Published in J Biol Chem on April 01, 1994
Real-time evaluation of myosin light chain kinase activation in smooth muscle tissues from a transgenic calmodulin-biosensor mouse. Proc Natl Acad Sci U S A (2004) 1.88
Inhibition of Rho-associated kinase blocks agonist-induced Ca2+ sensitization of myosin phosphorylation and force in guinea-pig ileum. J Physiol (2000) 1.71
Calcium-sensitive MRI contrast agents based on superparamagnetic iron oxide nanoparticles and calmodulin. Proc Natl Acad Sci U S A (2006) 1.63
Calmodulin mediates differential sensitivity of CaMKII and calcineurin to local Ca2+ in cardiac myocytes. Biophys J (2008) 1.61
Gap junction channels exhibit connexin-specific permeability to cyclic nucleotides. J Gen Physiol (2008) 1.35
Myosin regulatory light chain phosphorylation attenuates cardiac hypertrophy. J Biol Chem (2008) 1.23
Signaling processes for initiating smooth muscle contraction upon neural stimulation. J Biol Chem (2009) 1.23
Free and bound intracellular calmodulin measurements in cardiac myocytes. Cell Calcium (2006) 1.21
Diffusional mobility of parvalbumin in spiny dendrites of cerebellar Purkinje neurons quantified by fluorescence recovery after photobleaching. Biophys J (2003) 1.17
Effect of metabolic inhibition on intracellular Ca2+, phosphorylation of myosin regulatory light chain and force in rat smooth muscle. J Physiol (1997) 1.15
Activation by Ca2+/calmodulin of an exogenous myosin light chain kinase in mouse arteries. J Physiol (2009) 1.08
Biochemistry of smooth muscle myosin light chain kinase. Arch Biochem Biophys (2011) 1.06
Differential integration of Ca2+-calmodulin signal in intact ventricular myocytes at low and high affinity Ca2+-calmodulin targets. J Biol Chem (2008) 1.06
A signal transduction pathway model prototype I: From agonist to cellular endpoint. Biophys J (2004) 1.00
Signaling through myosin light chain kinase in smooth muscles. J Biol Chem (2013) 0.98
The pivotal role of airway smooth muscle in asthma pathophysiology. J Allergy (Cairo) (2011) 0.98
Tracer diffusion through F-actin: effect of filament length and cross-linking. Biophys J (1996) 0.96
Rational design of new binding specificity by simultaneous mutagenesis of calmodulin and a target peptide. Biochemistry (2006) 0.96
Myosin light chain kinase binding to a unique site on F-actin revealed by three-dimensional image reconstruction. J Cell Biol (2001) 0.92
Characterization of tightly associated smooth muscle myosin-myosin light-chain kinase-calmodulin complexes. J Mol Biol (2009) 0.88
Myosin light chain kinase (MLCK) regulates cell migration in a myosin regulatory light chain phosphorylation-independent mechanism. J Biol Chem (2014) 0.86
Maximal stimulation-induced in situ myosin light chain kinase activity is upregulated in fetal compared with adult ovine carotid arteries. Am J Physiol Heart Circ Physiol (2008) 0.85
The importance of Rho-associated kinase-induced Ca2+ sensitization as a component of electromechanical and pharmacomechanical coupling in rat ureteric smooth muscle. Cell Calcium (2011) 0.85
A signal transduction pathway model prototype II: Application to Ca2+-calmodulin signaling and myosin light chain phosphorylation. Biophys J (2004) 0.84
A mathematical model of T lymphocyte calcium dynamics derived from single transmembrane protein properties. Front Immunol (2013) 0.82
Differential control of calcium homeostasis and vascular reactivity by Ca2+/calmodulin-dependent kinase II. Hypertension (2013) 0.81
Regulation of myosin light chain kinase during insulin-stimulated glucose uptake in 3T3-L1 adipocytes. PLoS One (2013) 0.81
Constitutive phosphorylation of myosin phosphatase targeting subunit-1 in smooth muscle. J Physiol (2014) 0.80
Gelsolin and non-muscle myosin IIA interact to mediate calcium-regulated collagen phagocytosis. J Biol Chem (2011) 0.78
Kinetics of myosin light chain kinase activation of smooth muscle myosin in an in vitro model system. Biochemistry (2013) 0.77
Differentiation of Human Adipose Derived Stem Cells into Smooth Muscle Cells Is Modulated by CaMKIIγ. Stem Cells Int (2016) 0.75
Kinetics of contraction in depolarized smooth muscle from guinea-pig taenia coli after photodestruction of nifedipine. J Physiol (1999) 0.75
Role of various kinases in muscarinic M3 receptor-mediated contraction of longitudinal muscle of rat colon. J Smooth Muscle Res (2014) 0.75
Role of CaMKII in Ang-II-dependent small artery remodeling. Vascul Pharmacol (2016) 0.75
Hindered diffusion of inert tracer particles in the cytoplasm of mouse 3T3 cells. Proc Natl Acad Sci U S A (1987) 5.19
Probing the structure of cytoplasm. J Cell Biol (1986) 5.10
The function of myosin and myosin light chain kinase phosphorylation in smooth muscle. Annu Rev Pharmacol Toxicol (1985) 4.80
Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav. Science (1998) 4.41
Dedicated myosin light chain kinases with diverse cellular functions. J Biol Chem (2000) 3.89
Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3. Curr Biol (2000) 3.75
Impaired metabolic modulation of alpha-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle. Proc Natl Acad Sci U S A (1998) 3.00
Myosin light chain phosphorylation in vertebrate striated muscle: regulation and function. Am J Physiol (1993) 2.81
Functional muscle ischemia in neuronal nitric oxide synthase-deficient skeletal muscle of children with Duchenne muscular dystrophy. Proc Natl Acad Sci U S A (2000) 2.49
Tracer diffusion in F-actin and Ficoll mixtures. Toward a model for cytoplasm. Biophys J (1990) 2.17
Neuronal nitric oxide synthase and dystrophin-deficient muscular dystrophy. Proc Natl Acad Sci U S A (1996) 2.06
Role for alpha-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies. Nat Cell Biol (1999) 2.01
Regulation of smooth muscle contractile elements by second messengers. Annu Rev Physiol (1989) 1.98
The effect of myosin phosphorylation on the contractile properties of skinned rabbit skeletal muscle fibers. J Biol Chem (1985) 1.95
Alteration of cross-bridge kinetics by myosin light chain phosphorylation in rabbit skeletal muscle: implications for regulation of actin-myosin interaction. Proc Natl Acad Sci U S A (1990) 1.87
Myosin light chain phosphorylation affects the structure of rabbit skeletal muscle thick filaments. Biophys J (1996) 1.75
Measurement of cyclic 3',5'-denosine monophosphate by the activation of skeletal muscle protein kinase. J Biol Chem (1971) 1.72
Phosphorylation of the inhibitor component of troponin by phosphorylase kinase. J Biol Chem (1972) 1.71
Charge replacement near the phosphorylatable serine of the myosin regulatory light chain mimics aspects of phosphorylation. Proc Natl Acad Sci U S A (1994) 1.67
Myosin light chain kinases. J Muscle Res Cell Motil (1997) 1.67
Phosphorylation of myosin in permeabilized mammalian cardiac and skeletal muscle cells. Am J Physiol (1986) 1.66
Molecular characterization of a mammalian smooth muscle myosin light chain kinase. J Biol Chem (1991) 1.59
Viscoelastic response of fibroblasts to tension transmitted through adherens junctions. Biophys J (1997) 1.57
nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle. Physiol Genomics (2000) 1.54
Familial hypertrophic cardiomyopathy mutations in the regulatory light chains of myosin affect their structure, Ca2+ binding, and phosphorylation. J Biol Chem (2000) 1.50
Molecular mechanisms of beta-adrenergic relaxation of airway smooth muscle. Annu Rev Physiol (1996) 1.49
The amino acid sequences of the phosphorylated sites in troponin-I from rabbit skeletal muscle. FEBS Lett (1974) 1.49
Mechanical loading regulates NOS expression and activity in developing and adult skeletal muscle. Am J Physiol (1998) 1.46
Mechanism and size cutoff for steric exclusion from actin-rich cytoplasmic domains. Biophys J (1996) 1.44
Activation of skeletal muscle myosin light chain kinase by calcium(2+) and calmodulin. Biochemistry (1980) 1.43
Cytoarchitecture of size-excluding compartments in living cells. J Cell Sci (1993) 1.42
Phosphorylation of cardiac troponin by cyclic adenosine 3':5'-monophosphate-dependent protein kinase. J Biol Chem (1977) 1.41
Structures of calmodulin and a functional myosin light chain kinase in the activated complex: a neutron scattering study. Biochemistry (1997) 1.41
Behavior of a fluorescent analogue of calmodulin in living 3T3 cells. J Cell Biol (1985) 1.39
Myosin light chain kinase phosphorylation in tracheal smooth muscle. J Biol Chem (1990) 1.37
Activation of four enzymes by two series of calmodulin mutants with point mutations in individual Ca2+ binding sites. J Biol Chem (1993) 1.35
Structure and regulation of calcium/calmodulin-dependent protein kinases. Chem Rev (2001) 1.35
Ca2+, cAMP, and changes in myosin phosphorylation during contraction of smooth muscle. Am J Physiol (1983) 1.31
Myosin light chain phosphorylation in fast and slow skeletal muscles in situ. Am J Physiol (1984) 1.31
Different phosphorylated forms of myosin in contracting tracheal smooth muscle. J Biol Chem (1986) 1.30
GTP gamma S-dependent regulation of smooth muscle contractile elements. Am J Physiol (1992) 1.29
Localization and activity of myosin light chain kinase isoforms during the cell cycle. J Cell Biol (2000) 1.29
Measurement of chemical phosphate in proteins. Methods Enzymol (1983) 1.29
Brownian motion of inert tracer macromolecules in polymerized and spontaneously bundled mixtures of actin and filamin. J Cell Biol (1990) 1.28
