Published in Nature on August 08, 1996
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myc boxes, which are conserved in myc family proteins, are signals for protein degradation via the proteasome. Mol Cell Biol (1998) 1.77
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Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function. Mol Cell Biol (2001) 1.57
An in vivo function for the transforming Myc protein: elicitation of the angiogenic phenotype. Cell Growth Differ (2000) 1.54
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The role of histone demethylase KDM4B in Myc signaling in neuroblastoma. J Natl Cancer Inst (2015) 1.46
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c-Myc overexpression uncouples DNA replication from mitosis. Mol Cell Biol (1999) 1.42
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Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype. Proc Natl Acad Sci U S A (1997) 1.37
Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues. Mol Cell Biol (2004) 1.35
Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway. Mol Cell Biol (2000) 1.34
The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survival. Genes Dev (1999) 1.32
Activation of the myc oncoprotein leads to increased turnover of thrombospondin-1 mRNA. Nucleic Acids Res (2000) 1.28
Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway. Proc Natl Acad Sci U S A (2002) 1.26
The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice. EMBO J (2000) 1.24
High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene, CDC25A. Cancer Cell (2011) 1.22
Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276. Leukemia (2013) 1.21
c-Myc/Max heterodimers bind cooperatively to the E-box sequences located in the first intron of the rat ornithine decarboxylase (ODC) gene. Nucleic Acids Res (1997) 1.20
Mechanisms of cyclin-dependent kinase inactivation by progestins. Mol Cell Biol (1998) 1.20
Overexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expression. Mol Cell Biol (2000) 1.19
Serum-induced expression of the cdc25A gene by relief of E2F-mediated repression. Mol Cell Biol (1999) 1.19
The winged-helix/forkhead protein myocyte nuclear factor beta (MNF-beta) forms a co-repressor complex with mammalian sin3B. Biochem J (2000) 1.18
Estrogen regulation of cyclin E2 requires cyclin D1 but not c-Myc. Mol Cell Biol (2009) 1.16
Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction. Oncogene (2010) 1.16
Transforming growth factor beta1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc. J Exp Med (1999) 1.14
Myc represses transcription of the growth arrest gene gas1. Proc Natl Acad Sci U S A (1997) 1.13
Activated Src abrogates the Myc requirement for the G0/G1 transition but not for the G1/S transition. Proc Natl Acad Sci U S A (2006) 1.11
Myc is an essential negative regulator of platelet-derived growth factor beta receptor expression. Mol Cell Biol (2000) 1.08
Transforming growth factor-beta and breast cancer: Cell cycle arrest by transforming growth factor-beta and its disruption in cancer. Breast Cancer Res (2000) 1.07
The synergistic cytotoxicity of clofarabine, fludarabine and busulfan in AML cells involves ATM pathway activation and chromatin remodeling. Biochem Pharmacol (2010) 1.07
ECA39 is a novel distant metastasis-related biomarker in colorectal cancer. World J Gastroenterol (2006) 1.07
The cell cycle-regulatory CDC25A phosphatase inhibits apoptosis signal-regulating kinase 1. Mol Cell Biol (2001) 1.06
Coding elements in exons 2 and 3 target c-myc mRNA downregulation during myogenic differentiation. Mol Cell Biol (1997) 1.04
Clinical significance of CDC25A and CDC25B expression in squamous cell carcinomas of the oesophagus. Br J Cancer (2001) 1.04
MMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancer. Expert Rev Mol Diagn (2009) 1.02
Functional interactions among members of the MAX and MLX transcriptional network during oncogenesis. Biochim Biophys Acta (2014) 1.02
Targeting cyclin-dependent kinase 1 (CDK1) but not CDK4/6 or CDK2 is selectively lethal to MYC-dependent human breast cancer cells. BMC Cancer (2014) 1.01
Caspase-dependent Cdk activity is a requisite effector of apoptotic death events. J Cell Biol (2000) 1.01
A bioinformatics-based strategy identifies c-Myc and Cdc25A as candidates for the Apmt mammary tumor latency modifiers. Genome Res (2002) 1.01
The role of Cdc25A in the regulation of cell proliferation and apoptosis. Anticancer Agents Med Chem (2012) 0.99
The cell cycle Cdc25A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease. Am J Pathol (2000) 0.99
WNT signaling: an emerging mediator of cancer cell metabolism? Mol Cell Biol (2014) 0.99
FIN13, a novel growth factor-inducible serine-threonine phosphatase which can inhibit cell cycle progression. Mol Cell Biol (1997) 0.98
The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models. Oncogene (2015) 0.97
Chromosomal and extrachromosomal instability of the cyclin D2 gene is induced by Myc overexpression. Neoplasia (1999) 0.97
E2F-Rb complexes assemble and inhibit cdc25A transcription in cervical carcinoma cells following repression of human papillomavirus oncogene expression. Mol Cell Biol (2000) 0.96
MYC and the art of microRNA maintenance. Cold Spring Harb Perspect Med (2014) 0.94
Cdc25B functions as a novel coactivator for the steroid receptors. Mol Cell Biol (2001) 0.90
The tumor suppressor protein HBP1 is a novel c-myc-binding protein that negatively regulates c-myc transcriptional activity. J Biol Chem (2009) 0.88
Constitutive expression of ectopic c-Myc delays glucocorticoid-evoked apoptosis of human leukemic CEM-C7 cells. Oncogene (2001) 0.87
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