Published in Mol Pharmacol on April 01, 1996
Stepping backward to improve assessment of PCB congener toxicities. Environ Health Perspect (1998) 1.98
In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens. Environ Health Perspect (2008) 1.82
Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating. PLoS Biol (2009) 1.77
Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity. Pharmacol Ther (2009) 1.63
Perinatal exposure to a noncoplanar polychlorinated biphenyl alters tonotopy, receptive fields, and plasticity in rat primary auditory cortex. Proc Natl Acad Sci U S A (2007) 1.43
In situ activation of the type 2 ryanodine receptor in pancreatic beta cells requires cAMP-dependent phosphorylation. Proc Natl Acad Sci U S A (1998) 1.21
PCB-95 promotes dendritic growth via ryanodine receptor-dependent mechanisms. Environ Health Perspect (2012) 1.12
Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2. Chem Res Toxicol (2009) 1.11
2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) is enantioselectively oxidized to hydroxylated metabolites by rat liver microsomes. Chem Res Toxicol (2011) 1.07
Para- and ortho-substitutions are key determinants of polybrominated diphenyl ether activity toward ryanodine receptors and neurotoxicity. Environ Health Perspect (2010) 1.03
Examination of the estrogenicity of 2,4,6,2',6'-pentachlorobiphenyl (PCB 104), its hydroxylated metabolite 2,4,6,2',6'-pentachloro-4-biphenylol (HO-PCB 104), and a further chlorinated derivative, 2,4,6,2',4',6'-hexachlorobiphenyl (PCB 155). Environ Health Perspect (1997) 1.00
Neuronal connectivity as a convergent target of gene × environment interactions that confer risk for Autism Spectrum Disorders. Neurotoxicol Teratol (2012) 0.95
Simplified cyclic analogues of bastadin-5. Structure-activity relationships for modulation of the RyR1/FKBP12 Ca2+ channel complex. J Med Chem (2006) 0.92
Excitatory and inhibitory synaptic transmission is differentially influenced by two ortho-substituted polychlorinated biphenyls in the hippocampal slice preparation. Toxicol Appl Pharmacol (2009) 0.90
Stimulation of contraction of pregnant rat uterus in vitro by non-dechlorinated and microbially dechlorinated mixtures of polychlorinated biphenyls. Environ Health Perspect (2001) 0.82
Ryanodine receptor type 1 (RyR1) possessing malignant hyperthermia mutation R615C exhibits heightened sensitivity to dysregulation by non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95). Neurotoxicology (2006) 0.80
Accumulation of polychlorinated biphenyls in adipocytes: selective targeting to lipid droplets and role of caveolin-1. PLoS One (2012) 0.79
TLR4 signaling is involved in brain vascular toxicity of PCB153 bound to nanoparticles. PLoS One (2013) 0.76
Non-Dioxin-Like Polychlorinated Biphenyls Inhibit G-Protein Coupled Receptor-Mediated Ca2+ Signaling by Blocking Store-Operated Ca2+ Entry. PLoS One (2016) 0.76
Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity. Neurotoxicology (2016) 0.75
Quantification of Polychlorinated Biphenyls and Polybrominated Diphenyl Ethers in Commercial Cows' Milk from California by Gas Chromatography-Triple Quadruple Mass Spectrometry. PLoS One (2017) 0.75
Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor. Nature (1996) 4.42
Xestospongins: potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor. Neuron (1997) 3.27
Ca2+-activated ryanodine binding: mechanisms of sensitivity and intensity modulation by Mg2+, caffeine, and adenine nucleotides. Mol Pharmacol (1987) 2.31
The calcium-ryanodine receptor complex of skeletal and cardiac muscle. Biochem Biophys Res Commun (1985) 1.96
Calcium-ryanodine receptor complex. Solubilization and partial characterization from skeletal muscle junctional sarcoplasmic reticulum vesicles. J Biol Chem (1986) 1.83
