| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family.
|
Biochem J
|
1988
|
7.51
|
|
2
|
Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins.
|
Antimicrob Agents Chemother
|
1991
|
5.05
|
|
3
|
Standard numbering scheme for class B beta-lactamases.
|
Antimicrob Agents Chemother
|
2001
|
4.36
|
|
4
|
The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold.
|
EMBO J
|
1995
|
4.30
|
|
5
|
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme.
|
Nat Struct Biol
|
1996
|
3.09
|
|
6
|
On the origin of bacterial resistance to penicillin: comparison of a beta-lactamase and a penicillin target.
|
Science
|
1986
|
2.88
|
|
7
|
Beta-lactamase of Bacillus licheniformis 749/C at 2 A resolution.
|
Proteins
|
1990
|
2.49
|
|
8
|
Mechanism of acyl transfer by the class A serine beta-lactamase of Streptomyces albus G.
|
Biochem J
|
1991
|
2.39
|
|
9
|
The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form.
|
J Mol Biol
|
2007
|
1.94
|
|
10
|
The crystal structure of the penicillin-binding protein 2x from Streptococcus pneumoniae and its acyl-enzyme form: implication in drug resistance.
|
J Mol Biol
|
2000
|
1.90
|
|
11
|
Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions.
|
Mol Cell
|
2000
|
1.77
|
|
12
|
Crystal structure of Proteus mirabilis PR catalase with and without bound NADPH.
|
J Mol Biol
|
1995
|
1.70
|
|
13
|
Structure of a Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase at 2.5 A resolution.
|
Nature
|
1982
|
1.60
|
|
14
|
1.85 A resolution structure of the zinc (II) beta-lactamase from Bacillus cereus.
|
Acta Crystallogr D Biol Crystallogr
|
1998
|
1.58
|
|
15
|
Crystallographic data for the beta-lactamase from Enterobacter cloacae P99.
|
J Mol Biol
|
1983
|
1.47
|
|
16
|
The kappa-carrageenase of P. carrageenovora features a tunnel-shaped active site: a novel insight in the evolution of Clan-B glycoside hydrolases.
|
Structure
|
2001
|
1.36
|
|
17
|
Mutations in the active site of penicillin-binding protein PBP2x from Streptococcus pneumoniae. Role in the specificity for beta-lactam antibiotics.
|
J Biol Chem
|
1999
|
1.34
|
|
18
|
Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril.
|
J Mol Biol
|
2003
|
1.33
|
|
19
|
Crystal structure of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-diaminopimelate ligase from Escherichia coli.
|
J Biol Chem
|
2000
|
1.31
|
|
20
|
Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations.
|
J Biol Chem
|
2001
|
1.29
|
|
21
|
Identification of a structural determinant for resistance to beta-lactam antibiotics in Gram-positive bacteria.
|
Proc Natl Acad Sci U S A
|
1998
|
1.27
|
|
22
|
Crystal structure of the human protein kinase CK2 regulatory subunit reveals its zinc finger-mediated dimerization.
|
EMBO J
|
1999
|
1.25
|
|
23
|
Engineering a novel beta-lactamase by a single point mutation.
|
Protein Eng
|
1990
|
1.23
|
|
24
|
Crystal structure of UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase from Escherichia coli.
|
EMBO J
|
1997
|
1.20
|
|
25
|
X-ray structure of the ZnII beta-lactamase from Bacteroides fragilis in an orthorhombic crystal form.
|
Acta Crystallogr D Biol Crystallogr
|
1998
|
1.17
|
|
26
|
Crystal structure study of Opsanus tau parvalbumin by multiwavelength anomalous diffraction.
|
FEBS Lett
|
1985
|
1.16
|
|
27
|
Identification, purification, and characterization of transpeptidase and glycosyltransferase domains of Streptococcus pneumoniae penicillin-binding protein 1a.
|
J Bacteriol
|
1998
|
1.14
|
|
28
|
Amino acid sequence of the penicillin-binding protein/DD-peptidase of Streptomyces K15. Predicted secondary structures of the low Mr penicillin-binding proteins of class A.
|
Biochem J
|
1991
|
1.13
|
|
29
|
Arginine 220 is a critical residue for the catalytic mechanism of the Streptomyces albus G beta-lactamase.
|
Protein Eng
|
1991
|
1.12
|
|
30
|
Properties and crystallization of a genetically engineered, water-soluble derivative of penicillin-binding protein 5 of Escherichia coli K12.
|
Eur J Biochem
|
1988
|
1.11
|
|
31
|
Site-directed mutagenesis of proposed active-site residues of penicillin-binding protein 5 from Escherichia coli.
