O Dideberg

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family. Biochem J 1988 7.51
2 Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins. Antimicrob Agents Chemother 1991 5.05
3 Standard numbering scheme for class B beta-lactamases. Antimicrob Agents Chemother 2001 4.36
4 The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold. EMBO J 1995 4.30
5 X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme. Nat Struct Biol 1996 3.09
6 On the origin of bacterial resistance to penicillin: comparison of a beta-lactamase and a penicillin target. Science 1986 2.88
7 Beta-lactamase of Bacillus licheniformis 749/C at 2 A resolution. Proteins 1990 2.49
8 Mechanism of acyl transfer by the class A serine beta-lactamase of Streptomyces albus G. Biochem J 1991 2.39
9 The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form. J Mol Biol 2007 1.94
10 The crystal structure of the penicillin-binding protein 2x from Streptococcus pneumoniae and its acyl-enzyme form: implication in drug resistance. J Mol Biol 2000 1.90
11 Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions. Mol Cell 2000 1.77
12 Crystal structure of Proteus mirabilis PR catalase with and without bound NADPH. J Mol Biol 1995 1.70
13 Structure of a Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase at 2.5 A resolution. Nature 1982 1.60
14 1.85 A resolution structure of the zinc (II) beta-lactamase from Bacillus cereus. Acta Crystallogr D Biol Crystallogr 1998 1.58
15 Crystallographic data for the beta-lactamase from Enterobacter cloacae P99. J Mol Biol 1983 1.47
16 The kappa-carrageenase of P. carrageenovora features a tunnel-shaped active site: a novel insight in the evolution of Clan-B glycoside hydrolases. Structure 2001 1.36
17 Mutations in the active site of penicillin-binding protein PBP2x from Streptococcus pneumoniae. Role in the specificity for beta-lactam antibiotics. J Biol Chem 1999 1.34
18 Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril. J Mol Biol 2003 1.33
19 Crystal structure of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-diaminopimelate ligase from Escherichia coli. J Biol Chem 2000 1.31
20 Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations. J Biol Chem 2001 1.29
21 Identification of a structural determinant for resistance to beta-lactam antibiotics in Gram-positive bacteria. Proc Natl Acad Sci U S A 1998 1.27
22 Crystal structure of the human protein kinase CK2 regulatory subunit reveals its zinc finger-mediated dimerization. EMBO J 1999 1.25
23 Engineering a novel beta-lactamase by a single point mutation. Protein Eng 1990 1.23
24 Crystal structure of UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase from Escherichia coli. EMBO J 1997 1.20
25 X-ray structure of the ZnII beta-lactamase from Bacteroides fragilis in an orthorhombic crystal form. Acta Crystallogr D Biol Crystallogr 1998 1.17
26 Crystal structure study of Opsanus tau parvalbumin by multiwavelength anomalous diffraction. FEBS Lett 1985 1.16
27 Identification, purification, and characterization of transpeptidase and glycosyltransferase domains of Streptococcus pneumoniae penicillin-binding protein 1a. J Bacteriol 1998 1.14
28 Amino acid sequence of the penicillin-binding protein/DD-peptidase of Streptomyces K15. Predicted secondary structures of the low Mr penicillin-binding proteins of class A. Biochem J 1991 1.13
29 Arginine 220 is a critical residue for the catalytic mechanism of the Streptomyces albus G beta-lactamase. Protein Eng 1991 1.12
30 Properties and crystallization of a genetically engineered, water-soluble derivative of penicillin-binding protein 5 of Escherichia coli K12. Eur J Biochem 1988 1.11
31 Site-directed mutagenesis of proposed active-site residues of penicillin-binding protein 5 from Escherichia coli. Biochem J 1994 1.11
32 Crystal structure of Pseudomonas aeruginosa catabolic ornithine transcarbamoylase at 3.0-A resolution: a different oligomeric organization in the transcarbamoylase family. Proc Natl Acad Sci U S A 1995 1.11
33 Primary and predicted secondary structures of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4. Biochem J 1992 1.11
34 Determination of the MurD mechanism through crystallographic analysis of enzyme complexes. J Mol Biol 1999 1.10
35 Crystallization and preliminary X-ray data for the exocellular beta-lactamase of Bacillus licheniformis 749/C. J Mol Biol 1985 1.09
36 The structures and catalytic mechanisms of active-site serine beta-lactamases. Biotechnol Genet Eng Rev 1994 1.09
37 Glycosyltransferase domain of penicillin-binding protein 2a from Streptococcus pneumoniae is membrane associated. J Bacteriol 1999 1.05
38 Crystallization of a genetically engineered water-soluble primary penicillin target enzyme. The high molecular mass PBP2x of Streptococcus pneumoniae. J Mol Biol 1993 1.05
39 Comparison of the structures of wild-type and a N313T mutant of Escherichia coli glyceraldehyde 3-phosphate dehydrogenases: implication for NAD binding and cooperativity. J Mol Biol 1996 1.02
40 "Open" structures of MurD: domain movements and structural similarities with folylpolyglutamate synthetase. J Mol Biol 2000 1.02
41 Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J Mol Biol 2007 1.01
42 Bacterial wall peptidoglycan, DD-peptidases and beta-lactam antibiotics. Scand J Infect Dis Suppl 1984 0.99
43 The exocellular DD-carboxypeptidase of Streptomyces albus G: a metallo (Zn2+) enzyme. FEBS Lett 1980 0.97