Ryanodine stabilizes multiple conformational states of the skeletal muscle calcium release channel. J Biol Chem (1992) 1.80
Involvement of multiple intracellular release channels in calcium sparks of skeletal muscle. Proc Natl Acad Sci U S A (2000) 1.78
Divergent functional properties of ryanodine receptor types 1 and 3 expressed in a myogenic cell line. Biophys J (2000) 1.69
Autism-specific maternal autoantibodies recognize critical proteins in developing brain. Transl Psychiatry (2013) 1.46
Perinatal exposure to a noncoplanar polychlorinated biphenyl alters tonotopy, receptive fields, and plasticity in rat primary auditory cortex. Proc Natl Acad Sci U S A (2007) 1.43
Dyspedic mouse skeletal muscle expresses major elements of the triadic junction but lacks detectable ryanodine receptor protein and function. J Biol Chem (1997) 1.39
Ortho-substituted polychlorinated biphenyls alter microsomal calcium transport by direct interaction with ryanodine receptors of mammalian brain. J Biol Chem (1997) 1.37
Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca(2+) release channel/ryanodine receptors. FEBS Lett (2000) 1.36
Transmembrane redox sensor of ryanodine receptor complex. J Biol Chem (2000) 1.28
Novel modulators of skeletal muscle FKBP12/calcium channel complex from Ianthella basta. Role of FKBP12 in channel gating. J Biol Chem (1994) 1.27
Gating of store-operated channels by conformational coupling to ryanodine receptors. Mol Cell (2000) 1.25
Comparison of [3H]ryanodine receptors and Ca++ release from rat cardiac and rabbit skeletal muscle sarcoplasmic reticulum. J Pharmacol Exp Ther (1991) 1.19
A transgenic myogenic cell line lacking ryanodine receptor protein for homologous expression studies: reconstitution of Ry1R protein and function. J Cell Biol (1998) 1.19
Ryanodine induces persistent inactivation of the Ca2+ release channel from skeletal muscle sarcoplasmic reticulum. Mol Pharmacol (1992) 1.14
Sparks and puffs in oligodendrocyte progenitors: cross talk between ryanodine receptors and inositol trisphosphate receptors. J Neurosci (2001) 1.12
HSV-1 amplicon vectors are a highly efficient gene delivery system for skeletal muscle myoblasts and myotubes. Am J Physiol Cell Physiol (2000) 1.11
Symposium overview: toxicity of non-coplanar PCBs. Toxicol Sci (1998) 1.11
ortho-substituted PCB95 alters intracellular calcium signaling and causes cellular acidification in PC12 cells by an immunophilin-dependent mechanism. J Neurochem (2001) 1.09
Bastadin 10 stabilizes the open conformation of the ryanodine-sensitive Ca(2+) channel in an FKBP12-dependent manner. J Biol Chem (1999) 1.04
Type 1 and type 3 ryanodine receptors generate different Ca(2+) release event activity in both intact and permeabilized myotubes. Biophys J (2001) 1.01
Long-term effects of developmental exposure to 2,2',3,5',6-pentachlorobiphenyl (PCB 95) on locomotor activity, spatial learning and memory and brain ryanodine binding. Neurotoxicology (1997) 1.01
Structural aspects of ryanodine action and selectivity. J Med Chem (1987) 1.01
Direct evidence for the existence and functional role of hyperreactive sulfhydryls on the ryanodine receptor-triadin complex selectively labeled by the coumarin maleimide 7-diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin. Mol Pharmacol (1994) 1.00
Ortho-substituted 2,2',3,5',6-pentachlorobiphenyl (PCB 95) alters rat hippocampal ryanodine receptors and neuroplasticity in vitro: evidence for altered hippocampal function. Neurotoxicology (1997) 0.99
Noncoplanar PCB 95 alters microsomal calcium transport by an immunophilin FKBP12-dependent mechanism. Mol Pharmacol (1997) 0.99
Ryanodine receptor point mutant E4032A reveals an allosteric interaction with ryanodine. Proc Natl Acad Sci U S A (2001) 0.98