|
Biochem J
|
1994
|
1.11
|
|
32
|
Crystal structure of Pseudomonas aeruginosa catabolic ornithine transcarbamoylase at 3.0-A resolution: a different oligomeric organization in the transcarbamoylase family.
|
Proc Natl Acad Sci U S A
|
1995
|
1.11
|
|
33
|
Primary and predicted secondary structures of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4.
|
Biochem J
|
1992
|
1.11
|
|
34
|
Determination of the MurD mechanism through crystallographic analysis of enzyme complexes.
|
J Mol Biol
|
1999
|
1.10
|
|
35
|
Crystallization and preliminary X-ray data for the exocellular beta-lactamase of Bacillus licheniformis 749/C.
|
J Mol Biol
|
1985
|
1.09
|
|
36
|
The structures and catalytic mechanisms of active-site serine beta-lactamases.
|
Biotechnol Genet Eng Rev
|
1994
|
1.09
|
|
37
|
Glycosyltransferase domain of penicillin-binding protein 2a from Streptococcus pneumoniae is membrane associated.
|
J Bacteriol
|
1999
|
1.05
|
|
38
|
Crystallization of a genetically engineered water-soluble primary penicillin target enzyme. The high molecular mass PBP2x of Streptococcus pneumoniae.
|
J Mol Biol
|
1993
|
1.05
|
|
39
|
Comparison of the structures of wild-type and a N313T mutant of Escherichia coli glyceraldehyde 3-phosphate dehydrogenases: implication for NAD binding and cooperativity.
|
J Mol Biol
|
1996
|
1.02
|
|
40
|
"Open" structures of MurD: domain movements and structural similarities with folylpolyglutamate synthetase.
|
J Mol Biol
|
2000
|
1.02
|
|
41
|
Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.
|
J Mol Biol
|
2007
|
1.01
|
|
42
|
Bacterial wall peptidoglycan, DD-peptidases and beta-lactam antibiotics.
|
Scand J Infect Dis Suppl
|
1984
|
0.99
|
|
43
|
The exocellular DD-carboxypeptidase of Streptomyces albus G: a metallo (Zn2+) enzyme.
|
FEBS Lett
|
1980
|
0.97
|
|
44
|
Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila.
|
Antimicrob Agents Chemother
|
2007
|
0.96
|
|
45
|
Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments.
|
Eur J Biochem
|
2001
|
0.94
|
|
46
|
Catabolic ornithine carbamoyltransferase of Pseudomonas aeruginosa. Importance of the N-terminal region for dodecameric structure and homotropic carbamoylphosphate cooperativity.
|
Eur J Biochem
|
1996
|
0.92
|
|
47
|
Role of the ortholog and paralog amino acid invariants in the active site of the UDP-MurNAc-L-alanine:D-glutamate ligase (MurD).
|
Biochemistry
|
1999
|
0.92
|
|
48
|
The iota-carrageenase of Alteromonas fortis. A beta-helix fold-containing enzyme for the degradation of a highly polyanionic polysaccharide.
|
J Biol Chem
|
2001
|
0.90
|
|
49
|
The 4.5 A resolution structure analysis of the exocellular DD-carboxypeptidase of Streptomyces albus G.
|
FEBS Lett
|
1980
|
0.89
|
|
50
|
Biochemical characterisation of ornithine carbamoyltransferase from Pyrococcus furiosus.
|
Eur J Biochem
|
1997
|
0.89
|
|
51
|
Molecular size and symmetry of Pseudomonas aeruginosa catabolic ornithine carbamoyltransferase. An X-ray crystallography analysis.
|
J Mol Biol
|
1991
|
0.86
|
|
52
|
Allosteric regulation in Pseudomonas aeruginosa catabolic ornithine carbamoyltransferase revisited: association of concerted homotropic cooperative interactions and local heterotropic effects.
|
J Mol Biol
|
1998
|
0.85
|
|
53
|
Preference of Cd(II) and Zn(II) for the two metal sites in Bacillus cereus beta-lactamase II: A perturbed angular correlation of gamma-rays spectroscopic study.
|
Biochemistry
|
1999
|
0.84
|
|
54
|
A crystallographic comparison between mutated glyceraldehyde-3-phosphate dehydrogenases from Bacillus stearothermophilus complexed with either NAD+ or NADP+.
|
J Mol Biol
|
1997
|
0.84
|
|
55
|
Processing and hydrolytic mechanism of the cgkA-encoded kappa-carrageenase of Alteromonas carrageenovora.