44 Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila. Antimicrob Agents Chemother 2007 0.96
45 Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments. Eur J Biochem 2001 0.94
46 Catabolic ornithine carbamoyltransferase of Pseudomonas aeruginosa. Importance of the N-terminal region for dodecameric structure and homotropic carbamoylphosphate cooperativity. Eur J Biochem 1996 0.92
47 Role of the ortholog and paralog amino acid invariants in the active site of the UDP-MurNAc-L-alanine:D-glutamate ligase (MurD). Biochemistry 1999 0.92
48 The iota-carrageenase of Alteromonas fortis. A beta-helix fold-containing enzyme for the degradation of a highly polyanionic polysaccharide. J Biol Chem 2001 0.90
49 The 4.5 A resolution structure analysis of the exocellular DD-carboxypeptidase of Streptomyces albus G. FEBS Lett 1980 0.89
50 Biochemical characterisation of ornithine carbamoyltransferase from Pyrococcus furiosus. Eur J Biochem 1997 0.89
51 Molecular size and symmetry of Pseudomonas aeruginosa catabolic ornithine carbamoyltransferase. An X-ray crystallography analysis. J Mol Biol 1991 0.86
52 Allosteric regulation in Pseudomonas aeruginosa catabolic ornithine carbamoyltransferase revisited: association of concerted homotropic cooperative interactions and local heterotropic effects. J Mol Biol 1998 0.85
53 Preference of Cd(II) and Zn(II) for the two metal sites in Bacillus cereus beta-lactamase II: A perturbed angular correlation of gamma-rays spectroscopic study. Biochemistry 1999 0.84
54 A crystallographic comparison between mutated glyceraldehyde-3-phosphate dehydrogenases from Bacillus stearothermophilus complexed with either NAD+ or NADP+. J Mol Biol 1997 0.84
55 Processing and hydrolytic mechanism of the cgkA-encoded kappa-carrageenase of Alteromonas carrageenovora. Eur J Biochem 1995 0.83
56 Catabolic ornithine carbamoyltransferase of Pseudomonas aeruginosa. Changes of allosteric properties resulting from modifications at the C-terminus. Eur J Biochem 1994 0.83
57 Kinetic studies of allosteric catabolic ornithine carbamoyltransferase from Pseudomonas aeruginosa. Eur J Biochem 1998 0.82
58 Methionine-321 in the C-terminal alpha-helix of catabolic ornithine carbamoyltransferase from Pseudomonas aeruginosa is important for positive homotropic cooperativity. FEMS Microbiol Lett 1994 0.81
59 Crystallization and preliminary x-ray diffraction analysis of the regulatory subunit of human protein kinase CK2. Acta Crystallogr D Biol Crystallogr 1999 0.80
60 Deacylation kinetics analysis of Streptococcus pneumoniae penicillin-binding protein 2x mutants resistant to beta-lactam antibiotics using electrospray ionization- mass spectrometry. Anal Biochem 2000 0.80
61 Structural effects of the active site mutation cysteine to serine in Bacillus cereus zinc-beta-lactamase. Protein Sci 2000 0.80
62 Large-scale preparation, purification, and crystallization of UDP-N-acetylmuramoyl-L-alanine: D-glutamate ligase from Escherichia coli. Protein Expr Purif 1998 0.79
63 Purification, crystallization and preliminary X-ray analysis of Bacteroides fragilis Zn2+ beta-lactamase. Acta Crystallogr D Biol Crystallogr 1997 0.79
64 Crystallographic data for the DD-carboxypeptidase-endopeptidase of low penicillin sensitivity excreted by Streptomyces albus g. J Mol Biol 1979 0.79
65 Molecular mechanisms of antibiotic resistance in gram-positive pathogens. Curr Drug Targets Infect Disord 2001 0.78
66 Study of the Zn-containing DD-carboxypeptidase of Streptomyces albus G by small-angle X-ray scattering in solution. Eur J Biochem 1984 0.78
67 Use of a designed fusion protein dissociates allosteric properties from the dodecameric state of Pseudomonas aeruginosa catabolic ornithine carbamoyltransferase. Proc Natl Acad Sci U S A 1996 0.78
68 Expression, purification, crystallization and preliminary x-ray analysis of the kappa-carrageenase from Pseudoalteromonas carrageenovora. Acta Crystallogr D Biol Crystallogr 1999 0.76
69 Expression, purification, crystallization and preliminary X-ray analysis of the iota-carrageenase from Alteromonas fortis. Acta Crystallogr D Biol Crystallogr 2000 0.76
70 Penicillin-recognizing enzymes. Biochem Soc Trans 1988 0.76
71 Active-site-directed inactivators of the Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase of Streptomyces albus G. Biochem J 1984 0.75
72 Crystallization and preliminary X-ray data for parvalbumin IIIf of Opsanus tau. J Mol Biol 1981 0.75
73 Crystallographic studies of low penicillin-sensitive enzyme excreted by Streptomyces albus G [proceedings]. Arch Int Physiol Biochim 1979 0.75
74 Purification, crystallization and preliminary X-ray analysis of catabolic ornithine carbamoyltransferase from Pseudomonas aeruginosa. Acta Crystallogr D Biol Crystallogr 1999 0.75
75 Possible hydrogen-bond interactions of steroid hormones--II. Corticosteroids. J Steroid Biochem 1976 0.75
76 Primary and predicted secondary structure of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4. Biochem J 1992 0.75
77 Crystallization and preliminary X-ray diffraction studies of Escherichia coli glyceraldehyde-3-phosphate dehydrogenase. Acta Crystallogr D Biol Crystallogr 1995 0.75
78 Crystal and molecular structure of BN 52021, a PAF-acether antagonist. Comparison with the conformation of Kadsurenone and related compounds. Pharmacol Res Commun 1986 0.75