Peroxynitrite-mediated cytotoxicity to Trypanosoma cruzi.

PubWeight™: 1.16‹?› | Rank: Top 10%

🔗 View Article (PMID 8323293)

Published in Arch Biochem Biophys on July 01, 1993

Authors

A Denicola1, H Rubbo, D Rodríguez, R Radi

Author Affiliations

1: Departamento de Bioquímica, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.

Articles citing this

Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in gamma interferon receptor or inducible nitric oxide synthase. Infect Immun (1998) 1.89

Myeloperoxidase: a front-line defender against phagocytosed microorganisms. J Leukoc Biol (2012) 1.60

Expression and bactericidal activity of nitric oxide synthase in Brucella suis-infected murine macrophages. Infect Immun (1998) 1.48

Peroxynitrite contributes to the candidacidal activity of nitric oxide-producing macrophages. Infect Immun (1996) 1.35

Surfactant protein A mediates mycoplasmacidal activity of alveolar macrophages by production of peroxynitrite. Proc Natl Acad Sci U S A (1999) 1.29

Peroxynitrite, a stealthy biological oxidant. J Biol Chem (2013) 1.27

Interactions of peroxynitrite with human plasma and its constituents: oxidative damage and antioxidant depletion. Biochem J (1994) 1.20

Intraphagosomal peroxynitrite as a macrophage-derived cytotoxin against internalized Trypanosoma cruzi: consequences for oxidative killing and role of microbial peroxiredoxins in infectivity. J Biol Chem (2010) 1.17

Type 1 immunity provides both optimal mucosal and systemic protection against a mucosally invasive, intracellular pathogen. Infect Immun (2005) 1.13

Stage-dependent role of nitric oxide in control of Trypanosoma cruzi infection. Infect Immun (2001) 1.10

Enhancing effect of oxygen radical scavengers on murine macrophage anticryptococcal activity through production of nitric oxide. Clin Exp Immunol (1996) 1.09

Cytostatic and cytotoxic effects of activated macrophages and nitric oxide donors on Brugia malayi. Infect Immun (1997) 1.07

Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite. Biochem J (2008) 1.01

Enzymes of the antioxidant network as novel determiners of Trypanosoma cruzi virulence. Int J Parasitol (2009) 1.01

Impaired innate immunity in Tlr4(-/-) mice but preserved CD8+ T cell responses against Trypanosoma cruzi in Tlr4-, Tlr2-, Tlr9- or Myd88-deficient mice. PLoS Pathog (2010) 0.98

Trypanosoma cruzi antioxidant enzymes as virulence factors in Chagas disease. Antioxid Redox Signal (2012) 0.95

Nitric oxide as a mediator of inflammation?-You had better believe it. Mediators Inflamm (1995) 0.94

In vivo formation of electron paramagnetic resonance-detectable nitric oxide and of nitrotyrosine is not impaired during murine leishmaniasis. Infect Immun (1998) 0.89

Remarkable role of indoleamine 2,3-dioxygenase and tryptophan metabolites in infectious diseases: potential role in macrophage-mediated inflammatory diseases. Mediators Inflamm (2013) 0.88

PTR1-dependent synthesis of tetrahydrobiopterin contributes to oxidant susceptibility in the trypanosomatid protozoan parasite Leishmania major. Curr Genet (2009) 0.87

Differential regulation of nitric oxide synthase isoforms in experimental acute chagasic cardiomyopathy. Clin Exp Immunol (2000) 0.86

The role of nitrite ion in phagocyte function--perspectives and puzzles. Arch Biochem Biophys (2009) 0.84

Impact of reactive oxygen species (ROS) on the control of parasite loads and inflammation in Leishmania amazonensis infection. Parasit Vectors (2016) 0.77

Biology of Bony Fish Macrophages. Biology (Basel) (2015) 0.77

Evolution of Cell-Autonomous Effector Mechanisms in Macrophages versus Non-Immune Cells. Microbiol Spectr (2016) 0.76

Articles by these authors

Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives. J Biol Chem (1994) 3.64

Deubiquitinases in cancer: new functions and therapeutic options. Oncogene (2011) 2.08

Peroxynitrite reactivity with amino acids and proteins. Amino Acids (2003) 2.06

Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide. J Biol Chem (1994) 2.04

