Published in J Biol Chem on June 07, 1996
VDAC structure, selectivity, and dynamics. Biochim Biophys Acta (2012) 1.33
Minireview: on the structure and gating mechanism of the mitochondrial channel, VDAC. J Bioenerg Biomembr (1997) 1.22
Characterization of a bifunctional enzyme fusion of trehalose-6-phosphate synthetase and trehalose-6-phosphate phosphatase of Escherichia coli. Appl Environ Microbiol (2000) 1.20
The evolutionary history of mitochondrial porins. BMC Evol Biol (2007) 1.18
The 3D structures of VDAC represent a native conformation. Trends Biochem Sci (2010) 1.13
Voltage-dependent anion channel 1-based peptides interact with Bcl-2 to prevent antiapoptotic activity. J Biol Chem (2009) 1.13
Affixing N-terminal α-helix to the wall of the voltage-dependent anion channel does not prevent its voltage gating. J Biol Chem (2012) 1.13
The electrostatics of VDAC: implications for selectivity and gating. J Mol Biol (2009) 1.11
β-Barrel mobility underlies closure of the voltage-dependent anion channel. Structure (2012) 1.04
Structure of the voltage dependent anion channel: state of the art. J Bioenerg Biomembr (2008) 1.01
Functional model of metabolite gating by human voltage-dependent anion channel 2. Biochemistry (2011) 1.00
Reflections on VDAC as a voltage-gated channel and a mitochondrial regulator. J Bioenerg Biomembr (2008) 0.97
Flexibility of the N-terminal mVDAC1 segment controls the channel's gating behavior. PLoS One (2012) 0.82
Solid-state NMR, electrophysiology and molecular dynamics characterization of human VDAC2. J Biomol NMR (2014) 0.82
Revisiting trends on mitochondrial mega-channels for the import of proteins and nucleic acids. J Bioenerg Biomembr (2016) 0.82
Deletion variants of Neurospora mitochondrial porin: electrophysiological and spectroscopic analysis. Biophys J (2006) 0.81
Concentration dependent ion selectivity in VDAC: a molecular dynamics simulation study. PLoS One (2011) 0.80
Current state of theoretical and experimental studies of the voltage-dependent anion channel (VDAC). Biochim Biophys Acta (2016) 0.79
N-helix and Cysteines Inter-regulate Human Mitochondrial VDAC-2 Function and Biochemistry. J Biol Chem (2015) 0.78
Magic angle spinning nuclear magnetic resonance characterization of voltage-dependent anion channel gating in two-dimensional lipid crystalline bilayers. Biochemistry (2015) 0.78
Functional characterization of the conserved "GLK" motif in mitochondrial porin from Neurospora crassa. J Bioenerg Biomembr (2000) 0.78
Two-step folding of recombinant mitochondrial porin in detergent. Biophys J (2007) 0.78
Characterization of channel-forming activity in muscle biopsy from a porin-deficient human patient. J Bioenerg Biomembr (2000) 0.75
VDAC2-specific cellular functions and the underlying structure. Biochim Biophys Acta (2016) 0.75
Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria. Nature (1989) 5.19
Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins. Nature (1990) 5.12
Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis. Nature (1989) 4.57
Formation of large, ion-permeable membrane channels by the matrix protein (porin) of Escherichia coli. Biochim Biophys Acta (1978) 4.55
The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J (1999) 4.05
Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae. J Biol Chem (1998) 3.96
Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli. Biochemistry (1999) 3.88
Ionic selectivity of pores formed by the matrix protein (porin) of Escherichia coli. Biochim Biophys Acta (1979) 3.72
Mitochondrial protein import. Biochim Biophys Acta (1989) 3.66
Electrical capacity of black lipid films and of lipid bilayers made from monolayers. Biochim Biophys Acta (1975) 3.65
Properties of the large ion-permeable pores formed from protein F of Pseudomonas aeruginosa in lipid bilayer membranes. Biochim Biophys Acta (1981) 3.65
Transport of proteins into mitochondria: translocational intermediates spanning contact sites between outer and inner membranes. Cell (1985) 3.55
Mitochondria-targeted green fluorescent proteins: convenient tools for the study of organelle biogenesis in Saccharomyces cerevisiae. Yeast (2000) 3.52
The role of Hsp70 in conferring unidirectionality on protein translocation into mitochondria. Science (1994) 3.26
Mitochondrial Hsp70/MIM44 complex facilitates protein import. Nature (1994) 3.08
Protein sorting to mitochondria: evolutionary conservations of folding and assembly. Science (1990) 3.07
A fraction of yeast Cu,Zn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. A physiological role for SOD1 in guarding against mitochondrial oxidative damage. J Biol Chem (2001) 3.01
