G M Ledda-Columbano

Author PubWeight™ 28.68‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Sequential analysis of multistage hepatocarcinogenesis reveals that miR-100 and PLK1 dysregulation is an early event maintained along tumor progression. Oncogene 2012 1.11
2 Occurrence of cell death (apoptosis) during the involution of liver hyperplasia. Lab Invest 1985 1.09
3 Occurrence of cell death (apoptosis) in preneoplastic and neoplastic liver cells. A sequential study. Am J Pathol 1984 1.09
4 Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells. Apoptosis 2007 1.08
5 Cyclin D1 is an early target in hepatocyte proliferation induced by thyroid hormone (T3). FASEB J 2001 1.00
6 Cell proliferation and promotion of rat liver carcinogenesis: different effect of hepatic regeneration and mitogen induced hyperplasia on the development of enzyme-altered foci. Carcinogenesis 1990 0.96
7 Inability of mitogen-induced liver hyperplasia to support the induction of enzyme-altered islands induced by liver carcinogens. Cancer Res 1987 0.96
8 Increased expression of c-fos, c-jun and LRF-1 is not required for in vivo priming of hepatocytes by the mitogen TCPOBOP. Oncogene 1997 0.95
9 An electron microscopic study of apoptosis induced by cycloheximide in rat liver. Liver 1994 0.93
10 Differences in the steady-state levels of c-fos, c-jun and c-myc messenger RNA during mitogen-induced liver growth and compensatory regeneration. Hepatology 1993 0.91
11 Triiodothyronine stimulates hepatocyte proliferation in two models of impaired liver regeneration. Cell Prolif 2008 0.89
12 Liver cell proliferation induced by nafenopin and cyproterone acetate is not associated with increases in activation of transcription factors NF-kappaB and AP-1 or with expression of tumor necrosis factor alpha. Hepatology 1997 0.88
13 Effects of cell proliferation and cell death (apoptosis and necrosis) on the early stages of rat hepatocarcinogenesis. Carcinogenesis 1996 0.88
14 Mitogenesis by ligands of nuclear receptors: an attractive model for the study of the molecular mechanisms implicated in liver growth. Cell Death Differ 2003 0.87
15 Liver hyperplasia is not necessarily associated with increased expression of c-fos and c-myc mRNA. Carcinogenesis 1990 0.87
16 Cell proliferation in rat kidney induced by 1,2-dibromoethane. Toxicol Lett 1987 0.83
17 Ploidy and nuclearity of rat hepatocytes after compensatory regeneration or mitogen-induced liver growth. Carcinogenesis 1993 0.83
18 Roles of growth factors and of tumor necrosis factor-alpha on liver cell proliferation induced in rats by lead nitrate. Lab Invest 1994 0.82
19 Induction of cellular DNA synthesis in the pancreas and kidneys of rats by peroxisome proliferators, 9-cis retinoic acid, and 3,3',5-triiodo-L-thyronine. Cancer Res 1997 0.82
20 Possible roles of nonparenchymal cells in hepatocyte proliferation induced by lead nitrate and by tumor necrosis factor alpha. Hepatology 1996 0.81
21 Different effects of regenerative and direct mitogenic stimuli on the growth of initiated cells in the resistant hepatocyte model. Jpn J Cancer Res 1993 0.81
22 Hexose monophosphate shunt and cholesterogenesis in lead-induced kidney hyperplasia. Chem Biol Interact 1987 0.80
23 Enhancement of cholesterol synthesis and pentose phosphate pathway activity in proliferating hepatocyte nodules. Carcinogenesis 1985 0.80
24 Failure of mitogen-induced cell proliferation to achieve initiation of rat liver carcinogenesis. Carcinogenesis 1987 0.80
25 Genotoxic and non-genotoxic activities of 2,4- and 2,6-diaminotoluene, as evaluated in Fischer-344 rat liver. Toxicology 1995 0.80
26 Peroxisome proliferator-activated receptor-alpha mice show enhanced hepatocyte proliferation in response to the hepatomitogen 1,4-bis [2-(3,5-dichloropyridyloxy)] benzene, a ligand of constitutive androstane receptor. Hepatology 2001 0.80
27 Genetic mapping and expression analysis of the murine DNA ligase I gene. Mol Carcinog 1995 0.80
28 Hepatocyte proliferation induced by a single dose of a peroxisome proliferator. Am J Pathol 1996 0.79
29 Lead nitrate induces certain biochemical properties characteristic of hepatocyte nodules. Carcinogenesis 1986 0.79
30 Lead and liver cell proliferation. Effect of repeated administrations. Am J Pathol 1983 0.79
31 Induction of rat liver glutathione transferase subunit 7 by lead nitrate. Cancer Lett 1989 0.78
32 Involvement of DNA polymerase beta in proliferation of rat liver induced by lead nitrate or partial hepatectomy. FEBS Lett 1992 0.77
33 Chemically induced cell proliferation and carcinogenesis: differential effect of compensatory cell proliferation and mitogen-induced direct hyperplasia on hepatocarcinogenesis in the rat. Prog Clin Biol Res 1991 0.76
34 Stimulation of DNA synthesis by rat plasma following in vivo treatment with three liver mitogens. Cancer Lett 1992 0.75
35 Liver hyperplasia and regression after lead nitrate administration. Toxicol Pathol 1984 0.75
36 HMP-shunt and cholesterol metabolism in experimental models involving normal and preneoplastic liver growth. Toxicol Pathol 1987 0.75
37 Early ultrastructural changes during thioacetamide-induced apoptosis in rat liver. J Submicrosc Cytol Pathol 1992 0.75
38 Modulation of the activity of hepatic gamma-glutamyl transpeptidase, adenosine triphosphatase, placental glutathione S-transferase and adenylate cyclase by acute administration of lead nitrate. Basic Appl Histochem 1988 0.75
39 Regulation of poly(ADP-ribose) polymerase mRNA levels during compensatory and mitogen-induced growth of rat liver. Arch Biochem Biophys 1990 0.75
40 Studies on the kinetics of expression of cell cycle dependent proto-oncogenes during mitogen-induced liver cell proliferation. Cancer Lett 1989 0.75
41 Induction of the placental form of glutathione S-transferase by lead nitrate administration in rat liver. Toxicol Pathol 1987 0.75
42 Stimulation of DNA synthesis after a single administration of cadmium nitrate. Toxicol Lett 1984 0.75