Published in Proc Natl Acad Sci U S A on June 15, 1993
cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci U S A (1996) 16.69
Helicobacter pylori. Clin Microbiol Rev (1997) 9.22
Pathogenesis of Helicobacter pylori infection. Clin Microbiol Rev (2006) 7.72
A whole-genome microarray reveals genetic diversity among Helicobacter pylori strains. Proc Natl Acad Sci U S A (2000) 6.85
Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease. J Exp Med (1994) 6.24
Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation. Proc Natl Acad Sci U S A (2000) 5.07
Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin. Proc Natl Acad Sci U S A (1999) 4.55
Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro. Infect Immun (1995) 4.19
Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype. J Clin Pathol (1995) 3.86
Helicobacter pylori CagA protein can be tyrosine phosphorylated in gastric epithelial cells. J Exp Med (2000) 3.74
Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites. Proc Natl Acad Sci U S A (2002) 3.50
CagA/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cell lines. J Clin Pathol (1994) 3.48
Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strains. Gut (1997) 3.39
A novel family of phospholipase D homologues that includes phospholipid synthases and putative endonucleases: identification of duplicated repeats and potential active site residues. Protein Sci (1996) 3.34
Population genetic analysis of Helicobacter pylori by multilocus enzyme electrophoresis: extensive allelic diversity and recombinational population structure. J Bacteriol (1996) 3.32
Variants of the 3' region of the cagA gene in Helicobacter pylori isolates from patients with different H. pylori-associated diseases. J Clin Microbiol (1998) 3.31
Global transposon mutagenesis and essential gene analysis of Helicobacter pylori. J Bacteriol (2004) 3.25
Serologic detection of infection with cagA+ Helicobacter pylori strains. J Clin Microbiol (1995) 3.23
Creating and maintaining the gastrointestinal ecosystem: what we know and need to know from gnotobiology. Microbiol Mol Biol Rev (1998) 3.09
Analysis and typing of the vacA gene from cagA-positive strains of Helicobacter pylori isolated in Japan. J Clin Microbiol (1997) 2.89
Major virulence factors, VacA and CagA, are commonly positive in Helicobacter pylori isolates in Japan. Gut (1998) 2.84
Typing of Helicobacter pylori vacA gene and detection of cagA gene by PCR and reverse hybridization. J Clin Microbiol (1998) 2.77
Expanding allelic diversity of Helicobacter pylori vacA. J Clin Microbiol (1998) 2.73
Heterogeneity in the Helicobacter pylori vacA and cagA genes: association with gastroduodenal disease in South Africa? Gut (1999) 2.43
Quasispecies development of Helicobacter pylori observed in paired isolates obtained years apart from the same host. J Infect Dis (2000) 2.42
pH-regulated gene expression of the gastric pathogen Helicobacter pylori. Infect Immun (2003) 2.41
Induction of host signal transduction pathways by Helicobacter pylori. Proc Natl Acad Sci U S A (1997) 2.38
Mutation of the cytotoxin-associated cagA gene does not affect the vacuolating cytotoxin activity of Helicobacter pylori. Infect Immun (1994) 2.37
Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori. J Clin Pathol (1995) 2.37
Virulence factors of Helicobacter pylori responsible for gastric diseases in Mongolian gerbil. J Exp Med (2000) 2.37
Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation. Gut (2003) 2.37
Vacuolating cytotoxin of Helicobacter pylori plays a role during colonization in a mouse model of infection. Infect Immun (2001) 2.30
Diversity of Helicobacter pylori vacA and cagA genes and relationship to VacA and CagA protein expression, cytotoxin production, and associated diseases. J Clin Microbiol (1998) 2.26
Structure of cag pathogenicity island in Japanese Helicobacter pylori isolates. Gut (1999) 2.25
Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments. Proc Natl Acad Sci U S A (1994) 2.19
Equally high prevalences of infection with cagA-positive Helicobacter pylori in Chinese patients with peptic ulcer disease and those with chronic gastritis-associated dyspepsia. J Clin Microbiol (1997) 2.18
Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori. Nat Rev Microbiol (2013) 2.16
Motility of Helicobacter pylori is coordinately regulated by the transcriptional activator FlgR, an NtrC homolog. J Bacteriol (1999) 2.16
Cag pathogenicity island-specific responses of gastric epithelial cells to Helicobacter pylori infection. Proc Natl Acad Sci U S A (2002) 2.16
Differences in interleukin 8 expression in Helicobacter pylori-infected gastric mucosa tissues from patients in Bhutan and the Dominican Republic. Hum Pathol (2014) 2.07
The complete genome sequence of Helicobacter pylori strain G27. J Bacteriol (2008) 2.05
Allelic Variation within Helicobacter pylori babA and babB. Infect Immun (2001) 2.02
Role of the host in pathogenesis of Helicobacter-associated gastritis: H. felis infection of inbred and congenic mouse strains. Infect Immun (1996) 1.98
Correlation between vacuolating cytotoxin production by Helicobacter pylori isolates in vitro and in vivo. Infect Immun (1993) 1.97
The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity. Proc Natl Acad Sci U S A (1998) 1.95
Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease. Infect Immun (1995) 1.93
Metabolism and genetics of Helicobacter pylori: the genome era. Microbiol Mol Biol Rev (1999) 1.92
Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin. J Clin Invest (1998) 1.89
Expression of the human cell surface glycoconjugates Lewis x and Lewis y by Helicobacter pylori isolates is related to cagA status. Infect Immun (1996) 1.88
Detection of Helicobacter pylori gene expression in human gastric mucosa. J Clin Microbiol (1995) 1.86
cagA-positive Helicobacter pylori populations in China and The Netherlands are distinct. Infect Immun (1998) 1.84
Functional analysis of the Helicobacter pylori cag pathogenicity island reveals both VirD4-CagA-dependent and VirD4-CagA-independent mechanisms. Infect Immun (2002) 1.84
Atrophic gastric changes in both Helicobacter felis and Helicobacter pylori infected mice are host dependent and separate from antral gastritis. Gut (1996) 1.82
Introduction of unmarked mutations in the Helicobacter pylori vacA gene with a sucrose sensitivity marker. Infect Immun (1997) 1.82
Serum CagA antibodies in asymptomatic subjects and patients with peptic ulcer: lack of correlation of IgG antibody in patients with peptic ulcer or asymptomatic Helicobacter pylori gastritis. J Clin Pathol (1996) 1.81
Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies. Infect Immun (1995) 1.79
Purification of Helicobacter pylori superoxide dismutase and cloning and sequencing of the gene. Infect Immun (1993) 1.78
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. Nature (2014) 1.77
Helicobacter pylori usurps cell polarity to turn the cell surface into a replicative niche. PLoS Pathog (2009) 1.73
Diagnosis of Helicobacter pylori infection by PCR: comparison with other invasive techniques and detection of cagA gene in gastric biopsy specimens. J Clin Microbiol (1995) 1.72
Identification and characterization of an operon of Helicobacter pylori that is involved in motility and stress adaptation. J Bacteriol (1997) 1.70
Antrum- and corpus mucosa-infiltrating CD4(+) lymphocytes in Helicobacter pylori gastritis display a Th1 phenotype. Infect Immun (1998) 1.67
Experimental infection of Mongolian gerbils with wild-type and mutant Helicobacter pylori strains. Infect Immun (1998) 1.64
Inability of an isogenic urease-negative mutant stain of Helicobacter mustelae to colonize the ferret stomach. Infect Immun (1995) 1.63
Geographic differences in gastric cancer incidence can be explained by differences between Helicobacter pylori strains. Intern Med (2008) 1.62
The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation. EMBO J (2003) 1.60
Identification of Helicobacter pylori genes that contribute to stomach colonization. Infect Immun (2006) 1.59
A revised annotation and comparative analysis of Helicobacter pylori genomes. Nucleic Acids Res (2003) 1.59
Proteins encoded by the cag pathogenicity island of Helicobacter pylori are required for NF-kappaB activation. Infect Immun (1998) 1.58
Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection. Infect Immun (1997) 1.57
