On immunological memory.

PubWeight™: 3.21‹?› | Rank: Top 1%

🔗 View Article (PMID 8717518)

Published in Annu Rev Immunol on January 01, 1996

Authors

R M Zinkernagel1, M F Bachmann, T M Kündig, S Oehen, H Pirchet, H Hengartner

Author Affiliations

1: Department of Pathology, University of Zürich, Switzerland.

Articles citing this

Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. Immunity (2007) 6.48

Rapid effector function in CD8+ memory T cells. J Exp Med (1997) 6.36

Antigen localization and migration in immunity and tolerance. N Engl J Med (1998) 3.71

Organization of immunological memory by bone marrow stroma. Nat Rev Immunol (2010) 3.57

An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proc Natl Acad Sci U S A (1999) 3.15

TLR2 is expressed on activated T cells as a costimulatory receptor. Proc Natl Acad Sci U S A (2004) 3.04

Hierarchical and redundant lymphocyte subset control precludes cytomegalovirus replication during latent infection. J Exp Med (1998) 2.60

On the role of antigen in maintaining cytotoxic T-cell memory. Proc Natl Acad Sci U S A (1996) 2.55

T cell stimulation in vivo by lipopolysaccharide (LPS). J Exp Med (1997) 2.29

Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"? Proc Natl Acad Sci U S A (1997) 2.23

A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers. Proc Natl Acad Sci U S A (1997) 2.20

Conserved T cell receptor repertoire in primary and memory CD8 T cell responses to an acute viral infection. J Exp Med (1998) 2.13

Superior T memory stem cell persistence supports long-lived T cell memory. J Clin Invest (2013) 2.06

The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections. PLoS Pathog (2010) 2.03

Functional differences between memory and naive CD8 T cells. Proc Natl Acad Sci U S A (1999) 1.94

New insights into the differentiation and function of T follicular helper cells. Nat Rev Immunol (2009) 1.92

Display technologies: application for the discovery of drug and gene delivery agents. Adv Drug Deliv Rev (2006) 1.92

Attrition of bystander CD8 T cells during virus-induced T-cell and interferon responses. J Virol (2001) 1.87

Migration and function of antigen-primed nonpolarized T lymphocytes in vivo. J Exp Med (2001) 1.83

Long-lived autoreactive plasma cells drive persistent autoimmune inflammation. Nat Rev Rheumatol (2011) 1.82

Maintenance of the plasma cell pool is independent of memory B cells. Proc Natl Acad Sci U S A (2008) 1.75

Virus-specific CD8(+) T cell numbers are maintained during gamma-herpesvirus reactivation in CD4-deficient mice. Proc Natl Acad Sci U S A (1998) 1.73

Rapid default transition of CD4 T cell effectors to functional memory cells. J Exp Med (2007) 1.69

Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model. Proc Natl Acad Sci U S A (1998) 1.59

Protective long-term antibody memory by antigen-driven and T help-dependent differentiation of long-lived memory B cells to short-lived plasma cells independent of secondary lymphoid organs. Proc Natl Acad Sci U S A (2000) 1.57

Expansion of protective CD8+ T-cell responses driven by recombinant cytomegaloviruses. J Virol (2004) 1.55

Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A. J Virol (2008) 1.52

Retracted Prophylactic DNA vaccine for hepatitis C virus (HCV) infection: HCV-specific cytotoxic T lymphocyte induction and protection from HCV-recombinant vaccinia infection in an HLA-A2.1 transgenic mouse model. Proc Natl Acad Sci U S A (2000) 1.51

Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo. J Exp Med (2000) 1.50

A comparison of T cell memory against the same antigen induced by virus versus intracellular bacteria. Proc Natl Acad Sci U S A (1999) 1.49

Qualitative differences between naïve and memory T cells. Immunology (2002) 1.48

Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells. J Exp Med (1999) 1.42

Influenza virus-like particles containing M2 induce broadly cross protective immunity. PLoS One (2011) 1.40

Robust recall and long-term memory T-cell responses induced by prime-boost regimens with heterologous live viral vectors expressing human immunodeficiency virus type 1 Gag and Env proteins. J Virol (2002) 1.36

Persistence of lymphocytic choriomeningitis virus at very low levels in immune mice. Proc Natl Acad Sci U S A (1999) 1.35

Postexposure vaccination massively increases the prevalence of gamma-herpesvirus-specific CD8+ T cells but confers minimal survival advantage on CD4-deficient mice. Proc Natl Acad Sci U S A (2000) 1.34

B lymphocyte memory: role of stromal cell complement and FcgammaRIIB receptors. J Exp Med (2002) 1.32

Memory CD8+ T cells are gatekeepers of the lymph node draining the site of viral infection. Proc Natl Acad Sci U S A (2007) 1.31