Molecular interaction between ryanodine receptor and glycoprotein triadin involves redox cycling of functionally important hyperreactive sulfhydryls. J Biol Chem (1994) 0.97
Iron(II) is a modulator of ryanodine-sensitive calcium channels of cardiac muscle sarcoplasmic reticulum. Toxicol Appl Pharmacol (1995) 0.96
Mechanism of anthraquinone-induced calcium release from skeletal muscle sarcoplasmic reticulum. J Biol Chem (1988) 0.96
Inositol-1,4,5-trisphosphate receptor-mediated Ca mobilization is not required for cerebellar long-term depression in reduced preparations. J Neurophysiol (1998) 0.94
Ryanodine receptor type III (Ry3R) identification in mouse parotid acini. Properties and modulation of [3H]ryanodine-binding sites. J Biol Chem (1997) 0.93
Prolonged exercise reduces Ca2+ release in rat skeletal muscle sarcoplasmic reticulum. Pflugers Arch (1993) 0.92
Bastadin 20 and bastadin O-sulfate esters from Ianthella basta: novel modulators of the Ry1R FKBP12 receptor complex. J Nat Prod (1996) 0.91
Discrimination of multiple binding sites for antagonists of the calcium release channel complex of skeletal and cardiac sarcoplasmic reticulum. J Pharmacol Exp Ther (1992) 0.91
Partial characterization of specific cantharidin binding sites in mouse tissues. Mol Pharmacol (1988) 0.90
Site-selective modification of hyperreactive cysteines of ryanodine receptor complex by quinones. Mol Pharmacol (1999) 0.89
Pharmacological characterization of the specific binding of [3H]ryanodine to rat brain microsomal membranes. Brain Res (1991) 0.85
Regulation of [3H]perhydrohistrionicotoxin binding to Torpedo ocellata electroplax by effectors of the acetylcholine receptor. J Biol Chem (1981) 0.84
Mechanisms of delta-hexachlorocyclohexane toxicity: I. Relationship between altered ventricular myocyte contractility and ryanodine receptor function. J Pharmacol Exp Ther (1999) 0.83
Complex pharmacology of malignant hyperthermia. Anesthesiology (1996) 0.83
Rose bengal activates the Ca2+ release channel from skeletal muscle sarcoplasmic reticulum. Arch Biochem Biophys (1992) 0.81
Photooxidation of skeletal muscle sarcoplasmic reticulum induces rapid calcium release. Arch Biochem Biophys (1992) 0.81
Reconstitution of N1-methylnicotinamide and p-aminohippuric acid transport in phospholipid vesicles with a protein fraction isolated from dog kidney membranes. Mol Pharmacol (1979) 0.79
The delta isomer of hexachlorocyclohexane induces rapid release of the myo-inositol-1,4,5-trisphosphate-sensitive Ca2+ store and blocks capacitative Ca2+ entry in rat basophilic leukemia cells. Mol Pharmacol (1995) 0.78
Porphyrin induced calcium release from skeletal muscle sarcoplasmic reticulum. Arch Biochem Biophys (1993) 0.78
Regulation of inositol 1,4,5-trisphosphate receptors in rat basophilic leukemia cells. I. Multiple conformational states of the receptor in a microsomal preparation. Biochim Biophys Acta (1993) 0.78
Mechanisms of delta-hexachlorocyclohexane toxicity: II. Evidence for Ca2+-dependent K+-selective ionophore activity. J Pharmacol Exp Ther (1999) 0.75
Characterization of [(3)H]ryanodine binding sites in mammalian lung. Arch Biochem Biophys (2000) 0.75
Solubilization and separation of Ca2+-ATPase from the Ca2+-ryanodine receptor complex. Biochem Biophys Res Commun (1986) 0.75
Antithetical actions of mitoxantrone and doxorubicin on ryanodine-sensitive Ca++ release channels of rat cardiac sarcoplasmic reticulum: evidence for a competitive mechanism. J Pharmacol Exp Ther (1994) 0.75
Regulation of inositol 1,4,5-trisphosphate receptors in rat basophilic leukemia cells. II. Modulation of the receptor in permeabilized cells by the cytosolic compartment. Biochim Biophys Acta (1993) 0.75
Ryanodine and dihydropyridine binding patterns and ryanodine receptor mRNA levels in myopathic hamster heart. Am J Physiol (1994) 0.75