Cytotoxin production by Helicobacter pylori from patients with upper gastrointestinal tract diseases. J Clin Microbiol (1995) 1.55
Tyrosine-phosphorylated bacterial proteins: Trojan horses for the host cell. J Exp Med (2000) 1.55
Identification and analysis of a new vacA genotype variant of Helicobacter pylori in different patient groups in Germany. J Clin Microbiol (1998) 1.51
Helicobacter pylori CagA status associated with gastric cancer incidence rate variability in Costa Rican regions. J Gastroenterol (2006) 1.49
Iron and pH homeostasis intersect at the level of Fur regulation in the gastric pathogen Helicobacter pylori. Infect Immun (2006) 1.48
Human and Helicobacter pylori coevolution shapes the risk of gastric disease. Proc Natl Acad Sci U S A (2014) 1.48
Evidence for a conjugation-like mechanism of DNA transfer in Helicobacter pylori. J Bacteriol (1998) 1.47
HP0333, a member of the dprA family, is involved in natural transformation in Helicobacter pylori. J Bacteriol (1999) 1.46
Identification of target genes regulated by the two-component system HP166-HP165 of Helicobacter pylori. J Bacteriol (2002) 1.44
Molecular epidemiology, population genetics, and pathogenic role of Helicobacter pylori. Infect Genet Evol (2011) 1.44
Focal adhesion kinase is a substrate and downstream effector of SHP-2 complexed with Helicobacter pylori CagA. Mol Cell Biol (2006) 1.43
Adaptive mutation and cocolonization during Helicobacter pylori infection of gnotobiotic piglets. Infect Immun (1995) 1.43
Distinct variants of Helicobacter pylori cagA are associated with vacA subtypes. J Clin Microbiol (1999) 1.43
Analysis of Helicobacter pylori genotypes and correlation with clinical outcome in Turkey. J Clin Microbiol (2004) 1.42
Helicobacter pylori-specific CD4+ T-cell clones from peripheral blood and gastric biopsies. Infect Immun (1995) 1.39
Helicobacter pylori infection density and gastric inflammation in duodenal ulcer and non-ulcer subjects. Gut (1995) 1.39
Colonization of Mexican patients by multiple Helicobacter pylori strains with different vacA and cagA genotypes. J Clin Microbiol (1999) 1.39
Gastric cancer: overview. Gastroenterol Clin North Am (2013) 1.37
Association between Helicobacter pylori virulence factors and gastroduodenal diseases in Okinawa, Japan. J Clin Microbiol (2011) 1.37
Polymorphisms of Helicobacter pylori HP0638 reflect geographic origin and correlate with cagA status. J Clin Microbiol (2002) 1.35
Effect of growth phase and acid shock on Helicobacter pylori cagA expression. Infect Immun (1996) 1.35
A comprehensive sequence and disease correlation analyses for the C-terminal region of CagA protein of Helicobacter pylori. PLoS One (2009) 1.34
Correlation between cag pathogenicity island composition and Helicobacter pylori-associated gastroduodenal disease. Infect Immun (2003) 1.32
Evaluation of the association of nine Helicobacter pylori virulence factors with strains involved in low-grade gastric mucosa-associated lymphoid tissue lymphoma. Infect Immun (2004) 1.30
Determination of Helicobacter pylori virulence by simple gene analysis of the cag pathogenicity island. Clin Diagn Lab Immunol (2001) 1.29
Analysis of antimicrobial susceptibility and virulence factors in Helicobacter pylori clinical isolates. BMC Gastroenterol (2003) 1.29
Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet (1983) 23.90
Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med (1991) 23.89
In vivo footprinting of a muscle specific enhancer by ligation mediated PCR. Science (1989) 10.87
DNA diversity among clinical isolates of Helicobacter pylori detected by PCR-based RAPD fingerprinting. Nucleic Acids Res (1992) 8.86
Isolation of Helicobacter pylori from human faeces. Lancet (1992) 7.32
Gastric Campylobacter-like organisms, gastritis, and peptic ulcer disease. Gastroenterology (1987) 7.27
Purification and characterization of the vacuolating toxin from Helicobacter pylori. J Biol Chem (1992) 6.54
Characterization of and human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity. Infect Immun (1990) 5.85
Prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic persons. N Engl J Med (1989) 5.78
