Published in Infect Immun on July 01, 1996
Interleukin-12 promotes gamma interferon-dependent neutrophil recruitment in the lung and improves protection against respiratory Streptococcus pneumoniae infection. Infect Immun (2007) 1.64
Interleukin-12 in infectious diseases. Clin Microbiol Rev (1997) 1.63
Cross-talk with myeloid accessory cells regulates human natural killer cell interferon-gamma responses to malaria. PLoS Pathog (2006) 1.40
Interleukin-12 enhances in vivo parasiticidal effect of benznidazole during acute experimental infection with a naturally drug-resistant strain of Trypanosoma cruzi. Antimicrob Agents Chemother (1998) 1.15
Trypanosoma cruzi infects human dendritic cells and prevents their maturation: inhibition of cytokines, HLA-DR, and costimulatory molecules. Infect Immun (1999) 1.12
Temporal expression of pro-inflammatory cytokines and inducible nitric oxide synthase in experimental acute Chagasic cardiomyopathy. Am J Pathol (1998) 1.12
During Trypanosoma cruzi infection CD1d-restricted NK T cells limit parasitemia and augment the antibody response to a glycophosphoinositol-modified surface protein. Infect Immun (2002) 1.09
Macrophage migration inhibitory factor contributes to host defense against acute Trypanosoma cruzi infection. Infect Immun (2006) 1.05
Coadministration of an interleukin-12 gene and a Trypanosoma cruzi gene improves vaccine efficacy. Infect Immun (2002) 0.99
Role of interleukin 12 in experimental neonatal sepsis caused by group B streptococci. Infect Immun (1997) 0.98
Glycoinositolphospholipids from Trypanosoma cruzi interfere with macrophages and dendritic cell responses. Infect Immun (2002) 0.98
CD40 ligation prevents Trypanosoma cruzi infection through interleukin-12 upregulation. Infect Immun (1999) 0.97
Effects of interleukin-4 deprivation and treatment on resistance to Trypanosoma cruzi. Infect Immun (2000) 0.97
Activation of natural killer T cells by alpha-galactosylceramide impairs DNA vaccine-induced protective immunity against Trypanosoma cruzi. Infect Immun (2003) 0.97
NK cells contribute to the control of Trypanosoma cruzi infection by killing free parasites by perforin-independent mechanisms. Infect Immun (2004) 0.94
Resistant mice lacking interleukin-12 become susceptible to Trypanosoma cruzi infection but fail to mount a T helper type 2 response. Immunology (2003) 0.91
Gene gun-mediated delivery of an interleukin-12 expression plasmid protects against infections with the intracellular protozoan parasites Leishmania major and Trypanosoma cruzi in mice. Immunology (2000) 0.90
Trypanosoma cruzi induces regulatory dendritic cells in vitro. Infect Immun (2008) 0.88
Circulating levels of cyclooxygenase metabolites in experimental Trypanosoma cruzi infections. Mediators Inflamm (2004) 0.88
Enhancement of natural killer (NK) cell cytotoxicity and induction of NK cell-derived interferon-gamma (IFN-gamma) display different kinetics during experimental infection with Trypanosoma cruzi. Clin Exp Immunol (2000) 0.86
Differential inhibitory mechanism of cyclic AMP on TNF-alpha and IL-12 synthesis by macrophages exposed to microbial stimuli. Br J Pharmacol (1999) 0.82
Preferential brain homing following intranasal administration of Trypanosoma cruzi. Infect Immun (2009) 0.81
Trypanosoma cruzi infection in genetically selected mouse lines: genetic linkage with quantitative trait locus controlling antibody response. Mediators Inflamm (2014) 0.78
Interference of natural mouse hepatitis virus infection with cytokine production and susceptibility to Trypanosoma cruzi. Immunology (1999) 0.76
Evaluation of VDR gene polymorphisms in Trypanosoma cruzi infection and chronic Chagasic cardiomyopathy. Sci Rep (2016) 0.75
CD40-CD40L interaction in immunity against protozoan infections. J Biomed Biotechnol (2007) 0.75
