Published in Methods Enzymol on January 01, 1993
The complement protein properdin binds apoptotic T cells and promotes complement activation and phagocytosis. Proc Natl Acad Sci U S A (2008) 1.51
Properdin: New roles in pattern recognition and target clearance. Mol Immunol (2008) 1.16
Native polymeric forms of properdin selectively bind to targets and promote activation of the alternative pathway of complement. Immunobiology (2010) 1.05
Linkage specificity and role of properdin in activation of the alternative complement pathway by fungal glycans. MBio (2011) 0.99
A novel antibody against human properdin inhibits the alternative complement system and specifically detects properdin from blood samples. PLoS One (2014) 0.96
Variability and action mechanism of a family of anticomplement proteins in Ixodes ricinus. PLoS One (2008) 0.94
Local release of properdin in the cellular microenvironment: role in pattern recognition and amplification of the alternative pathway of complement. Front Immunol (2013) 0.94
Identification of a novel mode of complement activation on stimulated platelets mediated by properdin and C3(H2O). J Immunol (2013) 0.87
Complement alternative pathway activation in human nonalcoholic steatohepatitis. PLoS One (2014) 0.75
Properdin Levels in Individuals with Chemotherapy-Induced Neutropenia. Open Forum Infect Dis (2016) 0.75
Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc Natl Acad Sci U S A (1987) 4.19
Isolation and characterization of C1q, a subcomponent of the first component of complement, from human and rabbit sera. Biochem J (1972) 4.06
The proteolytic activation systems of complement. Annu Rev Biochem (1981) 3.85
A second serine protease associated with mannan-binding lectin that activates complement. Nature (1997) 3.64
Structure-function relationships of the complement components. Immunol Today (1989) 2.74
Rat brain Thy-1 glycoprotein. The amino acid sequence, disulphide bonds and an unusual hydrophobic region. Biochem J (1981) 2.63
Isolation, by partial pepsin digestion, of the three collagen-like regions present in subcomponent Clq of the first component of human complement. Biochem J (1976) 2.62
Binding of the pentamer/hexamer forms of mannan-binding protein to zymosan activates the proenzyme C1r2C1s2 complex, of the classical pathway of complement, without involvement of C1q. J Immunol (1990) 2.55
A collagen-like amino acid sequence in a polypeptide chain of human C1q (a subcomponent of the first component of complement). Biochem J (1974) 2.53
Subunit composition and structure of subcomponent C1q of the first component of human complement. Biochem J (1976) 2.46
Activation of the complement system by antibody-antigen complexes: the classical pathway. Adv Protein Chem (1979) 2.39
Human leukocyte C1q receptor binds other soluble proteins with collagen domains. J Exp Med (1990) 2.29
Molecular cloning and characterization of the cDNA coding for C4b-binding protein, a regulatory protein of the classical pathway of the human complement system. Biochem J (1985) 2.19
Islet amyloid formed from diabetes-associated peptide may be pathogenic in type-2 diabetes. Lancet (1987) 2.15
Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q. J Exp Med (1994) 2.15
Binding of pulmonary surfactant proteins A and D to Aspergillus fumigatus conidia enhances phagocytosis and killing by human neutrophils and alveolar macrophages. Infect Immun (1997) 1.97
The binding of complement component C3 to antibody-antigen aggregates after activation of the alternative pathway in human serum. Biochem J (1981) 1.95
C1q: structure, function, and receptors. Immunopharmacology (2000) 1.89
Structures and functions associated with the group of mammalian lectins containing collagen-like sequences. FEBS Lett (1989) 1.87
Pulmonary alveolar proteinosis: clinical aspects and current concepts on pathogenesis. Thorax (2000) 1.85
The biochemistry of complement. Nature (1978) 1.84
Amino acid sequences around the sites of phosphorylation in the pig heart pyruvate dehydrogenase complex. Biochem J (1979) 1.78
The structure and enzymic activities of the C1r and C1s subcomponents of C1, the first component of human serum complement. Biochem J (1977) 1.78
Complement fixation by the F(ab')2-fragment of pepsin-treated rabbit antibody. Immunology (1971) 1.74
Properdin, the terminal complement components, thrombospondin and the circumsporozoite protein of malaria parasites contain similar sequence motifs. Nature (1988) 1.73
Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D. Proc Natl Acad Sci U S A (1999) 1.69
Isolation and characterization of a new member of the scavenger receptor superfamily, glycoprotein-340 (gp-340), as a lung surfactant protein-D binding molecule. J Biol Chem (1997) 1.68