Characterization of early stages in vaccinia virus membrane biogenesis: implications of the 21-kilodalton protein and a newly identified 15-kilodalton envelope protein. J Virol (1997) 2.00

Vaccinia virus 15-kilodalton (A14L) protein is essential for assembly and attachment of viral crescents to virosomes. J Virol (1998) 1.91

Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death. J Immunol (1999) 1.84

Differential inhibitory action of nitric oxide and peroxynitrite on mitochondrial electron transport. Arch Biochem Biophys (1996) 1.83

Peroxynitrite reaction with carbon dioxide/bicarbonate: kinetics and influence on peroxynitrite-mediated oxidations. Arch Biochem Biophys (1996) 1.67

Direct mapping of nuclear shell effects in the heaviest elements. Science (2012) 1.63

Cytochrome c nitration by peroxynitrite. J Biol Chem (2000) 1.53

Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation. J Neurosci (1998) 1.37

Xanthine oxidase-mediated decomposition of S-nitrosothiols. J Biol Chem (1998) 1.34

Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants. Chem Res Toxicol (1999) 1.33

Diffusion of peroxynitrite across erythrocyte membranes. Proc Natl Acad Sci U S A (1998) 1.27

Nitric oxide diffusion in membranes determined by fluorescence quenching. Arch Biochem Biophys (1996) 1.27

Direct EPR detection of the carbonate radical anion produced from peroxynitrite and carbon dioxide. J Biol Chem (1999) 1.26

The apoptosis pathway triggered by the interferon-induced protein kinase PKR requires the third basic domain, initiates upstream of Bcl-2, and involves ICE-like proteases. Virology (1997) 1.26

Chemiluminescent detection of oxidants in vascular tissue. Lucigenin but not coelenterazine enhances superoxide formation. Circ Res (1999) 1.24

Reaction of peroxynitrite with Mn-superoxide dismutase. Role of the metal center in decomposition kinetics and nitration. J Biol Chem (2001) 1.24

Kinetics of cytochrome c2+ oxidation by peroxynitrite: implications for superoxide measurements in nitric oxide-producing biological systems. Arch Biochem Biophys (1995) 1.24

Nitration and inactivation of tyrosine hydroxylase by peroxynitrite. J Biol Chem (2001) 1.22

Attenuated modified vaccinia virus Ankara can be used as an immunizing agent under conditions of preexisting immunity to the vector. J Virol (2000) 1.22

Nitric oxide reaction with lipid peroxyl radicals spares alpha-tocopherol during lipid peroxidation. Greater oxidant protection from the pair nitric oxide/alpha-tocopherol than alpha-tocopherol/ascorbate. J Biol Chem (2000) 1.20

Pathways of peroxynitrite oxidation of thiol groups. Biochem J (1997) 1.19

Detection of H2O2 release from vascular endothelial cells. Free Radic Biol Med (1993) 1.17

Kinetics of peroxynitrite reaction with amino acids and human serum albumin. J Biol Chem (1999) 1.16

Protein tyrosine nitration in hydrophilic and hydrophobic environments. Amino Acids (2006) 1.13

Cytochrome c-catalyzed oxidation of organic molecules by hydrogen peroxide. Arch Biochem Biophys (1991) 1.12

Spin-trapping studies of peroxynitrite decomposition and of 3-morpholinosydnonimine N-ethylcarbamide autooxidation: direct evidence for metal-independent formation of free radical intermediates. Arch Biochem Biophys (1994) 1.11

Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors. J Neurochem (1995) 1.10

On the pH-dependent yield of hydroxyl radical products from peroxynitrite. Free Radic Biol Med (1994) 1.10

Glyceraldehyde-3-phosphate dehydrogenase inactivation by peroxynitrite. Arch Biochem Biophys (1998) 1.09

IL-12 delivery from recombinant vaccinia virus attenuates the vector and enhances the cellular immune response against HIV-1 Env in a dose-dependent manner. J Immunol (1999) 1.08

The major core protein P4a (A10L gene) of vaccinia virus is essential for correct assembly of viral DNA into the nucleoprotein complex to form immature viral particles. J Virol (2001) 1.07

Xanthine oxidase binding to glycosaminoglycans: kinetics and superoxide dismutase interactions of immobilized xanthine oxidase-heparin complexes. Arch Biochem Biophys (1997) 1.07

