muscular atrophy mutant androgen receptors. Biochim Biophys Acta (2001) 0.79

Transportin 1 colocalization with Fused in Sarcoma (FUS) inclusions is not characteristic for amyotrophic lateral sclerosis-FUS confirming disrupted nuclear import of mutant FUS and distinguishing it from frontotemporal lobar degeneration with FUS inclusions. Neuropathol Appl Neurobiol (2013) 0.78

No association of the SOD1 locus and disease susceptibility or phenotype in sporadic ALS. Neurology (2004) 0.78