Functional management of an antiviral cytotoxic T-cell response. J Virol (1997) 1.30

Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles. Virology (2007) 1.29

A new theory of cytotoxic T-lymphocyte memory: implications for HIV treatment. Philos Trans R Soc Lond B Biol Sci (2000) 1.20

Specific therapy regimes could lead to long-term immunological control of HIV. Proc Natl Acad Sci U S A (1999) 1.18

Exploring pathways for memory T cell generation. J Clin Invest (2001) 1.18

Specifically activated memory T cell subsets from cancer patients recognize and reject xenotransplanted autologous tumors. J Clin Invest (2004) 1.16

Functional memory B cells and long-lived plasma cells are generated after a single Plasmodium chabaudi infection in mice. PLoS Pathog (2009) 1.15

Live nonpathogenic parasitic vector as a candidate vaccine against visceral leishmaniasis. Infect Immun (2005) 1.11

Chimerism and tolerance in transplantation. Proc Natl Acad Sci U S A (2004) 1.07

Short-term immunoglobulin A B-cell memory resides in intestinal lymphoid tissues but not in bone marrow of gnotobiotic pigs inoculated with Wa human rotavirus. Immunology (2001) 1.06

Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1. J Exp Med (2005) 1.04

Treatment with soluble interleukin-15Ralpha exacerbates intracellular parasitic infection by blocking the development of memory CD8+ T cell response. J Exp Med (2002) 1.02

Salmonella porins induce a sustained, lifelong specific bactericidal antibody memory response. Immunology (2006) 1.01

Proliferation capacity and cytotoxic activity are mediated by functionally and phenotypically distinct virus-specific CD8 T cells defined by interleukin-7R{alpha} (CD127) and perforin expression. J Virol (2010) 0.98

Profile of central and effector memory T cells in the progression of chronic human chagas disease. PLoS Negl Trop Dis (2009) 0.96

Rapid T cell-based identification of human tumor tissue antigens by automated two-dimensional protein fractionation. J Clin Invest (2010) 0.95

Influenza infection results in local expansion of memory CD8(+) T cells with antigen non-specific phenotype and function. Clin Exp Immunol (2014) 0.94

Memory CD8 T cells specific for plasmodia liver-stage antigens maintain protracted protection against malaria. Front Immunol (2012) 0.94

Gene expression patterns induced by HPV-16 L1 virus-like particles in leukocytes from vaccine recipients. J Immunol (2009) 0.93

Toward improved immunocompetence of adoptively transferred CD8+ T cells. J Clin Invest (2005) 0.93

Cytokine and chemokine profiles following vaccination with human papillomavirus type 16 L1 Virus-like particles. Clin Vaccine Immunol (2007) 0.92

Translating innate response into long-lasting antibody response by the intrinsic antigen-adjuvant properties of papaya mosaic virus. Immunology (2007) 0.90

Plasma cells as an innovative target in autoimmune disease with renal manifestations. Nat Rev Nephrol (2016) 0.90

Viral escape mechanisms--escapology taught by viruses. Int J Exp Pathol (2001) 0.89

Human CD8 T cells of the peripheral blood contain a low CD8 expressing cytotoxic/effector subpopulation. Immunology (2003) 0.89

Bone marrow augmentation in renal transplant recipients. Transplant Proc (1998) 0.86

Naive T-cell receptor transgenic T cells help memory B cells produce antibody. Immunology (2006) 0.85

Limited humoral immunoglobulin E memory influences serum immunoglobulin E levels in blood. Clin Exp Allergy (2009) 0.84

T helper 1-type cytokine transcription in peripheral blood mononuclear cells of pseudorabies virus (Suid herpesvirus 1)-primed swine indicates efficient immunization. Immunology (2000) 0.84

Joining chain-expressing and -nonexpressing B cell populations in the mouse. J Exp Med (2001) 0.84

Perpetuation of immunological memory: a relay hypothesis. Immunology (2001) 0.83

Antiviral protection after DNA vaccination is short lived and not enhanced by CpG DNA. Immunology (2000) 0.83

B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites. Infect Immun (2014) 0.82

Myosin VI regulates gene pairing and transcriptional pause release in T cells. Proc Natl Acad Sci U S A (2015) 0.82

Immunity and clinical efficacy of an inactivated enterovirus 71 vaccine in healthy Chinese children: a report of further observations. BMC Med (2015) 0.80

Theoretical analysis of the evolution of immune memory. BMC Evol Biol (2010) 0.79

Early activation of CD4+ and CD8+ T lymphocytes by myelin basic protein in subjects with MS. J Transl Med (2015) 0.78