Myosin light chain phosphorylation and phosphorylase A activity in rat extensor digitorum longus muscle. Biochem Biophys Res Commun (1979) 1.27
Activation of smooth muscle contraction: relation between myosin phosphorylation and stiffness. Science (1986) 1.27
Sites phosphorylated in myosin light chain in contracting smooth muscle. J Biol Chem (1988) 1.27
Nitric oxide contributes to vascular smooth muscle relaxation in contracting fast-twitch muscles. Physiol Genomics (2001) 1.25
Phosphorylation of myosin in perfused rabbit and rat hearts. Am J Physiol (1980) 1.25
Skeletal muscle contractions stimulate cGMP formation and attenuate vascular smooth muscle myosin phosphorylation via nitric oxide. FEBS Lett (1998) 1.23
Phosphorylation of myosin light chain kinase by the multifunctional calmodulin-dependent protein kinase II in smooth muscle cells. J Biol Chem (1992) 1.20
Myosin light chain phosphorylation-dephosphorylation in mammalian skeletal muscle. Am J Physiol (1982) 1.18
Frequency-dependent myosin light chain phosphorylation in isolated myocardium. J Mol Cell Cardiol (1986) 1.17
Myosin phosphorylation, force, and maximal shortening velocity in neurally stimulated tracheal smooth muscle. Am J Physiol (1985) 1.16
Effects of pH, ionic strength, and temperature on activation by calmodulin an catalytic activity of myosin light chain kinase. Biochemistry (1982) 1.15
Identification of a novel actin binding motif in smooth muscle myosin light chain kinase. J Biol Chem (1999) 1.13
Contractile elements and myosin light chain phosphorylation in myometrial tissue from nonpregnant and pregnant women. J Clin Invest (1993) 1.12
Structural and functional responses of mammalian thick filaments to alterations in myosin regulatory light chains. J Struct Biol (1998) 1.12
Role of Ca2+ and myosin light chain phosphorylation in regulation of smooth muscle. Am J Physiol (1982) 1.11
Phosphorylation of smooth muscle myosin heavy and light chains. Effects of phorbol dibutyrate and agonists. J Biol Chem (1989) 1.07
Properties of filament-bound myosin light chain kinase. J Biol Chem (1999) 1.07
Substrate specificity of myosin light chain kinases. J Biol Chem (1992) 1.07
Domain characterization of rabbit skeletal muscle myosin light chain kinase. J Biol Chem (1990) 1.06
Calcium dependence of myosin light chain phosphorylation in smooth muscle cells. J Biol Chem (1988) 1.06
Activation properties of myosin light chain kinase during contraction/relaxation cycles of tonic and phasic smooth muscles. J Biol Chem (1994) 1.06
Selective immunocytochemical detection of fluorescent analogs with antibodies specific for the fluorophore. Cell Motil (1984) 1.05
Regulation of phosphorylase activation in skeletal muscle in vivo. J Biol Chem (1971) 1.05
Binding of myosin light chain kinase to cellular actin-myosin filaments. J Biol Chem (1997) 1.03
Phosphorylation of skeletal muscle contractile proteins in vivo. Biochem Biophys Res Commun (1977) 1.03
The control of pigment migration in isolated erythrophores of Holocentrus ascensionis (Osbeck). II. The role of calcium. Cell (1982) 1.03
A molecular mechanism for autoinhibition of myosin light chain kinases. J Biol Chem (1993) 1.03
Phosphorylation of contractile proteins in relation to muscle function. Adv Cyclic Nucleotide Res (1980) 1.02
Changes in interfilament spacing mimic the effects of myosin regulatory light chain phosphorylation in rabbit psoas fibers. J Struct Biol (1998) 1.02
Phosphorylation-dependent structural changes in the regulatory light chain domain of smooth muscle heavy meromyosin. J Biol Chem (1999) 1.01
Phosphorylation of myosin light chain kinase: a cellular mechanism for Ca2+ desensitization. Mol Cell Biochem (1993) 1.01
Vascular smooth muscle contractile elements. Cellular regulation. Hypertension (1991) 1.01
Myosin phosphorylation in smooth and skeletal muscles: regulation and function. Prog Clin Biol Res (1990) 1.01
Gap junction communication modulates [Ca2+]i oscillations and enzyme secretion in pancreatic acini. J Biol Chem (1993) 1.00
Interference with lysosomal proteolysis fails to reduce cardiac myosin degradation. Biochem Biophys Res Commun (1980) 1.00
Functional and molecular adaptations in skeletal muscle of myoglobin-mutant mice. Am J Physiol Cell Physiol (2001) 0.99
Okadaic acid uncouples myosin light chain phosphorylation and tension in smooth muscle. FEBS Lett (1990) 0.99
Genetically engineered calmodulins differentially activate target enzymes. J Biol Chem (1986) 0.98
Regulation of myosin light chain and phosphorylase phosphorylation in tracheal smooth muscle. J Biol Chem (1982) 0.98
Myosin phosphorylation during contraction and relaxation of tracheal smooth muscle. J Biol Chem (1980) 0.98