Published in Cell on March 22, 1996
MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell (1998) 9.70
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A (2003) 9.14
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev (1999) 8.43
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc Natl Acad Sci U S A (2008) 6.53
A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature (2009) 5.65
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta. EMBO J (1999) 5.49
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell (2008) 5.11
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX. Proc Natl Acad Sci U S A (2002) 5.07
Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation. Mol Cell Biol (2004) 4.45
Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. Proc Natl Acad Sci U S A (1996) 3.78
The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. Proc Natl Acad Sci U S A (2000) 3.55
Statin treatment rescues FGFR3 skeletal dysplasia phenotypes. Nature (2014) 3.36
Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. Proc Natl Acad Sci U S A (1998) 3.27
TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage. J Cell Biol (2001) 3.22
Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3. Nat Genet (1997) 3.11
Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation. Cell (2008) 2.93
Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase. Mamm Genome (2002) 2.79
Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2. Proc Natl Acad Sci U S A (1998) 2.78
Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev (2002) 2.75
Growth of the normal skull vault and its alteration in craniosynostosis: insights from human genetics and experimental studies. J Anat (2005) 2.58
FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway. Cancer Cell (2007) 2.56
The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice. Proc Natl Acad Sci U S A (1998) 2.51
Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice. Proc Natl Acad Sci U S A (2003) 2.50
Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23. Endocrinology (2005) 2.46
FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev (2002) 2.41
Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. PLoS Genet (2008) 2.29
Targeted disruption of mouse long-chain acyl-CoA dehydrogenase gene reveals crucial roles for fatty acid oxidation. Proc Natl Acad Sci U S A (1998) 2.22
Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. Proc Natl Acad Sci U S A (1996) 2.22
A unique point mutation in the fibroblast growth factor receptor 3 gene (FGFR3) defines a new craniosynostosis syndrome. Am J Hum Genet (1997) 2.22
TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade. Proc Natl Acad Sci U S A (2009) 2.20
Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation. J Clin Invest (2000) 2.18
Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice. Proc Natl Acad Sci U S A (1997) 2.14
Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene. Genes Dev (1998) 2.12
Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts. J Cell Biol (2000) 2.08
Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning. EMBO J (1998) 2.07
A vital role for glycosphingolipid synthesis during development and differentiation. Proc Natl Acad Sci U S A (1999) 2.05
Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development. Genes Dev (1999) 2.05
Regional FMRP deficits and large repeat expansions into the full mutation range in a new Fragile X premutation mouse model. Gene (2007) 2.01
FGF signaling in the developing endochondral skeleton. Cytokine Growth Factor Rev (2005) 1.99
A genetic model of substrate deprivation therapy for a glycosphingolipid storage disorder. J Clin Invest (1999) 1.96
Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies. Biochemistry (2006) 1.96
Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects. Proc Natl Acad Sci U S A (1999) 1.95
FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway. Genes Dev (1999) 1.94
Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2. Proc Natl Acad Sci U S A (1998) 1.94
Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice. Proc Natl Acad Sci U S A (1999) 1.93
Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation. Am J Hum Genet (2004) 1.92
Development of the endochondral skeleton. Cold Spring Harb Perspect Biol (2013) 1.89
Genomic screening of fibroblast growth-factor receptor 2 reveals a wide spectrum of mutations in patients with syndromic craniosynostosis. Am J Hum Genet (2002) 1.88
Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype. Genes Dev (2004) 1.88
SIRT6 deficiency results in severe hypoglycemia by enhancing both basal and insulin-stimulated glucose uptake in mice. J Biol Chem (2010) 1.86
Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway. Proc Natl Acad Sci U S A (2000) 1.82
The Fibroblast Growth Factor signaling pathway. Wiley Interdiscip Rev Dev Biol (2015) 1.82