BRCA1 mRNA expression and outcome to neoadjuvant cisplatin-based chemotherapy in bladder cancer. Ann Oncol (2010) 1.07

Peroxynitrite-dependent tryptophan nitration. Chem Res Toxicol (1996) 1.06

Desferrioxamine inhibition of the hydroxyl radical-like reactivity of peroxynitrite: role of the hydroxamic groups. Free Radic Biol Med (1995) 1.06

Peroxynitrite inactivates thiol-containing enzymes of Trypanosoma cruzi energetic metabolism and inhibits cell respiration. Arch Biochem Biophys (1994) 1.03

The vaccinia virus 39-kDa protein forms a stable complex with the p4a/4a major core protein early in morphogenesis. Virology (1999) 1.03

Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture. Prog Brain Res (1998) 1.02

Galvanic corrosion behavior of titanium implants coupled to dental alloys. J Mater Sci Mater Med (2000) 1.01

Enzymes of the antioxidant network as novel determiners of Trypanosoma cruzi virulence. Int J Parasitol (2009) 1.01

CuZn superoxide dismutase activities from Fasciola hepatica. Parasitology (1998) 1.01

Xanthine oxidase reaction with nitric oxide and peroxynitrite. Arch Biochem Biophys (1998) 1.01

Field trial for reducing porcine Taenia solium cysticercosis in Mexico by systematic vaccination of pigs. Vet Parasitol (1997) 0.99

Sulfenic acid in human serum albumin. Amino Acids (2006) 0.99

Peroxynitrite-mediated oxidation of albumin to the protein-thiyl free radical. FEBS Lett (1994) 0.99

Early prosthetic joint infection: outcomes with debridement and implant retention followed by antibiotic therapy. Clin Microbiol Infect (2010) 0.98

Nitric oxide-dependent production of cGMP supports the survival of rat embryonic motor neurons cultured with brain-derived neurotrophic factor. J Neurosci (1998) 0.97

Physiologic levels of uric acid inhibit xanthine oxidase in human plasma. Pediatr Res (1993) 0.97

Mercaptoethylguanidine and guanidine inhibitors of nitric-oxide synthase react with peroxynitrite and protect against peroxynitrite-induced oxidative damage. J Biol Chem (1997) 0.97

Longitudinal serological and virological study on porcine torovirus (PToV) in piglets from Spanish farms. Vet Microbiol (2010) 0.96

Nitric oxide and peroxynitrite-dependent aconitase inactivation and iron-regulatory protein-1 activation in mammalian fibroblasts. Arch Biochem Biophys (1998) 0.96

Management of catheter-related Staphylococcus aureus bacteremia: when may sonographic study be unnecessary? Eur J Clin Microbiol Infect Dis (2003) 0.96

L-arginine-dependent suppression of apoptosis in Trypanosoma cruzi: contribution of the nitric oxide and polyamine pathways. Proc Natl Acad Sci U S A (2001) 0.96

Direct mass measurements above uranium bridge the gap to the island of stability. Nature (2010) 0.96

Oxidation of the albumin thiol to sulfenic acid and its implications in the intravascular compartment. Braz J Med Biol Res (2009) 0.95

Lymphocytic hypophysitis successfully treated with azathioprine: first case report. J Neurol Neurosurg Psychiatry (2003) 0.94

The caveolin-1 connection to cell death and survival. Curr Mol Med (2013) 0.94

Enhanced CD8+ T cell response to HIV-1 env by combined immunization with influenza and vaccinia virus recombinants. Vaccine (1999) 0.93

Peroxynitrite-mediated decarboxylation of pyruvate to both carbon dioxide and carbon dioxide radical anion. Chem Res Toxicol (1997) 0.92

TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis. Cell Death Differ (2012) 0.92

Ca2+-independent permeabilization of the inner mitochondrial membrane by peroxynitrite is mediated by membrane protein thiol cross-linking and lipid peroxidation. Arch Biochem Biophys (1997) 0.92

Tuberculosis in a wild subantarctic fur seal from Argentina. J Wildl Dis (1999) 0.91

Oxygen radical-nitric oxide reactions in vascular diseases. Adv Pharmacol (1995) 0.91

National prevalence of nosocomial infections. Cuba 2004. J Hosp Infect (2008) 0.90

Diffusion of peroxynitrite in the presence of carbon dioxide. Arch Biochem Biophys (1999) 0.90