Plasmid transformation of Escherichia coli and other bacteria. Methods Enzymol (1991) 5.21
Intrafamilial clustering of Helicobacter pylori infection. N Engl J Med (1990) 5.09
Antibody to the gastric campylobacter-like organism ("Campylobacter pyloridis")--clinical correlations and distribution in the normal population. J Med Microbiol (1986) 4.95
Epidemiology of Helicobacter pylori in an asymptomatic population in the United States. Effect of age, race, and socioeconomic status. Gastroenterology (1991) 4.86
Expression of Helicobacter pylori urease genes in Escherichia coli grown under nitrogen-limiting conditions. J Bacteriol (1992) 4.02
Characterization of foot-and-mouth disease virus gene products with antisera against bacterially synthesized fusion proteins. J Virol (1986) 3.89
Effect of urease on HeLa cell vacuolation induced by Helicobacter pylori cytotoxin. Infect Immun (1991) 3.57
Construction of a Helicobacter pylori genome map and demonstration of diversity at the genome level. J Bacteriol (1992) 3.16
Cloning and genetic characterization of a Helicobacter pylori flagellin gene. Mol Microbiol (1992) 2.97
Large, identical, tandem repeating units in the C protein alpha antigen gene, bca, of group B streptococci. Proc Natl Acad Sci U S A (1992) 2.65
Seroepidemiology of Helicobacter pylori infection in India. Comparison of developing and developed countries. Dig Dis Sci (1991) 2.63
Expression of 120 kilodalton protein and cytotoxicity in Helicobacter pylori. J Clin Pathol (1992) 2.60
Expression and immunological properties of the five subunits of pertussis toxin. Infect Immun (1987) 2.59
Seroepidemiology of Campylobacter pyloridis. N Z Med J (1986) 2.52
DNA cloning of Plasmodium falciparum circumsporozoite gene: amino acid sequence of repetitive epitope. Science (1984) 2.47
Immunoglobulin-like PapD chaperone caps and uncaps interactive surfaces of nascently translocated pilus subunits. Proc Natl Acad Sci U S A (1991) 2.25
Antibody response of patients against a 120 kDa surface protein of Campylobacter pylori. Zentralbl Bakteriol Mikrobiol Hyg A (1988) 2.18
Growth of Helicobacter pylori in media containing cyclodextrins. J Clin Microbiol (1993) 2.17
Secretion across the bacterial outer membrane. Trends Genet (1992) 2.14
Characteristics of Helicobacter pylori variants selected for urease deficiency. Infect Immun (1992) 2.01
The Trypanosoma cruzi neuraminidase contains sequences similar to bacterial neuraminidases, YWTD repeats of the low density lipoprotein receptor, and type III modules of fibronectin. J Exp Med (1991) 1.92
Genetics of Campylobacter and Helicobacter. Annu Rev Microbiol (1992) 1.65
Serodiagnosis of Helicobacter pylori infections with an enzyme immunoassay using the chromatographically purified 120 kilodalton protein. Eur J Clin Microbiol Infect Dis (1992) 1.35
The phenotypically variable surface protein of Trichomonas vaginalis has a single, tandemly repeated immunodominant epitope. Infect Immun (1991) 1.28
PCR amplification techniques for chromosome walking. Trends Biotechnol (1992) 1.13
cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci U S A (1996) 16.69
The genome sequence of Schizosaccharomyces pombe. Nature (2002) 14.26
Binding of hepatitis C virus to CD81. Science (1998) 12.40
Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease. J Exp Med (1994) 6.24
Development of a mouse model of Helicobacter pylori infection that mimics human disease. Science (1995) 5.73
Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype. J Clin Pathol (1995) 3.86
T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease. J Immunol (1997) 3.61
CagA/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cell lines. J Clin Pathol (1994) 3.48
Allelic variation in the cagA gene of Helicobacter pylori obtained from Korea compared to the United States. Am J Gastroenterol (1996) 3.20
Mutants of pertussis toxin suitable for vaccine development. Science (1989) 2.89
Prevalence, species differentiation, and toxigenicity of Aeromonas strains in cases of childhood gastroenteritis and in controls. J Clin Microbiol (1986) 2.88
Expression of 120 kilodalton protein and cytotoxicity in Helicobacter pylori. J Clin Pathol (1992) 2.60