Hepatic and intestinal transplantation at the University of Pittsburgh. Clin Transpl (1998) 0.78

B cells establish, but do not maintain, long-lived murine anti-peanut IgE(a). Clin Exp Allergy (2016) 0.78

A New Twist to a Chronic HCV Infection: Occult Hepatitis C. Gastroenterol Res Pract (2015) 0.77

Cytotoxic T-lymphocyte memory, virus clearance and antigenic heterogeneity. Proc Biol Sci (2001) 0.77

Immunity and tolerance are related, and governed by antigen migration and localization. Transplant Proc (1999) 0.77

Analysis of HLA class Ia transcripts in human leukaemias. Immunogenetics (2005) 0.76

Chronic infection and the origin of adaptive immune system. Med Hypotheses (2010) 0.76

Chimerism and xenotransplantation. New concepts. Surg Clin North Am (1999) 0.75

Mathematical model reveals how regulating the three phases of T-cell response could counteract immune evasion. Immunology (2015) 0.75

[Allograft "acceptance" and tolerance: a new concept]. Bull Acad Natl Med (1998) 0.75

Cellular Immune Responses and Immune Escape Mechanisms in Breast Cancer: Determinants of Immunotherapy. Breast Care (Basel) (2016) 0.75

Adaptive immune response to viral infections in the central nervous system. Handb Clin Neurol (2014) 0.75

Impact of Donor Activating KIR Genes on HSCT Outcome in C1-Ligand Negative Myeloid Disease Patients Transplanted with Unrelated Donors-A Retrospective Study. PLoS One (2017) 0.75

Identification of human plasma cells with a lamprey monoclonal antibody. JCI Insight (2016) 0.75

Regulation of immune reactivity and tolerance by antigen migration and localization: with particular reference to allo- and xenotransplantation. Transplant Proc (1999) 0.75

Articles by these authors

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature (1994) 11.22

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell (1993) 9.84

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature (1989) 7.52

Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. Science (1994) 7.34

Differential T cell costimulatory requirements in CD28-deficient mice. Science (1993) 6.93

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell (1991) 6.49

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4. Nature (1991) 5.98

A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science (2000) 5.78

Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes. J Exp Med (1998) 5.78

Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo. Nature (1990) 5.41

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta. Science (1995) 5.27

Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell (1996) 4.74

Control of early viral and bacterial distribution and disease by natural antibodies. Science (1999) 4.73

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Cell (1993) 4.46

Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice. J Virol (1994) 4.34

Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function. Science (1997) 4.23

CD8 is needed for development of cytotoxic T cells but not helper T cells. Cell (1991) 4.05

T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens. Nature (1988) 4.04

Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction. Nature (2001) 3.99

Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates. J Virol Methods (1991) 3.78

Virus-specific MHC-class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection. Eur J Immunol (1998) 3.52

The influence of antigen organization on B cell responsiveness. Science (1993) 3.32

Immune responses in interleukin-2-deficient mice. Science (1993) 3.29

On immunity against infections and vaccines: credo 2004. Scand J Immunol (2004) 3.29

Fine specificity of a continuously growing killer cell clone specific for H-Y antigen. Eur J Immunol (1979) 3.27

IgA production without mu or delta chain expression in developing B cells. Nat Immunol (2001) 3.26

Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice. Cell (1993) 3.07

Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides. J Exp Med (1998) 3.03

Decreased tumor surveillance in perforin-deficient mice. J Exp Med (1996) 3.00

Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu Rev Immunol (1996) 2.96

Major histocompatibility complex--dependent T cell epitopes of lymphocytic choriomeningitis virus nucleoprotein and their protective capacity against viral disease. Eur J Immunol (1989) 2.71

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function. Nature (1991) 2.66

Antigen localisation regulates immune responses in a dose- and time-dependent fashion: a geographical view of immune reactivity. Immunol Rev (1997) 2.58

Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide. J Exp Med (1990) 2.58

A non-retroviral RNA virus persists in DNA form. Nature (1997) 2.57

On the role of antigen in maintaining cytotoxic T-cell memory. Proc Natl Acad Sci U S A (1996) 2.55

Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: implications for immunotherapy. J Exp Med (1997) 2.47

The roles of perforin- and Fas-dependent cytotoxicity in protection against cytopathic and noncytopathic viruses. Eur J Immunol (1995) 2.47

Structure and function of human perforin. Nature (1988) 2.47

The role of antibody concentration and avidity in antiviral protection. Science (1997) 2.45

Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure. Proc Natl Acad Sci U S A (1991) 2.41

Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse. Proc Natl Acad Sci U S A (1978) 2.38

Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity. Cell (1986) 2.38

Intrathymic deletion of self-reactive cells prevented by neonatal anti-CD4 antibody treatment. Nature (1988) 2.28