Three pure chaperone proteins of Escherichia coli--SecB, trigger factor and GroEL--form soluble complexes with precursor proteins in vitro. EMBO J (1989) 2.89
Ion selectivity of gram-negative bacterial porins. J Bacteriol (1985) 2.87
The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondria. Cell (1996) 2.80
Outer membrane protein P of Pseudomonas aeruginosa: regulation by phosphate deficiency and formation of small anion-specific channels in lipid bilayer membranes. J Bacteriol (1982) 2.73
Requirement of a membrane potential for the posttranslational transfer of proteins into mitochondria. Eur J Biochem (1982) 2.71
Yeast mitochondrial F1F0-ATP synthase exists as a dimer: identification of three dimer-specific subunits. EMBO J (1998) 2.67
The preprotein translocation channel of the outer membrane of mitochondria. Cell (1998) 2.65
Mitochondrial protein import: nucleoside triphosphates are involved in conferring import-competence to precursors. Cell (1987) 2.61
Mitochondrial protein import: identification of processing peptidase and of PEP, a processing enhancing protein. Cell (1988) 2.57
Reversible electrical breakdown of lipid bilayer membranes: a charge-pulse relaxation study. J Membr Biol (1979) 2.52
Cyclosporin A-binding protein (cyclophilin) of Neurospora crassa. One gene codes for both the cytosolic and mitochondrial forms. J Biol Chem (1988) 2.43
MITOP, the mitochondrial proteome database: 2000 update. Nucleic Acids Res (2000) 2.43
ProOmpA is stabilized for membrane translocation by either purified E. coli trigger factor or canine signal recognition particle. Cell (1988) 2.42
Sensitivity to cyclosporin A is mediated by cyclophilin in Neurospora crassa and Saccharomyces cerevisiae. Nature (1990) 2.37
The resealing process of lipid bilayers after reversible electrical breakdown. Biochim Biophys Acta (1981) 2.35
Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondria. Mol Cell Biol (1999) 2.34
SecA protein, a peripheral protein of the Escherichia coli plasma membrane, is essential for the functional binding and translocation of proOmpA. EMBO J (1989) 2.33
Transport of F1-ATPase subunit beta into mitochondria depends on both a membrane potential and nucleoside triphosphates. FEBS Lett (1986) 2.33
Protein folding in the cell: the role of molecular chaperones Hsp70 and Hsp60. Annu Rev Biophys Biomol Struct (1992) 2.31
The mitochondrial protein import apparatus. Annu Rev Biochem (1990) 2.31
The repeat domain of Escherichia coli haemolysin (HlyA) is responsible for its Ca2+-dependent binding to erythrocytes. Mol Gen Genet (1988) 2.29
A mitochondrial ferredoxin is essential for biogenesis of cellular iron-sulfur proteins. Proc Natl Acad Sci U S A (2000) 2.27
Voltage-dependent depolarization of bacterial membranes and artificial lipid bilayers by the peptide antibiotic nisin. Arch Microbiol (1987) 2.26
Successive translocation into and out of the mitochondrial matrix: targeting of proteins to the intermembrane space by a bipartite signal peptide. Cell (1987) 2.24
The ABC transporter Atm1p is required for mitochondrial iron homeostasis. FEBS Lett (1997) 2.21
Transport into mitochondria and intramitochondrial sorting of the Fe/S protein of ubiquinol-cytochrome c reductase. Cell (1986) 2.21
An essential function of the mitochondrial sulfhydryl oxidase Erv1p/ALR in the maturation of cytosolic Fe/S proteins. EMBO Rep (2001) 2.19
Transport of proteins into mitochondria: a potassium diffusion potential is able to drive the import of ADP/ATP carrier. EMBO J (1985) 2.19
MOM19, an import receptor for mitochondrial precursor proteins. Cell (1989) 2.18
Molecular mechanisms of cytochrome c biogenesis: three distinct systems. Mol Microbiol (1998) 2.15
Mdj1p, a novel chaperone of the DnaJ family, is involved in mitochondrial biogenesis and protein folding. Cell (1994) 2.12
Mode of action of the staphylococcinlike peptide Pep 5: voltage-dependent depolarization of bacterial and artificial membranes. J Bacteriol (1988) 2.10
Determination of ion permeability through the channels made of porins from the outer membrane of Salmonella typhimurium in lipid bilayer membranes. J Membr Biol (1980) 2.07
Isolation and subfractionation of mitochondria from the yeast Saccharomyces cerevisiae. Methods Cell Biol (2001) 2.03
Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22. Nature (1996) 2.03
Pore formation by LamB of Escherichia coli in lipid bilayer membranes. J Bacteriol (1986) 2.02
Role of Tim23 as voltage sensor and presequence receptor in protein import into mitochondria. Cell (1996) 2.02
Porin from bacterial and mitochondrial outer membranes. CRC Crit Rev Biochem (1985) 2.02
Distinct steps in the import of ADP/ATP carrier into mitochondria. J Biol Chem (1987) 2.02