Mammalian DNA topoisomerase IIIalpha is essential in early embryogenesis. Proc Natl Acad Sci U S A (1998) 1.76
A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3. Proc Natl Acad Sci U S A (1999) 1.75
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation. Genes Dev (1999) 1.74
Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality. Mol Cell Biol (2005) 1.71
Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress. Genes Dev (2000) 1.70
An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis. Nat Immunol (2005) 1.69
Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality. Mol Cell Biol (2002) 1.66
Compensation by fibroblast growth factor 1 (FGF1) does not account for the mild phenotypic defects observed in FGF2 null mice. Mol Cell Biol (2000) 1.65
The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis. J Exp Med (2000) 1.63
Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis. J Clin Invest (1999) 1.62
Uncompensated polyuria in a mouse model of Bartter's syndrome. Proc Natl Acad Sci U S A (2000) 1.59
Alternative Gnas gene products have opposite effects on glucose and lipid metabolism. Proc Natl Acad Sci U S A (2005) 1.59
Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice. J Clin Invest (1998) 1.59
Distinct missense mutations of the FGFR3 lys650 codon modulate receptor kinase activation and the severity of the skeletal dysplasia phenotype. Am J Hum Genet (2000) 1.58
An essential role for FGF receptor signaling in lens development. Semin Cell Dev Biol (2006) 1.58
Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol (2008) 1.58
Innate immune response to encephalomyocarditis virus infection mediated by CD1d. Immunology (2003) 1.57
Fibroblast growth factor regulation of neovascularization. Curr Opin Hematol (2008) 1.56
A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes. Proc Natl Acad Sci U S A (2001) 1.56
An essential role for c-FLIP in the efficient development of mature T lymphocytes. J Exp Med (2005) 1.55
Regulation of chondrogenesis and chondrocyte differentiation by stress. J Clin Invest (2008) 1.53
The role of fibroblast growth factors in tumor growth. Curr Cancer Drug Targets (2009) 1.52
Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation. Genes Dev (2003) 1.51
p38 MAP kinase signalling is required for hypertrophic chondrocyte differentiation. Biochem J (2004) 1.45
Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate. J Cell Biol (2004) 1.45
Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia. Proc Natl Acad Sci U S A (2003) 1.44
The gene for cherubism maps to chromosome 4p16.3. Am J Hum Genet (1999) 1.43
Identification of the control region for tissue-specific imprinting of the stimulatory G protein alpha-subunit. Proc Natl Acad Sci U S A (2005) 1.43
Multiple Phylogenetically Distinct Events Shaped the Evolution of Limb Skeletal Morphologies Associated with Bipedalism in the Jerboas. Curr Biol (2015) 1.42
Positional cloning of the gene LIMBIN responsible for bovine chondrodysplastic dwarfism. Proc Natl Acad Sci U S A (2002) 1.42
FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development. Neural Dev (2008) 1.40
Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development. J Clin Invest (2007) 1.39
A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation. J Cell Biol (2003) 1.39
Jmjd1a demethylase-regulated histone modification is essential for cAMP-response element modulator-regulated gene expression and spermatogenesis. J Biol Chem (2009) 1.38
The transmembrane mutation G380R in fibroblast growth factor receptor 3 uncouples ligand-mediated receptor activation from down-regulation. Mol Cell Biol (2000) 1.38
Sixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasias. Hum Mutat (2011) 1.35
A novel skeletal dysplasia with developmental delay and acanthosis nigricans is caused by a Lys650Met mutation in the fibroblast growth factor receptor 3 gene. Am J Hum Genet (1999) 1.35
Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol (2006) 1.35
Parathyroid hormone-related peptide (PTHrP)-dependent and -independent effects of transforming growth factor beta (TGF-beta) on endochondral bone formation. J Cell Biol (1999) 1.35
COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling. Cereb Cortex (2007) 1.33
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis. Proc Natl Acad Sci U S A (1999) 1.33
A novel mutation in FGFR3 causes camptodactyly, tall stature, and hearing loss (CATSHL) syndrome. Am J Hum Genet (2006) 1.31
Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid. Proc Natl Acad Sci U S A (2012) 1.30
Increased calvaria cell differentiation and bone matrix formation induced by fibroblast growth factor receptor 2 mutations in Apert syndrome. J Clin Invest (1998) 1.30
FGFR3 and FGFR4 do not mediate renal effects of FGF23. J Am Soc Nephrol (2008) 1.28
Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3. EMBO J (2011) 1.27