|
Eur J Biochem
|
1995
|
0.83
|
|
56
|
Catabolic ornithine carbamoyltransferase of Pseudomonas aeruginosa. Changes of allosteric properties resulting from modifications at the C-terminus.
|
Eur J Biochem
|
1994
|
0.83
|
|
57
|
Kinetic studies of allosteric catabolic ornithine carbamoyltransferase from Pseudomonas aeruginosa.
|
Eur J Biochem
|
1998
|
0.82
|
|
58
|
Methionine-321 in the C-terminal alpha-helix of catabolic ornithine carbamoyltransferase from Pseudomonas aeruginosa is important for positive homotropic cooperativity.
|
FEMS Microbiol Lett
|
1994
|
0.81
|
|
59
|
Crystallization and preliminary x-ray diffraction analysis of the regulatory subunit of human protein kinase CK2.
|
Acta Crystallogr D Biol Crystallogr
|
1999
|
0.80
|
|
60
|
Deacylation kinetics analysis of Streptococcus pneumoniae penicillin-binding protein 2x mutants resistant to beta-lactam antibiotics using electrospray ionization- mass spectrometry.
|
Anal Biochem
|
2000
|
0.80
|
|
61
|
Structural effects of the active site mutation cysteine to serine in Bacillus cereus zinc-beta-lactamase.
|
Protein Sci
|
2000
|
0.80
|
|
62
|
Large-scale preparation, purification, and crystallization of UDP-N-acetylmuramoyl-L-alanine: D-glutamate ligase from Escherichia coli.
|
Protein Expr Purif
|
1998
|
0.79
|
|
63
|
Purification, crystallization and preliminary X-ray analysis of Bacteroides fragilis Zn2+ beta-lactamase.
|
Acta Crystallogr D Biol Crystallogr
|
1997
|
0.79
|
|
64
|
Crystallographic data for the DD-carboxypeptidase-endopeptidase of low penicillin sensitivity excreted by Streptomyces albus g.
|
J Mol Biol
|
1979
|
0.79
|
|
65
|
Molecular mechanisms of antibiotic resistance in gram-positive pathogens.
|
Curr Drug Targets Infect Disord
|
2001
|
0.78
|
|
66
|
Study of the Zn-containing DD-carboxypeptidase of Streptomyces albus G by small-angle X-ray scattering in solution.
|
Eur J Biochem
|
1984
|
0.78
|
|
67
|
Use of a designed fusion protein dissociates allosteric properties from the dodecameric state of Pseudomonas aeruginosa catabolic ornithine carbamoyltransferase.
|
Proc Natl Acad Sci U S A
|
1996
|
0.78
|
|
68
|
Expression, purification, crystallization and preliminary x-ray analysis of the kappa-carrageenase from Pseudoalteromonas carrageenovora.
|
Acta Crystallogr D Biol Crystallogr
|
1999
|
0.76
|
|
69
|
Expression, purification, crystallization and preliminary X-ray analysis of the iota-carrageenase from Alteromonas fortis.
|
Acta Crystallogr D Biol Crystallogr
|
2000
|
0.76
|
|
70
|
Penicillin-recognizing enzymes.
|
Biochem Soc Trans
|
1988
|
0.76
|
|
71
|
Active-site-directed inactivators of the Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase of Streptomyces albus G.
|
Biochem J
|
1984
|
0.75
|
|
72
|
Crystallization and preliminary X-ray data for parvalbumin IIIf of Opsanus tau.
|
J Mol Biol
|
1981
|
0.75
|
|
73
|
Crystallographic studies of low penicillin-sensitive enzyme excreted by Streptomyces albus G [proceedings].
|
Arch Int Physiol Biochim
|
1979
|
0.75
|
|
74
|
Purification, crystallization and preliminary X-ray analysis of catabolic ornithine carbamoyltransferase from Pseudomonas aeruginosa.
|
Acta Crystallogr D Biol Crystallogr
|
1999
|
0.75
|
|
75
|
Possible hydrogen-bond interactions of steroid hormones--II. Corticosteroids.
|
J Steroid Biochem
|
1976
|
0.75
|
|
76
|
Primary and predicted secondary structure of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4.
|
Biochem J
|
1992
|
0.75
|
|
77
|
Crystallization and preliminary X-ray diffraction studies of Escherichia coli glyceraldehyde-3-phosphate dehydrogenase.
|
Acta Crystallogr D Biol Crystallogr
|
1995
|
0.75
|
|
78
|
Crystal and molecular structure of BN 52021, a PAF-acether antagonist. Comparison with the conformation of Kadsurenone and related compounds.
|
Pharmacol Res Commun
|
1986
|
0.75
|