During acute experimental infection with the reticulotropic Trypanosoma cruzi strain Tulahuen IL-22 is induced IL-23-dependently but is dispensable for protection. Sci Rep (2016) 0.75
Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol (1995) 10.65
Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J Exp Med (1993) 8.03
Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proc Natl Acad Sci U S A (1993) 6.87
Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc Natl Acad Sci U S A (1993) 6.33
Recombinant interleukin 12 cures mice infected with Leishmania major. J Exp Med (1993) 5.75
Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response. J Exp Med (1993) 5.71
Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii. J Immunol (1994) 4.86
Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma. J Immunol (1994) 3.50
Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection. J Exp Med (1992) 3.34
Toxoplasma gondii induces a T-independent IFN-gamma response in natural killer cells that requires both adherent accessory cells and tumor necrosis factor-alpha. J Immunol (1993) 3.25
Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor beta (TGF-beta). J Exp Med (1991) 2.68
Activity of recombinant tumor necrosis factor on Toxoplasma gondii and Trypanosoma cruzi. J Immunol (1986) 2.53
Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha. Infect Immun (1994) 2.48
Interleukin-12 enhances murine survival against acute toxoplasmosis. Infect Immun (1994) 2.39
Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-gamma in vivo. Int Immunol (1994) 2.31
Interleukin-12. J Leukoc Biol (1994) 2.22
IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-gamma and TNF-alpha and occurs via a nitric oxide-dependent mechanism. J Immunol (1995) 2.12
Effects of IL-12 on immune responses to microbial infections: a key mediator in regulating disease outcome. Curr Opin Immunol (1995) 1.99
Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells. Infect Immun (1996) 1.93
Depletion of CD8+ T cells increases susceptibility and reverses vaccine-induced immunity in mice infected with Trypanosoma cruzi. J Immunol (1990) 1.92
Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids. J Exp Med (1995) 1.80
Interleukin 12 induction of interferon gamma-dependent protection against malaria. Proc Natl Acad Sci U S A (1994) 1.77
Transforming growth factor beta as a virulence mechanism for Leishmania braziliensis. Proc Natl Acad Sci U S A (1993) 1.76
IL-12 is both required and prognostic in vivo for T helper type 1 differentiation in murine candidiasis. J Immunol (1994) 1.75
Differential susceptibilities of mice genomically deleted of CD4 and CD8 to infections with Trypanosoma cruzi or Trypanosoma brucei. Infect Immun (1993) 1.59
Regulation of NK cell functions by TGF-beta 1. J Immunol (1995) 1.51
Cytokine mRNA in the central nervous system of SCID mice infected with Toxoplasma gondii: importance of T-cell-independent regulation of resistance to T. gondii. Infect Immun (1993) 1.44
Studies on the role of interleukin-12 in acute murine toxoplasmosis. Immunology (1995) 1.43
The role of the innate immune response in Th1 cell development following Leishmania major infection. J Leukoc Biol (1995) 1.40
Depletion of T-cell subpopulations results in exacerbation of myocarditis and parasitism in experimental Chagas' disease. Infect Immun (1994) 1.38
Interleukin-12 but not interferon-gamma production correlates with induction of T helper type-1 phenotype in murine candidiasis. Eur J Immunol (1994) 1.33
Effect of recombinant tumour necrosis factor on acute infection in mice with Toxoplasma gondii or Trypanosoma cruzi. Immunology (1989) 1.33
L3T4+ T cells able to mediate parasite-specific delayed-type hypersensitivity play a role in the pathology of experimental Chagas' disease. Eur J Immunol (1987) 1.20
Increased natural killer cell activity in experimental American trypanosomiasis. J Immunol (1981) 1.17