Sulfation of chondroitin sulfate proteoglycans is necessary for proper Indian hedgehog signaling in the developing growth plate. Development (2009) 1.27
FGF signaling is strictly required to maintain early telencephalic precursor cell survival. Development (2009) 1.26
Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. Proc Natl Acad Sci U S A (1972) 83.88
The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science (1998) 39.86
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79
Functional annotation of a full-length mouse cDNA collection. Nature (2001) 23.61
Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell (1983) 17.87
Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation. Proc Natl Acad Sci U S A (1984) 17.51
EK2 derivatives of bacteriophage lambda useful in the cloning of DNA from higher organisms: the lambdagtWES system. Science (1977) 13.24
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell (1995) 12.39
Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proc Natl Acad Sci U S A (1982) 10.50
Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell (1996) 10.40
The sequence of the chromosomal mouse beta-globin major gene: homologies in capping, splicing and poly(A) sites. Cell (1978) 9.73
Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene. Proc Natl Acad Sci U S A (1979) 9.31
Structure of the human immunoglobulin mu locus: characterization of embryonic and rearranged J and D genes. Cell (1981) 9.09
Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell (1991) 8.99
Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments. Cell (1980) 8.77
The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma. Cell (1983) 8.54
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. Nat Genet (1999) 8.17
The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes. Cell (1979) 8.11
In vitro synthesis of DNA complementary to purified rabbit globin mRNA (RNA-dependent DNA polymerase-reticulocyte-hemoglobin-density gradient centrifugation-oligo(dT) primer). Proc Natl Acad Sci U S A (1972) 7.89
Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell (1988) 7.50
The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity (1998) 7.35
The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes. J Biol Chem (1981) 7.26
Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes. Cell (1984) 6.71
A kappa-immunoglobulin gene is formed by site-specific recombination without further somatic mutation. Nature (1979) 6.54
Protein synthesis directed by encephalomyocarditis virus RNA: properties of a transfer RNA-dependent system. Proc Natl Acad Sci U S A (1971) 6.52
c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities. Cell (1988) 6.24
Translocations among antibody genes in human cancer. Science (1983) 6.20
The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor. Proc Natl Acad Sci U S A (1978) 6.20
The complete sequence of a chromosomal mouse alpha--globin gene reveals elements conserved throughout vertebrate evolution. Cell (1979) 6.05
Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev (1996) 6.01
RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell (1995) 5.73
Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in Burkitt lymphoma. Cell (1984) 5.61
Protein synthesis directed by encephalomyocarditis virus RNA. II. The in vitro synthesis of high molecular weight proteins and elements of the viral capsid. Biochem Biophys Res Commun (1971) 5.60
Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes. J Biol Chem (1980) 5.59
Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo. Cell (1987) 5.57
Stat5a is mandatory for adult mammary gland development and lactogenesis. Genes Dev (1997) 5.57
Purification and properties of biologically active messenger RNA for a myeloma light chain. Proc Natl Acad Sci U S A (1972) 5.28
Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences. Proc Natl Acad Sci U S A (1977) 5.28
RNA codewords and protein synthesis, VII. On the general nature of the RNA code. Proc Natl Acad Sci U S A (1965) 5.17
Antibody diversity. Science (1978) 5.06
Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies. Psychopharmacology (Berl) (1997) 5.03
Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell (1998) 4.95
The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell (1990) 4.91
Cre-mediated gene deletion in the mammary gland. Nucleic Acids Res (1997) 4.89
The arrangement and rearrangement of antibody genes. Nature (1979) 4.88
Clustered arrangement of immunoglobulin lambda constant region genes in man. Nature (1981) 4.87
Splicing and the formation of stable RNA. Cell (1979) 4.71
TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell (2001) 4.60
Functional role for c-myc in mitogenic response to platelet-derived growth factor. Nature (1984) 4.56
The kit ligand: a cell surface molecule altered in steel mutant fibroblasts. Cell (1990) 4.43