Assembly of cytochrome c. Apocytochrome c is bound to specific sites on mitochondria before its conversion to holocytochrome c. Eur J Biochem (1981) 1.97
Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space. Cell (1992) 1.96
A mitochondrial import receptor for the ADP/ATP carrier. Cell (1990) 1.95
The cytochrome bc1 and cytochrome c oxidase complexes associate to form a single supracomplex in yeast mitochondria. J Biol Chem (2000) 1.93
Oxa1p acts as a general membrane insertion machinery for proteins encoded by mitochondrial DNA. EMBO J (2001) 1.91
Identification of a mitochondrial receptor complex required for recognition and membrane insertion of precursor proteins. Nature (1990) 1.90
Conversion of the FhuA transport protein into a diffusion channel through the outer membrane of Escherichia coli. EMBO J (1993) 1.89
ATP synthase of yeast mitochondria. Isolation of subunit j and disruption of the ATP18 gene. J Biol Chem (1999) 1.87
Isolation of Neisseria meningitidis mutants deficient in class 1 (porA) and class 3 (porB) outer membrane proteins. Infect Immun (1990) 1.87
Receptor for bacteriophage lambda of Escherichia coli forms larger pores in black lipid membranes than the matrix protein (porin). J Bacteriol (1979) 1.86
Cloning of the mspA gene encoding a porin from Mycobacterium smegmatis. Mol Microbiol (1999) 1.84
Translocation arrest by reversible folding of a precursor protein imported into mitochondria. A means to quantitate translocation contact sites. J Cell Biol (1989) 1.84
Relaxation studies of ion transport systems in lipid bilayer membranes. Q Rev Biophys (1981) 1.81
Carrier protein import into mitochondria mediated by the intermembrane proteins Tim10/Mrs11 and Tim12/Mrs5. Nature (1998) 1.81
Molecular chaperones cooperate with PIM1 protease in the degradation of misfolded proteins in mitochondria. EMBO J (1994) 1.80
Peptide nucleic acid delivery to human mitochondria. Gene Ther (1999) 1.77
Oxa1p, an essential component of the N-tail protein export machinery in mitochondria. Proc Natl Acad Sci U S A (1998) 1.76
A mutation of the mitochondrial ABC transporter Sta1 leads to dwarfism and chlorosis in the Arabidopsis mutant starik. Plant Cell (2001) 1.76
Cell-free synthesis of the mitochondrial ADP/ATP carrier protein of Neurospora crassa. Eur J Biochem (1979) 1.75
Internal targeting signal of the BCS1 protein: a novel mechanism of import into mitochondria. EMBO J (1996) 1.74
A dynamic model of the mitochondrial protein import machinery. Cell (1992) 1.74
Membrane protein degradation by AAA proteases in mitochondria: extraction of substrates from either membrane surface. Mol Cell (2000) 1.73
The processing peptidase of yeast mitochondria: the two co-operating components MPP and PEP are structurally related. EMBO J (1988) 1.73
Processing peptidase of Neurospora mitochondria. Two-step cleavage of imported ATPase subunit 9. Eur J Biochem (1984) 1.73
The TOM core complex: the general protein import pore of the outer membrane of mitochondria. J Cell Biol (1999) 1.73
Pore-forming activity of the Tsx protein from the outer membrane of Escherichia coli. Demonstration of a nucleoside-specific binding site. J Biol Chem (1988) 1.72
Import of ADP/ATP carrier into mitochondria: two receptors act in parallel. J Cell Biol (1990) 1.72
The rate constants of valinomycin-mediated ion transport through thin lipid membranes. Biophys J (1971) 1.71
Voltage-induce capacitance relaxation of lipid bilayer membranes. Effects of membrane composition. Biochim Biophys Acta (1976) 1.71
Mitochondrial molecular chaperones: their role in protein translocation. Trends Biochem Sci (1994) 1.70
Proteinaceous receptors for the import of mitochondrial precursor proteins. J Biol Chem (1984) 1.68
Tim23 links the inner and outer mitochondrial membranes. Cell (2000) 1.68
The mitochondrial receptor complex: a central role of MOM22 in mediating preprotein transfer from receptors to the general insertion pore. Cell (1993) 1.67
Mitochondrial protein import: reversible binding of the presequence at the trans side of the outer membrane drives partial translocation and unfolding. Cell (1995) 1.66
Permeability of the cell wall of Mycobacterium smegmatis. Mol Microbiol (1994) 1.66
Biogenesis of porin of the outer mitochondrial membrane involves an import pathway via receptors and the general import pore of the TOM complex. J Cell Biol (2001) 1.65
Mitochondrial protein import: involvement of the mature part of a cleavable precursor protein in the binding to receptor sites. EMBO J (1987) 1.63
The MIM complex mediates preprotein translocation across the mitochondrial inner membrane and couples it to the mt-Hsp70/ATP driving system. Cell (1995) 1.63
A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70s. J Cell Biol (1995) 1.63