Relationship between the cagA 3' repeat region of Helicobacter pylori, gastric histology, and susceptibility to low pH. Gastroenterology (1999) 2.44
Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori. J Clin Pathol (1995) 2.37
Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo. Proc Natl Acad Sci U S A (1995) 2.33
Long-term analysis of clinical outcome and complications in locally advanced cervical cancer patients administered concomitant chemoradiation followed by radical surgery. Gynecol Oncol (2010) 2.27
Bafilomycin A1 inhibits Helicobacter pylori-induced vacuolization of HeLa cells. Mol Microbiol (1993) 2.24
American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and European Thyroid Association medical guidelines for clinical practice for the diagnosis and management of thyroid nodules: executive summary of recommendations. J Endocrinol Invest (2010) 2.20
Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments. Proc Natl Acad Sci U S A (1994) 2.19
Growth of Helicobacter pylori in media containing cyclodextrins. J Clin Microbiol (1993) 2.17
Low pH activates the vacuolating toxin of Helicobacter pylori, which becomes acid and pepsin resistant. J Biol Chem (1995) 2.17
Detection in an enzyme immunoassay of an immune response to a recombinant fragment of the 128 kilodalton protein (CagA) of Helicobacter pylori. Eur J Clin Microbiol Infect Dis (1993) 2.02
Molecular epidemiology of Helicobacter pylori: separation of H. pylori from East Asian and non-Asian countries. Epidemiol Infect (2000) 1.97
The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity. Proc Natl Acad Sci U S A (1998) 1.95
CD81 extracellular domain 3D structure: insight into the tetraspanin superfamily structural motifs. EMBO J (2001) 1.90
Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C. J Exp Med (1993) 1.90
Presence of antibodies against Helicobacter pylori and its heat-shock protein 60 in the serum of patients with Sjögren's syndrome. J Rheumatol (1999) 1.89
Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity. EMBO J (1999) 1.88
Different cytokine profile and antigen-specificity repertoire in Helicobacter pylori-specific T cell clones from the antrum of chronic gastritis patients with or without peptic ulcer. Eur J Immunol (1997) 1.86
AME position statement on adrenal incidentaloma. Eur J Endocrinol (2011) 1.82
Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies. Infect Immun (1995) 1.79
Prevalence of human respiratory viruses in adults with acute respiratory tract infections in Beijing, 2005-2007. Clin Microbiol Infect (2009) 1.76
Interferon-gamma reduces macrophage-suppressive activity by inhibiting prostaglandin E2 release and inducing interleukin 1 production. J Immunol (1984) 1.75
Helicobacter pylori: host responses in peptic ulceration. Lancet (1993) 1.73
Diffuse axonal injury due to lateral head rotation in a rat model. J Neurosurg (2000) 1.63
Helicobacter pylori toxin VacA induces vacuole formation by acting in the cell cytosol. Mol Microbiol (1997) 1.60
Integration of telomere sequences with the draft human genome sequence. Nature (2001) 1.59
Bacterial protein toxins penetrate cells via a four-step mechanism. FEBS Lett (1994) 1.58
An amplified fragment length polymorphism map of the silkworm. Genetics (2001) 1.54
Two cases of Campylobacter mucosalis enteritis in children. J Clin Microbiol (1993) 1.52
Alterations in P2X and P2Y purinergic receptor expression in urinary bladder from normal cats and cats with interstitial cystitis. Am J Physiol Renal Physiol (2004) 1.50
Identification of the Helicobacter pylori VacA toxin domain active in the cell cytosol. Infect Immun (1998) 1.48
Antibody response to Helicobacter pylori CagA and heat-shock proteins in determining the risk of gastric cancer development. Dig Liver Dis (2001) 1.46
Characterization of genetically inactivated pertussis toxin mutants: candidates for a new vaccine against whooping cough. Infect Immun (1990) 1.44
Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila toll protein are essential for IL-1R signal transduction. J Biol Chem (1992) 1.44
Cytospray fixation of frozen intraoperative sections. Mod Pathol (1999) 1.42