De novo tumors after orthotopic liver transplantation. Transplant Proc (2002) 0.90

Nitric oxide-derived oxidants with a focus on peroxynitrite: molecular targets, cellular responses and therapeutic implications. Curr Pharm Des (2011) 0.89

Comparison of the effects of superoxide dismutase and cytochrome c on luminol chemiluminescence produced by xanthine oxidase-catalyzed reactions. Biochim Biophys Acta (1989) 0.89

Functional analysis of OleY L-oleandrosyl 3-O-methyltransferase of the oleandomycin biosynthetic pathway in Streptomyces antibioticus. J Bacteriol (2001) 0.88

Luminol chemiluminescence using xanthine and hypoxanthine as xanthine oxidase substrates. Free Radic Biol Med (1990) 0.88

Succinate-dependent metabolism in Trypanosoma cruzi epimastigotes. Mol Biochem Parasitol (1992) 0.88

Do specific EEG frequencies indicate different processes during mental calculation? Neurosci Lett (1999) 0.87

Peroxynitrite affects Ca2+ transport in Trypanosoma cruzi. Mol Biochem Parasitol (1999) 0.86

The contribution of vascular endothelial xanthine dehydrogenase/oxidase to oxygen-mediated cell injury. Arch Biochem Biophys (1992) 0.86

Enhanced CD8+ T cell immune response against a V3 loop multi-epitope polypeptide (TAB13) of HIV-1 Env after priming with purified fusion protein and booster with modified vaccinia virus Ankara (MVA-TAB) recombinant: a comparison of humoral and cellular immune responses with the vaccinia virus Western Reserve (WR) vector. Vaccine (2001) 0.86

The expression of an abscisic acid-responsive glycine-rich protein coincides with the level of seed dormancy in Fagus sylvatica. Plant Cell Physiol (1997) 0.86

Molecular and antigenic characterization of rabbit hemorrhagic disease virus isolated in Cuba indicates a distinct antigenic subtype. Arch Virol (2007) 0.86

Protective immune response against cutaneous leishmaniasis by prime/booster immunization regimens with vaccinia virus recombinants expressing Leishmania infantum p36/LACK and IL-12 in combination with purified p36. Microbes Infect (2001) 0.86

Protein 3-nitrotyrosine formation during Trypanosoma cruzi infection in mice. Braz J Med Biol Res (2005) 0.85

Subdural hematomas of the posterior fossa in normal-weight newborns. Report of two cases. J Neurosurg (1984) 0.85

Reaction between peroxynitrite and hydrogen peroxide: formation of oxygen and slowing of peroxynitrite decomposition. Chem Res Toxicol (1995) 0.85

Genetic evidence for two sibling species within Contracaecum ogmorhini Johnston & Mawson, 1941 (Nematoda: Anisakidae) from otariid seals of boreal and austral regions. Syst Parasitol (2003) 0.85

A new protein phosphatase 2C (FsPP2C1) induced by abscisic acid is specifically expressed in dormant beechnut seeds. Plant Physiol (2001) 0.84

Oxidation of ubiquinol by peroxynitrite: implications for protection of mitochondria against nitrosative damage. Biochem J (2000) 0.84

Development of a nasal vaccine for chronic hepatitis B infection that uses the ability of hepatitis B core antigen to stimulate a strong Th1 response against hepatitis B surface antigen. Immunol Cell Biol (2004) 0.83

First Penning trap mass measurements beyond the proton drip line. Phys Rev Lett (2008) 0.83

Formation of spin trap adducts during the decomposition of peroxynitrite. Arch Biochem Biophys (1998) 0.83

Nitric oxide: a central regulatory species in pulmonary oxidant reactions. Am J Physiol (1995) 0.83

Formation of lipid-protein adducts in low-density lipoprotein by fluxes of peroxynitrite and its inhibition by nitric oxide. Arch Biochem Biophys (2001) 0.82

Frequent somatic mutations in components of the RNA processing machinery in chronic lymphocytic leukemia. Leukemia (2012) 0.82

Direct evidence for apo B-100-mediated copper reduction: studies with purified apo B-100 and detection of tryptophanyl radicals. Arch Biochem Biophys (2000) 0.82

[Sudden death in surgically treated tetralogy of Fallot]. G Ital Cardiol (1985) 0.82