Published in Transplantation on September 01, 1993
Current advances and travails in islet transplantation. Diabetes (2009) 1.63
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Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med (2000) 18.26
Hepatitis C virus replication in mice with chimeric human livers. Nat Med (2001) 5.87
Islet isolation assessment in man and large animals. Acta Diabetol Lat (1991) 2.89
Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes (2001) 2.51
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Serine-protease inhibition during islet isolation increases islet yield from human pancreases with prolonged ischemia. Transplantation (2001) 1.54
Glucose-dependent insulin release from genetically engineered K cells. Science (2000) 1.52
Impaired proinsulin processing is a characteristic of transplanted islets. Am J Transplant (2009) 1.48
Large scale isolation, growth, and function of porcine neonatal islet cells. J Clin Invest (1996) 1.46
Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts. Proc Natl Acad Sci U S A (2010) 1.45
Insulin-stimulated insulin secretion in single pancreatic beta cells. J Biol Chem (1999) 1.44
Cytotoxic effects of cytokines on human pancreatic islet cells in monolayer culture. J Clin Endocrinol Metab (1990) 1.44
Variables in organ donors that affect the recovery of human islets of Langerhans. Transplantation (1996) 1.33
Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion. Cell Transplant (1999) 1.31
Revelation of specificity of 64K autoantibodies in IDDM serums by high-resolution 2-D gel electrophoresis. Unambiguous identification of 64K target antigen. Diabetes (1989) 1.30
Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates allows long-term graft survival without systemic immunosuppression. Diabetes (1997) 1.29
Left paraduodenal hernia: an unusual cause of small-bowel obstruction. Can J Surg (2001) 1.29
Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction. Diabetes (1999) 1.25
Immunohistochemical characterisation of cells co-producing insulin and glucagon in the developing human pancreas. Diabetologia (2011) 1.23
A brief history of endoscopy, laparoscopy, and laparoscopic surgery. J Laparoendosc Adv Surg Tech A (1997) 1.18
Does volume of clinical experience affect performance of clinical clerks on surgery exit examinations? Am J Surg (1996) 1.17
Problem-based learning: its role in undergraduate surgical education. Can J Surg (1995) 1.14
Challenges toward standardization of islet isolation technology. Transplant Proc (2001) 1.10
Critical mass of purified islets that induce normoglycemia after implantation into dogs. Diabetes (1988) 1.10
Human pancreas preservation prior to islet isolation. Cold ischemic tolerance. Transplantation (1995) 1.09
Prevention of recurrence of IDDM in islet-transplanted diabetic NOD mice by adjuvant immunotherapy. Diabetes (1992) 1.09
Basal expression of cyclooxygenase-2 and nuclear factor-interleukin 6 are dominant and coordinately regulated by interleukin 1 in the pancreatic islet. Proc Natl Acad Sci U S A (1998) 1.06
Long-term follow-up after transplantation of insulin-producing pancreatic islets into patients with type 1 (insulin-dependent) diabetes mellitus. Diabetologia (1992) 1.06
Continued function of pancreatic islets after transplantation in type I diabetes. Lancet (1989) 1.05
Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production. J Clin Endocrinol Metab (1996) 1.04
Studies of the isolation and viability of human islets of Langerhans. Transplantation (1988) 1.03
Performance of subcutaneously implanted needle-type glucose sensors employing a novel trilayer coating. Anal Chem (1993) 1.02
TRAIL-engineered pancreas-derived mesenchymal stem cells: characterization and cytotoxic effects on pancreatic cancer cells. Cancer Gene Ther (2012) 1.00
Testicular sertoli cells protect islet beta-cells from autoimmune destruction in NOD mice by a transforming growth factor-beta1-dependent mechanism. Diabetes (2000) 1.00
Diabetes induces rapid suppression of adaptive immunity followed by homeostatic T-cell proliferation. Scand J Immunol (2007) 1.00
Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production. J Clin Endocrinol Metab (1994) 0.98
Activation and expression of ERK, JNK, and p38 MAP-kinases in isolated islets of Langerhans: implications for cultured islet survival. FEBS Lett (1999) 0.97
Critical mass of islets that function after implantation in a large mammalian. Horm Metab Res Suppl (1990) 0.97
Effects of intravesicular H+ and extracellular H+ and Zn2+ on insulin secretion in pancreatic beta cells. J Biol Chem (1997) 0.97
Osmotic behavior and transport properties of human islets in a dimethyl sulfoxide solution. Cryobiology (1997) 0.96