American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and European Thyroid Association medical guidelines for clinical practice for the diagnosis and management of thyroid nodules: Executive Summary of recommendations. J Endocrinol Invest (2010) 1.40
American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and European Thyroid Association medical guidelines for clinical practice for the diagnosis and management of thyroid nodules. J Endocrinol Invest (2010) 1.39
Helicobacter pylori-specific CD4+ T-cell clones from peripheral blood and gastric biopsies. Infect Immun (1995) 1.39
Thyroid nodules: a review of current guidelines, practices, and prospects. Eur J Endocrinol (2008) 1.39
Effect of helicobacter pylori vacuolating toxin on maturation and extracellular release of procathepsin D and on epidermal growth factor degradation. J Biol Chem (1997) 1.38
Localization of ATP-gated P2X2 and P2X3 receptor immunoreactive nerves in rat taste buds. Neuroreport (1999) 1.37
Differentiation of motile and mesophilic Aeromonas strains into species by testing for a CAMP-like factor. J Clin Microbiol (1987) 1.37
Patterns of physical modes of contact between Campylobacter pylori and gastric epithelium: implications about the bacterial pathogenicity. Am J Gastroenterol (1989) 1.36
The Hsp60 protein of Helicobacter pylori: structure and immune response in patients with gastroduodenal diseases. Mol Microbiol (1993) 1.33
The subunit S1 is important for pertussis toxin secretion. J Biol Chem (1990) 1.33
Simple immunization protocol for high frequency production of soluble antigen-specific hybridomas. Hybridoma (1983) 1.33
A short synthetic peptide fragment of human interleukin 1 with immunostimulatory but not inflammatory activity. J Immunol (1986) 1.30
Metabolic, humoral, and cellular responses in adult volunteers immunized with the genetically inactivated pertussis toxin mutant PT-9K/129G. J Exp Med (1990) 1.30
Novel vaccine approaches. J Immunol (1996) 1.25
The African enigma: low prevalence of gastric atrophy, high prevalence of chronic inflammation in West African adults and children. Helicobacter (2001) 1.25
Cell specificity of Helicobacter pylori cytotoxin is determined by a short region in the polymorphic midregion. Infect Immun (2000) 1.23
Helicobacter pylori vacuolating toxin forms anion-selective channels in planar lipid bilayers: possible implications for the mechanism of cellular vacuolation. Biophys J (1999) 1.22
Specific and reversible inhibition by aphidicolin in the alpha-like DNA polymerase of plant cells. FEBS Lett (1980) 1.22
Staphylococcal alpha-toxin: a study of membrane penetration and pore formation. J Biol Chem (1989) 1.20
Lipid interaction of the 37-kDa and 58-kDa fragments of the Helicobacter pylori cytotoxin. Eur J Biochem (1995) 1.19
Towards deciphering the Helicobacter pylori cytotoxin. Mol Microbiol (1999) 1.18
Hippocampal circuitry complicates analysis of long-term potentiation in mossy fiber synapses. Hippocampus (1993) 1.17
Regulation of arachidonic acid metabolism in macrophages by immune and nonimmune interferons. J Immunol (1985) 1.17
3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin. J Mol Biol (1999) 1.16
Adult dogs receiving a rabies booster dose with a recombinant adenovirus expressing rabies virus glycoprotein develop high titers of neutralizing antibodies. Vaccine (2000) 1.15
Atrophic gastritis and intestinal metaplasia in Helicobacter pylori infection: the role of CagA status. Am J Gastroenterol (1998) 1.14
Voluntary exercise delays monogenetic obesity and overcomes reproductive dysfunction of the melanocortin-4 receptor knockout mouse. Biochem Biophys Res Commun (2005) 1.13
Interaction of the pertussis toxin peptide containing residues 30-42 with DR1 and the T-cell receptors of 12 human T-cell clones. Proc Natl Acad Sci U S A (1992) 1.12
Immunological detection of acetaldehyde-protein adducts in ethanol-treated carrot cells. Plant Physiol (1992) 1.11
Prescribing for inpatients with schizophrenia: an international multi-center comparative study. Pharmacopsychiatry (2003) 1.11
The murine interleukin 1 beta gene: structure and evolution. Nucleic Acids Res (1986) 1.09