Proteins involved in the activation and control of the two pathways of human complement. Biochem Soc Trans (1983) 1.64
Circular-dichroism and electron-microscopy studies of human subcomponent C1q before and after limited proteolysis by pepsin. Biochem J (1976) 1.61
Deficient hydrophilic lung surfactant proteins A and D with normal surfactant phospholipid molecular species in cystic fibrosis. Am J Respir Cell Mol Biol (1999) 1.57
Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle. Proc Natl Acad Sci U S A (1988) 1.47
Structure, organization, and regulation of the complement genes. Annu Rev Immunol (1988) 1.47
Directional cloning of PCR products using exonuclease III. Nucleic Acids Res (1992) 1.46
Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement. Biochem J (1979) 1.45
Collectins--soluble proteins containing collagenous regions and lectin domains--and their roles in innate immunity. Protein Sci (1994) 1.45
Structural similarities between Thy-1 antigen from rat brain and immunoglobulin. Nature (1979) 1.42
Inhibition of the reconstitution of the haemolytic activity of the first component of human complement by a pepsin-derived fragment of subcomponent C1q. Biochem J (1977) 1.40
Does properdin crosslink the cellular and the humoral immune response? Immunol Today (1999) 1.39
Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophils. J Immunol (1997) 1.37
Identification of the zinc-dependent endothelial cell binding protein for high molecular weight kininogen and factor XII: identity with the receptor that binds to the globular "heads" of C1q (gC1q-R). Proc Natl Acad Sci U S A (1996) 1.34
Purification, characterization and cDNA cloning of human lung surfactant protein D. Biochem J (1992) 1.33
Interaction of fibronectin with C1q and its collagen-like fragment (CLF). FEBS Lett (1981) 1.33
Surfactant proteins A (SP-A) and D (SP-D): levels in human amniotic fluid and localization in the fetal membranes. Biochim Biophys Acta (1994) 1.32
Crystal structure of the trimeric alpha-helical coiled-coil and the three lectin domains of human lung surfactant protein D. Structure (1999) 1.31
Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q. Biochem J (1991) 1.29
Distinct pathways of mannan-binding lectin (MBL)- and C1-complex autoactivation revealed by reconstitution of MBL with recombinant MBL-associated serine protease-2. J Immunol (2000) 1.28
Activation and control of the complement system. Essays Biochem (1986) 1.27
The binding protein for globular heads of complement C1q, gC1qR. Functional expression and characterization as a novel vitronectin binding factor. J Biol Chem (1996) 1.27
Altered airway surfactant phospholipid composition and reduced lung function in asthma. J Appl Physiol (1985) (2000) 1.24
A novel method of purifying lung surfactant proteins A and D from the lung lavage of alveolar proteinosis patients and from pooled amniotic fluid. J Immunol Methods (1998) 1.24
Surfactant proteins A and D protect mice against pulmonary hypersensitivity induced by Aspergillus fumigatus antigens and allergens. J Clin Invest (2001) 1.24
Protective role of lung surfactant protein D in a murine model of invasive pulmonary aspergillosis. Infect Immun (2001) 1.24
Studies on the structure and activity of rabbit Clq (a subcomponent of the first component of complement). Biochem J (1974) 1.22
Expression of the carbohydrate recognition domain of lung surfactant protein D and demonstration of its binding to lipopolysaccharides of gram-negative bacteria. Biochem Biophys Res Commun (1994) 1.20
Human C4-binding protein: N-terminal amino acid sequence analysis and limited proteolysis by trypsin. FEBS Lett (1982) 1.19
Biosynthesis of an insulin precursor by islet tissue of cod (Gadus callarias). Biochem J (1968) 1.18
Neutrophil deactivation by influenza A viruses: mechanisms of protection after viral opsonization with collectins and hemagglutination-inhibiting antibodies. Blood (1996) 1.16
Modular organization of proteins containing C1q-like globular domain. Immunopharmacology (1999) 1.14
Identification of functional domains on gC1Q-R, a cell surface protein that binds to the globular "heads" of C1Q, using monoclonal antibodies and synthetic peptides. Hybridoma (1996) 1.13
Isolation of a human endothelial cell C1q receptor (C1qR). J Leukoc Biol (1993) 1.13
Amino acid sequence of the N-terminal forty-two amino acid residues of the C chain of subcomponent C1q of the first component of human complement. Biochem J (1977) 1.13
Identification of a gC1q-binding protein (gC1q-R) on the surface of human neutrophils. Subcellular localization and binding properties in comparison with the cC1q-R. J Clin Invest (1995) 1.11