Comparison of amperometric methods for detection of exocytosis from single pancreatic beta-cells of different species. Anal Chem (1999) 0.95
In vitro and in vivo expression of Galalpha-(1,3)Gal on porcine islet cells is age dependent. J Endocrinol (2003) 0.95
High yield of rodent islets with intraductal collagenase and stationary digestion--a comparison with standard technique. Cell Transplant (1997) 0.95
Isolation of viable islets of Langerhans from collagenase-perfused canine and human pancreata. Transplant Proc (1987) 0.94
Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells. Lab Invest (2001) 0.94
Risk for developing type 1 (insulin-dependent) diabetes mellitus and the presence of islet 64K antibodies. Diabetologia (1991) 0.93
The glucagon-like peptide-1 receptor agonist exenatide restores impaired pro-islet amyloid polypeptide processing in cultured human islets: implications in type 2 diabetes and islet transplantation. Diabetologia (2012) 0.93
Successful autotransplantation of isolated islets of Langerhans in the cynomolgus monkey. Br J Surg (1986) 0.93
Portal vein thrombosis after transplantation of partially purified pancreatic islets in a combined human liver/islet allograft. Transplantation (1995) 0.93
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Effect of various factors on induction of urinary bladder tumors in animals by N-butyl-n-(4-hydroxybutyl)nitrosoamine. Gan (1973) 0.93
Combined therapy with interleukin-4 and interleukin-10 inhibits autoimmune diabetes recurrence in syngeneic islet-transplanted nonobese diabetic mice. Analysis of cytokine mRNA expression in the graft. Transplantation (1995) 0.93
Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide. Diabetologia (2012) 0.93
Normoglycemia after implantation of purified islet cells in dogs. Can J Surg (1988) 0.92
Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes. Cell Death Dis (2011) 0.92
Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3. Diabetologia (2010) 0.91
Novel approaches toward early diagnosis of islet allograft rejection. Transplantation (2001) 0.91
Modulation of JNK and p38 stress activated protein kinases in isolated islets of Langerhans: insulin as an autocrine survival signal. Ann Surg (2001) 0.91
Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets. Diabetes (1999) 0.90
Viable purified islets of Langerhans from collagenase-perfused human pancreas. Diabetes (1989) 0.90
In vitro and in vivo performance and lifetime of perfluorinated ionomer-coated glucose sensors after high-temperature curing. Anal Chem (1994) 0.89
The determination of membrane permeability coefficients of canine pancreatic islet cells and their application to islet cryopreservation. Cryobiology (1997) 0.89
Testicular Sertoli cells exert both protective and destructive effects on syngeneic islet grafts in non-obese diabetic mice. Diabetologia (2000) 0.89
Insulin resistance and impaired glucose tolerance in the atherosclerosis-prone LA/N corpulent rat. Arteriosclerosis (1988) 0.88
Genetically engineered Sertoli cells are able to survive allogeneic transplantation. Gene Ther (2004) 0.88
Islet cryopreservation using intracellular preservation solutions. Cell Transplant (2001) 0.87
In vivo characterization of transplanted human embryonic stem cell-derived pancreatic endocrine islet cells. Cell Prolif (2008) 0.87
T cell activation and anergy to islet cell antigen in type I diabetes. J Immunol (1995) 0.87
A physiological level of rhubarb fiber increases proglucagon gene expression and modulates intestinal glucose uptake in rats. J Nutr (1997) 0.86
TNF-alpha down-regulates type 1 cytokines and prolongs survival of syngeneic islet grafts in nonobese diabetic mice. J Immunol (1997) 0.86
Streptozotocin-induced diabetes in rats is associated with impaired metabolic availability of vitamin A (retinol). Br J Nutr (1996) 0.86
Rat heart fatty acid-binding protein content is increased in experimental diabetes. Biochem Biophys Res Commun (1994) 0.86
Improved survival of microencapsulated islets during in vitro culture and enhanced metabolic function following transplantation. Diabetologia (2004) 0.86
The metabolic impact of rapamycin (sirolimus) in chronic canine islet graft recipients. Transplantation (1996) 0.86
Use of polyunsaturated fatty acid diet to treat the enhanced intestinal uptake of lipids in streptozotocin diabetic rats. Clin Invest Med (1988) 0.85
Human pancreatic islet cell specific 38 kilodalton autoantigen identified by cytomegalovirus-induced monoclonal islet cell autoantibody. Diabetologia (1990) 0.85
Microbial surveillance of human islet isolation, in vitro culture, and cryopreservation. Clin Invest Med (1995) 0.85
Culture medium modulates proinflammatory conditions of human pancreatic islets before transplantation. Am J Transplant (2006) 0.85