Published in Can Med Assoc J on February 05, 1977
Antibiotic misuse in a pediatric teaching hospital. Can Med Assoc J (1980) 1.22
Use and abuse of antibiotics. Br J Clin Pharmacol (1984) 0.85
Antimicrobial use in a small rural hospital. Can Fam Physician (1984) 0.80
Antimicrobial resistance. Bull World Health Organ (1983) 0.79
Antimicrobial drug use in hospitals. Can Med Assoc J (1977) 0.75
Compulsive antibiotic training. Can Fam Physician (1988) 0.75
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Changing ecology of bacterial infections as related to antibacterial therapy. J Infect Dis (1970) 7.72
Letter: Ampicillin-resistant Haemophilus influenzae meningitis. Lancet (1974) 5.33
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Nature and extent of penicillin side-reactions, with particular reference to fatalities from anaphylactic shock. Bull World Health Organ (1968) 2.79
Type-specific and cross-reactive antibodies in gram-negative bacteremia. N Engl J Med (1972) 2.42
Editorial: Gram-negative-rod bacteremia. N Engl J Med (1974) 2.36
Testing the physician's knowledge of antibiotic use: Self-assessment and learning via videotape. N Engl J Med (1975) 2.35
This is medical progress? Trends and consequences of antibiotic use in the United States. JAMA (1974) 2.01
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Infectious drug resistance in enteric bacteria. N Engl J Med (1966) 1.64
Antibiotic-induced suprainfection. J Infect Dis (1969) 1.42
Measurement of health status. Ascertaining the minimal clinically important difference. Control Clin Trials (1989) 15.99
Guidelines for reading literature reviews. CMAJ (1988) 10.90
Users' guides to the medical literature. VI. How to use an overview. Evidence-Based Medicine Working Group. JAMA (1994) 10.80
Determining a minimal important change in a disease-specific Quality of Life Questionnaire. J Clin Epidemiol (1994) 9.50
Development and validation of a questionnaire to measure asthma control. Eur Respir J (1999) 9.35
The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials. J Clin Epidemiol (1997) 9.01
The 6-minute walk: a new measure of exercise capacity in patients with chronic heart failure. Can Med Assoc J (1985) 8.06
How to keep up with the medical literature: V. Access by personal computer to the medical literature. Ann Intern Med (1986) 7.36
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Measuring quality of life in children with asthma. Qual Life Res (1996) 6.76
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Measuring disease-specific quality of life in clinical trials. CMAJ (1986) 5.56
Evaluation of impairment of health related quality of life in asthma: development of a questionnaire for use in clinical trials. Thorax (1992) 5.37
Risk factors for gastrointestinal bleeding in critically ill patients. Canadian Critical Care Trials Group. N Engl J Med (1994) 5.19
Measuring quality of life in asthma. Am Rev Respir Dis (1993) 4.97
Randomised controlled trial of respiratory rehabilitation. Lancet (1994) 4.74
Meta-analysis of respiratory rehabilitation in chronic obstructive pulmonary disease. Lancet (1996) 4.65
Assessing the minimal important difference in symptoms: a comparison of two techniques. J Clin Epidemiol (1996) 4.55
Validation of an index of the quality of review articles. J Clin Epidemiol (1991) 4.54
Cardiac rehabilitation after myocardial infarction. Combined experience of randomized clinical trials. JAMA (1988) 4.46
Effect of encouragement on walking test performance. Thorax (1984) 4.44
Practitioners of evidence based care. Not all clinicians need to appraise evidence from scratch but all need some skills. BMJ (2000) 4.41
The science of reviewing research. Ann N Y Acad Sci (1993) 4.15
Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients. Ann Intern Med (1998) 4.01
Development and validation of the Mini Asthma Quality of Life Questionnaire. Eur Respir J (1999) 4.00
Systematic implementation of an advance directive program in nursing homes: a randomized controlled trial. JAMA (2000) 3.87
Measuring quality of life in the parents of children with asthma. Qual Life Res (1996) 3.82
The influence of dietary and nondietary calcium supplementation on blood pressure: an updated metaanalysis of randomized controlled trials. Am J Hypertens (1999) 3.72
Canadian physicians' attitudes about and preferences regarding clinical practice guidelines. CMAJ (1997) 3.56
Users' guides to the medical literature. JAMA (1993) 3.56
Physician interpretations and textbook definitions of blinding terminology in randomized controlled trials. JAMA (2001) 3.32
Interpreting small differences in functional status: the Six Minute Walk test in chronic lung disease patients. Am J Respir Crit Care Med (1997) 3.28
Stress ulcer prophylaxis in critically ill patients. Resolving discordant meta-analyses. JAMA (1996) 3.21
Intention-to-treat principle. CMAJ (2001) 3.20
Determinants in Canadian health care workers of the decision to withdraw life support from the critically ill. Canadian Critical Care Trials Group. JAMA (1995) 3.08
Effect of HMGcoA reductase inhibitors on stroke. A meta-analysis of randomized, controlled trials. Ann Intern Med (1998) 3.07
Endoscopic therapy for acute nonvariceal upper gastrointestinal hemorrhage: a meta-analysis. Gastroenterology (1992) 3.06
Isoniazid prophylaxis for tuberculosis in HIV infection: a meta-analysis of randomized controlled trials. AIDS (1999) 3.04
Clinical impact versus factor analysis for quality of life questionnaire construction. J Clin Epidemiol (1997) 2.98
Effect of calcium supplementation on pregnancy-induced hypertension and preeclampsia: a meta-analysis of randomized controlled trials. JAMA (1996) 2.98