Specific cytotoxic T cells eliminate B cells producing virus-neutralizing antibodies [corrected]. Nature (1996) 2.25

T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides. Eur J Immunol (1993) 2.25

Interleukin 1 activity in the synovial fluid of patients with rheumatoid arthritis. Rheumatol Int (1982) 2.24

Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression. J Exp Med (1991) 2.24

T cell-mediated hepatitis in mice infected with lymphocytic choriomeningitis virus. Liver cell destruction by H-2 class I-restricted virus-specific cytotoxic T cells as a physiological correlate of the 51Cr-release assay? J Exp Med (1986) 2.24

Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"? Proc Natl Acad Sci U S A (1997) 2.23

Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen. J Exp Med (1992) 2.22

Clones of alloreactive T cells. Nature (1978) 2.21

Selection of the T cell repertoire. Annu Rev Immunol (1999) 2.21

T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes. J Exp Med (1986) 2.20

A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers. Proc Natl Acad Sci U S A (1997) 2.20

Immune surveillance against a solid tumor fails because of immunological ignorance. Proc Natl Acad Sci U S A (1999) 2.19

LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor. J Exp Med (1996) 2.14

FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory. J Immunol (2000) 2.13

Bystander activation of cytotoxic T cells: studies on the mechanism and evaluation of in vivo significance in a transgenic mouse model. J Exp Med (1997) 2.13

Different roles for cytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses. Curr Opin Immunol (1996) 2.11

Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells. J Immunol (1993) 2.10

Duration of TCR stimulation determines costimulatory requirement of T cells. Immunity (1996) 2.08

A central role of perforin in cytolysis? Annu Rev Immunol (1991) 2.08

T cell priming versus T cell tolerance induced by synthetic peptides. J Exp Med (1995) 2.07

Induction or prevention of immunopathological disease by cloned cytotoxic T cell lines specific for lymphocytic choriomeningitis virus. Eur J Immunol (1986) 2.06

Anti-viral protection and prevention of lymphocytic choriomeningitis or of the local footpad swelling reaction in mice by immunization with vaccinia-recombinant virus expressing LCMV-WE nucleoprotein or glycoprotein. Eur J Immunol (1989) 2.05

Fibroblasts as efficient antigen-presenting cells in lymphoid organs. Science (1995) 2.01

CD8+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity. Eur J Immunol (1994) 2.00

Susceptibility to lymphocytic choriomeningitis virus isolates correlates directly with early and high cytotoxic T cell activity, as well as with footpad swelling reaction, and all three are regulated by H-2D. J Exp Med (1985) 1.98

Vaccination for disease. Science (1991) 1.97

T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice. EMBO J (1989) 1.94

Virus-induced transient bone marrow aplasia: major role of interferon-alpha/beta during acute infection with the noncytopathic lymphocytic choriomeningitis virus. J Exp Med (1997) 1.93

OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL Responses after virus infection. Immunity (1999) 1.93

Peptide-induced antiviral protection by cytotoxic T cells. Proc Natl Acad Sci U S A (1991) 1.89

Positive selection of CD4+ thymocytes controlled by MHC class II gene products. Nature (1988) 1.86

Regulation of the immune response by antigen. Science (2001) 1.84

Comparison of activation versus induction of unresponsiveness of virus-specific CD4+ and CD8+ T cells upon acute versus persistent viral infection. Immunity (1998) 1.83

T-cell-mediated immunopathology versus direct cytolysis by virus: implications for HIV and AIDS. Immunol Today (1994) 1.81

Induction of long-lived germinal centers associated with persisting antigen after viral infection. J Exp Med (1996) 1.80

Early high-affinity neutralizing anti-viral IgG responses without further overall improvements of affinity. Proc Natl Acad Sci U S A (1995) 1.79

Protective T cell-independent antiviral antibody responses are dependent on complement. J Exp Med (1999) 1.79

CD4+ T-cell-epitope escape mutant virus selected in vivo. Nat Med (2001) 1.78

Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity. J Exp Med (1989) 1.78

Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis. J Exp Med (1997) 1.77

Two monoclonal rat antibodies with specificity for the beta-chain variable region V beta 6 of the murine T-cell receptor. Proc Natl Acad Sci U S A (1988) 1.75

Identical V beta T-cell receptor genes used in alloreactive cytotoxic and antigen plus I-A specific helper T cells. Nature (1985) 1.74

Preferential usage of V alpha 4 and V beta 10 T cell receptor genes by lymphocytic choriomeningitis virus glycoprotein-specific H-2Db-restricted cytotoxic T cells. Eur J Immunol (1990) 1.74