Development of resistance to Trypanosoma cruzi in mice depends on a viable population of L3T4+ (CD4+) T lymphocytes. Infect Immun (1989) 1.17
The role of T cells in Trypanosoma cruzi infections. Parasitol Today (1995) 1.03
What are T-cell subpopulations really doing in chagas disease? Parasitol Today (1995) 0.80
IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi. J Immunol (1997) 2.50
Trovafloxacin is active against Toxoplasma gondii. Antimicrob Agents Chemother (1996) 1.32
Rifabutin is active in murine models of toxoplasmosis. Antimicrob Agents Chemother (1994) 1.25
Uniject as a delivery system for the once-a-month injectable contraceptive Cyclofem in Brazil. Contraception (1996) 1.01
Activity of trovafloxacin in combination with other drugs for treatment of acute murine toxoplasmosis. Antimicrob Agents Chemother (1997) 1.01
Nonionic block copolymers potentiate activities of drugs for treatment of infections with Toxoplasma gondii. Antimicrob Agents Chemother (1995) 0.89
Chronic infection with Toxoplasma gondii does not prevent acute disease or colonization of the brain with tissue cysts following reinfection with different strains of the parasite. J Parasitol (1997) 0.87
Role of beta interferon in resistance to Toxoplasma gondii infection. Infect Immun (1991) 0.87
Dopamine D2 receptor polymorphisms in inflammatory bowel disease and the refractory response to treatment. Dig Dis Sci (2006) 0.85
GABAA receptor subunit expression changes in the rat cerebellum and cerebral cortex during aging. Brain Res Mol Brain Res (1997) 0.84
Soluble selectins, sICAM, sVCAM, and angiogenic proteins in different activity groups of patients with inflammatory bowel disease. Dig Dis Sci (2004) 0.83
Gemifloxacin inhibits cytokine secretion by lipopolysaccharide stimulated human monocytes at the post-transcriptional level. Clin Microbiol Infect (2004) 0.81
GABAA and alpha-amino-3-hydroxy-5-methylsoxazole-4-propionate receptors are differentially affected by aging in the rat hippocampus. J Biol Chem (2000) 0.81
Some phosphonic acid analogs as inhibitors of pyrophosphate-dependent phosphofructokinase, a novel target in Toxoplasma gondii. Biochem Pharmacol (1995) 0.79
[Lymphangioma of the palatine tonsil (author's transl)]. Ann Otolaryngol Chir Cervicofac (1977) 0.79
Photolyase/cryptochrome family blue-light photoreceptors use light energy to repair DNA or set the circadian clock. Cold Spring Harb Symp Quant Biol (2000) 0.78
Prevalence between different alpha subunits performing the benzodiazepine binding sites in native heterologous GABA(A) receptors containing the alpha2 subunit. J Neurochem (2001) 0.77
Treadmill exercise testing of asymptomatic men and women without evidence of heart disease. Braz J Med Biol Res (2009) 0.76
Pharmacological properties of the GABA(A) receptor complex from brain regions of (hypoemotional) Roman high- and (hyperemotional) low-avoidance rats. Eur J Pharmacol (1998) 0.76
Molecular characterization of type I GABAA receptor complex from rat cerebral cortex and hippocampus. Brain Res Mol Brain Res (1994) 0.76
[Pralidoxime for organophosphate poisoning: regarding two paediatric cases]. Farm Hosp (2009) 0.75
Age-related modifications on the GABAA receptor binding properties from Wistar rat prefrontal cortex. Brain Res (1996) 0.75
[Ezetimibe: caution in the face of doubt]. Farm Hosp (2010) 0.75
[Osteomyelitis associated with Staphylococcus aureus infection and reduced susceptibility to vancomycin treated with daptomycin]. Farm Hosp (2012) 0.75
[Septic shock. Update of treatment using hypertonic saline and antidiuretic hormone-vasopressin]. Rev Esp Anestesiol Reanim (2012) 0.75
Distribution of the gamma-aminobutyric acid(A) receptor complex alpha 5 subunit in chick brain. An immunocytochemical and autoradiographic study. Neurosci Lett (2000) 0.75
[Giant evoked potentials]. Rev Neurol (2002) 0.75