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When should an effective treatment be used? Derivation of the threshold number needed to treat and the minimum event rate for treatment. J Clin Epidemiol (2001) 2.84
Rules of evidence and clinical recommendations on the use of antithrombotic agents. Chest (1992) 2.81
Development and testing of a new measure of health status for clinical trials in rhinoconjunctivitis. Clin Exp Allergy (1991) 2.80
A menopause-specific quality of life questionnaire: development and psychometric properties. Maturitas (1996) 2.74
Residents' experiences of abuse, discrimination and sexual harassment during residency training. McMaster University Residency Training Programs. CMAJ (1996) 2.71
Reamed versus nonreamed intramedullary nailing of lower extremity long bone fractures: a systematic overview and meta-analysis. J Orthop Trauma (2000) 2.69
The rational clinical examination. Is this patient having a myocardial infarction? JAMA (1998) 2.66
How should we measure function in patients with chronic heart and lung disease? J Chronic Dis (1985) 2.61
User's guide to the orthopaedic literature: how to use an article about a surgical therapy. J Bone Joint Surg Am (2001) 2.58
Clinical recommendations using levels of evidence for antithrombotic agents. Chest (1995) 2.52
Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst Rev (2002) 2.50
An index of scientific quality for health reports in the lay press. J Clin Epidemiol (1993) 2.47
Reporting of 6-month vs 12-month data in a clinical trial of celecoxib. JAMA (2001) 2.42
Relation of distribution- and anchor-based approaches in interpretation of changes in health-related quality of life. Med Care (2001) 2.36
Sensitivity to change of the Roland-Morris Back Pain Questionnaire: part 1. Phys Ther (1998) 2.35
Treatment of open fractures of the shaft of the tibia. J Bone Joint Surg Br (2001) 2.33
Selective decontamination of the digestive tract. An overview. Chest (1994) 2.28
Should unpublished data be included in meta-analyses? Current convictions and controversies. JAMA (1993) 2.26
A framework for clinical evaluation of diagnostic technologies. CMAJ (1986) 2.26
Agreement among reviewers of review articles. J Clin Epidemiol (1991) 2.25
Practice guidelines. What are internists looking for? J Gen Intern Med (1996) 2.17
Should study subjects see their previous responses? J Chronic Dis (1985) 2.17
Transferring evidence from research into practice: 1. The role of clinical care research evidence in clinical decisions. ACP J Club (1996) 2.10
Effects of dietary calcium supplementation on blood pressure. A meta-analysis of randomized controlled trials. JAMA (1996) 2.08
Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain. N Engl J Med (1973) 2.06
How to use an article on therapy or prevention: pneumonia prevention using subglottic secretion drainage. Crit Care Med (1997) 2.03
Users' guides to the medical literature: XVII. How to use guidelines and recommendations about screening. Evidence-Based Medicine Working Group. JAMA (1999) 1.96
Quality of life in stage II breast cancer: an instrument for clinical trials. J Clin Oncol (1988) 1.93
Users' guides to the medical literature. XI. How to use an article about a clinical utilization review. Evidence-Based Medicine Working Group. JAMA (1996) 1.91
Long-term effects of outpatient rehabilitation of COPD: A randomized trial. Chest (2000) 1.91
Treatment of homocystinuria with a low-methionine diet, supplemental cystine, and a methyl donor. Lancet (1968) 1.90
Development of a self-reported Chronic Respiratory Questionnaire (CRQ-SR). Thorax (2001) 1.89
Parkinson's disease: a disorder due to nigral glutathione deficiency? Neurosci Lett (1982) 1.89
Bronchodilators in chronic air-flow limitation. Effects on airway function, exercise capacity, and quality of life. Am Rev Respir Dis (1987) 1.85
Interpretation of treatment changes in 6-minute walk distance in patients with COPD. Eur Respir J (2008) 1.82
Interobserver variation in interpreting chest radiographs for the diagnosis of acute respiratory distress syndrome. Am J Respir Crit Care Med (2000) 1.81
Urinary screening tests in the prevention of mental deficiency. Can Med Assoc J (1966) 1.81
Quality of life issues in women with vertebral fractures due to osteoporosis. Arthritis Rheum (1993) 1.80
The diagnosis of dementia. CMAJ (1987) 1.76
How to keep up with the medical literature: IV. Using the literature to solve clinical problems. Ann Intern Med (1986) 1.75
Effectiveness of a geriatric day hospital. CMAJ (1991) 1.74
A comparison of seven-point and visual analogue scales. Data from a randomized trial. Control Clin Trials (1990) 1.70
Evidence-based medicine in anesthesiology. Anesth Analg (2001) 1.67
Discrimination and abuse experienced by general internists in Canada. J Gen Intern Med (1995) 1.67
Confidence in life-support decisions in the intensive care unit: a survey of healthcare workers. Canadian Critical Care Trials Group. Crit Care Med (1998) 1.63
Technical pitfalls leading to errors in the quantitation of plasma amino acids. Clin Chim Acta (1969) 1.62
Mechanical ventilator weaning protocols driven by nonphysician health-care professionals: evidence-based clinical practice guidelines. Chest (2001) 1.60
How to keep up with the medical literature: II. Deciding which journals to read regularly. Ann Intern Med (1986) 1.57
International approaches to the prescription of long-term oxygen therapy. Eur Respir J (2001) 1.57
Interobserver and intraobserver variation in the assessment of the healing of tibial fractures after intramedullary fixation. J Bone Joint Surg Br (2002) 1.53