Butyric acid, a potent inducer of erythroid differentiation in cultured erythroleukemic cells. Cell (1975) 4.32
Processed genes: a dispersed human immunoglobulin gene bearing evidence of RNA-type processing. Nature (1982) 4.14
Human immunoglobulin heavy chain genes map to a region of translocations in malignant B lymphocytes. Science (1982) 4.05
Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene. Proc Natl Acad Sci U S A (1978) 4.02
Globin messenger-RNA induction during erythroid differentiation of cultured leukemia cells. Proc Natl Acad Sci U S A (1972) 4.02
Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev (1994) 3.97
A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. Neuron (2000) 3.93
Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality. Nat Genet (1998) 3.89
Multiple related immunoglobulin variable-region genes identified by cloning and sequence analysis. Proc Natl Acad Sci U S A (1978) 3.88
Purification and cloning of a mouse ribosomal gene fragment in coliphage lambda. Gene (1977) 3.79
An eosinophil-dependent mechanism for the antitumor effect of interleukin-4. Science (1992) 3.78
Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. Proc Natl Acad Sci U S A (1996) 3.78
Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells. Proc Natl Acad Sci U S A (1981) 3.73
Consequences of widespread deregulation of the c-myc gene in transgenic mice: multiple neoplasms and normal development. Cell (1986) 3.70
Activation and somatic mutation of the translocated c-myc gene in burkitt lymphoma cells. Cell (1984) 3.66
Human immunoglobulin kappa light-chain genes are deleted or rearranged in lambda-producing B cells. Nature (1981) 3.64
Antibodies to human c-myc oncogene product: evidence of an evolutionarily conserved protein induced during cell proliferation. Science (1984) 3.63
Structural conservation in prokaryotic and eukaryotic potassium channels. Science (1998) 3.61
Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant. Cell (1991) 3.60
The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo. Cell (1996) 3.55
Murine interleukin-4 displays potent anti-tumor activity in vivo. Cell (1989) 3.43
High capacity gel preparative electrophoresis for purification of fragments of genomic DNA. Anal Biochem (1978) 3.42
Evolution of human immunoglobulin kappa J region genes. J Biol Chem (1982) 3.41
Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells. Mol Cell Biol (1992) 3.41
Initiation of protein synthesis II. A convenient assay for the ribosome-dependent synthesis of N-formyl-C14-methionylpuromycin. Biochem Biophys Res Commun (1966) 3.39
Transcription of mouse kappa chain genes: implications for allelic exclusion. Proc Natl Acad Sci U S A (1980) 3.38
Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature. Cell (2001) 3.37
Nuclear localization and DNA binding properties of a protein expressed by human c-myc oncogene. Science (1984) 3.24
Unusual alpha-globin-like gene that has cleanly lost both globin intervening sequences. Proc Natl Acad Sci U S A (1980) 3.19
Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase. J Biol Chem (1999) 3.17
Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo. Nature (1998) 3.16
Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1. Cell (1997) 3.10
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse. Nature (1985) 3.05
Differentiation in erythroleukemic cells and their somatic hybrids. Proc Natl Acad Sci U S A (1975) 3.05
Human immunoglobulin D segments encoded in tandem multigenic families. Nature (1981) 2.99
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation. Nature (1997) 2.98
Casein kinase II alpha transgene-induced murine lymphoma: relation to theileriosis in cattle. Science (1995) 2.92
Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins. J Clin Invest (1983) 2.91
Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction. Development (1998) 2.90
Multicolour spectral karyotyping of mouse chromosomes. Nat Genet (1996) 2.90
A novel class of eukaryotic zinc-binding proteins is required for disease resistance signaling in barley and development in C. elegans. Cell (1999) 2.86
IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice. Cell (1990) 2.86
RNA codewords and protein synthesis, 8. Nucleotide sequences of synonym codons for arginine, valine, cysteine, and alanine. Proc Natl Acad Sci U S A (1965) 2.86
Parental-specific methylation of an imprinted transgene is established during gametogenesis and progressively changes during embryogenesis. Cell (1991) 2.85
Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Nat Cell Biol (2000) 2.81
Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. II. Identification of cAMP and glucocorticoid regulatory domains. J Biol Chem (1986) 2.80
The cytomegalovirus enhancer: a pan-active control element in transgenic mice. Mol Cell Biol (1990) 2.80