Lung surfactant proteins A and D can inhibit specific IgE binding to the allergens of Aspergillus fumigatus and block allergen-induced histamine release from human basophils. Clin Exp Immunol (1997) 1.11
Human ficolin: cDNA cloning, demonstration of peripheral blood leucocytes as the major site of synthesis and assignment of the gene to chromosome 9. Biochem J (1996) 1.11
Interaction of human lung surfactant proteins A and D with mite (Dermatophagoides pteronyssinus) allergens. Clin Exp Immunol (1996) 1.11
Distinct genes for fibroblast and serum C1q. Nature (1981) 1.11
C1: molecular interactions with activating systems. Immunol Today (1991) 1.10
Amino acid sequence of the N-terminal 108 amino acid residues of the B chain of subcomponent C1q of the first component of human complement. Biochem J (1978) 1.09
The roles of surfactant proteins A and D in innate immunity. Immunol Rev (2000) 1.08
Identification of a novel 33-kDa C1q-binding site on human blood platelets. J Immunol (1994) 1.08
Biosynthesis of the first component of complement by human fibroblasts. Biochem J (1977) 1.08
Disulfide bonds are localized within the short consensus repeat units of complement regulatory proteins: C4b-binding protein. Biochemistry (1989) 1.07
The superfamily of C3b/C4b-binding proteins. Fed Proc (1987) 1.04
Inhibitory effect of pulmonary surfactant proteins A and D on allergen-induced lymphocyte proliferation and histamine release in children with asthma. Am J Respir Crit Care Med (1998) 1.04
A genetic defect of the C1q subcomponent of complement associated with childhood (immune complex) nephritis. N Engl J Med (1980) 1.04
Isolation and a partial amino acid sequence of insulin from the islet tissue of cod (Gadus callarias). Biochem J (1968) 1.03
Cloning and characterization of the complementary DNA for the B chain of normal human serum C1q. Philos Trans R Soc Lond B Biol Sci (1984) 1.03
Properdin, a positive regulator of complement activation, is expressed in human T cell lines and peripheral blood T cells. J Immunol (1993) 1.02
Surfactant protein D binding to alveolar macrophages. Biochem J (1994) 1.02
A parallel three stranded alpha-helical bundle at the nucleation site of collagen triple-helix formation. FEBS Lett (1994) 1.02
A homozygous point mutation results in a stop codon in the C1q B-chain of a C1q-deficient individual. Immunogenetics (1988) 1.01
Unusual ultrastructure of complement-component-C4b-binding protein of human complement by synchrotron X-ray scattering and hydrodynamic analysis. Biochem J (1986) 1.01
Purification and characterization of a bovine serum lectin (CL-43) with structural homology to conglutinin and SP-D and carbohydrate specificity similar to mannan-binding protein. J Biol Chem (1993) 1.01
cDNA structure of murine C4b-binding protein, a regulatory component of the serum complement system. Biochemistry (1987) 1.01
The alpha-helical neck region of human lung surfactant protein D is essential for the binding of the carbohydrate recognition domains to lipopolysaccharides and phospholipids. Biochem J (1996) 1.00
Modular organization of carbohydrate recognition domains in animal lectins. Matrix Biol (1997) 1.00
C1q--how many functions? How many receptors? Trends Cell Biol (1998) 0.99
Characterization of C1q-binding material released from the membranes of Raji and U937 cells by limited proteolysis with trypsin. Biochem J (1988) 0.99
The systemic lupus erythematosus (SLE) disease autoantigen-calreticulin can inhibit C1q association with immune complexes. Clin Exp Immunol (1997) 0.99
Lung surfactant proteins involved in innate immunity. Curr Opin Immunol (1999) 0.99
C1q receptors. Clin Exp Immunol (2000) 0.98
C1q-mediated chemotaxis by human neutrophils: involvement of gClqR and G-protein signalling mechanisms. Biochem J (1998) 0.97
Collectin structure: a review. Protein Sci (2000) 0.97
Amylin and the amylin gene: structure, function and relationship to islet amyloid and to diabetes mellitus. Biochim Biophys Acta (1989) 0.96
Measurement of pulmonary status and surfactant protein levels during dexamethasone treatment of neonatal respiratory distress syndrome. Thorax (1996) 0.96
Structural similarity between lung surfactant protein D and conglutinin. Two distinct, C-type lectins containing collagen-like sequences. Eur J Biochem (1993) 0.96
Completion of the amino acid sequences of the A and B chains of subcomponent C1q of the first component of human complement. Biochem J (1982) 0.95
Evidence that the two C1q binding membrane proteins, gC1q-R and cC1q-R, associate to form a complex. J Immunol (1997) 0.95
Similarity in structure between C1q and the collectins as judged by electron microscopy. Behring Inst Mitt (1993) 0.95